brucellosis Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
Description A primary bacterial infectious disease that is caused by the bacteria of the genus Brucella, when humans come in contact with contaminated animals or animal products or ingestion of infected food products. The disease has_symptom fever, has_symptom sweat, has_symptom headache, has_symptom back pain, has_symptom physical weakness, has_symptom joint pain and has_symptom fatigue. (Human Disease Ontology, DOID_11077)
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Genes

129 genes co-occuring with the disease brucellosis in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
REV1 REV1, polymerase (DNA directed) 2.77023
MEFV Mediterranean fever 2.44083
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 1.89638
STAB2 stabilin 2 1.40307
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 1.3712
CD79A CD79a molecule, immunoglobulin-associated alpha 1.25515
RPL9 ribosomal protein L9 1.24732
LRP5 low density lipoprotein receptor-related protein 5 1.23733
PSG8 pregnancy specific beta-1-glycoprotein 8 1.20613
SPSB3 splA/ryanodine receptor domain and SOCS box containing 3 1.08202
CRP C-reactive protein, pentraxin-related 1.07488
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) 1.04714
SPSB4 splA/ryanodine receptor domain and SOCS box containing 4 1.04209
KDM5D lysine (K)-specific demethylase 5D 1.01891
PI3 peptidase inhibitor 3, skin-derived 0.996549
MYD88 myeloid differentiation primary response 88 0.954943
CD4 CD4 molecule 0.950352
FBXO21 F-box protein 21 0.928759
LYZ lysozyme 0.906909
NABP1 nucleic acid binding protein 1 0.88434
TLR2 toll-like receptor 2 0.842982
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.842163
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) 0.818385
GPR162 G protein-coupled receptor 162 0.812232
KCNH3 potassium channel, voltage gated eag related subfamily H, member 3 0.770027
HTRA1 HtrA serine peptidase 1 0.756156
IL4 interleukin 4 0.753713
TLR4 toll-like receptor 4 0.750457
LAMP1 lysosomal-associated membrane protein 1 0.721673
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B 0.717232
MAN2A1 mannosidase, alpha, class 2A, member 1 0.715215
IRF1 interferon regulatory factor 1 0.709169
PLEK2 pleckstrin 2 0.701526
GPR84 G protein-coupled receptor 84 0.699517
TNF tumor necrosis factor 0.6939
RPS12 ribosomal protein S12 0.688692
MVK mevalonate kinase 0.688291
NLRC4 NLR family, CARD domain containing 4 0.678701
SGSM3 small G protein signaling modulator 3 0.668345
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 0.665166
CREG1 cellular repressor of E1A-stimulated genes 1 0.646559
IFI30 interferon, gamma-inducible protein 30 0.646165
WDR13 WD repeat domain 13 0.644981
ARRDC3 arrestin domain containing 3 0.638282
NUBPL nucleotide binding protein-like 0.632777
ERLIN2 ER lipid raft associated 2 0.622967
SAA2 serum amyloid A2 0.621008
MID1 midline 1 0.619834
NLRP3 NLR family, pyrin domain containing 3 0.610057
NFU1 NFU1 iron-sulfur cluster scaffold 0.60303
EMC3 ER membrane protein complex subunit 3 0.581606
PPP1R14A protein phosphatase 1, regulatory (inhibitor) subunit 14A 0.579661
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F 0.561392
METAP1 methionyl aminopeptidase 1 0.521888
ARSI arylsulfatase family, member I 0.513417
SAA1 serum amyloid A1 0.498085
IFNG interferon, gamma 0.493122
CLPP caseinolytic mitochondrial matrix peptidase proteolytic subunit 0.490072
SLC30A2 solute carrier family 30 (zinc transporter), member 2 0.474119
BDKRB2 bradykinin receptor B2 0.469954
RAB2A RAB2A, member RAS oncogene family 0.466928
TSPO translocator protein (18kDa) 0.46466
CASC5 cancer susceptibility candidate 5 0.453716
PRRC2A proline-rich coiled-coil 2A 0.449947
IL2 interleukin 2 0.438282
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 0.434899
MAP6 microtubule-associated protein 6 0.430393
VDAC2 voltage-dependent anion channel 2 0.430393
ADA adenosine deaminase 0.429266
RFXANK regulatory factor X-associated ankyrin-containing protein 0.428516
TCHH trichohyalin 0.417644
ATP5B ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide 0.410909
CD69 CD69 molecule 0.410535
NONO non-POU domain containing, octamer-binding 0.389281
BIRC6 baculoviral IAP repeat containing 6 0.382594
TLR9 toll-like receptor 9 0.380368
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1) 0.373328
CYTIP cytohesin 1 interacting protein 0.368518
CASP2 caspase 2, apoptosis-related cysteine peptidase 0.365193
ULBP1 UL16 binding protein 1 0.361133
CHAD chondroadherin 0.35082
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 0.340539
BID BH3 interacting domain death agonist 0.337608
MDH2 malate dehydrogenase 2, NAD (mitochondrial) 0.323365
ADORA2B adenosine A2b receptor 0.315003
ANPEP alanyl (membrane) aminopeptidase 0.308118
TES testin LIM domain protein 0.307757
TLR10 toll-like receptor 10 0.30631
CD80 CD80 molecule 0.302337
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1 0.285802
IL1RN interleukin 1 receptor antagonist 0.284728
HCAR2 hydroxycarboxylic acid receptor 2 0.279724
IL18 interleukin 18 0.276514
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1 0.270819
CAND2 cullin-associated and neddylation-dissociated 2 (putative) 0.264077
METAP2 methionyl aminopeptidase 2 0.26266
POMC proopiomelanocortin 0.26266
IL10 interleukin 10 0.261245
CXCL8 chemokine (C-X-C motif) ligand 8 0.260184
ASL argininosuccinate lyase 0.259477
TMPO thymopoietin 0.256652
TUB tubby bipartite transcription factor 0.246448
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein 0.245396
MICA MHC class I polypeptide-related sequence A 0.240148
EGR3 early growth response 3 0.23945
ALPPL2 alkaline phosphatase, placental-like 2 0.238403
ALPP alkaline phosphatase, placental 0.238054
ALPL alkaline phosphatase, liver/bone/kidney 0.237357
IL1B interleukin 1, beta 0.23353
MRAP melanocortin 2 receptor accessory protein 0.230755
TMEM173 transmembrane protein 173 0.22454
LY75 lymphocyte antigen 75 0.222479
CSF1 colony stimulating factor 1 (macrophage) 0.220081
CARD17 caspase recruitment domain family, member 17 0.220081
CD9 CD9 molecule 0.217012
EEA1 early endosome antigen 1 0.212608
WDR11 WD repeat domain 11 0.210589
AIM2 absent in melanoma 2 0.207245
ACOT13 acyl-CoA thioesterase 13 0.205585
IL18BP interleukin 18 binding protein 0.200656
IRAK4 interleukin-1 receptor-associated kinase 4 0.19582
GRHL1 grainyhead-like 1 (Drosophila) 0.194548
HLA-B major histocompatibility complex, class I, B 0.192344
SCNN1A sodium channel, non voltage gated 1 alpha subunit 0.177029
DYNLT1 dynein, light chain, Tctex-type 1 0.165435
NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit 0.164571
DSPP dentin sialophosphoprotein 0.160574
BIRC7 baculoviral IAP repeat containing 7 0.159658
IL12B interleukin 12B 0.158951