buflomedil-1338 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the buflomedil-1338 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABAT 4-aminobutyrate aminotransferase
ARHGAP44 Rho GTPase activating protein 44
ATPAF2 ATP synthase mitochondrial F1 complex assembly factor 2
B3GAT3 beta-1,3-glucuronyltransferase 3
BCL2L1 BCL2-like 1
BNIP1 BCL2/adenovirus E1B 19kDa interacting protein 1
BPI bactericidal/permeability-increasing protein
BRAF B-Raf proto-oncogene, serine/threonine kinase
C16ORF58 chromosome 16 open reading frame 58
C16ORF59 chromosome 16 open reading frame 59
CACFD1 calcium channel flower domain containing 1
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta
CASP10 caspase 10, apoptosis-related cysteine peptidase
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4
CDCP1 CUB domain containing protein 1
CENPT centromere protein T
CHD3 chromodomain helicase DNA binding protein 3
COX15 cytochrome c oxidase assembly homolog 15 (yeast)
CYB561 cytochrome b561
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
DAXX death-domain associated protein
DDAH2 dimethylarginine dimethylaminohydrolase 2
DEAF1 DEAF1 transcription factor
DTX2 deltex 2, E3 ubiquitin ligase
DUS4L dihydrouridine synthase 4-like (S. cerevisiae)
ELMO3 engulfment and cell motility 3
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
ERCC2 excision repair cross-complementation group 2
FLRT1 fibronectin leucine rich transmembrane protein 1
FOXO1 forkhead box O1
FUZ fuzzy planar cell polarity protein
FYB FYN binding protein
GATA2 GATA binding protein 2
GSK3A glycogen synthase kinase 3 alpha
HCFC1R1 host cell factor C1 regulator 1 (XPO1 dependent)
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
INO80B INO80 complex subunit B
INO80D INO80 complex subunit D
ISOC2 isochorismatase domain containing 2
IZUMO4 IZUMO family member 4
JMJD4 jumonji domain containing 4
KLHL28 kelch-like family member 28
LDB1 LIM domain binding 1
LOC729164 hCG1732469
MAGED2 melanoma antigen family D2
MCTP2 multiple C2 domains, transmembrane 2
MRPL2 mitochondrial ribosomal protein L2
MSRB2 methionine sulfoxide reductase B2
MYOF myoferlin
NCDN neurochondrin
NCLN nicalin
NCS1 neuronal calcium sensor 1
NLRP1 NLR family, pyrin domain containing 1
NPR2 natriuretic peptide receptor 2
NR2F6 nuclear receptor subfamily 2, group F, member 6
OGG1 8-oxoguanine DNA glycosylase
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
OSBPL2 oxysterol binding protein-like 2
PACS2 phosphofurin acidic cluster sorting protein 2
PAOX polyamine oxidase (exo-N4-amino)
PCGF3 polycomb group ring finger 3
PITRM1 pitrilysin metallopeptidase 1
POLL polymerase (DNA directed), lambda
QTRT1 queuine tRNA-ribosyltransferase 1
RAB11FIP3 RAB11 family interacting protein 3 (class II)
RASAL2 RAS protein activator like 2
RC3H2 ring finger and CCCH-type domains 2
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RNF40 ring finger protein 40, E3 ubiquitin protein ligase
RPAP2 RNA polymerase II associated protein 2
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
RUNX1 runt-related transcription factor 1
RUSC2 RUN and SH3 domain containing 2
SAMD4A sterile alpha motif domain containing 4A
SEMA3G sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G
SENP3 SUMO1/sentrin/SMT3 specific peptidase 3
SFTPB surfactant protein B
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
SMARCD1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
SMYD2 SET and MYND domain containing 2
SOX12 SRY (sex determining region Y)-box 12
SPATA2 spermatogenesis associated 2
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive)
SUN1 Sad1 and UNC84 domain containing 1
TCTN1 tectonic family member 1
TEC tec protein tyrosine kinase
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TTLL3 tubulin tyrosine ligase-like family member 3
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
ZDHHC14 zinc finger, DHHC-type containing 14
