bromocriptine-2007 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the bromocriptine-2007 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADD3 adducin 3 (gamma)
ADGRG3 adhesion G protein-coupled receptor G3
ANXA1 annexin A1
APOLD1 apolipoprotein L domain containing 1
ARL4C ADP-ribosylation factor-like 4C
ARNT aryl hydrocarbon receptor nuclear translocator
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1
AXL AXL receptor tyrosine kinase
BCL3 B-cell CLL/lymphoma 3
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CCL20 chemokine (C-C motif) ligand 20
CCNG2 cyclin G2
CD38 CD38 molecule
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CD58 CD58 molecule
CD86 CD86 molecule
CDK19 cyclin-dependent kinase 19
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CDS2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2
CER1 cerberus 1, DAN family BMP antagonist
CHN2 chimerin 2
COL4A2 collagen, type IV, alpha 2
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CREM cAMP responsive element modulator
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CTSB cathepsin B
CYTH1 cytohesin 1
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial
DNAH17 dynein, axonemal, heavy chain 17
DOCK4 dedicator of cytokinesis 4
DUS4L dihydrouridine synthase 4-like (S. cerevisiae)
EPB41L3 erythrocyte membrane protein band 4.1-like 3
FAM13A family with sequence similarity 13, member A
FAM49B family with sequence similarity 49, member B
FLRT2 fibronectin leucine rich transmembrane protein 2
FTH1 ferritin, heavy polypeptide 1
FTH1P5 ferritin, heavy polypeptide 1 pseudogene 5
GALC galactosylceramidase
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GPR183 G protein-coupled receptor 183
HIST1H2AC histone cluster 1, H2ac
HLA-DMA major histocompatibility complex, class II, DM alpha
HLA-DRA major histocompatibility complex, class II, DR alpha
IFI30 interferon, gamma-inducible protein 30
IL10RB interleukin 10 receptor, beta
IL1R1 interleukin 1 receptor, type I
KIAA0430 KIAA0430
KIAA1109 KIAA1109
KYNU kynureninase
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
LITAF lipopolysaccharide-induced TNF factor
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MCTP2 multiple C2 domains, transmembrane 2
MEF2C myocyte enhancer factor 2C
MT1E metallothionein 1E
MT2A metallothionein 2A
MX2 MX dynamin-like GTPase 2
NINJ1 ninjurin 1
OCEL1 occludin/ELL domain containing 1
PDE3B phosphodiesterase 3B, cGMP-inhibited
PDE4B phosphodiesterase 4B, cAMP-specific
PDE4D phosphodiesterase 4D, cAMP-specific
PECAM1 platelet/endothelial cell adhesion molecule 1
PHYH phytanoyl-CoA 2-hydroxylase
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLSCR1 phospholipid scramblase 1
POLD4 polymerase (DNA-directed), delta 4, accessory subunit
PPARD peroxisome proliferator-activated receptor delta
PPP1R16B protein phosphatase 1, regulatory subunit 16B
PTCRA pre T-cell antigen receptor alpha
PTPRC protein tyrosine phosphatase, receptor type, C
RAB31 RAB31, member RAS oncogene family
RIN3 Ras and Rab interactor 3
RNF19B ring finger protein 19B
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SAT1 spermidine/spermine N1-acetyltransferase 1
SDC2 syndecan 2
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SH2D2A SH2 domain containing 2A
SH3BP5 SH3-domain binding protein 5 (BTK-associated)
SIPA1L1 signal-induced proliferation-associated 1 like 1
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SLC22A18 solute carrier family 22, member 18
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SMOX spermine oxidase
SPTAN1 spectrin, alpha, non-erythrocytic 1
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)
STAT4 signal transducer and activator of transcription 4
STX5 syntaxin 5
STXBP1 syntaxin binding protein 1
TGM5 transglutaminase 5
THBS1 thrombospondin 1
TIMP1 TIMP metallopeptidase inhibitor 1
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TREM1 triggering receptor expressed on myeloid cells 1
TSPAN31 tetraspanin 31
WIPI1 WD repeat domain, phosphoinositide interacting 1

decreased expression

Symbol Name
ABCE1 ATP-binding cassette, sub-family E (OABP), member 1
ACACA acetyl-CoA carboxylase alpha
ADGRA3 adhesion G protein-coupled receptor A3
