bucladesine-842 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the bucladesine-842 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADGRB2 adhesion G protein-coupled receptor B2
AFAP1 actin filament associated protein 1
AMACR alpha-methylacyl-CoA racemase
ANXA2P3 annexin A2 pseudogene 3
APOE apolipoprotein E
ARHGAP35 Rho GTPase activating protein 35
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma
BTBD7 BTB (POZ) domain containing 7
C5AR2 complement component 5a receptor 2
CA5BP1 carbonic anhydrase VB pseudogene 1
CADM3 cell adhesion molecule 3
CCDC93 coiled-coil domain containing 93
CCP110 centriolar coiled coil protein 110kDa
CD52 CD52 molecule
CEP68 centrosomal protein 68kDa
CLCN5 chloride channel, voltage-sensitive 5
CORT cortistatin
CUL2 cullin 2
CYLC1 cylicin, basic protein of sperm head cytoskeleton 1
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
DCX doublecortin
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29
DIEXF digestive organ expansion factor homolog (zebrafish)
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
ENOX2 ecto-NOX disulfide-thiol exchanger 2
FCMR Fc fragment of IgM receptor
FER1L4 fer-1-like family member 4, pseudogene (functional)
FOXC1 forkhead box C1
FRMD8 FERM domain containing 8
GBP2 guanylate binding protein 2, interferon-inducible
HIST1H3B histone cluster 1, H3b
HIST2H2AA3 histone cluster 2, H2aa3
HRASLS2 HRAS-like suppressor 2
IFT54 intraflagellar transport 54
IPO8 importin 8
ITGB5 integrin, beta 5
KCNG1 potassium channel, voltage gated modifier subfamily G, member 1
KIAA0894 KIAA0894 protein
LIG3 ligase III, DNA, ATP-dependent
LIG4 ligase IV, DNA, ATP-dependent
LNPEP leucyl/cystinyl aminopeptidase
LRRC1 leucine rich repeat containing 1
LYRM9 LYR motif containing 9
MAPK14 mitogen-activated protein kinase 14
MCOLN3 mucolipin 3
MZT2B mitotic spindle organizing protein 2B
NDRG2 NDRG family member 2
NEB nebulin
NKX3-2 NK3 homeobox 2
NPIPB15 nuclear pore complex interacting protein family, member B15
NRF1 nuclear respiratory factor 1
OXTR oxytocin receptor
PCM1 pericentriolar material 1
PDE11A phosphodiesterase 11A
PDLIM7 PDZ and LIM domain 7 (enigma)
PDS5B PDS5 cohesin associated factor B
PIN4 peptidylprolyl cis/trans isomerase, NIMA-interacting 4
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLXNA1 plexin A1
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
PPFIA3 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
PROS1 protein S (alpha)
PVT1 Pvt1 oncogene (non-protein coding)
RAB3D RAB3D, member RAS oncogene family
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RANBP1 RAN binding protein 1
RASA2 RAS p21 protein activator 2
RBM12B-AS1 RBM12B antisense RNA 1
RREB1 ras responsive element binding protein 1
SGSM3 small G protein signaling modulator 3
SH2D4A SH2 domain containing 4A
SIPA1 signal-induced proliferation-associated 1
SIRAL2 SIR2 antiphage like 2
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC38A7 solute carrier family 38, member 7
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SNAPC5 small nuclear RNA activating complex, polypeptide 5, 19kDa
SOGA1 suppressor of glucose, autophagy associated 1
SPRR2B small proline-rich protein 2B
SSPN sarcospan
SZT2 seizure threshold 2 homolog (mouse)
TEX261 testis expressed 261
TFG TRK-fused gene
TLK1 tousled-like kinase 1
TPMT thiopurine S-methyltransferase
TRIM66 tripartite motif containing 66
TTC30A tetratricopeptide repeat domain 30A
WDFY3 WD repeat and FYVE domain containing 3
WDR91 WD repeat domain 91
WNK1 WNK lysine deficient protein kinase 1
ZBTB33 zinc finger and BTB domain containing 33
ZKSCAN5 zinc finger with KRAB and SCAN domains 5
ZNF219 zinc finger protein 219

decreased expression

Symbol Name
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
AGO3 argonaute RISC catalytic component 3
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
