bromocriptine-4604 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the bromocriptine-4604 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ALDOB aldolase B, fructose-bisphosphate
ALK anaplastic lymphoma receptor tyrosine kinase
ARHGAP26 Rho GTPase activating protein 26
ARHGAP28 Rho GTPase activating protein 28
ARHGAP35 Rho GTPase activating protein 35
ARID3A AT rich interactive domain 3A (BRIGHT-like)
BDKRB1 bradykinin receptor B1
BGN biglycan
C1ORF61 chromosome 1 open reading frame 61
C2CD2L C2CD2-like
C3AR1 complement component 3a receptor 1
CABP5 calcium binding protein 5
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1
CELA2A chymotrypsin-like elastase family, member 2A
CNTFR ciliary neurotrophic factor receptor
COL3A1 collagen, type III, alpha 1
COQ7 coenzyme Q7 homolog, ubiquinone (yeast)
CRYGD crystallin, gamma D
DKKL1 dickkopf-like 1
DNAI2 dynein, axonemal, intermediate chain 2
DOK3 docking protein 3
EBF2 early B-cell factor 2
EDA ectodysplasin A
EDNRA endothelin receptor type A
EFS embryonal Fyn-associated substrate
ERN2 endoplasmic reticulum to nucleus signaling 2
ETV1 ets variant 1
FAM134B family with sequence similarity 134, member B
FFAR2 free fatty acid receptor 2
FGF18 fibroblast growth factor 18
FGF21 fibroblast growth factor 21
GADD45GIP1 growth arrest and DNA-damage-inducible, gamma interacting protein 1
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GLS glutaminase
GNG4 guanine nucleotide binding protein (G protein), gamma 4
HMG20B high mobility group 20B
IBA57 IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
IGH immunoglobulin heavy locus
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
KCNC1 potassium channel, voltage gated Shaw related subfamily C, member 1
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
KLRB1 killer cell lectin-like receptor subfamily B, member 1
LILRA1 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1
LINC00652 long intergenic non-protein coding RNA 652
LRRC32 leucine rich repeat containing 32
LY6G6C lymphocyte antigen 6 complex, locus G6C
LYRM9 LYR motif containing 9
MAST2 microtubule associated serine/threonine kinase 2
MCM3AP minichromosome maintenance complex component 3 associated protein
MFAP3L microfibrillar-associated protein 3-like
MR1 major histocompatibility complex, class I-related
MSR1 macrophage scavenger receptor 1
MVB12B multivesicular body subunit 12B
N4BP2L2-IT2 N4BPL2 intronic transcript 2
NCLN nicalin
NDUFA2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa
NEK11 NIMA-related kinase 11
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NPY4R neuropeptide Y receptor Y4
OPCML opioid binding protein/cell adhesion molecule-like
OTOF otoferlin
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PAEP progestagen-associated endometrial protein
PAX8 paired box 8
PCSK6 proprotein convertase subtilisin/kexin type 6
PDGFA platelet-derived growth factor alpha polypeptide
PHF20L1 PHD finger protein 20-like 1
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
POU1F1 POU class 1 homeobox 1
PRB4 proline-rich protein BstNI subfamily 4
PRF1 perforin 1 (pore forming protein)
PRPH peripherin
PTPRF protein tyrosine phosphatase, receptor type, F
RAB26 RAB26, member RAS oncogene family
RANBP1 RAN binding protein 1
RNF126P1 ring finger protein 126 pseudogene 1
SEPP1 selenoprotein P, plasma, 1
SGK2 serum/glucocorticoid regulated kinase 2
SIGLEC8 sialic acid binding Ig-like lectin 8
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SNCG synuclein, gamma (breast cancer-specific protein 1)
SP110 SP110 nuclear body protein
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
TAPBPL TAP binding protein-like
TMOD1 tropomodulin 1
TRPM1 transient receptor potential cation channel, subfamily M, member 1
TSHR thyroid stimulating hormone receptor
TTC22 tetratricopeptide repeat domain 22
VAMP5 vesicle-associated membrane protein 5
VAPB VAMP (vesicle-associated membrane protein)-associated protein B and C
VCAN versican
VIPR2 vasoactive intestinal peptide receptor 2
VPS41 vacuolar protein sorting 41 homolog (S. cerevisiae)
