brompheniramine-1335 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the brompheniramine-1335 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ADAM15 ADAM metallopeptidase domain 15
AEN apoptosis enhancing nuclease
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ANKRD12 ankyrin repeat domain 12
ARFRP1 ADP-ribosylation factor related protein 1
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ATP13A2 ATPase type 13A2
ATP5SL ATP5S-like
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1
BCAP29 B-cell receptor-associated protein 29
BTN3A1 butyrophilin, subfamily 3, member A1
C5ORF45 chromosome 5 open reading frame 45
CCDC106 coiled-coil domain containing 106
CD6 CD6 molecule
CLEC4A C-type lectin domain family 4, member A
CLN8 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
CORO7 coronin 7
CPT1A carnitine palmitoyltransferase 1A (liver)
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
DUS2 dihydrouridine synthase 2
E2F4 E2F transcription factor 4, p107/p130-binding
EML3 echinoderm microtubule associated protein like 3
ENO3 enolase 3 (beta, muscle)
ERN2 endoplasmic reticulum to nucleus signaling 2
EXOC7 exocyst complex component 7
FAM3A family with sequence similarity 3, member A
FGL2 fibrinogen-like 2
FKBP15 FK506 binding protein 15, 133kDa
FOSL2 FOS-like antigen 2
G6PC3 glucose 6 phosphatase, catalytic, 3
GAR1 GAR1 ribonucleoprotein
GPR21 G protein-coupled receptor 21
GPSM3 G-protein signaling modulator 3
HCAR3 hydroxycarboxylic acid receptor 3
HDAC7 histone deacetylase 7
HEMK1 HemK methyltransferase family member 1
HOMER3 homer scaffolding protein 3
HSF1 heat shock transcription factor 1
ICAM2 intercellular adhesion molecule 2
IFITM3 interferon induced transmembrane protein 3
INO80D INO80 complex subunit D
INPP5D inositol polyphosphate-5-phosphatase, 145kDa
KCNK5 potassium channel, two pore domain subfamily K, member 5
LDB1 LIM domain binding 1
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LOC390998 ribosomal protein L10 pseudogene
LPAR1 lysophosphatidic acid receptor 1
LRRC1 leucine rich repeat containing 1
MAN1C1 mannosidase, alpha, class 1C, member 1
MAP2K7 mitogen-activated protein kinase kinase 7
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
NDE1 nudE neurodevelopment protein 1
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NRP2 neuropilin 2
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
OGFR opioid growth factor receptor
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PCGF3 polycomb group ring finger 3
PDLIM7 PDZ and LIM domain 7 (enigma)
PEX10 peroxisomal biogenesis factor 10
PEX6 peroxisomal biogenesis factor 6
PLCB4 phospholipase C, beta 4
PMS2P2 postmeiotic segregation increased 2 pseudogene 2
POFUT1 protein O-fucosyltransferase 1
POU3F1 POU class 3 homeobox 1
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2)
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PYGB phosphorylase, glycogen; brain
QTRT1 queuine tRNA-ribosyltransferase 1
RASA3 RAS p21 protein activator 3
RBM42 RNA binding motif protein 42
RIN3 Ras and Rab interactor 3
RPL13P5 ribosomal protein L13 pseudogene 5
RPL18 ribosomal protein L18
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
RXRB retinoid X receptor, beta
SAPCD1 suppressor APC domain containing 1
SCN10A sodium channel, voltage gated, type X alpha subunit
SGSM2 small G protein signaling modulator 2
SLC12A9 solute carrier family 12, member 9
SLC30A5 solute carrier family 30 (zinc transporter), member 5
SLC35C2 solute carrier family 35 (GDP-fucose transporter), member C2
STEAP3 STEAP family member 3, metalloreductase
STXBP6 syntaxin binding protein 6 (amisyn)
TAPBP TAP binding protein (tapasin)
TMEM159 transmembrane protein 159
TMEM209 transmembrane protein 209
TRAPPC9 trafficking protein particle complex 9
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
VEGFA vascular endothelial growth factor A
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZNF37BP zinc finger protein 37B, pseudogene
