bronchiolitis obliterans Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
Description A obstructive lung disease involving obstruction of the bronchioles due to inflammation and fibrosis which occurs as a complication of various lung conditions or physiological insults. (Human Disease Ontology, DOID_2799)
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Genes

136 genes co-occuring with the disease bronchiolitis obliterans in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
GOSR2 golgi SNAP receptor complex member 2 1.52688
CABIN1 calcineurin binding protein 1 1.34199
PPL periplakin 1.30794
CD4 CD4 molecule 1.21782
HLA-C major histocompatibility complex, class I, C 1.17851
TUBA1B tubulin, alpha 1b 1.14305
TGFB1 transforming growth factor, beta 1 1.10846
CXCL8 chemokine (C-X-C motif) ligand 8 1.06186
ZNF33A zinc finger protein 33A 0.978848
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 0.964567
OAZ1 ornithine decarboxylase antizyme 1 0.957868
HLA-A major histocompatibility complex, class I, A 0.922149
DSG3 desmoglein 3 0.882701
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) 0.824128
EVPL envoplakin 0.804436
IL17A interleukin 17A 0.804026
ICOS inducible T-cell co-stimulator 0.781479
DSP desmoplakin 0.78066
HLA-B major histocompatibility complex, class I, B 0.777795
CXCR3 chemokine (C-X-C motif) receptor 3 0.771661
CXCL10 chemokine (C-X-C motif) ligand 10 0.767985
CAPS calcyphosine 0.738271
MMP7 matrix metallopeptidase 7 0.736649
MMP9 matrix metallopeptidase 9 0.722886
TNF tumor necrosis factor 0.722077
CXCL9 chemokine (C-X-C motif) ligand 9 0.715618
CCL2 chemokine (C-C motif) ligand 2 0.703938
LARS leucyl-tRNA synthetase 0.698313
SLPI secretory leukocyte peptidase inhibitor 0.686691
IL10 interleukin 10 0.674315
CXCL11 chemokine (C-X-C motif) ligand 11 0.674315
FOXP3 forkhead box P3 0.669936
SHE Src homology 2 domain containing E 0.666755
CCR2 chemokine (C-C motif) receptor 2 0.666755
DSG1 desmoglein 1 0.654463
EDA ectodysplasin A 0.651694
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) 0.646953
SMAD3 SMAD family member 3 0.646165
OPTN optineurin 0.641039
TEK TEK tyrosine kinase, endothelial 0.640251
LPIN3 lipin 3 0.622575
MMP8 matrix metallopeptidase 8 0.607714
PSMC4 proteasome (prosome, macropain) 26S subunit, ATPase, 4 0.60225
CXCR2 chemokine (C-X-C motif) receptor 2 0.598351
IL2 interleukin 2 0.593674
TIMP1 TIMP metallopeptidase inhibitor 1 0.565666
ELANE elastase, neutrophil expressed 0.558674
CDAN1 codanin 1 0.552075
EDN1 endothelin 1 0.550134
SFTPB surfactant protein B 0.518805
MUC1 mucin 1, cell surface associated 0.51842
KLK8 kallikrein-related peptidase 8 0.501527
SFTPD surfactant protein D 0.500379
AZU1 azurocidin 1 0.485505
MRPL49 mitochondrial ribosomal protein L49 0.484364
BDKRB1 bradykinin receptor B1 0.482844
MPO myeloperoxidase 0.477151
CAV2 caveolin 2 0.465794
NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) 0.457109
HMOX1 heme oxygenase 1 0.453339
PDGFB platelet-derived growth factor beta polypeptide 0.449194
BDKRB2 bradykinin receptor B2 0.434148
RAG1 recombination activating gene 1 0.433772
VPS11 vacuolar protein sorting 11 homolog (S. cerevisiae) 0.427015
MICA MHC class I polypeptide-related sequence A 0.414276
IL1B interleukin 1, beta 0.407919
CD79A CD79a molecule, immunoglobulin-associated alpha 0.407919
S100A4 S100 calcium binding protein A4 0.402318
IL2RA interleukin 2 receptor, alpha 0.398216
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 0.397843
TNC tenascin C 0.394863
SAA4 serum amyloid A4, constitutive 0.391141
S100A8 S100 calcium binding protein A8 0.390397
SLC35E2B solute carrier family 35, member E2B 0.381852
CD40LG CD40 ligand 0.379997
VASH1 vasohibin 1 0.372217
IL6 interleukin 6 0.371847
ABCE1 ATP-binding cassette, sub-family E (OABP), member 1 0.358183
EPCAM epithelial cell adhesion molecule 0.356341
MMP2 matrix metallopeptidase 2 0.35082
CLEC11A C-type lectin domain family 11, member A 0.350084
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.349349
ADORA2A adenosine A2a receptor 0.33944
IDO1 indoleamine 2,3-dioxygenase 1 0.337975
MT1A metallothionein 1A 0.334315
CTGF connective tissue growth factor 0.327375
MYO1G myosin IG 0.32701
FGF2 fibroblast growth factor 2 (basic) 0.325916
BPIFA1 BPI fold containing family A, member 1 0.31029
CD19 CD19 molecule 0.309928
RNASE3 ribonuclease, RNase A family, 3 0.301254
FTL ferritin, light polypeptide 0.300533
FTH1 ferritin, heavy polypeptide 1 0.300173
PRF1 perforin 1 (pore forming protein) 0.298731
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.292616
ICOSLG inducible T-cell co-stimulator ligand 0.283655
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1 0.282225
TLR10 toll-like receptor 10 0.271886
FOXF1 forkhead box F1 0.270108
SOX18 SRY (sex determining region Y)-box 18 0.26514
PLCH2 phospholipase C, eta 2 0.263722
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) 0.25877
FN1 fibronectin 1 0.254183
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 0.249257
FLNC filamin C, gamma 0.248554
CRP C-reactive protein, pentraxin-related 0.246799
TGFBR3 transforming growth factor, beta receptor III 0.246098
CCL5 chemokine (C-C motif) ligand 5 0.245046
SEMA6C sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C 0.238054
CAND2 cullin-associated and neddylation-dissociated 2 (putative) 0.230755
GJB6 gap junction protein, beta 6, 30kDa 0.230409
CCL22 chemokine (C-C motif) ligand 22 0.230063
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 0.227642
ICAM1 intercellular adhesion molecule 1 0.222479
CD86 CD86 molecule 0.22145
CD68 CD68 molecule 0.207245
CCL26 chemokine (C-C motif) ligand 26 0.202946
LTA4H leukotriene A4 hydrolase 0.200006
HARS histidyl-tRNA synthetase 0.194232
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 0.191408
CCL20 chemokine (C-C motif) ligand 20 0.190168
CCL13 chemokine (C-C motif) ligand 13 0.187415
KRT14 keratin 14, type I 0.18591
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 0.184424
HBA2 hemoglobin, alpha 2 0.184128
LXN latexin 0.175947
IL7R interleukin 7 receptor 0.174093
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.173057
FGF9 fibroblast growth factor 9 0.170054
REXO1L1P REX1, RNA exonuclease 1 homolog (S. cerevisiae)-like 1, pseudogene 0.169812
CCL17 chemokine (C-C motif) ligand 17 0.166995
MMP12 matrix metallopeptidase 12 0.165435
HBEGF heparin-binding EGF-like growth factor 0.163111
TIMP2 TIMP metallopeptidase inhibitor 2 0.162908
PDGFA platelet-derived growth factor alpha polypeptide 0.161523
IL16 interleukin 16 0.159658