VSX1 visual system homeobox 1
ZC2HC1C zinc finger, C2HC-type containing 1C
ZNF471 zinc finger protein 471

decreased expression

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ADAM15 ADAM metallopeptidase domain 15
ADAT1 adenosine deaminase, tRNA-specific 1
ADGRA3 adhesion G protein-coupled receptor A3
AFAP1 actin filament associated protein 1
AHDC1 AT hook, DNA binding motif, containing 1
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
AKT1 v-akt murine thymoma viral oncogene homolog 1
ANG angiogenin, ribonuclease, RNase A family, 5
APOLD1 apolipoprotein L domain containing 1
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
ARRB2 arrestin, beta 2
ASCC2 activating signal cointegrator 1 complex subunit 2
BCORL1 BCL6 corepressor-like 1
C7ORF69 chromosome 7 open reading frame 69
CA5BP1 carbonic anhydrase VB pseudogene 1
CBX8 chromobox homolog 8
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CENPT centromere protein T
CGA glycoprotein hormones, alpha polypeptide
CHD8 chromodomain helicase DNA binding protein 8
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CLCF1 cardiotrophin-like cytokine factor 1
CLDN4 claudin 4
CLSPN claspin
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
DEAF1 DEAF1 transcription factor
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DNM3 dynamin 3
ETNK2 ethanolamine kinase 2
FAM110B family with sequence similarity 110, member B
FZD8 frizzled class receptor 8
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GPR176 G protein-coupled receptor 176
HLA-J major histocompatibility complex, class I, J (pseudogene)
HMHA1 histocompatibility (minor) HA-1
HYMAI hydatidiform mole associated and imprinted (non-protein coding)
INF2 inverted formin, FH2 and WH2 domain containing
IRF1 interferon regulatory factor 1
KCTD20 potassium channel tetramerization domain containing 20
KIAA0513 KIAA0513
KLF13 Kruppel-like factor 13
LINC00341 long intergenic non-protein coding RNA 341
MAN2C1 mannosidase, alpha, class 2C, member 1
MBIP MAP3K12 binding inhibitory protein 1
MBTPS2 membrane-bound transcription factor peptidase, site 2
MCOLN1 mucolipin 1
MFSD11 major facilitator superfamily domain containing 11
MX1 MX dynamin-like GTPase 1
NDP Norrie disease (pseudoglioma)
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NOL12 nucleolar protein 12
NUPR1 nuclear protein, transcriptional regulator, 1
OR1G1 olfactory receptor, family 1, subfamily G, member 1
PAK6 p21 protein (Cdc42/Rac)-activated kinase 6
PECR peroxisomal trans-2-enoyl-CoA reductase
PES1 pescadillo ribosomal biogenesis factor 1
PID1 phosphotyrosine interaction domain containing 1
PLAC8 placenta-specific 8
PLAG1 pleiomorphic adenoma gene 1
PLEKHJ1 pleckstrin homology domain containing, family J member 1
PLEKHO1 pleckstrin homology domain containing, family O member 1
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit
POLE polymerase (DNA directed), epsilon, catalytic subunit
POLL polymerase (DNA directed), lambda
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha
PTK7 protein tyrosine kinase 7 (inactive)
PTPN14 protein tyrosine phosphatase, non-receptor type 14
RUSC2 RUN and SH3 domain containing 2
SCIN scinderin
SCN1B sodium channel, voltage gated, type I beta subunit
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC35F6 solute carrier family 35, member F6
SLIT2 slit homolog 2 (Drosophila)
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SNIP1 Smad nuclear interacting protein 1
SREK1IP1 SREK1-interacting protein 1
STX1A syntaxin 1A (brain)
SUGP1 SURP and G patch domain containing 1
SYTL2 synaptotagmin-like 2
TCTN2 tectonic family member 2
THBS3 thrombospondin 3
THOP1 thimet oligopeptidase 1
TLN1 talin 1
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TPST1 tyrosylprotein sulfotransferase 1
TUBA3C tubulin, alpha 3c
TUBG2 tubulin, gamma 2
ZFAND3 zinc finger, AN1-type domain 3
ZMAT5 zinc finger, matrin-type 5
ZNF276 zinc finger protein 276
ZNF606 zinc finger protein 606
ZNF692 zinc finger protein 692
ZNF816 zinc finger protein 816
ZNF839 zinc finger protein 839
ZSCAN26 zinc finger and SCAN domain containing 26