| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the brinzolamide-6670 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 |
| AIM1L | absent in melanoma 1-like |
| ARHGDIA | Rho GDP dissociation inhibitor (GDI) alpha |
| AURKC | aurora kinase C |
| BAIAP2 | BAI1-associated protein 2 |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| BMPR1B | bone morphogenetic protein receptor, type IB |
| C17ORF53 | chromosome 17 open reading frame 53 |
| C3AR1 | complement component 3a receptor 1 |
| CACNG4 | calcium channel, voltage-dependent, gamma subunit 4 |
| CACYBP | calcyclin binding protein |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase |
| CCDC64 | coiled-coil domain containing 64 |
| CD68 | CD68 molecule |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CERS4 | ceramide synthase 4 |
| CITED1 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 |
| CLEC11A | C-type lectin domain family 11, member A |
| CSF1 | colony stimulating factor 1 (macrophage) |
| DEFA4 | defensin, alpha 4, corticostatin |
| DHRS12 | dehydrogenase/reductase (SDR family) member 12 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 |
| DLX2 | distal-less homeobox 2 |
| DNAJB12 | DnaJ (Hsp40) homolog, subfamily B, member 12 |
| EED | embryonic ectoderm development |
| EGFL7 | EGF-like-domain, multiple 7 |
| FERMT2 | fermitin family member 2 |
| FGF22 | fibroblast growth factor 22 |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GDPD3 | glycerophosphodiester phosphodiesterase domain containing 3 |
| GNRH1 | gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) |
| GPLD1 | glycosylphosphatidylinositol specific phospholipase D1 |
| GPR85 | G protein-coupled receptor 85 |
| GSN-AS1 | GSN antisense RNA 1 |
| GYPC | glycophorin C (Gerbich blood group) |
| GZMK | granzyme K (granzyme 3; tryptase II) |
| HSD17B1 | hydroxysteroid (17-beta) dehydrogenase 1 |
| HTR6 | 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein |
| IDS | iduronate 2-sulfatase |
| INPP5J | inositol polyphosphate-5-phosphatase J |
| IRF4 | interferon regulatory factor 4 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 |
| KCNK13 | potassium channel, two pore domain subfamily K, member 13 |
| KMT2A | lysine (K)-specific methyltransferase 2A |
| KRIT1 | KRIT1, ankyrin repeat containing |
| KRT17 | keratin 17, type I |
| LARP7 | La ribonucleoprotein domain family, member 7 |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LIMK2 | LIM domain kinase 2 |
| LOC100294391 | uncharacterized LOC100294391 |
| LRRK1 | leucine-rich repeat kinase 1 |
| MAPK11 | mitogen-activated protein kinase 11 |
| MC1R | melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) |
| MCF2L | MCF.2 cell line derived transforming sequence-like |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| NOTCH2 | notch 2 |
| NTM | neurotrimin |
| OAZ3 | ornithine decarboxylase antizyme 3 |
| OBSCN | obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF |
| OGFR | opioid growth factor receptor |
| OVOL2 | ovo-like zinc finger 2 |
| OXCT2 | 3-oxoacid CoA transferase 2 |
| PATZ1 | POZ (BTB) and AT hook containing zinc finger 1 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide |
| PGAP3 | post-GPI attachment to proteins 3 |
| PHF20L1 | PHD finger protein 20-like 1 |
| PLA2R1 | phospholipase A2 receptor 1, 180kDa |
| PLEKHG3 | pleckstrin homology domain containing, family G (with RhoGef domain) member 3 |
| PPP1R14D | protein phosphatase 1, regulatory (inhibitor) subunit 14D |
| PRAMEF11 | PRAME family member 11 |
| PSG1 | pregnancy specific beta-1-glycoprotein 1 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J |
| RASA3 | RAS p21 protein activator 3 |
| RETN | resistin |
| RPL35A | ribosomal protein L35a |
| SDHB | succinate dehydrogenase complex, subunit B, iron sulfur (Ip) |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) |
| SNX13 | sorting nexin 13 |
| STXBP5L | syntaxin binding protein 5-like |
| SYDE1 | synapse defective 1, Rho GTPase, homolog 1 (C. elegans) |
| TAPBPL | TAP binding protein-like |
| TBX5 | T-box 5 |
| TEX14 | testis expressed 14 |
| TMPRSS6 | transmembrane protease, serine 6 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TNPO2 | transportin 2 |
| TRIM15 | tripartite motif containing 15 |
| TRIM29 | tripartite motif containing 29 |
| TRMT44 | tRNA methyltransferase 44 homolog (S. cerevisiae) |
| WDR59 | WD repeat domain 59 |
| XIAP | X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase |
| ZKSCAN5 | zinc finger with KRAB and SCAN domains 5 |
| ZNF287 | zinc finger protein 287 |
| ZNF334 | zinc finger protein 334 |