ZNF250 zinc finger protein 250
ZNF37BP zinc finger protein 37B, pseudogene
ZNF473 zinc finger protein 473
ZNF609 zinc finger protein 609
ZNF821 zinc finger protein 821

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ACPP acid phosphatase, prostate
ACVR2B activin A receptor, type IIB
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
AIM1 absent in melanoma 1
ANKFY1 ankyrin repeat and FYVE domain containing 1
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BAHD1 bromo adjacent homology domain containing 1
BAK1 BCL2-antagonist/killer 1
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin)
BST1 bone marrow stromal cell antigen 1
C11ORF21 chromosome 11 open reading frame 21
C11ORF30 chromosome 11 open reading frame 30
C14ORF159 chromosome 14 open reading frame 159
C8ORF33 chromosome 8 open reading frame 33
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CBX7 chromobox homolog 7
CCDC69 coiled-coil domain containing 69
CCL2 chemokine (C-C motif) ligand 2
CD3D CD3d molecule, delta (CD3-TCR complex)
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CEP131 centrosomal protein 131kDa
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DHRS3 dehydrogenase/reductase (SDR family) member 3
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DSE dermatan sulfate epimerase
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
EMD emerin
EPHB6 EPH receptor B6
EXOC5 exocyst complex component 5
FAM184A family with sequence similarity 184, member A
FAM63A family with sequence similarity 63, member A
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FGL2 fibrinogen-like 2
FKBP9 FK506 binding protein 9, 63 kDa
FLCN folliculin
GTF2H2B general transcription factor IIH, polypeptide 2B (pseudogene)
GTF2I general transcription factor IIi
GUF1 GUF1 GTPase homolog (S. cerevisiae)
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HYAL3 hyaluronoglucosaminidase 3
IFI30 interferon, gamma-inducible protein 30
IL24 interleukin 24
INF2 inverted formin, FH2 and WH2 domain containing
IRF2 interferon regulatory factor 2
KDM5C lysine (K)-specific demethylase 5C
KLF13 Kruppel-like factor 13
LIG4 ligase IV, DNA, ATP-dependent
LIN7A lin-7 homolog A (C. elegans)
LLGL2 lethal giant larvae homolog 2 (Drosophila)
LY96 lymphocyte antigen 96
MBTD1 mbt domain containing 1
MICALL2 MICAL-like 2
MYL5 myosin, light chain 5, regulatory
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NPFFR1 neuropeptide FF receptor 1
NR1H3 nuclear receptor subfamily 1, group H, member 3
PEX26 peroxisomal biogenesis factor 26
POLM polymerase (DNA directed), mu
PSKH1 protein serine kinase H1
PTPN4 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
RAB23 RAB23, member RAS oncogene family
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RHOBTB1 Rho-related BTB domain containing 1
RINT1 RAD50 interactor 1
RNF146 ring finger protein 146
RNF25 ring finger protein 25
RRP1 ribosomal RNA processing 1
SAMD9 sterile alpha motif domain containing 9
SGMS1 sphingomyelin synthase 1
SLC25A40 solute carrier family 25, member 40
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9
SLC38A6 solute carrier family 38, member 6
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
STBD1 starch binding domain 1
STK16 serine/threonine kinase 16
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TET3 tet methylcytosine dioxygenase 3
THBS3 thrombospondin 3
TJP2 tight junction protein 2
TMBIM1 transmembrane BAX inhibitor motif containing 1
TMEM230 transmembrane protein 230
TOLLIP toll interacting protein
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRMT12 tRNA methyltransferase 12 homolog (S. cerevisiae)
TXLNG taxilin gamma
UBQLN4 ubiquilin 4
UNKL unkempt family zinc finger-like
ZC2HC1A zinc finger, C2HC-type containing 1A
ZMAT5 zinc finger, matrin-type 5
ZNF14 zinc finger protein 14
ZNF253 zinc finger protein 253
ZNF35 zinc finger protein 35
ZNF747 zinc finger protein 747
ZNF787 zinc finger protein 787