ZNF609 zinc finger protein 609
ZNF667 zinc finger protein 667

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2
ANKRD40 ankyrin repeat domain 40
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
ASTE1 asteroid homolog 1 (Drosophila)
C11ORF71 chromosome 11 open reading frame 71
C21ORF91 chromosome 21 open reading frame 91
C7ORF43 chromosome 7 open reading frame 43
CCRL2 chemokine (C-C motif) receptor-like 2
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CD151 CD151 molecule (Raph blood group)
CDIP1 cell death-inducing p53 target 1
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
ECI2 enoyl-CoA delta isomerase 2
EGR3 early growth response 3
ELP3 elongator acetyltransferase complex subunit 3
ELP6 elongator acetyltransferase complex subunit 6
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
ERAP2 endoplasmic reticulum aminopeptidase 2
EXD2 exonuclease 3'-5' domain containing 2
EXOC5 exocyst complex component 5
FAM173A family with sequence similarity 173, member A
FAM57A family with sequence similarity 57, member A
FHIT fragile histidine triad
FKTN fukutin
GALT galactose-1-phosphate uridylyltransferase
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C
GIN1 gypsy retrotransposon integrase 1
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GPR63 G protein-coupled receptor 63
GTF2IRD1 GTF2I repeat domain containing 1
HIST1H1E histone cluster 1, H1e
HIST1H2BH histone cluster 1, H2bh
HIST1H4J histone cluster 1, H4j
HPS6 Hermansky-Pudlak syndrome 6
HRAS Harvey rat sarcoma viral oncogene homolog
HYMAI hydatidiform mole associated and imprinted (non-protein coding)
IGFLR1 IGF-like family receptor 1
KDM5C lysine (K)-specific demethylase 5C
LHFP lipoma HMGIC fusion partner
LRRC37A2 leucine rich repeat containing 37, member A2
LRRC42 leucine rich repeat containing 42
LRRK1 leucine-rich repeat kinase 1
MDM4 MDM4, p53 regulator
MNAT1 MNAT CDK-activating kinase assembly factor 1
MTRF1 mitochondrial translational release factor 1
MYL5 myosin, light chain 5, regulatory
N4BP2L2-IT2 N4BPL2 intronic transcript 2
NARFL nuclear prelamin A recognition factor-like
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
NPIPB15 nuclear pore complex interacting protein family, member B15
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2
PARP16 poly (ADP-ribose) polymerase family, member 16
PDLIM2 PDZ and LIM domain 2 (mystique)
PEX13 peroxisomal biogenesis factor 13
PEX26 peroxisomal biogenesis factor 26
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLA2G15 phospholipase A2, group XV
PMM1 phosphomannomutase 1
PYCR1 pyrroline-5-carboxylate reductase 1
RAB17 RAB17, member RAS oncogene family
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RNF121 ring finger protein 121
RNF122 ring finger protein 122
RNF220 ring finger protein 220
S1PR4 sphingosine-1-phosphate receptor 4
SAMD9 sterile alpha motif domain containing 9
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22
SLC35E3 solute carrier family 35, member E3
SNAP29 synaptosomal-associated protein, 29kDa
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STIM1 stromal interaction molecule 1
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TCTN2 tectonic family member 2
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
THBS3 thrombospondin 3
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMOD3 tropomodulin 3 (ubiquitous)
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TOR4A torsin family 4, member A
TRIM26 tripartite motif containing 26
TRIM52 tripartite motif containing 52
TRPS1 trichorhinophalangeal syndrome I
TTC33 tetratricopeptide repeat domain 33
TTPAL tocopherol (alpha) transfer protein-like
TUBA3C tubulin, alpha 3c
USB1 U6 snRNA biogenesis 1
ZMAT5 zinc finger, matrin-type 5
ZNF304 zinc finger protein 304
ZNF324 zinc finger protein 324
ZNF536 zinc finger protein 536
ZNF552 zinc finger protein 552
ZNF747 zinc finger protein 747
ZNF787 zinc finger protein 787
ZW10 zw10 kinetochore protein