bucladesine-591 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the bucladesine-591 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACAN aggrecan
ACVR1B activin A receptor, type IB
AHSP alpha hemoglobin stabilizing protein
AKTIP AKT interacting protein
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
AMBRA1 autophagy/beclin-1 regulator 1
ATP5S ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B)
BAZ2B bromodomain adjacent to zinc finger domain, 2B
BCR breakpoint cluster region
BICD2 bicaudal D homolog 2 (Drosophila)
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CBFB core-binding factor, beta subunit
CCL19 chemokine (C-C motif) ligand 19
CCPG1 cell cycle progression 1
CDYL chromodomain protein, Y-like
CENPT centromere protein T
CEP68 centrosomal protein 68kDa
CNOT2 CCR4-NOT transcription complex, subunit 2
CNTD2 cyclin N-terminal domain containing 2
DCP1A decapping mRNA 1A
DERL1 derlin 1
DIO2 deiodinase, iodothyronine, type II
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3
EPS8L1 EPS8-like 1
ETNK1 ethanolamine kinase 1
EXOC7 exocyst complex component 7
EXOSC9 exosome component 9
F2RL1 coagulation factor II (thrombin) receptor-like 1
FASTK Fas-activated serine/threonine kinase
FEM1B fem-1 homolog b (C. elegans)
FGFR1 fibroblast growth factor receptor 1
FOXC1 forkhead box C1
FXR2 fragile X mental retardation, autosomal homolog 2
GAST gastrin
GPR21 G protein-coupled receptor 21
GRIP2 glutamate receptor interacting protein 2
HACD2 3-hydroxyacyl-CoA dehydratase 2
HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor
HLA-E major histocompatibility complex, class I, E
ICA1 islet cell autoantigen 1, 69kDa
IQSEC1 IQ motif and Sec7 domain 1
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KIAA0141 KIAA0141
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial)
LMNB1 lamin B1
LPIN2 lipin 2
MAPT microtubule-associated protein tau
MBP myelin basic protein
MT1HL1 metallothionein 1H-like 1
NCAPH2 non-SMC condensin II complex, subunit H2
NCOA1 nuclear receptor coactivator 1
NFIC nuclear factor I/C (CCAAT-binding transcription factor)
NGLY1 N-glycanase 1
NPPA natriuretic peptide A
NR4A1 nuclear receptor subfamily 4, group A, member 1
ORC4 origin recognition complex, subunit 4
P3H4 prolyl 3-hydroxylase family member 4 (non-enzymatic)
PARG poly (ADP-ribose) glycohydrolase
PCDHB3 protocadherin beta 3
PEX11A peroxisomal biogenesis factor 11 alpha
PHKA2 phosphorylase kinase, alpha 2 (liver)
PIGV phosphatidylinositol glycan anchor biosynthesis, class V
PRB1 proline-rich protein BstNI subfamily 1
PRDM11 PR domain containing 11
PRDX2 peroxiredoxin 2
PRRC2A proline-rich coiled-coil 2A
RAD54L RAD54-like (S. cerevisiae)
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RRP1B ribosomal RNA processing 1B
SH3BP2 SH3-domain binding protein 2
SHMT1 serine hydroxymethyltransferase 1 (soluble)
SIGMAR1 sigma non-opioid intracellular receptor 1
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SNAPC4 small nuclear RNA activating complex, polypeptide 4, 190kDa
SOAT1 sterol O-acyltransferase 1
SPA17 sperm autoantigenic protein 17
SSH3 slingshot protein phosphatase 3
SZRD1 SUZ RNA binding domain containing 1
TBRG4 transforming growth factor beta regulator 4
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
TNK1 tyrosine kinase, non-receptor, 1
TPST2 tyrosylprotein sulfotransferase 2
TRADD TNFRSF1A-associated via death domain
TRAPPC12 trafficking protein particle complex 12
TRIM29 tripartite motif containing 29
TTC39A tetratricopeptide repeat domain 39A
UBL3 ubiquitin-like 3
UQCC1 ubiquinol-cytochrome c reductase complex assembly factor 1
WNT7A wingless-type MMTV integration site family, member 7A
WSCD1 WSC domain containing 1
YKT6 YKT6 v-SNARE homolog (S. cerevisiae)
