bromopride-2182 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the bromopride-2182 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GNT alpha-1,4-N-acetylglucosaminyltransferase
ACKR1 atypical chemokine receptor 1 (Duffy blood group)
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ADORA1 adenosine A1 receptor
AHNAK AHNAK nucleoprotein
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
APAF1 apoptotic peptidase activating factor 1
APBA3 amyloid beta (A4) precursor protein-binding, family A, member 3
APOE apolipoprotein E
ATAT1 alpha tubulin acetyltransferase 1
B9D1 B9 protein domain 1
BGN biglycan
BMP10 bone morphogenetic protein 10
BTN3A1 butyrophilin, subfamily 3, member A1
C1ORF61 chromosome 1 open reading frame 61
C20ORF27 chromosome 20 open reading frame 27
C3ORF52 chromosome 3 open reading frame 52
CD80 CD80 molecule
CDK10 cyclin-dependent kinase 10
CTIF CBP80/20-dependent translation initiation factor
CXCR3 chemokine (C-X-C motif) receptor 3
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
CYP4F2 cytochrome P450, family 4, subfamily F, polypeptide 2
DENND2A DENN/MADD domain containing 2A
DSPP dentin sialophosphoprotein
DTX2 deltex 2, E3 ubiquitin ligase
EPHB1 EPH receptor B1
ETV7 ets variant 7
FKBP8 FK506 binding protein 8, 38kDa
FLJ11292
FYB FYN binding protein
GAP43 growth associated protein 43
GDAP1L1 ganglioside induced differentiation associated protein 1-like 1
GJA9 gap junction protein, alpha 9, 59kDa
GRIP2 glutamate receptor interacting protein 2
HEG1 heart development protein with EGF-like domains 1
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HOXA10 homeobox A10
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
IL1R1 interleukin 1 receptor, type I
IQSEC1 IQ motif and Sec7 domain 1
ISG20 interferon stimulated exonuclease gene 20kDa
KIDINS220 kinase D-interacting substrate, 220kDa
KLRG1 killer cell lectin-like receptor subfamily G, member 1
KRT85 keratin 85, type II
KSR1 kinase suppressor of ras 1
MAML3 mastermind-like 3 (Drosophila)
MARC1 mitochondrial amidoxime reducing component 1
MERTK MER proto-oncogene, tyrosine kinase
MFAP3L microfibrillar-associated protein 3-like
MOB3B MOB kinase activator 3B
MT1G metallothionein 1G
NDRG2 NDRG family member 2
NOVA2 neuro-oncological ventral antigen 2
NTN1 netrin 1
NUP188 nucleoporin 188kDa
PDE4C phosphodiesterase 4C, cAMP-specific
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
PGBD5 piggyBac transposable element derived 5
PHF20L1 PHD finger protein 20-like 1
PID1 phosphotyrosine interaction domain containing 1
PLSCR3 phospholipid scramblase 3
PML promyelocytic leukemia
POU2F2 POU class 2 homeobox 2
PPP1R14D protein phosphatase 1, regulatory (inhibitor) subunit 14D
PROS1 protein S (alpha)
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTPRF protein tyrosine phosphatase, receptor type, F
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
REEP2 receptor accessory protein 2
SEZ6L seizure related 6 homolog (mouse)-like
SIPA1L1 signal-induced proliferation-associated 1 like 1
SLAMF7 SLAM family member 7
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5
SLC24A2 solute carrier family 24 (sodium/potassium/calcium exchanger), member 2
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLN sarcolipin
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SOX9 SRY (sex determining region Y)-box 9
SPANXC SPANX family, member C
SPRR1B small proline-rich protein 1B
SPTA1 spectrin, alpha, erythrocytic 1
SRPK2 SRSF protein kinase 2
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TAT tyrosine aminotransferase
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TEX15 testis expressed 15
TGFB1I1 transforming growth factor beta 1 induced transcript 1
THPO thrombopoietin
TLN2 talin 2
TMPRSS15 transmembrane protease, serine 15
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TNFRSF9 tumor necrosis factor receptor superfamily, member 9
