bromopride-3617 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the bromopride-3617 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM28 ADAM metallopeptidase domain 28
AGXT alanine-glyoxylate aminotransferase
AKR1C4 aldo-keto reductase family 1, member C4
ARG1 arginase 1
ATP10B ATPase, class V, type 10B
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CALB2 calbindin 2
CAPN2 calpain 2, (m/II) large subunit
CCDC64 coiled-coil domain containing 64
CCL22 chemokine (C-C motif) ligand 22
CD200 CD200 molecule
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CHST4 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4
COL6A1 collagen, type VI, alpha 1
CYLD cylindromatosis (turban tumor syndrome)
CYTH4 cytohesin 4
DCTN2 dynactin 2 (p50)
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DGAT1 diacylglycerol O-acyltransferase 1
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DUSP13 dual specificity phosphatase 13
ECE1 endothelin converting enzyme 1
ELOVL2 ELOVL fatty acid elongase 2
EMP1 epithelial membrane protein 1
ERCC2 excision repair cross-complementation group 2
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
FABP7 fatty acid binding protein 7, brain
FGF16 fibroblast growth factor 16
FKRP fukutin related protein
FN1 fibronectin 1
FSHB follicle stimulating hormone, beta polypeptide
GFER growth factor, augmenter of liver regeneration
GJD2 gap junction protein, delta 2, 36kDa
GK glycerol kinase
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
GYG2 glycogenin 2
HCLS1 hematopoietic cell-specific Lyn substrate 1
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HOXB3 homeobox B3
ICOS inducible T-cell co-stimulator
IFNW1 interferon, omega 1
IL1RN interleukin 1 receptor antagonist
IRF4 interferon regulatory factor 4
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KIR3DX1 killer cell immunoglobulin-like receptor, three domains, X1
KLHDC8A kelch domain containing 8A
LAMA2 laminin, alpha 2
LGALS8 lectin, galactoside-binding, soluble, 8
LINC00574 long intergenic non-protein coding RNA 574
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LZTS3 leucine zipper, putative tumor suppressor family member 3
MCAM melanoma cell adhesion molecule
MINK1 misshapen-like kinase 1
MLXIPL MLX interacting protein-like
NIPAL3 NIPA-like domain containing 3
NOX5 NADPH oxidase, EF-hand calcium binding domain 5
NR6A1 nuclear receptor subfamily 6, group A, member 1
OR1A1 olfactory receptor, family 1, subfamily A, member 1
PAX2 paired box 2
PAX3 paired box 3
PAX8 paired box 8
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PLTP phospholipid transfer protein
PLXNB3 plexin B3
PRUNE2 prune homolog 2 (Drosophila)
PRY PTPN13-like, Y-linked
PTK7 protein tyrosine kinase 7 (inactive)
PVRIG poliovirus receptor related immunoglobulin domain containing
PXDC1 PX domain containing 1
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
REEP2 receptor accessory protein 2
RFXAP regulatory factor X-associated protein
RGSL1 regulator of G-protein signaling like 1
RPL3L ribosomal protein L3-like
RPS4Y1 ribosomal protein S4, Y-linked 1
RRP8 ribosomal RNA processing 8, methyltransferase, homolog (yeast)
RUNX1 runt-related transcription factor 1
SCN4A sodium channel, voltage gated, type IV alpha subunit
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
STAT2 signal transducer and activator of transcription 2, 113kDa
SYNPO synaptopodin
TACC1 transforming, acidic coiled-coil containing protein 1
TBXA2R thromboxane A2 receptor
TGFA transforming growth factor, alpha
THBS1 thrombospondin 1
THRB thyroid hormone receptor, beta
TMC6 transmembrane channel-like 6
TRIM29 tripartite motif containing 29
UBA6 ubiquitin-like modifier activating enzyme 6
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)
WNT10B wingless-type MMTV integration site family, member 10B
WSCD1 WSC domain containing 1
YBX3 Y box binding protein 3
ZNF37BP zinc finger protein 37B, pseudogene
