bronchitis Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
Description A bronchial disease that is an inflammation of the bronchial tubes. It is caused by bacteria and viruses. The disease has_symptom cough with mucus, has_symptom shortness of breath, has_symptom low fever and has_symptom chest tightness. (Human Disease Ontology, DOID_6132)
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Genes

264 genes co-occuring with the disease bronchitis in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
CD79A CD79a molecule, immunoglobulin-associated alpha 1.61978
ELANE elastase, neutrophil expressed 1.48472
CRP C-reactive protein, pentraxin-related 1.40789
CXCL8 chemokine (C-X-C motif) ligand 8 1.35115
ALB albumin 1.34025
PDZD11 PDZ domain containing 11 1.30401
HSF4 heat shock transcription factor 4 1.28261
MUC5B mucin 5B, oligomeric mucus/gel-forming 1.27388
MS4A2 membrane-spanning 4-domains, subfamily A, member 2 1.25167
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 1.24732
RNASE3 ribonuclease, RNase A family, 3 1.21132
HTRA3 HtrA serine peptidase 3 1.17421
MPO myeloperoxidase 1.1312
CD4 CD4 molecule 1.1051
SLPI secretory leukocyte peptidase inhibitor 1.06228
KSR1 kinase suppressor of ras 1 1.0442
TNF tumor necrosis factor 1.04377
TAC1 tachykinin, precursor 1 1.01174
PDE4A phosphodiesterase 4A, cAMP-specific 0.997814
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 0.99697
LYZ lysozyme 0.989379
NPW neuropeptide W 0.926279
ICAM1 intercellular adhesion molecule 1 0.876557
TOB1 transducer of ERBB2, 1 0.824948
LTF lactotransferrin 0.808539
CXCL10 chemokine (C-X-C motif) ligand 10 0.808129
SHF Src homology 2 domain containing F 0.804026
IL5 interleukin 5 0.785165
NADK NAD kinase 0.785165
IL1B interleukin 1, beta 0.781479
ACE angiotensin I converting enzyme 0.779023
FLNC filamin C, gamma 0.769618
MMP12 matrix metallopeptidase 12 0.752085
DNAAF2 dynein, axonemal, assembly factor 2 0.72612
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 0.723694
TACR1 tachykinin receptor 1 0.714408
NPS neuropeptide S 0.697109
MYO5C myosin VC 0.695905
NEUROD1 neuronal differentiation 1 0.668742
VIP vasoactive intestinal peptide 0.66596
DEFB104B defensin, beta 104B 0.665166
MARCKS myristoylated alanine-rich protein kinase C substrate 0.662784
CAT catalase 0.662387
CTSG cathepsin G 0.661197
PSG6 pregnancy specific beta-1-glycoprotein 6 0.647743
IL6 interleukin 6 0.637889
IL4 interleukin 4 0.636315
OR13H1 olfactory receptor, family 13, subfamily H, member 1 0.634349
EPCAM epithelial cell adhesion molecule 0.622183
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) 0.620226
GSTM1 glutathione S-transferase mu 1 0.612792
FAM21C family with sequence similarity 21, member C 0.612401
CDSN corneodesmosin 0.612011
TLR4 toll-like receptor 4 0.607323
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 0.594843
EHF ets homologous factor 0.583163
CCL3 chemokine (C-C motif) ligand 3 0.581606
SLC25A29 solute carrier family 25 (mitochondrial carnitine/acylcarnitine carrier), member 29 0.580828
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha 0.573828
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 0.571495
DHRS2 dehydrogenase/reductase (SDR family) member 2 0.562558
FN1 fibronectin 1 0.555568
IMPACT impact RWD domain protein 0.549747
MUC2 mucin 2, oligomeric mucus/gel-forming 0.549359
TF transferrin 0.548195
BRI3 brain protein I3 0.540829
PTBP3 polypyrimidine tract binding protein 3 0.540055
MLX MLX, MAX dimerization protein 0.531928
TRIM39 tripartite motif containing 39 0.529222
EPX eosinophil peroxidase 0.525746
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic) 0.52536
CCL24 chemokine (C-C motif) ligand 24 0.52343
CCL2 chemokine (C-C motif) ligand 2 0.51611
SOD2 superoxide dismutase 2, mitochondrial 0.513417
CXCL9 chemokine (C-X-C motif) ligand 9 0.509959
CALCA calcitonin-related polypeptide alpha 0.499997
PELI1 pellino E3 ubiquitin protein ligase 1 0.491215
SNF8 SNF8, ESCRT-II complex subunit 0.490072
ACPP acid phosphatase, prostate 0.489311
EARS2 glutamyl-tRNA synthetase 2, mitochondrial 0.488169
ADRB2 adrenoceptor beta 2, surface 0.485125
DNASE1 deoxyribonuclease I 0.474877
TSPO translocator protein (18kDa) 0.47374
MME membrane metallo-endopeptidase 0.473361
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies) 0.471089
VCX variable charge, X-linked 0.466928
MMP9 matrix metallopeptidase 9 0.466928
