| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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200 genes differentially expressed following the bufexamac-5090 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA2 | ATP-binding cassette, sub-family A (ABC1), member 2 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) |
| AGTR2 | angiotensin II receptor, type 2 |
| AKAP7 | A kinase (PRKA) anchor protein 7 |
| ALK | anaplastic lymphoma receptor tyrosine kinase |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein |
| C14ORF93 | chromosome 14 open reading frame 93 |
| C9ORF156 | chromosome 9 open reading frame 156 |
| CCDC181 | coiled-coil domain containing 181 |
| CD82 | CD82 molecule |
| CHRNG | cholinergic receptor, nicotinic, gamma (muscle) |
| CLEC1B | C-type lectin domain family 1, member B |
| CLIC3 | chloride intracellular channel 3 |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| CSHL1 | chorionic somatomammotropin hormone-like 1 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| DACH1 | dachshund family transcription factor 1 |
| DAPK2 | death-associated protein kinase 2 |
| DCC | DCC netrin 1 receptor |
| ELOVL5 | ELOVL fatty acid elongase 5 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FAM212B | family with sequence similarity 212, member B |
| FOXO4 | forkhead box O4 |
| FRMPD1 | FERM and PDZ domain containing 1 |
| FXYD2 | FXYD domain containing ion transport regulator 2 |
| GRB7 | growth factor receptor-bound protein 7 |
| GRTP1 | growth hormone regulated TBC protein 1 |
| GYG2 | glycogenin 2 |
| HIST1H2BN | histone cluster 1, H2bn |
| HOXB1 | homeobox B1 |
| HOXB5 | homeobox B5 |
| HPR | haptoglobin-related protein |
| ICA1 | islet cell autoantigen 1, 69kDa |
| IL6 | interleukin 6 |
| KIAA1456 | KIAA1456 |
| KIF5C | kinesin family member 5C |
| KLRG1 | killer cell lectin-like receptor subfamily G, member 1 |
| KSR1 | kinase suppressor of ras 1 |
| LAT2 | linker for activation of T cells family, member 2 |
| LEFTY2 | left-right determination factor 2 |
| LILRA4 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4 |
| LOC100129648 | uncharacterized LOC100129648 |
| LOC284244 | uncharacterized LOC284244 |
| MAP3K7CL | MAP3K7 C-terminal like |
| MAPRE3 | microtubule-associated protein, RP/EB family, member 3 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) |
| MPZ | myelin protein zero |
| MRPS18C | mitochondrial ribosomal protein S18C |
| MSL3 | male-specific lethal 3 homolog (Drosophila) |
| MTMR3 | myotubularin related protein 3 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming |
| NACAD | NAC alpha domain containing |
| NCR2 | natural cytotoxicity triggering receptor 2 |
| NDUFAF5 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 5 |
| NRG1 | neuregulin 1 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa |
| OMD | osteomodulin |
| OR2B6 | olfactory receptor, family 2, subfamily B, member 6 |
| PACRG | PARK2 co-regulated |
| PAX2 | paired box 2 |
| PCDHB17P | protocadherin beta 17 pseudogene |
| PDE4B | phosphodiesterase 4B, cAMP-specific |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 |
| PIP | prolactin-induced protein |
| PML | promyelocytic leukemia |
| PRB1 | proline-rich protein BstNI subfamily 1 |
| PRB4 | proline-rich protein BstNI subfamily 4 |
| PRDM2 | PR domain containing 2, with ZNF domain |
| PROL1 | proline rich, lacrimal 1 |
| PSG1 | pregnancy specific beta-1-glycoprotein 1 |
| PTEN | phosphatase and tensin homolog |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 |
| PTPRH | protein tyrosine phosphatase, receptor type, H |
| QPCTL | glutaminyl-peptide cyclotransferase-like |
| RAB11FIP3 | RAB11 family interacting protein 3 (class II) |
| RGS5 | regulator of G-protein signaling 5 |
| RPS3A | ribosomal protein S3A |
| SEC24D | SEC24 family member D |
| SEMA6A | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A |
| SIT1 | signaling threshold regulating transmembrane adaptor 1 |
| SORBS2 | sorbin and SH3 domain containing 2 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 |
| SRGAP3 | SLIT-ROBO Rho GTPase activating protein 3 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| TAS2R1 | taste receptor, type 2, member 1 |
| TBL2 | transducin (beta)-like 2 |
| TBXA2R | thromboxane A2 receptor |
| TCL6 | T-cell leukemia/lymphoma 6 (non-protein coding) |
| TCP11 | t-complex 11, testis-specific |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TOP3B | topoisomerase (DNA) III beta |
| TRD | T cell receptor delta locus |
| TRPC1 | transient receptor potential cation channel, subfamily C, member 1 |
| TTC30A | tetratricopeptide repeat domain 30A |
| UBA6 | ubiquitin-like modifier activating enzyme 6 |
| UPF3A | UPF3 regulator of nonsense transcripts homolog A (yeast) |