ZNF862 zinc finger protein 862

decreased expression

Symbol Name
ACTG2 actin, gamma 2, smooth muscle, enteric
ACTL8 actin-like 8
ADM adrenomedullin
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
APLP1 amyloid beta (A4) precursor-like protein 1
ARID3B AT rich interactive domain 3B (BRIGHT-like)
BAHCC1 BAH domain and coiled-coil containing 1
BLNK B-cell linker
BMP10 bone morphogenetic protein 10
C11ORF63 chromosome 11 open reading frame 63
C1ORF159 chromosome 1 open reading frame 159
C22ORF46 chromosome 22 open reading frame 46
C7ORF43 chromosome 7 open reading frame 43
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CALML5 calmodulin-like 5
CCDC68 coiled-coil domain containing 68
CCDC71 coiled-coil domain containing 71
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CFAP70 cilia and flagella associated protein 70
CHKB choline kinase beta
CHRM3 cholinergic receptor, muscarinic 3
CLCN2 chloride channel, voltage-sensitive 2
CLDN1 claudin 1
CLSPN claspin
CLSTN2 calsyntenin 2
CNTFR ciliary neurotrophic factor receptor
CRIP1 cysteine-rich protein 1 (intestinal)
DENND4A DENN/MADD domain containing 4A
DNAL4 dynein, axonemal, light chain 4
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DYSF dysferlin
EGFL7 EGF-like-domain, multiple 7
EPB41L5 erythrocyte membrane protein band 4.1 like 5
ERMAP erythroblast membrane-associated protein (Scianna blood group)
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM184A family with sequence similarity 184, member A
FAM212B family with sequence similarity 212, member B
FAM46C family with sequence similarity 46, member C
FBXL7 F-box and leucine-rich repeat protein 7
FBXO22 F-box protein 22
GNG7 guanine nucleotide binding protein (G protein), gamma 7
HIST1H1D histone cluster 1, H1d
HIST1H1E histone cluster 1, H1e
HIST2H2AA3 histone cluster 2, H2aa3
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HOXA4 homeobox A4
HOXB2 homeobox B2
HOXC5 homeobox C5
HOXC8 homeobox C8
IL12RB1 interleukin 12 receptor, beta 1
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
KLF3 Kruppel-like factor 3 (basic)
KPNA5 karyopherin alpha 5 (importin alpha 6)
KRT15 keratin 15, type I
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LIN7B lin-7 homolog B (C. elegans)
LONRF3 LON peptidase N-terminal domain and ring finger 3
MBTD1 mbt domain containing 1
MCOLN1 mucolipin 1
MMP9 matrix metallopeptidase 9
MOB3B MOB kinase activator 3B
NCALD neurocalcin delta
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NKAIN1 Na+/K+ transporting ATPase interacting 1
NYNRIN NYN domain and retroviral integrase containing
PLA2G3 phospholipase A2, group III
PLCD1 phospholipase C, delta 1
PLEKHA6 pleckstrin homology domain containing, family A member 6
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRR4 proline rich 4 (lacrimal)
RAB36 RAB36, member RAS oncogene family
RAD54L2 RAD54-like 2 (S. cerevisiae)
RCAN3 RCAN family member 3
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RPAP1 RNA polymerase II associated protein 1
RPL10L ribosomal protein L10-like
RPS14P3 ribosomal protein S14 pseudogene 3
SLC25A40 solute carrier family 25, member 40
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SLPI secretory leukocyte peptidase inhibitor
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TARP TCR gamma alternate reading frame protein
TBC1D19 TBC1 domain family, member 19
TLR2 toll-like receptor 2
TMEM158 transmembrane protein 158 (gene/pseudogene)
TNS2 tensin 2
TOM1 target of myb1 (chicken)
TRPV6 transient receptor potential cation channel, subfamily V, member 6
UBQLN4 ubiquilin 4
UNC13B unc-13 homolog B (C. elegans)
UNC93B1 unc-93 homolog B1 (C. elegans)
VIM vimentin
XDH xanthine dehydrogenase
ZC3H3 zinc finger CCCH-type containing 3
ZDHHC11 zinc finger, DHHC-type containing 11
ZNF484 zinc finger protein 484
ZNF552 zinc finger protein 552
ZSCAN2 zinc finger and SCAN domain containing 2