bronchiolitis Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
Description A lung disease that is an inflammation of the bronchioles, the smallest air passages of the lungs. It is caused by viruses and bacteria. The disease has_symptom cough, has_symptom wheezing, has_symptom shortness of breath, has_symptom fever, has_symptom nasal flaring in infants and has_symptom bluish skin due to lack of oxygen. (Human Disease Ontology, DOID_2942)
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Genes

163 genes co-occuring with the disease bronchiolitis in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
RNASE3 ribonuclease, RNase A family, 3 1.37556
FAM102A family with sequence similarity 102, member A 1.31799
CXCL8 chemokine (C-X-C motif) ligand 8 1.18066
CCL3 chemokine (C-C motif) ligand 3 1.17636
NPW neuropeptide W 1.16179
TLR4 toll-like receptor 4 1.04462
CD4 CD4 molecule 1.04167
CAV2 caveolin 2 1.03535
IFNA5 interferon, alpha 5 1.00668
CD79A CD79a molecule, immunoglobulin-associated alpha 0.997392
ZNF83 zinc finger protein 83 0.980952
IL4 interleukin 4 0.957868
ZNF17 zinc finger protein 17 0.952856
MS4A2 membrane-spanning 4-domains, subfamily A, member 2 0.938289
IL9 interleukin 9 0.892129
TLR10 toll-like receptor 10 0.879424
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) 0.878195
PI3 peptidase inhibitor 3, skin-derived 0.868777
FAM21C family with sequence similarity 21, member C 0.838066
CXCL10 chemokine (C-X-C motif) ligand 10 0.830279
CRP C-reactive protein, pentraxin-related 0.830279
BET1 Bet1 golgi vesicular membrane trafficking protein 0.813873
TNF tumor necrosis factor 0.799923
ICAM1 intercellular adhesion molecule 1 0.773296
IFNL2 interferon, lambda 2 0.759416
DHPS deoxyhypusine synthase 0.755342
IMPACT impact RWD domain protein 0.753713
MAVS mitochondrial antiviral signaling protein 0.752085
IFI27 interferon, alpha-inducible protein 27 0.741111
OR4F29 olfactory receptor, family 4, subfamily F, member 29 0.739488
CCL2 chemokine (C-C motif) ligand 2 0.716021
STMN3 stathmin-like 3 0.708364
IFNG interferon, gamma 0.699517
TLR1 toll-like receptor 1 0.683892
IL4R interleukin 4 receptor 0.683093
EDC3 enhancer of mRNA decapping 3 0.674713
TLR6 toll-like receptor 6 0.657234
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 0.642221
CCL5 chemokine (C-C motif) ligand 5 0.633956
RASSF6 Ras association (RalGDS/AF-6) domain family member 6 0.625319
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 0.605762
SFTPA1 surfactant protein A1 0.605372
IFNL1 interferon, lambda 1 0.590169
CECR1 cat eye syndrome chromosome region, candidate 1 0.58433
PDE4C phosphodiesterase 4C, cAMP-specific 0.577716
ETFA electron-transfer-flavoprotein, alpha polypeptide 0.577327
IRF7 interferon regulatory factor 7 0.57305
IFNA13 interferon, alpha 13 0.572662
CLNK cytokine-dependent hematopoietic cell linker 0.563335
TLR3 toll-like receptor 3 0.554403
OPRD1 opioid receptor, delta 1 0.547807
TLR2 toll-like receptor 2 0.531541
MPO myeloperoxidase 0.530381
STAT1 signal transducer and activator of transcription 1, 91kDa 0.523045
CXCL11 chemokine (C-X-C motif) ligand 11 0.520346
BDKRB1 bradykinin receptor B1 0.51919
CXCR2 chemokine (C-X-C motif) receptor 2 0.508424
IL6 interleukin 6 0.50689
IL10 interleukin 10 0.491215
TLR7 toll-like receptor 7 0.48893
USF2 upstream transcription factor 2, c-fos interacting 0.48893
CLCA1 chloride channel accessory 1 0.485505
CLC Charcot-Leyden crystal galectin 0.485125
RNF19B ring finger protein 19B 0.475255
POU2F1 POU class 2 homeobox 1 0.46466
IL13 interleukin 13 0.461639
STAT2 signal transducer and activator of transcription 2, 113kDa 0.459751
TAC1 tachykinin, precursor 1 0.444676
KRTAP1-3 keratin associated protein 1-3 0.436402
KRTAP1-1 keratin associated protein 1-1 0.436402
SELL selectin L 0.43227
CX3CR1 chemokine (C-X3-C motif) receptor 1 0.42589
ICOS inducible T-cell co-stimulator 0.42589
NEUROD1 neuronal differentiation 1 0.420266
PER1 period circadian clock 1 0.418768
ARR3 arrestin 3, retinal (X-arrestin) 0.412405
BATF2 basic leucine zipper transcription factor, ATF-like 2 0.407172
CCL8 chemokine (C-C motif) ligand 8 0.407172