ADRB2 adrenoceptor beta 2, surface
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)
ANKRD40 ankyrin repeat domain 40
BATF3 basic leucine zipper transcription factor, ATF-like 3
C10ORF2 chromosome 10 open reading frame 2
C8ORF33 chromosome 8 open reading frame 33
CA2 carbonic anhydrase II
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
CBR1 carbonyl reductase 1
CBS cystathionine-beta-synthase
CCDC86 coiled-coil domain containing 86
CCNA1 cyclin A1
CD3EAP CD3e molecule, epsilon associated protein
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12
CISH cytokine inducible SH2-containing protein
CTPS1 CTP synthase 1
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21
DDX56 DEAD (Asp-Glu-Ala-Asp) box helicase 56
DEXI Dexi homolog (mouse)
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila)
DNAAF2 dynein, axonemal, assembly factor 2
EBNA1BP2 EBNA1 binding protein 2
EIF2B3 eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa
ENDOG endonuclease G
EXOSC5 exosome component 5
FAM216A family with sequence similarity 216, member A
FARSA phenylalanyl-tRNA synthetase, alpha subunit
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
GNL3 guanine nucleotide binding protein-like 3 (nucleolar)
HIRA histone cell cycle regulator
HRAS Harvey rat sarcoma viral oncogene homolog
HSPB1 heat shock 27kDa protein 1
IDH3A isocitrate dehydrogenase 3 (NAD+) alpha
IFRD2 interferon-related developmental regulator 2
IRF8 interferon regulatory factor 8
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
KIAA0020 KIAA0020
KLHL21 kelch-like family member 21
LAMP5 lysosomal-associated membrane protein family, member 5
LAS1L LAS1-like (S. cerevisiae)
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
LRP3 low density lipoprotein receptor-related protein 3
MAK16 MAK16 homolog (S. cerevisiae)
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5
MRPL12 mitochondrial ribosomal protein L12
MRPL4 mitochondrial ribosomal protein L4
MRTO4 mRNA turnover 4 homolog (S. cerevisiae)
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase
MYBBP1A MYB binding protein (P160) 1a
MYC v-myc avian myelocytomatosis viral oncogene homolog
NDUFAF4 NADH dehydrogenase (ubiquinone) complex I, assembly factor 4
NIP7 NIP7, nucleolar pre-rRNA processing protein
NOC3L nucleolar complex associated 3 homolog (S. cerevisiae)
NOC4L nucleolar complex associated 4 homolog (S. cerevisiae)
NOL6 nucleolar protein 6 (RNA-associated)
NOLC1 nucleolar and coiled-body phosphoprotein 1
NTHL1 nth endonuclease III-like 1 (E. coli)
NUP93 nucleoporin 93kDa
PCSK7 proprotein convertase subtilisin/kexin type 7
PES1 pescadillo ribosomal biogenesis factor 1
PFAS phosphoribosylformylglycinamidine synthase
PFDN2 prefoldin subunit 2
POLR3K polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa
PPAN peter pan homolog (Drosophila)
PRDX4 peroxiredoxin 4
PRTN3 proteinase 3
PSAT1 phosphoserine aminotransferase 1
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2
PUS1 pseudouridylate synthase 1
PUS7 pseudouridylate synthase 7 (putative)
PWP2 PWP2 periodic tryptophan protein homolog (yeast)
REXO4 REX4, RNA exonuclease 4 homolog (S. cerevisiae)
RPIA ribose 5-phosphate isomerase A
RPP40 ribonuclease P/MRP 40kDa subunit
RRP9 ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)
RUVBL1 RuvB-like AAA ATPase 1
SCO2 SCO2 cytochrome c oxidase assembly protein
SDCCAG3 serologically defined colon cancer antigen 3
SDF2L1 stromal cell-derived factor 2-like 1
SLC17A9 solute carrier family 17 (vesicular nucleotide transporter), member 9
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2
SLC39A14 solute carrier family 39 (zinc transporter), member 14
SLC39A4 solute carrier family 39 (zinc transporter), member 4
SLCO4A1 solute carrier organic anion transporter family, member 4A1
SPP1 secreted phosphoprotein 1
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TIMM13 translocase of inner mitochondrial membrane 13 homolog (yeast)
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
UTP6 UTP6, small subunit (SSU) processome component, homolog (yeast)
WDR12 WD repeat domain 12
WDR3 WD repeat domain 3
WDR46 WD repeat domain 46
ZNF593 zinc finger protein 593
ZNF8 zinc finger protein 8