bromocriptine-1507 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the bromocriptine-1507 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTL8 actin-like 8
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
ADRA1A adrenoceptor alpha 1A
AP2A2 adaptor-related protein complex 2, alpha 2 subunit
ARHGAP26 Rho GTPase activating protein 26
ARL4C ADP-ribosylation factor-like 4C
BHLHE41 basic helix-loop-helix family, member e41
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CACNA1S calcium channel, voltage-dependent, L type, alpha 1S subunit
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CCL22 chemokine (C-C motif) ligand 22
CCL23 chemokine (C-C motif) ligand 23
CD58 CD58 molecule
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLEC3B C-type lectin domain family 3, member B
CNTFR ciliary neurotrophic factor receptor
CPED1 cadherin-like and PC-esterase domain containing 1
CRELD1 cysteine-rich with EGF-like domains 1
CSHL1 chorionic somatomammotropin hormone-like 1
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
DDIT4 DNA-damage-inducible transcript 4
DEPDC5 DEP domain containing 5
DGKA diacylglycerol kinase, alpha 80kDa
DMTN dematin actin binding protein
EFNB3 ephrin-B3
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2
ELMO1 engulfment and cell motility 1
EN2 engrailed homeobox 2
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
FAM46C family with sequence similarity 46, member C
FAXDC2 fatty acid hydroxylase domain containing 2
GREB1 growth regulation by estrogen in breast cancer 1
HDAC7 histone deacetylase 7
HEXA hexosaminidase A (alpha polypeptide)
HHAT hedgehog acyltransferase
HOXC5 homeobox C5
HPX hemopexin
HRK harakiri, BCL2 interacting protein
INHBE inhibin, beta E
IRS4 insulin receptor substrate 4
ISG20L2 interferon stimulated exonuclease gene 20kDa-like 2
JUN jun proto-oncogene
KCNK5 potassium channel, two pore domain subfamily K, member 5
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KCTD17 potassium channel tetramerization domain containing 17
LEPR leptin receptor
LPXN leupaxin
LRRC37A3 leucine rich repeat containing 37, member A3
MAP2K5 mitogen-activated protein kinase kinase 5
MAPK10 mitogen-activated protein kinase 10
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2
MSL3 male-specific lethal 3 homolog (Drosophila)
MST1 macrophage stimulating 1
NEK9 NIMA-related kinase 9
NMT2 N-myristoyltransferase 2
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
OLFML2A olfactomedin-like 2A
OLFML2B olfactomedin-like 2B
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PDIA2 protein disulfide isomerase family A, member 2
PER1 period circadian clock 1
PHLDB1 pleckstrin homology-like domain, family B, member 1
PLK3 polo-like kinase 3
PML promyelocytic leukemia
POU1F1 POU class 1 homeobox 1
PPIA peptidylprolyl isomerase A (cyclophilin A)
PRODH proline dehydrogenase (oxidase) 1
PTGIS prostaglandin I2 (prostacyclin) synthase
PTK2B protein tyrosine kinase 2 beta
PTPRS protein tyrosine phosphatase, receptor type, S
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RNF126P1 ring finger protein 126 pseudogene 1
S100A13 S100 calcium binding protein A13
SCNN1B sodium channel, non voltage gated 1 beta subunit
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
SRRT serrate, RNA effector molecule
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TERT telomerase reverse transcriptase
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TMEM242 transmembrane protein 242
TNN tenascin N
TRIM2 tripartite motif containing 2
TRIM3 tripartite motif containing 3
TUBA3C tubulin, alpha 3c
USB1 U6 snRNA biogenesis 1
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
VN1R1 vomeronasal 1 receptor 1
WNT1 wingless-type MMTV integration site family, member 1
WNT6 wingless-type MMTV integration site family, member 6
ZBTB43 zinc finger and BTB domain containing 43
ZCCHC14 zinc finger, CCHC domain containing 14
ZNF79 zinc finger protein 79

decreased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ACAD10 acyl-CoA dehydrogenase family, member 10
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma
ARL15 ADP-ribosylation factor-like 15
ARMC4 armadillo repeat containing 4
ATAD5 ATPase family, AAA domain containing 5
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
BAX BCL2-associated X protein
C1ORF115 chromosome 1 open reading frame 115
CCNO cyclin O
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CENPC centromere protein C
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
CLCN5 chloride channel, voltage-sensitive 5
CLSTN2 calsyntenin 2
CTSF cathepsin F
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DNA2 DNA replication helicase/nuclease 2
ERF Ets2 repressor factor
F3 coagulation factor III (thromboplastin, tissue factor)
FAAH fatty acid amide hydrolase
FAM131A family with sequence similarity 131, member A
FAM13B family with sequence similarity 13, member B
FASTKD5 FAST kinase domains 5
FBXL6 F-box and leucine-rich repeat protein 6
FLJ22184
FOSL1 FOS-like antigen 1
GDAP2 ganglioside induced differentiation associated protein 2
GMPR guanosine monophosphate reductase
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GNL2 guanine nucleotide binding protein-like 2 (nucleolar)
GRPR gastrin-releasing peptide receptor
HIST1H2BI histone cluster 1, H2bi
HMOX1 heme oxygenase 1
HOOK1 hook microtubule-tethering protein 1
HYAL2 hyaluronoglucosaminidase 2
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
IRAK4 interleukin-1 receptor-associated kinase 4
IRF2BP1 interferon regulatory factor 2 binding protein 1
JUNB jun B proto-oncogene
KDM5C lysine (K)-specific demethylase 5C
KIF16B kinesin family member 16B
KLHL26 kelch-like family member 26
KLK5 kallikrein-related peptidase 5
LMNB1 lamin B1
LOC730101 uncharacterized LOC730101
LRRC61 leucine rich repeat containing 61
LZTS3 leucine zipper, putative tumor suppressor family member 3
MBOAT2 membrane bound O-acyltransferase domain containing 2
MCOLN1 mucolipin 1
MEFV Mediterranean fever
METTL16 methyltransferase like 16
MIS18BP1 MIS18 binding protein 1
MON1B MON1 secretory trafficking family member B
NDE1 nudE neurodevelopment protein 1
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NKAIN1 Na+/K+ transporting ATPase interacting 1
NKRF NFKB repressing factor
NPIPB15 nuclear pore complex interacting protein family, member B15
NPY5R neuropeptide Y receptor Y5
OSMR oncostatin M receptor
PARPBP PARP1 binding protein
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PLEKHO1 pleckstrin homology domain containing, family O member 1
PODXL2 podocalyxin-like 2
PRR14L proline rich 14-like
PTPN9 protein tyrosine phosphatase, non-receptor type 9
RAB30 RAB30, member RAS oncogene family
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RPAP2 RNA polymerase II associated protein 2
SDC3 syndecan 3
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SKA1 spindle and kinetochore associated complex subunit 1
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC35F5 solute carrier family 35, member F5
SNHG20 small nucleolar RNA host gene 20
TFF2 trefoil factor 2
THRAP3 thyroid hormone receptor associated protein 3
TMEM104 transmembrane protein 104
TMEM180 transmembrane protein 180
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TNRC6B trinucleotide repeat containing 6B
TNS2 tensin 2
TRAIP TRAF interacting protein
TRMT13 tRNA methyltransferase 13 homolog (S. cerevisiae)
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
ZBTB22 zinc finger and BTB domain containing 22
ZNF134 zinc finger protein 134
ZNF250 zinc finger protein 250
ZNF428 zinc finger protein 428
ZNF747 zinc finger protein 747
ZNF76 zinc finger protein 76