IRF1 interferon regulatory factor 1 0.404557
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.403811
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 0.377402
TIMP1 TIMP metallopeptidase inhibitor 1 0.377402
BIN2 bridging integrator 2 0.376661
ABCE1 ATP-binding cassette, sub-family E (OABP), member 1 0.376661
MX1 MX dynamin-like GTPase 1 0.371847
SFTPB surfactant protein B 0.360395
SLC25A18 solute carrier family 25 (glutamate carrier), member 18 0.358551
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.358183
IL5 interleukin 5 0.357814
TCEB1 transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C) 0.354131
MACF1 microtubule-actin crosslinking factor 1 0.350084
ARG1 arginase 1 0.346409
SFTPA2 surfactant protein A2 0.342372
ELANE elastase, neutrophil expressed 0.337242
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide 0.334315
CUL2 cullin 2 0.333583
AVP arginine vasopressin 0.332487
PHF1 PHD finger protein 1 0.331391
CXCL9 chemokine (C-X-C motif) ligand 9 0.331025
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.32993
TGFB1 transforming growth factor, beta 1 0.329565
IFNA1 interferon, alpha 1 0.325916
CCR7 chemokine (C-C motif) receptor 7 0.321181
IL17C interleukin 17C 0.32009
ALYREF Aly/REF export factor 0.315729
SFTPC surfactant protein C 0.313552
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.313552
HRC histidine rich calcium binding protein 0.310652
PGM3 phosphoglucomutase 3 0.310652
PRF1 perforin 1 (pore forming protein) 0.30848
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific) 0.306672
NMS neuromedin S 0.30631
TLR5 toll-like receptor 5 0.299092
CMKLR1 chemerin chemokine-like receptor 1 0.286519
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 0.28151
IRF3 interferon regulatory factor 3 0.27794
HBA2 hemoglobin, alpha 2 0.276514
TMEFF2 transmembrane protein with EGF-like and two follistatin-like domains 2 0.275445
SIX6 SIX homeobox 6 0.274732
CXCR3 chemokine (C-X-C motif) receptor 3 0.262306
MUC5B mucin 5B, oligomeric mucus/gel-forming 0.254888
ACAP3 ArfGAP with coiled-coil, ankyrin repeat and PH domains 3 0.254888
MUC1 mucin 1, cell surface associated 0.253127
IL17A interleukin 17A 0.252422
IL1B interleukin 1, beta 0.250663
G6PC3 glucose 6 phosphatase, catalytic, 3 0.24996
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor 0.24715
IL33R interleukin 33 receptor 0.246799
SDCBP syndecan binding protein (syntenin) 0.245396
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 0.244696
CAV1 caveolin 1, caveolae protein, 22kDa 0.243645
CXCL3 chemokine (C-X-C motif) ligand 3 0.23945
IL18 interleukin 18 0.239101
ALB albumin 0.239101
PDE4B phosphodiesterase 4B, cAMP-specific 0.227297
IL2 interleukin 2 0.225917
CCL11 chemokine (C-C motif) ligand 11 0.225573
TACR1 tachykinin receptor 1 0.225573
FANCB Fanconi anemia, complementation group B 0.224196
CARD17 caspase recruitment domain family, member 17 0.214636
IRF2 interferon regulatory factor 2 0.214297
TNFRSF25 tumor necrosis factor receptor superfamily, member 25 0.210589
PPP1R14A protein phosphatase 1, regulatory (inhibitor) subunit 14A 0.208914
IFNL3 interferon, lambda 3 0.208245
CD40LG CD40 ligand 0.205585
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta 0.199681
ISG20 interferon stimulated exonuclease gene 20kDa 0.196779
IL1A interleukin 1, alpha 0.192657
B4GALNT2 beta-1,4-N-acetyl-galactosaminyl transferase 2 0.184424
CIITA class II, major histocompatibility complex, transactivator 0.182086
PDE4A phosphodiesterase 4A, cAMP-specific 0.181222
GRHL1 grainyhead-like 1 (Drosophila) 0.180367
HHAT hedgehog acyltransferase 0.179802
MX2 MX dynamin-like GTPase 2 0.179802
PYCR1 pyrroline-5-carboxylate reductase 1 0.17952
IFIH1 interferon induced with helicase C domain 1 0.175679
PPARGC1B peroxisome proliferator-activated receptor gamma, coactivator 1 beta 0.175146
MMP9 matrix metallopeptidase 9 0.174354
GAA glucosidase, alpha; acid 0.174093
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 0.164571
ADRBK1 adrenergic, beta, receptor kinase 1 0.164571
FPR1 formyl peptide receptor 1 0.163111
LTF lactotransferrin 0.162306