bufexamac-2382 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the bufexamac-2382 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
ALOX5 arachidonate 5-lipoxygenase
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
ATG10 autophagy related 10
AURKA aurora kinase A
BTD biotinidase
C11ORF16 chromosome 11 open reading frame 16
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit
CD58 CD58 molecule
CD59 CD59 molecule, complement regulatory protein
CD84 CD84 molecule
CDC25C cell division cycle 25C
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CDKL3 cyclin-dependent kinase-like 3
COL13A1 collagen, type XIII, alpha 1
CPN2 carboxypeptidase N, polypeptide 2
CRIP1 cysteine-rich protein 1 (intestinal)
CYP2A7 cytochrome P450, family 2, subfamily A, polypeptide 7
DGKA diacylglycerol kinase, alpha 80kDa
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
DOCK10 dedicator of cytokinesis 10
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
FERMT1 fermitin family member 1
FLRT2 fibronectin leucine rich transmembrane protein 2
GADD45GIP1 growth arrest and DNA-damage-inducible, gamma interacting protein 1
GALNT10 polypeptide N-acetylgalactosaminyltransferase 10
GALNT2 polypeptide N-acetylgalactosaminyltransferase 2
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5
GLRA1 glycine receptor, alpha 1
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GSTTP1 glutathione S-transferase theta pseudogene 1
HDAC7 histone deacetylase 7
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HOMER3 homer scaffolding protein 3
HPSE heparanase
HYAL1 hyaluronoglucosaminidase 1
ICA1 islet cell autoantigen 1, 69kDa
IL1R2 interleukin 1 receptor, type II
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KHK ketohexokinase (fructokinase)
KLF3 Kruppel-like factor 3 (basic)
KMT2A lysine (K)-specific methyltransferase 2A
KRT8P12 keratin 8 pseudogene 12
LIN7A lin-7 homolog A (C. elegans)
LOC100131510 uncharacterized LOC100131510
MAOA monoamine oxidase A
MDFI MyoD family inhibitor
MIOS missing oocyte, meiosis regulator, homolog (Drosophila)
MMP24 matrix metallopeptidase 24 (membrane-inserted)
MRPS18C mitochondrial ribosomal protein S18C
MTUS1 microtubule associated tumor suppressor 1
MYF5 myogenic factor 5
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NBR2 neighbor of BRCA1 gene 2 (non-protein coding)
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain)
NOTCH4 notch 4
NOX5 NADPH oxidase, EF-hand calcium binding domain 5
NPR1 natriuretic peptide receptor 1
NR6A1 nuclear receptor subfamily 6, group A, member 1
OAZ3 ornithine decarboxylase antizyme 3
OPRL1 opiate receptor-like 1
PHC1 polyhomeotic homolog 1 (Drosophila)
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
PRSS22 protease, serine, 22
PRX periaxin
PTGDR2 prostaglandin D2 receptor 2
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PYGB phosphorylase, glycogen; brain
RASAL2 RAS protein activator like 2
RHBDD3 rhomboid domain containing 3
RHEB Ras homolog enriched in brain
ROBO4 roundabout, axon guidance receptor, homolog 4 (Drosophila)
RQCD1 RCD1 required for cell differentiation1 homolog (S. pombe)
RRBP1 ribosome binding protein 1
SAPCD1 suppressor APC domain containing 1
SERHL2 serine hydrolase-like 2
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SIGLEC7 sialic acid binding Ig-like lectin 7
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC35F6 solute carrier family 35, member F6
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SNX13 sorting nexin 13
SPARCL1 SPARC-like 1 (hevin)
SPN sialophorin
ST14 suppression of tumorigenicity 14 (colon carcinoma)
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
STAB2 stabilin 2
STAT2 signal transducer and activator of transcription 2, 113kDa
STBD1 starch binding domain 1
STX1A syntaxin 1A (brain)
T T, brachyury homolog (mouse)
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TTC38 tetratricopeptide repeat domain 38