ZBTB43 zinc finger and BTB domain containing 43
ZNF140 zinc finger protein 140
ZNF473 zinc finger protein 473
ZNF609 zinc finger protein 609
ZNHIT2 zinc finger, HIT-type containing 2

decreased expression

Symbol Name
A4GNT alpha-1,4-N-acetylglucosaminyltransferase
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ACIN1 apoptotic chromatin condensation inducer 1
ACSF2 acyl-CoA synthetase family member 2
ADAMTSL4 ADAMTS-like 4
ADAP2 ArfGAP with dual PH domains 2
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ATG10 autophagy related 10
AXIN1 axin 1
BCL2L14 BCL2-like 14 (apoptosis facilitator)
BCORL1 BCL6 corepressor-like 1
BTNL3 butyrophilin-like 3
C16ORF59 chromosome 16 open reading frame 59
C5ORF45 chromosome 5 open reading frame 45
CA9 carbonic anhydrase IX
CARTPT CART prepropeptide
CCZ1 CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae)
CD2 CD2 molecule
CD82 CD82 molecule
CDC42BPB CDC42 binding protein kinase beta (DMPK-like)
CIDEB cell death-inducing DFFA-like effector b
CLEC4E C-type lectin domain family 4, member E
CP ceruloplasmin (ferroxidase)
CPNE7 copine VII
CROT carnitine O-octanoyltransferase
CSN2 casein beta
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6
DNMBP dynamin binding protein
DOK5 docking protein 5
DSCAM Down syndrome cell adhesion molecule
DUSP5 dual specificity phosphatase 5
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3
EPHA2 EPH receptor A2
EPS8L3 EPS8-like 3
ETNK2 ethanolamine kinase 2
FAM189A2 family with sequence similarity 189, member A2
FGFBP1 fibroblast growth factor binding protein 1
FUZ fuzzy planar cell polarity protein
GP6 glycoprotein VI (platelet)
GPATCH2L G patch domain containing 2-like
GPRC5D G protein-coupled receptor, class C, group 5, member D
GPX2 glutathione peroxidase 2
GRPR gastrin-releasing peptide receptor
GTF2H2B general transcription factor IIH, polypeptide 2B (pseudogene)
H2AFY2 H2A histone family, member Y2
HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
HOXC5 homeobox C5
IRF9 interferon regulatory factor 9
KRT1 keratin 1, type II
KRT38 keratin 38, type I
KRT9 keratin 9, type I
LAMB3 laminin, beta 3
LCN1 lipocalin 1
LIN7B lin-7 homolog B (C. elegans)
LLGL2 lethal giant larvae homolog 2 (Drosophila)
LMBR1L limb development membrane protein 1-like
LOC642236 FSHD region gene 1 pseudogene
LONRF3 LON peptidase N-terminal domain and ring finger 3
LRRC15 leucine rich repeat containing 15
LUZP4 leucine zipper protein 4
MLN motilin
MYO1E myosin IE
NPIPB15 nuclear pore complex interacting protein family, member B15
NR1D2 nuclear receptor subfamily 1, group D, member 2
NUAK1 NUAK family, SNF1-like kinase, 1
OR10H3 olfactory receptor, family 10, subfamily H, member 3
OR10J1 olfactory receptor, family 10, subfamily J, member 1
OR1D2 olfactory receptor, family 1, subfamily D, member 2
OXTR oxytocin receptor
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PGS1 phosphatidylglycerophosphate synthase 1
PTPRT protein tyrosine phosphatase, receptor type, T
RAB4B RAB4B, member RAS oncogene family
RASL11B RAS-like, family 11, member B
RLBP1 retinaldehyde binding protein 1
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SCN10A sodium channel, voltage gated, type X alpha subunit
SCPEP1 serine carboxypeptidase 1
SELL selectin L
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
SUSD4 sushi domain containing 4
TEX40 testis expressed 40
THBS4 thrombospondin 4
TMEM206 transmembrane protein 206
TMPRSS5 transmembrane protease, serine 5
TNS2 tensin 2
TPST1 tyrosylprotein sulfotransferase 1
TTC4 tetratricopeptide repeat domain 4
UBTD1 ubiquitin domain containing 1
XYLT2 xylosyltransferase II
ZFHX4 zinc finger homeobox 4
ZNF219 zinc finger protein 219
ZNF507 zinc finger protein 507
ZNF510 zinc finger protein 510