bucladesine-959 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the bucladesine-959 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
ALPK1 alpha-kinase 1
ANP32A-IT1 ANP32A intronic transcript 1
ATG3 autophagy related 3
ATP9A ATPase, class II, type 9A
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
BCL7A B-cell CLL/lymphoma 7A
BSPRY B-box and SPRY domain containing
C7ORF43 chromosome 7 open reading frame 43
CAMSAP1 calmodulin regulated spectrin-associated protein 1
CARS2 cysteinyl-tRNA synthetase 2, mitochondrial (putative)
CBX7 chromobox homolog 7
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CEP152 centrosomal protein 152kDa
CEP164 centrosomal protein 164kDa
CFLAR CASP8 and FADD-like apoptosis regulator
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CLIP4 CAP-GLY domain containing linker protein family, member 4
CLN8 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
DIEXF digestive organ expansion factor homolog (zebrafish)
DTX2P1-UPK3BP1-PMS2P11 DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene
E2F4 E2F transcription factor 4, p107/p130-binding
ELOVL2 ELOVL fatty acid elongase 2
EPHB4 EPH receptor B4
FAM188A family with sequence similarity 188, member A
FANCA Fanconi anemia, complementation group A
FCF1 FCF1 rRNA-processing protein
FGFR2 fibroblast growth factor receptor 2
FLOT2 flotillin 2
FOXN3 forkhead box N3
GEM GTP binding protein overexpressed in skeletal muscle
GPR153 G protein-coupled receptor 153
HAUS2 HAUS augmin-like complex, subunit 2
HLA-E major histocompatibility complex, class I, E
HLA-J major histocompatibility complex, class I, J (pseudogene)
HMGXB3 HMG box domain containing 3
HMOX2 heme oxygenase 2
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
IL4R interleukin 4 receptor
INTS7 integrator complex subunit 7
ITFG2 integrin alpha FG-GAP repeat containing 2
KLHL24 kelch-like family member 24
LDB1 LIM domain binding 1
LMNA lamin A/C
MAN2C1 mannosidase, alpha, class 2C, member 1
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MTRF1L mitochondrial translational release factor 1-like
MZT2B mitotic spindle organizing protein 2B
N4BP1 NEDD4 binding protein 1
NAIP NLR family, apoptosis inhibitory protein
NR2F6 nuclear receptor subfamily 2, group F, member 6
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NR6A1 nuclear receptor subfamily 6, group A, member 1
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
OGFR opioid growth factor receptor
PDCD2 programmed cell death 2
PHOX2B paired-like homeobox 2b
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PIN4 peptidylprolyl cis/trans isomerase, NIMA-interacting 4
PLA2G10 phospholipase A2, group X
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PSD3 pleckstrin and Sec7 domain containing 3
PTPRU protein tyrosine phosphatase, receptor type, U
R3HDM1 R3H domain containing 1
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RPS3A ribosomal protein S3A
RUFY3 RUN and FYVE domain containing 3
SEC24D SEC24 family member D
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SGSM2 small G protein signaling modulator 2
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SOD2 superoxide dismutase 2, mitochondrial
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
SREK1IP1 SREK1-interacting protein 1
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4
STARD5 StAR-related lipid transfer (START) domain containing 5
TAOK1 TAO kinase 1
TLN2 talin 2
TRAPPC9 trafficking protein particle complex 9
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TUBA3C tubulin, alpha 3c
TXNL4A thioredoxin-like 4A
UBQLN4 ubiquilin 4
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
USB1 U6 snRNA biogenesis 1
USP36 ubiquitin specific peptidase 36
VASH2 vasohibin 2
VWA5A von Willebrand factor A domain containing 5A
XK X-linked Kx blood group
ZDHHC14 zinc finger, DHHC-type containing 14
ZNF134 zinc finger protein 134
ZNF250 zinc finger protein 250