TPSG1 tryptase gamma 1
VPREB3 pre-B lymphocyte 3
YOD1 YOD1 deubiquitinase
ZNF518A zinc finger protein 518A
ZNF609 zinc finger protein 609

decreased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ACOX2 acyl-CoA oxidase 2, branched chain
ADGRG2 adhesion G protein-coupled receptor G2
ARHGAP10 Rho GTPase activating protein 10
ASGR2 asialoglycoprotein receptor 2
BATF basic leucine zipper transcription factor, ATF-like
BGLAP bone gamma-carboxyglutamate (gla) protein
BPI bactericidal/permeability-increasing protein
C14ORF93 chromosome 14 open reading frame 93
C22ORF29 chromosome 22 open reading frame 29
C7ORF43 chromosome 7 open reading frame 43
CAPN15 calpain 15
CD37 CD37 molecule
CD9 CD9 molecule
COQ6 coenzyme Q6 monooxygenase
DGAT1 diacylglycerol O-acyltransferase 1
DOCK4 dedicator of cytokinesis 4
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EPHA4 EPH receptor A4
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
ERCC2 excision repair cross-complementation group 2
EXOSC1 exosome component 1
FOSB FBJ murine osteosarcoma viral oncogene homolog B
GK3P glycerol kinase 3 pseudogene
GLCE glucuronic acid epimerase
GMEB1 glucocorticoid modulatory element binding protein 1
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GSTCD glutathione S-transferase, C-terminal domain containing
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HHLA3 HERV-H LTR-associating 3
HIST1H1T histone cluster 1, H1t
IFI6 interferon, alpha-inducible protein 6
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
IL11RA interleukin 11 receptor, alpha
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
LINC00597 long intergenic non-protein coding RNA 597
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAPK3 mitogen-activated protein kinase 3
MKL2 MKL/myocardin-like 2
MTHFS 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
MTHFSD methenyltetrahydrofolate synthetase domain containing
MVD mevalonate (diphospho) decarboxylase
MXD3 MAX dimerization protein 3
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
NIPAL2 NIPA-like domain containing 2
PADI1 peptidyl arginine deiminase, type I
PCDHGA10 protocadherin gamma subfamily A, 10
PENK proenkephalin
PGPEP1 pyroglutamyl-peptidase I
PIGH phosphatidylinositol glycan anchor biosynthesis, class H
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLP1 proteolipid protein 1
PLTP phospholipid transfer protein
PRAMEF11 PRAME family member 11
RNF121 ring finger protein 121
RNF126P1 ring finger protein 126 pseudogene 1
RPL10L ribosomal protein L10-like
RPL13P5 ribosomal protein L13 pseudogene 5
RUSC2 RUN and SH3 domain containing 2
SAMD9 sterile alpha motif domain containing 9
SBNO2 strawberry notch homolog 2 (Drosophila)
SGCE sarcoglycan, epsilon
SIDT1 SID1 transmembrane family, member 1
SIK1 salt-inducible kinase 1
SLC35E3 solute carrier family 35, member E3
SLC35F6 solute carrier family 35, member F6
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SP1 Sp1 transcription factor
SPATA20 spermatogenesis associated 20
SPINT1 serine peptidase inhibitor, Kunitz type 1
SREBF1 sterol regulatory element binding transcription factor 1
STAG3L4 stromal antigen 3-like 4 (pseudogene)
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TAGLN transgelin
TESK1 testis-specific kinase 1
TLR8 toll-like receptor 8
TMEM104 transmembrane protein 104
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TRAF1 TNF receptor-associated factor 1
TRIM26 tripartite motif containing 26
USP6NL USP6 N-terminal like
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
VSIG10 V-set and immunoglobulin domain containing 10
XYLT2 xylosyltransferase II
ZBED1 zinc finger, BED-type containing 1
ZNF16 zinc finger protein 16
ZNF254 zinc finger protein 254
ZNF304 zinc finger protein 304
ZNF528 zinc finger protein 528
ZNF667 zinc finger protein 667
ZNF668 zinc finger protein 668
ZNF675 zinc finger protein 675
ZNF76 zinc finger protein 76