bromperidol-7457 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the bromperidol-7457 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADORA1 adenosine A1 receptor
AIM1L absent in melanoma 1-like
ALDH7A1 aldehyde dehydrogenase 7 family, member A1
ANP32A-IT1 ANP32A intronic transcript 1
APOC1 apolipoprotein C-I
ARTN artemin
ASIC1 acid sensing (proton gated) ion channel 1
ATF3 activating transcription factor 3
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BFSP1 beaded filament structural protein 1, filensin
BMP5 bone morphogenetic protein 5
C19ORF73 chromosome 19 open reading frame 73
CBX7 chromobox homolog 7
CC2D1A coiled-coil and C2 domain containing 1A
CD53 CD53 molecule
CELSR3 cadherin, EGF LAG seven-pass G-type receptor 3
CNTN1 contactin 1
CNTNAP2 contactin associated protein-like 2
CPT1A carnitine palmitoyltransferase 1A (liver)
CSF1R colony stimulating factor 1 receptor
CST6 cystatin E/M
CTAGE5 CTAGE family, member 5
DDIT4 DNA-damage-inducible transcript 4
DIO2 deiodinase, iodothyronine, type II
DNASE1L3 deoxyribonuclease I-like 3
DSG3 desmoglein 3
DST dystonin
EFNB3 ephrin-B3
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
ETV6 ets variant 6
FAM204A family with sequence similarity 204, member A
FGF4 fibroblast growth factor 4
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5
GM2A GM2 ganglioside activator
GPR137 G protein-coupled receptor 137
GRSF1 G-rich RNA sequence binding factor 1
GSTCD glutathione S-transferase, C-terminal domain containing
HIST1H1B histone cluster 1, H1b
HMHA1 histocompatibility (minor) HA-1
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IGFBP3 insulin-like growth factor binding protein 3
INHBA inhibin, beta A
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KHSRP KH-type splicing regulatory protein
KRT17 keratin 17, type I
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LOC644450 uncharacterized LOC644450
LPIN1 lipin 1
LRRC15 leucine rich repeat containing 15
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MBNL2 muscleblind-like splicing regulator 2
MBOAT7 membrane bound O-acyltransferase domain containing 7
MFAP3L microfibrillar-associated protein 3-like
MGEA5 meningioma expressed antigen 5 (hyaluronidase)
MIIP migration and invasion inhibitory protein
MVK mevalonate kinase
NF1 neurofibromin 1
NME5 NME/NM23 family member 5
NMT1 N-myristoyltransferase 1
NOX5 NADPH oxidase, EF-hand calcium binding domain 5
NR6A1 nuclear receptor subfamily 6, group A, member 1
NRSN2 neurensin 2
OLFML2B olfactomedin-like 2B
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
OSGIN1 oxidative stress induced growth inhibitor 1
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PLA2G3 phospholipase A2, group III
PLK4 polo-like kinase 4
PLXNB1 plexin B1
POLH polymerase (DNA directed), eta
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PTGES prostaglandin E synthase
PTP4A3 protein tyrosine phosphatase type IVA, member 3
RAB40C RAB40C, member RAS oncogene family
RND2 Rho family GTPase 2
RNF24 ring finger protein 24
RPL35A ribosomal protein L35a
RSL1D1 ribosomal L1 domain containing 1
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
SAT1 spermidine/spermine N1-acetyltransferase 1
SCAPER S-phase cyclin A-associated protein in the ER
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SOCS6 suppressor of cytokine signaling 6
STIM1 stromal interaction molecule 1
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TMEM63A transmembrane protein 63A
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TRIM2 tripartite motif containing 2
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TTC38 tetratricopeptide repeat domain 38
VEGFB vascular endothelial growth factor B
WDR25 WD repeat domain 25
WSB1 WD repeat and SOCS box containing 1
ZBED1 zinc finger, BED-type containing 1
ZNF484 zinc finger protein 484
ZNF821 zinc finger protein 821

decreased expression