| ZC3H7B | zinc finger CCCH-type containing 7B |
| ZMYND8 | zinc finger, MYND-type containing 8 |
| Symbol | Name |
|---|---|
| ADRB2 | adrenoceptor beta 2, surface |
| ALKBH4 | alkB, alkylation repair homolog 4 (E. coli) |
| ANXA2P3 | annexin A2 pseudogene 3 |
| ATAD5 | ATPase family, AAA domain containing 5 |
| C7ORF69 | chromosome 7 open reading frame 69 |
| CASD1 | CAS1 domain containing 1 |
| CCDC47 | coiled-coil domain containing 47 |
| CCZ1B | CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae) |
| CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 |
| CGREF1 | cell growth regulator with EF-hand domain 1 |
| CLDN11 | claudin 11 |
| CLEC16A | C-type lectin domain family 16, member A |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| CPA4 | carboxypeptidase A4 |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 |
| CTGF | connective tissue growth factor |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DENND4A | DENN/MADD domain containing 4A |
| DNAJC17 | DnaJ (Hsp40) homolog, subfamily C, member 17 |
| DNMBP | dynamin binding protein |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 |
| FAM114A2 | family with sequence similarity 114, member A2 |
| FAM50B | family with sequence similarity 50, member B |
| FRS2 | fibroblast growth factor receptor substrate 2 |
| GABPA | GA binding protein transcription factor, alpha subunit 60kDa |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| GNAZ | guanine nucleotide binding protein (G protein), alpha z polypeptide |
| GPR3 | G protein-coupled receptor 3 |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| GRPR | gastrin-releasing peptide receptor |
| GTF2I | general transcription factor IIi |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| HIRA | histone cell cycle regulator |
| HIST1H2AM | histone cluster 1, H2am |
| HOXA1 | homeobox A1 |
| HOXA4 | homeobox A4 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| IFNAR1 | interferon (alpha, beta and omega) receptor 1 |
| IL15RA | interleukin 15 receptor, alpha |
| INF2 | inverted formin, FH2 and WH2 domain containing |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KCTD15 | potassium channel tetramerization domain containing 15 |
| KIAA1462 | KIAA1462 |
| KLF2 | Kruppel-like factor 2 |
| KLHL28 | kelch-like family member 28 |
| KLK6 | kallikrein-related peptidase 6 |
| LANCL2 | LanC lantibiotic synthetase component C-like 2 (bacterial) |
| LOC390998 | ribosomal protein L10 pseudogene |
| LRIG2 | leucine-rich repeats and immunoglobulin-like domains 2 |
| LRRC61 | leucine rich repeat containing 61 |
| LYRM2 | LYR motif containing 2 |
| MAP3K6 | mitogen-activated protein kinase kinase kinase 6 |
| MED24 | mediator complex subunit 24 |
| MEIS3P1 | Meis homeobox 3 pseudogene 1 |
| METTL16 | methyltransferase like 16 |
| MFGE8 | milk fat globule-EGF factor 8 protein |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 |
| MKS1 | Meckel syndrome, type 1 |
| NABP1 | nucleic acid binding protein 1 |
| NDP | Norrie disease (pseudoglioma) |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| PARM1 | prostate androgen-regulated mucin-like protein 1 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 |
| PEG3 | paternally expressed 3 |
| PLD3 | phospholipase D family, member 3 |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 |
| PPCS | phosphopantothenoylcysteine synthetase |
| PTK6 | protein tyrosine kinase 6 |
| PTPRS | protein tyrosine phosphatase, receptor type, S |
| PTX3 | pentraxin 3, long |
| PXDC1 | PX domain containing 1 |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 |
| RECQL4 | RecQ protein-like 4 |
| RIN1 | Ras and Rab interactor 1 |
| RPGR | retinitis pigmentosa GTPase regulator |
| RRN3 | RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae) |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SH2D4A | SH2 domain containing 4A |
| SLC39A1 | solute carrier family 39 (zinc transporter), member 1 |
| SMAD7 | SMAD family member 7 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| STEAP4 | STEAP family member 4 |
| STIM1 | stromal interaction molecule 1 |
| TNFSF13 | tumor necrosis factor (ligand) superfamily, member 13 |
| TOR3A | torsin family 3, member A |
| TUBA3C | tubulin, alpha 3c |
| TUBGCP5 | tubulin, gamma complex associated protein 5 |
| TWISTNB | TWIST neighbor |
| VRK2 | vaccinia related kinase 2 |
| WDR18 | WD repeat domain 18 |
| WDR33 | WD repeat domain 33 |
| WDR43 | WD repeat domain 43 |
| WDR6 | WD repeat domain 6 |
| WNT7A | wingless-type MMTV integration site family, member 7A |
| ZNF354A | zinc finger protein 354A |
| ZNF606 | zinc finger protein 606 |
| ZNF668 | zinc finger protein 668 |
| ZNHIT2 | zinc finger, HIT-type containing 2 |
