budesonide-6330 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the budesonide-6330 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD2 abhydrolase domain containing 2
ADARB1 adenosine deaminase, RNA-specific, B1
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ARHGAP28 Rho GTPase activating protein 28
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARID1A AT rich interactive domain 1A (SWI-like)
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
BBC3 BCL2 binding component 3
CDC25A cell division cycle 25A
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal)
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CNKSR2 connector enhancer of kinase suppressor of Ras 2
CNOT4 CCR4-NOT transcription complex, subunit 4
COL2A1 collagen, type II, alpha 1
COL8A1 collagen, type VIII, alpha 1
DHRS9 dehydrogenase/reductase (SDR family) member 9
DSTYK dual serine/threonine and tyrosine protein kinase
DTNA dystrobrevin, alpha
DUSP1 dual specificity phosphatase 1
ECE1 endothelin converting enzyme 1
EFNB2 ephrin-B2
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2
FOSL2 FOS-like antigen 2
GATA2 GATA binding protein 2
GP2 glycoprotein 2 (zymogen granule membrane)
HCFC1 host cell factor C1
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
IKZF5 IKAROS family zinc finger 5 (Pegasus)
IL17RB interleukin 17 receptor B
KCTD13 potassium channel tetramerization domain containing 13
KIAA1467 KIAA1467
LAMC2 laminin, gamma 2
MAPK7 mitogen-activated protein kinase 7
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MIIP migration and invasion inhibitory protein
MT1X metallothionein 1X
NAV2 neuron navigator 2
NDUFA2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa
NF1 neurofibromin 1
NNMT nicotinamide N-methyltransferase
NOL10 nucleolar protein 10
NOX1 NADPH oxidase 1
NR4A1 nuclear receptor subfamily 4, group A, member 1
NRP2 neuropilin 2
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6
NUMA1 nuclear mitotic apparatus protein 1
OSBPL10 oxysterol binding protein-like 10
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PDE4DIP phosphodiesterase 4D interacting protein
PDLIM7 PDZ and LIM domain 7 (enigma)
PER1 period circadian clock 1
PHF14 PHD finger protein 14
PIPOX pipecolic acid oxidase
PLAT plasminogen activator, tissue
PLCH1 phospholipase C, eta 1
PMS2P2 postmeiotic segregation increased 2 pseudogene 2
POLL polymerase (DNA directed), lambda
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PTBP3 polypyrimidine tract binding protein 3
RAB36 RAB36, member RAS oncogene family
RAD50 RAD50 homolog (S. cerevisiae)
RBM48 RNA binding motif protein 48
RHOBTB2 Rho-related BTB domain containing 2
RUNX1-IT1 RUNX1 intronic transcript 1
SCAND2P SCAN domain containing 2 pseudogene
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
SERPINB13 serpin peptidase inhibitor, clade B (ovalbumin), member 13
SETD8 SET domain containing (lysine methyltransferase) 8
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC22A14 solute carrier family 22, member 14
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLITRK5 SLIT and NTRK-like family, member 5
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SORCS3 sortilin-related VPS10 domain containing receptor 3
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
SRD5A3 steroid 5 alpha-reductase 3
SS18 synovial sarcoma translocation, chromosome 18
STBD1 starch binding domain 1
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
TEF thyrotrophic embryonic factor
THBS1 thrombospondin 1
TIMELESS timeless circadian clock
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TNFRSF9 tumor necrosis factor receptor superfamily, member 9
TPP1 tripeptidyl peptidase I
UHRF1BP1L UHRF1 binding protein 1-like
UNC119 unc-119 homolog (C. elegans)
USB1 U6 snRNA biogenesis 1
WDR33 WD repeat domain 33
ZNF205 zinc finger protein 205
ZNF384 zinc finger protein 384
ZNF492 zinc finger protein 492

decreased expression

Symbol Name
AARS alanyl-tRNA synthetase
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
AFAP1 actin filament associated protein 1
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ARL15 ADP-ribosylation factor-like 15
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
BCORL1 BCL6 corepressor-like 1
BOLA1 bolA family member 1
C11ORF63 chromosome 11 open reading frame 63
CBR4 carbonyl reductase 4
CBX7 chromobox homolog 7
CCDC94 coiled-coil domain containing 94
CHPF chondroitin polymerizing factor
CLEC2B C-type lectin domain family 2, member B
CORO2A coronin, actin binding protein, 2A
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DYSF dysferlin
EFTUD1 elongation factor Tu GTP binding domain containing 1
EHD3 EH-domain containing 3
ELP3 elongator acetyltransferase complex subunit 3
EPPK1 epiplakin 1
ERN2 endoplasmic reticulum to nucleus signaling 2
FUZ fuzzy planar cell polarity protein
FZD8 frizzled class receptor 8
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GLTSCR1 glioma tumor suppressor candidate region gene 1
GPATCH2 G patch domain containing 2
GRAMD3 GRAM domain containing 3
HDAC9 histone deacetylase 9
HIRA histone cell cycle regulator
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IL1B interleukin 1, beta
IL7R interleukin 7 receptor
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
IRF1 interferon regulatory factor 1
KDM5C lysine (K)-specific demethylase 5C
KIF3A kinesin family member 3A
KRI1 KRI1 homolog (S. cerevisiae)
LUC7L LUC7-like (S. cerevisiae)
LYPD1 LY6/PLAUR domain containing 1
MAPKAP1 mitogen-activated protein kinase associated protein 1
MBIP MAP3K12 binding inhibitory protein 1
MED15 mediator complex subunit 15
MRPL28 mitochondrial ribosomal protein L28
MRPL41 mitochondrial ribosomal protein L41
NOTCH1 notch 1
NR3C2 nuclear receptor subfamily 3, group C, member 2
NRSN2 neurensin 2
PARD6A par-6 family cell polarity regulator alpha
PCID2 PCI domain containing 2
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PDXDC1 pyridoxal-dependent decarboxylase domain containing 1
PEX13 peroxisomal biogenesis factor 13
PIGL phosphatidylinositol glycan anchor biosynthesis, class L
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PLAU plasminogen activator, urokinase
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
POLR2J2 polymerase (RNA) II (DNA directed) polypeptide J2
PPL periplakin
PRR3 proline rich 3
PTPN9 protein tyrosine phosphatase, non-receptor type 9
PYCRL pyrroline-5-carboxylate reductase-like
RAB4B RAB4B, member RAS oncogene family
RASA2 RAS p21 protein activator 2
RIBC2 RIB43A domain with coiled-coils 2
RIN1 Ras and Rab interactor 1
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RPUSD2 RNA pseudouridylate synthase domain containing 2
SATB1 SATB homeobox 1
SH2D4A SH2 domain containing 4A
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae)
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC25A40 solute carrier family 25, member 40
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3
SLC35G2 solute carrier family 35, member G2
SLC46A3 solute carrier family 46, member 3
SLMO1 slowmo homolog 1 (Drosophila)
SNPH syntaphilin
STAG3 stromal antigen 3
TENM4 teneurin transmembrane protein 4
TMEM156 transmembrane protein 156
TMEM183A transmembrane protein 183A
TRIM45 tripartite motif containing 45
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
ZNF177 zinc finger protein 177
ZNF324 zinc finger protein 324
ZNF331 zinc finger protein 331
ZNF34 zinc finger protein 34
ZNF528 zinc finger protein 528
ZNF668 zinc finger protein 668
ZNF747 zinc finger protein 747
ZXDC ZXD family zinc finger C