buflomedil-3274 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the buflomedil-3274 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A1CF APOBEC1 complementation factor
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ADAM28 ADAM metallopeptidase domain 28
ADGRL1 adhesion G protein-coupled receptor L1
ALG12 ALG12, alpha-1,6-mannosyltransferase
ANGEL2 angel homolog 2 (Drosophila)
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
ATP7A ATPase, Cu++ transporting, alpha polypeptide
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CD58 CD58 molecule
CLCF1 cardiotrophin-like cytokine factor 1
CORO7 coronin 7
CTSZ cathepsin Z
DBF4B DBF4 zinc finger B
DCN decorin
DEF6 differentially expressed in FDCP 6 homolog (mouse)
EDA ectodysplasin A
EGFL7 EGF-like-domain, multiple 7
EPHB2 EPH receptor B2
EPN1 epsin 1
ERC2-IT1 ERC2 intronic transcript 1
ETV4 ets variant 4
FAM76A family with sequence similarity 76, member A
FBXL7 F-box and leucine-rich repeat protein 7
FLT4 fms-related tyrosine kinase 4
FRMD1 FERM domain containing 1
FSCN1 fascin actin-bundling protein 1
FST follistatin
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GRB10 growth factor receptor-bound protein 10
GYPB glycophorin B (MNS blood group)
HAP1 huntingtin-associated protein 1
HOXC8 homeobox C8
HPS1 Hermansky-Pudlak syndrome 1
IDI2-AS1 IDI2 antisense RNA 1
IFT27 intraflagellar transport 27
IL17RC interleukin 17 receptor C
IL5RA interleukin 5 receptor, alpha
IRF2BP1 interferon regulatory factor 2 binding protein 1
KANSL3 KAT8 regulatory NSL complex subunit 3
LRP2 low density lipoprotein receptor-related protein 2
LRRC15 leucine rich repeat containing 15
LRRC6 leucine rich repeat containing 6
LTBP2 latent transforming growth factor beta binding protein 2
MAPK13 mitogen-activated protein kinase 13
MARCKS myristoylated alanine-rich protein kinase C substrate
MLANA melan-A
MTRF1L mitochondrial translational release factor 1-like
MUC3B mucin 3B, cell surface associated
MXD4 MAX dimerization protein 4
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NME5 NME/NM23 family member 5
NPFFR1 neuropeptide FF receptor 1
NR4A1 nuclear receptor subfamily 4, group A, member 1
NRSN2 neurensin 2
NUMA1 nuclear mitotic apparatus protein 1
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
PCDH11Y protocadherin 11 Y-linked
PCDHA5 protocadherin alpha 5
PCDHB3 protocadherin beta 3
PDCD6 programmed cell death 6
PER1 period circadian clock 1
PLAC1 placenta-specific 1
PLK4 polo-like kinase 4
PORCN porcupine homolog (Drosophila)
PRRC2A proline-rich coiled-coil 2A
RAD54L2 RAD54-like 2 (S. cerevisiae)
RCN1 reticulocalbin 1, EF-hand calcium binding domain
RHEB Ras homolog enriched in brain
RPL10L ribosomal protein L10-like
RPS3A ribosomal protein S3A
RYR2 ryanodine receptor 2 (cardiac)
S100A6 S100 calcium binding protein A6
SETD1A SET domain containing 1A
SFTPB surfactant protein B
SIGLEC8 sialic acid binding Ig-like lectin 8
SKI SKI proto-oncogene
SLC22A14 solute carrier family 22, member 14
SLC22A17 solute carrier family 22, member 17
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
SNCG synuclein, gamma (breast cancer-specific protein 1)
SPEG SPEG complex locus
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
STK17B serine/threonine kinase 17b
STX7 syntaxin 7
STYK1 serine/threonine/tyrosine kinase 1
SYCP2 synaptonemal complex protein 2
TBX19 T-box 19
TNFRSF10C tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
TRIM21 tripartite motif containing 21
UBTD1 ubiquitin domain containing 1
UCN urocortin
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
VLDLR very low density lipoprotein receptor
VN1R1 vomeronasal 1 receptor 1
WNT16 wingless-type MMTV integration site family, member 16
ZNF747 zinc finger protein 747

decreased expression

