budesonide-1716 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the budesonide-1716 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACACB acetyl-CoA carboxylase beta
ACRV1 acrosomal vesicle protein 1
ACSL1 acyl-CoA synthetase long-chain family member 1
ADORA3 adenosine A3 receptor
AKAP13 A kinase (PRKA) anchor protein 13
AMBRA1 autophagy/beclin-1 regulator 1
APOM apolipoprotein M
AREG amphiregulin
BCAT1 branched chain amino-acid transaminase 1, cytosolic
BIN1 bridging integrator 1
C2CD2L C2CD2-like
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CCDC40 coiled-coil domain containing 40
CCNA1 cyclin A1
CEP68 centrosomal protein 68kDa
CETN1 centrin, EF-hand protein, 1
CLTCL1 clathrin, heavy chain-like 1
CPD carboxypeptidase D
CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
DDIT4 DNA-damage-inducible transcript 4
DNAL4 dynein, axonemal, light chain 4
DUSP1 dual specificity phosphatase 1
ELK1 ELK1, member of ETS oncogene family
EPAS1 endothelial PAS domain protein 1
EVA1B eva-1 homolog B (C. elegans)
F3 coagulation factor III (thromboplastin, tissue factor)
FES FES proto-oncogene, tyrosine kinase
FKBP5 FK506 binding protein 5
FLT3 fms-related tyrosine kinase 3
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GNS glucosamine (N-acetyl)-6-sulfatase
GSN gelsolin
HUS1 HUS1 checkpoint homolog (S. pombe)
IFNGR1 interferon gamma receptor 1
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL13RA1 interleukin 13 receptor, alpha 1
IL1R1 interleukin 1 receptor, type I
IL1R2 interleukin 1 receptor, type II
INSR insulin receptor
IRAK3 interleukin-1 receptor-associated kinase 3
IRS2 insulin receptor substrate 2
ISG20 interferon stimulated exonuclease gene 20kDa
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KLF13 Kruppel-like factor 13
KLF9 Kruppel-like factor 9
KRT18 keratin 18, type I
LDLRAP1 low density lipoprotein receptor adaptor protein 1
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LMAN1 lectin, mannose-binding, 1
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LPL lipoprotein lipase
METTL7A methyltransferase like 7A
MFN1 mitofusin 1
MLH3 mutL homolog 3
MT1F metallothionein 1F
MT1X metallothionein 1X
MT2A metallothionein 2A
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NFYA nuclear transcription factor Y, alpha
NLRP3 NLR family, pyrin domain containing 3
NMT2 N-myristoyltransferase 2
NR4A1 nuclear receptor subfamily 4, group A, member 1
NUCB1 nucleobindin 1
OCRL oculocerebrorenal syndrome of Lowe
OLAH oleoyl-ACP hydrolase
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)
PER1 period circadian clock 1
PKD2L1 polycystic kidney disease 2-like 1
PMM2 phosphomannomutase 2
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RHOB ras homolog family member B
RHOH ras homolog family member H
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SAP30 Sin3A-associated protein, 30kDa
SDC2 syndecan 2
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SIDT2 SID1 transmembrane family, member 2
SLC35E3 solute carrier family 35, member E3
SLCO4A1 solute carrier organic anion transporter family, member 4A1
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
TBXA2R thromboxane A2 receptor
THBS1 thrombospondin 1
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TLR2 toll-like receptor 2
TMBIM1 transmembrane BAX inhibitor motif containing 1
TPRA1 transmembrane protein, adipocyte asscociated 1
TPST1 tyrosylprotein sulfotransferase 1
TRAPPC9 trafficking protein particle complex 9
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TSC22D3 TSC22 domain family, member 3
TTR transthyretin
USP34 ubiquitin specific peptidase 34
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
ZBTB16 zinc finger and BTB domain containing 16
ZFP36L2 ZFP36 ring finger protein-like 2

decreased expression

Symbol Name
ACVR1 activin A receptor, type I