ANKHD1 ankyrin repeat and KH domain containing 1
BAHCC1 BAH domain and coiled-coil containing 1
BEX4 brain expressed, X-linked 4
C5 complement component 5
C6ORF47 chromosome 6 open reading frame 47
CAMKMT calmodulin-lysine N-methyltransferase
CARD8 caspase recruitment domain family, member 8
CBX8 chromobox homolog 8
CCDC85C coiled-coil domain containing 85C
CCNO cyclin O
CEP162 centrosomal protein 162kDa
CHEK2 checkpoint kinase 2
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CLSPN claspin
CRLF1 cytokine receptor-like factor 1
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae)
DSE dermatan sulfate epimerase
DUSP8 dual specificity phosphatase 8
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
EPPK1 epiplakin 1
FA2H fatty acid 2-hydroxylase
FBRS fibrosin
FSD1 fibronectin type III and SPRY domain containing 1
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GPATCH2L G patch domain containing 2-like
GPRASP1 G protein-coupled receptor associated sorting protein 1
GTPBP2 GTP binding protein 2
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
GUF1 GUF1 GTPase homolog (S. cerevisiae)
HOOK1 hook microtubule-tethering protein 1
IFT81 intraflagellar transport 81
IGFBP6 insulin-like growth factor binding protein 6
IP6K1 inositol hexakisphosphate kinase 1
IRF2 interferon regulatory factor 2
IRF2BP1 interferon regulatory factor 2 binding protein 1
IRF7 interferon regulatory factor 7
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KIAA0556 KIAA0556
LHX6 LIM homeobox 6
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LRRC49 leucine rich repeat containing 49
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAP9 microtubule-associated protein 9
MATK megakaryocyte-associated tyrosine kinase
MTSS1L metastasis suppressor 1-like
NAG18 NAG18 mRNA
NECAB3 N-terminal EF-hand calcium binding protein 3
NKAIN1 Na+/K+ transporting ATPase interacting 1
NUPL2 nucleoporin like 2
PIGN phosphatidylinositol glycan anchor biosynthesis, class N
PMP22 peripheral myelin protein 22
POLR1B polymerase (RNA) I polypeptide B, 128kDa
POTEKP POTE ankyrin domain family, member K, pseudogene
PRR7 proline rich 7 (synaptic)
PTK6 protein tyrosine kinase 6
PTTG3P pituitary tumor-transforming 3, pseudogene
REPS2 RALBP1 associated Eps domain containing 2
RHBG Rh family, B glycoprotein (gene/pseudogene)
RIBC2 RIB43A domain with coiled-coils 2
RNF2 ring finger protein 2
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
SCN1B sodium channel, voltage gated, type I beta subunit
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SH2B3 SH2B adaptor protein 3
SLC26A6 solute carrier family 26 (anion exchanger), member 6
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SNHG3 small nucleolar RNA host gene 3
SNX16 sorting nexin 16
SPINK4 serine peptidase inhibitor, Kazal type 4
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TBC1D17 TBC1 domain family, member 17
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TICAM1 toll-like receptor adaptor molecule 1
TIGD6 tigger transposable element derived 6
TMUB2 transmembrane and ubiquitin-like domain containing 2
TPST2 tyrosylprotein sulfotransferase 2
TRAPPC11 trafficking protein particle complex 11
TSPAN14 tetraspanin 14
USP36 ubiquitin specific peptidase 36
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
VEGFC vascular endothelial growth factor C
VKORC1 vitamin K epoxide reductase complex, subunit 1
VPS11 vacuolar protein sorting 11 homolog (S. cerevisiae)
WBP2 WW domain binding protein 2
ZC3H3 zinc finger CCCH-type containing 3
ZCCHC8 zinc finger, CCHC domain containing 8
ZFHX3 zinc finger homeobox 3
ZMYM1 zinc finger, MYM-type 1
ZNF134 zinc finger protein 134
ZNF532 zinc finger protein 532
ZNF551 zinc finger protein 551
ZNF669 zinc finger protein 669
ZNF787 zinc finger protein 787
ZNF813 zinc finger protein 813
ZNF862 zinc finger protein 862
ZW10 zw10 kinetochore protein