Symbol Name
ADAP2 ArfGAP with dual PH domains 2
ADM adrenomedullin
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ARHGAP12 Rho GTPase activating protein 12
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
BCL2L2 BCL2-like 2
C11ORF80 chromosome 11 open reading frame 80
CDKN2AIP CDKN2A interacting protein
CEP192 centrosomal protein 192kDa
CEPT1 choline/ethanolamine phosphotransferase 1
CHKB choline kinase beta
CHRM3 cholinergic receptor, muscarinic 3
CNN2 calponin 2
COPG1 coatomer protein complex, subunit gamma 1
CST6 cystatin E/M
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DEAF1 DEAF1 transcription factor
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
EFCAB2 EF-hand calcium binding domain 2
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
EPPK1 epiplakin 1
ERCC4 excision repair cross-complementation group 4
ETAA1 Ewing tumor-associated antigen 1
EXD3 exonuclease 3'-5' domain containing 3
EXTL2 exostosin-like glycosyltransferase 2
FAM188A family with sequence similarity 188, member A
FLRT3 fibronectin leucine rich transmembrane protein 3
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C
GCC1 GRIP and coiled-coil domain containing 1
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GINS4 GINS complex subunit 4 (Sld5 homolog)
GPRASP1 G protein-coupled receptor associated sorting protein 1
GTF2H2B general transcription factor IIH, polypeptide 2B (pseudogene)
HIRA histone cell cycle regulator
HIST1H2AJ histone cluster 1, H2aj
HIST2H2AA3 histone cluster 2, H2aa3
HNRNPUL2 heterogeneous nuclear ribonucleoprotein U-like 2
IL17RA interleukin 17 receptor A
IL4R interleukin 4 receptor
IRAK4 interleukin-1 receptor-associated kinase 4
IRF6 interferon regulatory factor 6
KLHL26 kelch-like family member 26
LOC100287590 uncharacterized LOC100287590
LPXN leupaxin
MAPKBP1 mitogen-activated protein kinase binding protein 1
MBOAT2 membrane bound O-acyltransferase domain containing 2
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MPP5 membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
MSL1 male-specific lethal 1 homolog (Drosophila)
NAV2 neuron navigator 2
NDE1 nudE neurodevelopment protein 1
NELFE negative elongation factor complex member E
NPY1R neuropeptide Y receptor Y1
NR1D2 nuclear receptor subfamily 1, group D, member 2
NUTF2 nuclear transport factor 2
OSBPL11 oxysterol binding protein-like 11
OVOL1 ovo-like zinc finger 1
PRR4 proline rich 4 (lacrimal)
RCOR3 REST corepressor 3
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RNF122 ring finger protein 122
RNF170 ring finger protein 170
RNF2 ring finger protein 2
RPL23AP32 ribosomal protein L23a pseudogene 32
RWDD3 RWD domain containing 3
SCAI suppressor of cancer cell invasion
SCN1B sodium channel, voltage gated, type I beta subunit
SECTM1 secreted and transmembrane 1
SGK1 serum/glucocorticoid regulated kinase 1
SH3BGR SH3 domain binding glutamate-rich protein
SIGLEC15 sialic acid binding Ig-like lectin 15
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SPIDR scaffolding protein involved in DNA repair
SRPX sushi-repeat containing protein, X-linked
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
THNSL1 threonine synthase-like 1 (S. cerevisiae)
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMEM180 transmembrane protein 180
TRIM5 tripartite motif containing 5
WDR62 WD repeat domain 62
WDR76 WD repeat domain 76
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
YARS2 tyrosyl-tRNA synthetase 2, mitochondrial
ZBTB3 zinc finger and BTB domain containing 3
ZNF16 zinc finger protein 16
ZNF324 zinc finger protein 324
ZNF652 zinc finger protein 652
ZNF669 zinc finger protein 669
ZNF816 zinc finger protein 816
ZNRD1-AS1 ZNRD1 antisense RNA 1
ZSCAN9 zinc finger and SCAN domain containing 9