ZNF34 zinc finger protein 34
ZNF768 zinc finger protein 768
ZSCAN26 zinc finger and SCAN domain containing 26

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ABHD4 abhydrolase domain containing 4
ABLIM3 actin binding LIM protein family, member 3
ATP7B ATPase, Cu++ transporting, beta polypeptide
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BCL9 B-cell CLL/lymphoma 9
C1ORF56 chromosome 1 open reading frame 56
C5 complement component 5
C5ORF45 chromosome 5 open reading frame 45
CARD8 caspase recruitment domain family, member 8
CBLL1 Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase
CCDC91 coiled-coil domain containing 91
CCP110 centriolar coiled coil protein 110kDa
CD151 CD151 molecule (Raph blood group)
CENPJ centromere protein J
CEP97 centrosomal protein 97kDa
CHIC2 cysteine-rich hydrophobic domain 2
CISH cytokine inducible SH2-containing protein
CLSPN claspin
CNPY3 canopy FGF signaling regulator 3
COX16 COX16 cytochrome c oxidase assembly homolog (S. cerevisiae)
CPTP ceramide-1-phosphate transfer protein
CUEDC1 CUE domain containing 1
CXORF56 chromosome X open reading frame 56
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DCAF17 DDB1 and CUL4 associated factor 17
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila)
DNAL4 dynein, axonemal, light chain 4
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
EMD emerin
FAAH fatty acid amide hydrolase
FAM155B family with sequence similarity 155, member B
FANCC Fanconi anemia, complementation group C
FBXO5 F-box protein 5
FEM1C fem-1 homolog c (C. elegans)
FILIP1L filamin A interacting protein 1-like
FKBP5 FK506 binding protein 5
FMO4 flavin containing monooxygenase 4
FRS2 fibroblast growth factor receptor substrate 2
FUZ fuzzy planar cell polarity protein
GCHFR GTP cyclohydrolase I feedback regulator
GLB1L2 galactosidase, beta 1-like 2
GLCE glucuronic acid epimerase
GPR87 G protein-coupled receptor 87
GSTM2 glutathione S-transferase mu 2 (muscle)
HAUS6 HAUS augmin-like complex, subunit 6
HIRA histone cell cycle regulator
IFIT5 interferon-induced protein with tetratricopeptide repeats 5
IRX4 iroquois homeobox 4
JRKL JRK-like
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LMNB1 lamin B1
MB myoglobin
MDM4 MDM4, p53 regulator
METTL2B methyltransferase like 2B
MKLN1 muskelin 1, intracellular mediator containing kelch motifs
MRPL2 mitochondrial ribosomal protein L2
MT1H metallothionein 1H
MTA2 metastasis associated 1 family, member 2
MTHFSD methenyltetrahydrofolate synthetase domain containing
MVD mevalonate (diphospho) decarboxylase
NECAB3 N-terminal EF-hand calcium binding protein 3
NR2C2 nuclear receptor subfamily 2, group C, member 2
OSMR oncostatin M receptor
OXTR oxytocin receptor
PARD6A par-6 family cell polarity regulator alpha
PARP12 poly (ADP-ribose) polymerase family, member 12
PEX26 peroxisomal biogenesis factor 26
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PNPLA6 patatin-like phospholipase domain containing 6
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
PRSS8 protease, serine, 8
PSKH1 protein serine kinase H1
RFX7 regulatory factor X, 7
RPL23AP7 ribosomal protein L23a pseudogene 7
RRP9 ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)
SAMHD1 SAM domain and HD domain 1
SARS2 seryl-tRNA synthetase 2, mitochondrial
SIDT1 SID1 transmembrane family, member 1
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter)
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SOX12 SRY (sex determining region Y)-box 12
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
TESK1 testis-specific kinase 1
THNSL1 threonine synthase-like 1 (S. cerevisiae)
TNRC6B trinucleotide repeat containing 6B
TRAPPC11 trafficking protein particle complex 11
TRNAU1AP tRNA selenocysteine 1 associated protein 1
TTC4 tetratricopeptide repeat domain 4
ZNF574 zinc finger protein 574
ZNF639 zinc finger protein 639
ZNF675 zinc finger protein 675