TLR2 toll-like receptor 2 0.463149
CP ceruloplasmin (ferroxidase) 0.462016
GRP gastrin-releasing peptide 0.457487
SCNN1B sodium channel, non voltage gated 1 beta subunit 0.452585
AADACL3 arylacetamide deacetylase-like 3 0.450324
PLAT plasminogen activator, tissue 0.448441
F2 coagulation factor II (thrombin) 0.446935
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) 0.446182
VCX2 variable charge, X-linked 2 0.443171
MEFV Mediterranean fever 0.442042
CYP2S1 cytochrome P450, family 2, subfamily S, polypeptide 1 0.431144
CCR3 chemokine (C-C motif) receptor 3 0.42664
PI15 peptidase inhibitor 15 0.421016
CLCN6 chloride channel, voltage-sensitive 6 0.420266
MUC7 mucin 7, secreted 0.418019
KLK1 kallikrein 1 0.413153
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) 0.409414
HP haptoglobin 0.408292
VCX3B variable charge, X-linked 3B 0.407919
HPR haptoglobin-related protein 0.402318
IGHG2 immunoglobulin heavy constant gamma 2 (G2m marker) 0.401945
OXR1 oxidation resistance 1 0.399707
IL13 interleukin 13 0.394118
VCX3A variable charge, X-linked 3A 0.387423
IFNA5 interferon, alpha 5 0.385193
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.384822
HRH1 histamine receptor H1 0.382594
STYX serine/threonine/tyrosine interacting protein 0.379997
ZBTB32 zinc finger and BTB domain containing 32 0.378143
CHRFAM7A CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion 0.377031
LAP3 leucine aminopeptidase 3 0.377031
TFF3 trefoil factor 3 (intestinal) 0.376661
LCMT2 leucine carboxyl methyltransferase 2 0.37555
PPCS phosphopantothenoylcysteine synthetase 0.372958
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5 0.368518
CLNK cytokine-dependent hematopoietic cell linker 0.368149
GSTTP1 glutathione S-transferase theta pseudogene 1 0.36741
GSTT1 glutathione S-transferase theta 1 0.36741
ARMC10 armadillo repeat containing 10 0.365932
ETFA electron-transfer-flavoprotein, alpha polypeptide 0.364824
MLKL mixed lineage kinase domain-like 0.364085
CYP2F1 cytochrome P450, family 2, subfamily F, polypeptide 1 0.363347
FCGR1B Fc fragment of IgG, high affinity Ib, receptor (CD64) 0.353027
SCARF1 scavenger receptor class F, member 1 0.351187
FMN1 formin 1 0.347144
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 0.344574
PRAMEF10 PRAME family member 10 0.343473
MAD2L2 MAD2 mitotic arrest deficient-like 2 (yeast) 0.342372
ALPPL2 alkaline phosphatase, placental-like 2 0.333583
ALPP alkaline phosphatase, placental 0.333218
TACR2 tachykinin receptor 2 0.333218
ALPL alkaline phosphatase, liver/bone/kidney 0.332852
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker) 0.332487
CCL4 chemokine (C-C motif) ligand 4 0.331025
CHIC2 cysteine-rich hydrophobic domain 2 0.32993
VIPR1 vasoactive intestinal peptide receptor 1 0.328469
SFTPB surfactant protein B 0.327375
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.32701
PER1 period circadian clock 1 0.325552
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1 0.325187
NUP62 nucleoporin 62kDa 0.324823
MYD88 myeloid differentiation primary response 88 0.32373
TGFB1 transforming growth factor, beta 1 0.320817
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 0.320454
LAG3 lymphocyte-activation gene 3 0.313915
HBA2 hemoglobin, alpha 2 0.313915
STAT1 signal transducer and activator of transcription 1, 91kDa 0.313552
GGT1 gamma-glutamyltransferase 1 0.312464
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic) 0.308118
MPLKIP M-phase specific PLK1 interacting protein 0.30631
EGFR epidermal growth factor receptor 0.30342
COPB1 coatomer protein complex, subunit beta 1 0.301976
BLOC1S4 biogenesis of lysosomal organelles complex-1, subunit 4, cappuccino 0.300894
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 0.300533
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 0.300173
PRTN3 proteinase 3 0.299812
TARS threonyl-tRNA synthetase 0.297291
CLCA1 chloride channel accessory 1 0.294772
MMP1 matrix metallopeptidase 1 0.290103
TLE4 transducin-like enhancer of split 4 0.289386
DACT3 dishevelled-binding antagonist of beta-catenin 3 0.285444
MCM8 minichromosome maintenance complex component 8 0.281868
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin 0.279724
GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3 0.279724
CD1C CD1c molecule 0.275445
DCLK3 doublecortin-like kinase 3 0.272241
BCHE butyrylcholinesterase 0.271886
DNAH11 dynein, axonemal, heavy chain 11 0.271174