Symbol Name
AEN apoptosis enhancing nuclease
ANKEF1 ankyrin repeat and EF-hand domain containing 1
ANKRD36 ankyrin repeat domain 36
ARHGAP11A Rho GTPase activating protein 11A
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ATP13A2 ATPase type 13A2
BTBD2 BTB (POZ) domain containing 2
BTF3P12 basic transcription factor 3 pseudogene 12
C17ORF70 chromosome 17 open reading frame 70
C21ORF91 chromosome 21 open reading frame 91
C2CD2 C2 calcium-dependent domain containing 2
C7ORF43 chromosome 7 open reading frame 43
CCDC88C coiled-coil domain containing 88C
CDK3 cyclin-dependent kinase 3
CHML choroideremia-like (Rab escort protein 2)
CHMP7 charged multivesicular body protein 7
CIC capicua transcriptional repressor
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CNPY3 canopy FGF signaling regulator 3
CYR61 cysteine-rich, angiogenic inducer, 61
DCAF13 DDB1 and CUL4 associated factor 13
DEAF1 DEAF1 transcription factor
DGKE diacylglycerol kinase, epsilon 64kDa
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EPHA2 EPH receptor A2
FAM155B family with sequence similarity 155, member B
FCHO1 FCH domain only 1
FKBP10 FK506 binding protein 10, 65 kDa
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2
GALT galactose-1-phosphate uridylyltransferase
GAREM GRB2 associated, regulator of MAPK1
GPR27 G protein-coupled receptor 27
GRWD1 glutamate-rich WD repeat containing 1
HDAC4 histone deacetylase 4
HIRIP3 HIRA interacting protein 3
HIST1H2AG histone cluster 1, H2ag
HIST1H4F histone cluster 1, H4f
HRAS Harvey rat sarcoma viral oncogene homolog
IFT22 intraflagellar transport 22
IMPACT impact RWD domain protein
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
IRF2BP1 interferon regulatory factor 2 binding protein 1
KDM5C lysine (K)-specific demethylase 5C
KNTC1 kinetochore associated 1
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LINC00339 long intergenic non-protein coding RNA 339
LRRC61 leucine rich repeat containing 61
MANBA mannosidase, beta A, lysosomal
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAPKBP1 mitogen-activated protein kinase binding protein 1
MEIS1 Meis homeobox 1
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MSL1 male-specific lethal 1 homolog (Drosophila)
MT1HL1 metallothionein 1H-like 1
MTRF1 mitochondrial translational release factor 1
MUM1 melanoma associated antigen (mutated) 1
MXD3 MAX dimerization protein 3
N6AMT1 N-6 adenine-specific DNA methyltransferase 1 (putative)
NDRG4 NDRG family member 4
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PC pyruvate carboxylase
PLA2G10 phospholipase A2, group X
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
RANGRF RAN guanine nucleotide release factor
RBL1 retinoblastoma-like 1
RFTN1 raftlin, lipid raft linker 1
RPL23AP32 ribosomal protein L23a pseudogene 32
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SIK1 salt-inducible kinase 1
SKA1 spindle and kinetochore associated complex subunit 1
SLC16A6 solute carrier family 16, member 6
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SNRPC small nuclear ribonucleoprotein polypeptide C
STAG3L1 stromal antigen 3-like 1 (pseudogene)
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
THNSL1 threonine synthase-like 1 (S. cerevisiae)
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast)
TMEM110 transmembrane protein 110
TRAF5 TNF receptor-associated factor 5
TRIM52 tripartite motif containing 52
TRNAU1AP tRNA selenocysteine 1 associated protein 1
TSPAN1 tetraspanin 1
TSR2 TSR2, 20S rRNA accumulation, homolog (S. cerevisiae)
TUBA3D tubulin, alpha 3d
UBIAD1 UbiA prenyltransferase domain containing 1
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
XAB2 XPA binding protein 2
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
ZMAT5 zinc finger, matrin-type 5
ZNF701 zinc finger protein 701
ZNHIT2 zinc finger, HIT-type containing 2
ZW10 zw10 kinetochore protein