ACYP1 acylphosphatase 1, erythrocyte (common) type
ANXA3 annexin A3
APH1B APH1B gamma secretase subunit
ARID4A AT rich interactive domain 4A (RBP1-like)
BBC3 BCL2 binding component 3
BCL7C B-cell CLL/lymphoma 7C
BRIX1 BRX1, biogenesis of ribosomes
C17ORF70 chromosome 17 open reading frame 70
C1QTNF1 C1q and tumor necrosis factor related protein 1
C6ORF47 chromosome 6 open reading frame 47
CARM1 coactivator-associated arginine methyltransferase 1
CASZ1 castor zinc finger 1
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CCL2 chemokine (C-C motif) ligand 2
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLCN6 chloride channel, voltage-sensitive 6
COL4A3BP collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
CRIPT cysteine-rich PDZ-binding protein
CXCL8 chemokine (C-X-C motif) ligand 8
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DIXDC1 DIX domain containing 1
DMBT1 deleted in malignant brain tumors 1
DRD5 dopamine receptor D5
DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1
DYNLL1 dynein, light chain, LC8-type 1
ECD ecdysoneless homolog (Drosophila)
EGR2 early growth response 2
ERF Ets2 repressor factor
FAM179B family with sequence similarity 179, member B
FGL1 fibrinogen-like 1
FUCA1 fucosidase, alpha-L- 1, tissue
GALR3 galanin receptor 3
GDAP2 ganglioside induced differentiation associated protein 2
GMCL1 germ cell-less, spermatogenesis associated 1
GP1BA glycoprotein Ib (platelet), alpha polypeptide
GPR18 G protein-coupled receptor 18
GSTA4 glutathione S-transferase alpha 4
HCAR3 hydroxycarboxylic acid receptor 3
HDAC3 histone deacetylase 3
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
INO80D INO80 complex subunit D
JADE1 jade family PHD finger 1
KIAA0753 KIAA0753
KIAA0894 KIAA0894 protein
KIF23 kinesin family member 23
KIF3B kinesin family member 3B
LIMD2 LIM domain containing 2
LRRK1 leucine-rich repeat kinase 1
LSM1 LSM1, U6 small nuclear RNA associated
LSP1 lymphocyte-specific protein 1
LUC7L LUC7-like (S. cerevisiae)
MBTD1 mbt domain containing 1
MFSD12 major facilitator superfamily domain containing 12
MRPL19 mitochondrial ribosomal protein L19
MYD88 myeloid differentiation primary response 88
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
NFE2 nuclear factor, erythroid 2
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1
PAQR4 progestin and adipoQ receptor family member IV
PARP12 poly (ADP-ribose) polymerase family, member 12
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PLA2G12A phospholipase A2, group XIIA
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
PRKRIP1 PRKR interacting protein 1 (IL11 inducible)
PSKH1 protein serine kinase H1
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1
RGS13 regulator of G-protein signaling 13
RGS2 regulator of G-protein signaling 2
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RIN1 Ras and Rab interactor 1
RNF11 ring finger protein 11
RNH1 ribonuclease/angiogenin inhibitor 1
RPGR retinitis pigmentosa GTPase regulator
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SH3GL1 SH3-domain GRB2-like 1
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5
SNRNP35 small nuclear ribonucleoprotein 35kDa (U11/U12)
STAG3 stromal antigen 3
STRA13 stimulated by retinoic acid 13
TEX30 testis expressed 30
TMEM14A transmembrane protein 14A
TMEM158 transmembrane protein 158 (gene/pseudogene)
TNF tumor necrosis factor
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TSPYL2 TSPY-like 2
TTBK2 tau tubulin kinase 2
TTPAL tocopherol (alpha) transfer protein-like
TULP4 tubby like protein 4
TXLNA taxilin alpha
UBE3C ubiquitin protein ligase E3C
WBSCR16 Williams-Beuren syndrome chromosome region 16
WT1-AS WT1 antisense RNA
XAF1 XIAP associated factor 1
ZBTB48 zinc finger and BTB domain containing 48
ZCCHC8 zinc finger, CCHC domain containing 8