VPS9D1 VPS9 domain containing 1
ZBTB33 zinc finger and BTB domain containing 33
ZFP64 ZFP64 zinc finger protein

decreased expression

Symbol Name
ACP2 acid phosphatase 2, lysosomal
ACVR2A activin A receptor, type IIA
ACYP2 acylphosphatase 2, muscle type
ADTRP androgen-dependent TFPI-regulating protein
AHDC1 AT hook, DNA binding motif, containing 1
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANKRD40 ankyrin repeat domain 40
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
ARF5 ADP-ribosylation factor 5
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
ARNTL2 aryl hydrocarbon receptor nuclear translocator-like 2
ATP10D ATPase, class V, type 10D
AVPI1 arginine vasopressin-induced 1
BCORL1 BCL6 corepressor-like 1
BTBD7 BTB (POZ) domain containing 7
BZRAP1 benzodiazepine receptor (peripheral) associated protein 1
C14ORF93 chromosome 14 open reading frame 93
C7ORF43 chromosome 7 open reading frame 43
CASP7 caspase 7, apoptosis-related cysteine peptidase
CCDC85C coiled-coil domain containing 85C
CCNJ cyclin J
CD1D CD1d molecule
CDK6 cyclin-dependent kinase 6
CDR2L cerebellar degeneration-related protein 2-like
CECR1 cat eye syndrome chromosome region, candidate 1
CIC capicua transcriptional repressor
CIDEC cell death-inducing DFFA-like effector c
CLCN6 chloride channel, voltage-sensitive 6
CPNE7 copine VII
CPTP ceramide-1-phosphate transfer protein
CXCR2 chemokine (C-X-C motif) receptor 2
DDN dendrin
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila)
DNAJC13 DnaJ (Hsp40) homolog, subfamily C, member 13
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EXD3 exonuclease 3'-5' domain containing 3
FAM50B family with sequence similarity 50, member B
FBRS fibrosin
FCHO1 FCH domain only 1
FLCN folliculin
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GRIP2 glutamate receptor interacting protein 2
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HIST1H4C histone cluster 1, H4c
IFT81 intraflagellar transport 81
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
IRF9 interferon regulatory factor 9
JUNB jun B proto-oncogene
KDM5C lysine (K)-specific demethylase 5C
KIF1B kinesin family member 1B
LIG4 ligase IV, DNA, ATP-dependent
LRP5 low density lipoprotein receptor-related protein 5
MBIP MAP3K12 binding inhibitory protein 1
MBTD1 mbt domain containing 1
MEGF8 multiple EGF-like-domains 8
METTL2B methyltransferase like 2B
MRPL44 mitochondrial ribosomal protein L44
MTA2 metastasis associated 1 family, member 2
MXD3 MAX dimerization protein 3
NIPAL2 NIPA-like domain containing 2
OCEL1 occludin/ELL domain containing 1
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
PAQR6 progestin and adipoQ receptor family member VI
PGPEP1 pyroglutamyl-peptidase I
PRKG2 protein kinase, cGMP-dependent, type II
PYCRL pyrroline-5-carboxylate reductase-like
RNF19B ring finger protein 19B
SCAI suppressor of cancer cell invasion
SCAMP4 secretory carrier membrane protein 4
SCD5 stearoyl-CoA desaturase 5
SGMS1 sphingomyelin synthase 1
SIRT1 sirtuin 1
SLC22A14 solute carrier family 22, member 14
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLITRK5 SLIT and NTRK-like family, member 5
SLPI secretory leukocyte peptidase inhibitor
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SPATS2 spermatogenesis associated, serine-rich 2
SREBF1 sterol regulatory element binding transcription factor 1
STXBP1 syntaxin binding protein 1
TCTN2 tectonic family member 2
TEC tec protein tyrosine kinase
TESK1 testis-specific kinase 1
TET3 tet methylcytosine dioxygenase 3
TMEM109 transmembrane protein 109
TMEM184B transmembrane protein 184B
TMEM209 transmembrane protein 209
TNRC6B trinucleotide repeat containing 6B
TSPAN13 tetraspanin 13
USB1 U6 snRNA biogenesis 1
USP6 ubiquitin specific peptidase 6
ZC2HC1A zinc finger, C2HC-type containing 1A
ZNF222 zinc finger protein 222
ZNF696 zinc finger protein 696