bufexamac Gene Set

Dataset LINCS L1000 CMAP Chemical Perturbation Consensus Signatures
Category transcriptomics
Type small molecule perturbation
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Genes

22 genes differentially expressed following the bufexamac small molecule perturbation from the LINCS L1000 CMAP Chemical Perturbation Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
PRPF18 pre-mRNA processing factor 18 3.56739
RPRM reprimo, TP53 dependent G2 arrest mediator candidate 3.40017
RPP38 ribonuclease P/MRP 38kDa subunit 3.30745
CALCA calcitonin-related polypeptide alpha 3.23166
MDFIC MyoD family inhibitor domain containing 3.19195
KIF1A kinesin family member 1A 3.16416
ACAT2 acetyl-CoA acetyltransferase 2 3.13005
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 3.10297
MPDZ multiple PDZ domain protein 3.06854
FMO4 flavin containing monooxygenase 4 3.00151

decreased expression

Symbol Name Standardized Value
MAP7 microtubule-associated protein 7 -3.87278
TSPAN4 tetraspanin 4 -3.8226
E2F2 E2F transcription factor 2 -3.62436
BEGAIN brain-enriched guanylate kinase-associated -3.59826
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B -3.57492
CSRP1 cysteine and glycine-rich protein 1 -3.4283
KNTC1 kinetochore associated 1 -3.20975
CDC25B cell division cycle 25B -3.15243
RPL10L ribosomal protein L10-like -3.11919
PREB prolactin regulatory element binding -3.08652
SEPTIN4 septin 4 -3.0515
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -3.03743