DUOXA2 dual oxidase maturation factor 2 0.270464
GET4 golgi to ER traffic protein 4 homolog (S. cerevisiae) 0.267977
MOCS2 molybdenum cofactor synthesis 2 0.267622
BBS9 Bardet-Biedl syndrome 9 0.266913
CLPP caseinolytic mitochondrial matrix peptidase proteolytic subunit 0.265849
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.265494
C11ORF40 chromosome 11 open reading frame 40 0.264785
CD19 CD19 molecule 0.263722
MARK1 MAP/microtubule affinity-regulating kinase 1 0.263014
OR4F29 olfactory receptor, family 4, subfamily F, member 29 0.261952
TTR transthyretin 0.260891
TIMP1 TIMP metallopeptidase inhibitor 1 0.260184
ADAM2 ADAM metallopeptidase domain 2 0.25983
SHKBP1 SH3KBP1 binding protein 1 0.252422
ST3GAL3 ST3 beta-galactoside alpha-2,3-sialyltransferase 3 0.245046
GC group-specific component (vitamin D binding protein) 0.244696
PPIG peptidylprolyl isomerase G (cyclophilin G) 0.241196
VIPR2 vasoactive intestinal peptide receptor 2 0.238752
RNF19B ring finger protein 19B 0.237357
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1 0.237357
OR10K1 olfactory receptor, family 10, subfamily K, member 1 0.236312
BANF1 barrier to autointegration factor 1 0.233183
ICAM3 intercellular adhesion molecule 3 0.230063
STPG1 sperm-tail PG-rich repeat containing 1 0.229716
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 0.22937
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 0.228333
KLKB1 kallikrein B, plasma (Fletcher factor) 1 0.227988
POU2F1 POU class 2 homeobox 1 0.227297
BHLHE22 basic helix-loop-helix family, member e22 0.226262
CXCR2 chemokine (C-X-C motif) receptor 2 0.223165
CTSB cathepsin B 0.222479
C3 complement component 3 0.217693
SPATA21 spermatogenesis associated 21 0.217693
GSTP1 glutathione S-transferase pi 1 0.217352
ESD esterase D 0.216672
GAN gigaxonin 0.216332
HSPA4 heat shock 70kDa protein 4 0.215653
IL5RA interleukin 5 receptor, alpha 0.214636
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 0.212608
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 0.210589
SCGB3A2 secretoglobin, family 3A, member 2 0.210253
CD248 CD248 molecule, endosialin 0.209248
IGLV2-14 immunoglobulin lambda variable 2-14 0.206913
CLEC4M C-type lectin domain family 4, member M 0.204593
AHR aryl hydrocarbon receptor 0.204593
FXYD5 FXYD domain containing ion transport regulator 5 0.203275
IRF1 interferon regulatory factor 1 0.203275
RER1 retention in endoplasmic reticulum sorting receptor 1 0.202946
IL17F interleukin 17F 0.201962
ANO1 anoctamin 1, calcium activated chloride channel 0.201962
TRPC7 transient receptor potential cation channel, subfamily C, member 7 0.199681
PLAGL2 pleiomorphic adenoma gene-like 2 0.197742
NOS2 nitric oxide synthase 2, inducible 0.196139
FTL ferritin, light polypeptide 0.194865
FTH1 ferritin, heavy polypeptide 1 0.194865
NCBP1 nuclear cap binding protein subunit 1, 80kDa 0.1936
PLEKHN1 pleckstrin homology domain containing, family N member 1 0.192971
SCNN1D sodium channel, non voltage gated 1 delta subunit 0.192657
CPM carboxypeptidase M 0.188938
ACE2 angiotensin I converting enzyme 2 0.188632
IFNL2 interferon, lambda 2 0.188632
PNOC prepronociceptin 0.186811
SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 0.18651
EPRS glutamyl-prolyl-tRNA synthetase 0.184128
FOXJ1 forkhead box J1 0.183248
TFF1 trefoil factor 1 0.182375
PRSS21 protease, serine, 21 (testisin) 0.182375
TLR3 toll-like receptor 3 0.181798
BIN3 bridging integrator 3 0.181222
PGM1 phosphoglucomutase 1 0.178126
IFITM3 interferon induced transmembrane protein 3 0.178126
PAPD7 PAP associated domain containing 7 0.176757
CXCL2 chemokine (C-X-C motif) ligand 2 0.175146
BMP8B bone morphogenetic protein 8b 0.173571
MBL2 mannose-binding lectin (protein C) 2, soluble 0.172799
PLA2G2D phospholipase A2, group IID 0.172291
EVC2 Ellis van Creveld syndrome 2 0.170544
LACTB lactamase, beta 0.166995
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6 0.166319
CCDC27 coiled-coil domain containing 27 0.166095
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 0.165001
CSN1S1 casein alpha s1 0.163729
AVP arginine vasopressin 0.163523
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.163111
CYLD cylindromatosis (turban tumor syndrome) 0.162707
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 0.161139
GUSB glucuronidase, beta 0.160574
CMA1 chymase 1, mast cell 0.159658
SELE selectin E 0.157929