| ZNF573 | zinc finger protein 573 |
| Symbol | Name |
|---|---|
| ABCC6 | ATP-binding cassette, sub-family C (CFTR/MRP), member 6 |
| ALPK1 | alpha-kinase 1 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) |
| ATAT1 | alpha tubulin acetyltransferase 1 |
| B4GALNT1 | beta-1,4-N-acetyl-galactosaminyl transferase 1 |
| BBC3 | BCL2 binding component 3 |
| BCL2L2 | BCL2-like 2 |
| C14ORF105 | chromosome 14 open reading frame 105 |
| C3 | complement component 3 |
| CD101 | CD101 molecule |
| CIDEC | cell death-inducing DFFA-like effector c |
| CLSPN | claspin |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| CNIH3 | cornichon family AMPA receptor auxiliary protein 3 |
| CSF1R | colony stimulating factor 1 receptor |
| CST1 | cystatin SN |
| CTSK | cathepsin K |
| CYP2B7P | cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene |
| CYP7B1 | cytochrome P450, family 7, subfamily B, polypeptide 1 |
| DENND5B | DENN/MADD domain containing 5B |
| ERCC2 | excision repair cross-complementation group 2 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| HIST1H2AK | histone cluster 1, H2ak |
| HOMER2 | homer scaffolding protein 2 |
| HOXA7 | homeobox A7 |
| HOXC13 | homeobox C13 |
| IFT140 | intraflagellar transport 140 |
| IFT54 | intraflagellar transport 54 |
| IL36RN | interleukin 36 receptor antagonist |
| ISYNA1 | inositol-3-phosphate synthase 1 |
| ITGB7 | integrin, beta 7 |
| KIAA0319L | KIAA0319-like |
| KIAA1456 | KIAA1456 |
| KLK7 | kallikrein-related peptidase 7 |
| KRT20 | keratin 20, type I |
| LAX1 | lymphocyte transmembrane adaptor 1 |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| LPPR1 | lipid phosphate phosphatase-related protein type 1 |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| MANBA | mannosidase, beta A, lysosomal |
| MAPK8IP1 | mitogen-activated protein kinase 8 interacting protein 1 |
| MED15 | mediator complex subunit 15 |
| MEGF8 | multiple EGF-like-domains 8 |
| MEIS1 | Meis homeobox 1 |
| MGAT4A | mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A |
| MTSS1L | metastasis suppressor 1-like |
| MXRA8 | matrix-remodelling associated 8 |
| N6AMT1 | N-6 adenine-specific DNA methyltransferase 1 (putative) |
| NAG18 | NAG18 mRNA |
| NEK11 | NIMA-related kinase 11 |
| NID2 | nidogen 2 (osteonidogen) |
| NKX3-2 | NK3 homeobox 2 |
| NUDT3 | nudix (nucleoside diphosphate linked moiety X)-type motif 3 |
| OR2F1 | olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) |
| PDE6C | phosphodiesterase 6C, cGMP-specific, cone, alpha prime |
| PER3 | period circadian clock 3 |
| PLD2 | phospholipase D2 |
| PLEKHG6 | pleckstrin homology domain containing, family G (with RhoGef domain) member 6 |
| PPT2 | palmitoyl-protein thioesterase 2 |
| PRSS53 | protease, serine, 53 |
| RAB40A | RAB40A, member RAS oncogene family |
| RAI2 | retinoic acid induced 2 |
| REM1 | RAS (RAD and GEM)-like GTP-binding 1 |
| RNF2 | ring finger protein 2 |
| ROM1 | retinal outer segment membrane protein 1 |
| RRNAD1 | ribosomal RNA adenine dimethylase domain containing 1 |
| SCN8A | sodium channel, voltage gated, type VIII alpha subunit |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 |
| SIX3 | SIX homeobox 3 |
| SLC16A10 | solute carrier family 16 (aromatic amino acid transporter), member 10 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 |
| SLC5A5 | solute carrier family 5 (sodium/iodide cotransporter), member 5 |
| SLC9A2 | solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 |
| SLITRK5 | SLIT and NTRK-like family, member 5 |
| SNORA21 | small nucleolar RNA, H/ACA box 21 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 |
| SULT2B1 | sulfotransferase family, cytosolic, 2B, member 1 |
| SYTL2 | synaptotagmin-like 2 |
| TCEB3B | transcription elongation factor B polypeptide 3B (elongin A2) |
| TIGD6 | tigger transposable element derived 6 |
| TLR2 | toll-like receptor 2 |
| TMEM180 | transmembrane protein 180 |
| TMEM183A | transmembrane protein 183A |
| TMSB15A | thymosin beta 15a |
| TNFSF12 | tumor necrosis factor (ligand) superfamily, member 12 |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| TUBA3C | tubulin, alpha 3c |
| USP20 | ubiquitin specific peptidase 20 |
| USP27X | ubiquitin specific peptidase 27, X-linked |
| VASH1 | vasohibin 1 |
| XYLT2 | xylosyltransferase II |
| ZCWPW1 | zinc finger, CW type with PWWP domain 1 |
| ZNF197 | zinc finger protein 197 |
| ZNF391 | zinc finger protein 391 |
| ZNF671 | zinc finger protein 671 |
| ZNF702P | zinc finger protein 702, pseudogene |
| ZNF747 | zinc finger protein 747 |
