buflomedil-4258 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the buflomedil-4258 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACOT11 acyl-CoA thioesterase 11
AGXT alanine-glyoxylate aminotransferase
ALOX5 arachidonate 5-lipoxygenase
ARHGAP33 Rho GTPase activating protein 33
ARSE arylsulfatase E (chondrodysplasia punctata 1)
B3GALT2 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
BMX BMX non-receptor tyrosine kinase
C8ORF4 chromosome 8 open reading frame 4
CAPN9 calpain 9
CD163 CD163 molecule
CD200 CD200 molecule
CD28 CD28 molecule
CD79A CD79a molecule, immunoglobulin-associated alpha
CDKL1 cyclin-dependent kinase-like 1 (CDC2-related kinase)
CLEC10A C-type lectin domain family 10, member A
CLTA clathrin, light chain A
COL3A1 collagen, type III, alpha 1
CSN3 casein kappa
CYP2U1 cytochrome P450, family 2, subfamily U, polypeptide 1
CYP3A43 cytochrome P450, family 3, subfamily A, polypeptide 43
DDO D-aspartate oxidase
DLGAP1 discs, large (Drosophila) homolog-associated protein 1
DSC1 desmocollin 1
DUSP7 dual specificity phosphatase 7
EBF2 early B-cell factor 2
FAM66D family with sequence similarity 66, member D
FCAR Fc fragment of IgA receptor
FETUB fetuin B
FGB fibrinogen beta chain
FOXE1 forkhead box E1
GNGT1 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
GPR35 G protein-coupled receptor 35
GPR37L1 G protein-coupled receptor 37 like 1
GRIA1 glutamate receptor, ionotropic, AMPA 1
GRM1 glutamate receptor, metabotropic 1
GULP1 GULP, engulfment adaptor PTB domain containing 1
HGD homogentisate 1,2-dioxygenase
HIST1H3I histone cluster 1, H3i
HRG histidine-rich glycoprotein
HTR5A 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled
IGL immunoglobulin lambda locus
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
KCNE1 potassium channel, voltage gated subfamily E regulatory beta subunit 1
KCNH1 potassium channel, voltage gated eag related subfamily H, member 1
KIAA0125 KIAA0125
KIF25 kinesin family member 25
KLK7 kallikrein-related peptidase 7
KRTAP1-3 keratin associated protein 1-3
KRTAP5-9 keratin associated protein 5-9
LMOD1 leiomodin 1 (smooth muscle)
LY9 lymphocyte antigen 9
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MAGIX MAGI family member, X-linked
MNMIP1 manchette microtubule inner protein 1
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MUC4 mucin 4, cell surface associated
MYCNOS MYCN opposite strand
MYOZ2 myozenin 2
NEK9 NIMA-related kinase 9
NOL4 nucleolar protein 4
NRXN3 neurexin 3
NTRK3 neurotrophic tyrosine kinase, receptor, type 3
NUMA1 nuclear mitotic apparatus protein 1
OR1A2 olfactory receptor, family 1, subfamily A, member 2
ORM1 orosomucoid 1
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
PACRG PARK2 co-regulated
PCDHB17P protocadherin beta 17 pseudogene
PCSK6 proprotein convertase subtilisin/kexin type 6
PIK3C2G phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma
PLEK pleckstrin
PLVAP plasmalemma vesicle associated protein
POU1F1 POU class 1 homeobox 1
PROC protein C (inactivator of coagulation factors Va and VIIIa)
PRRX2 paired related homeobox 2
PSG11 pregnancy specific beta-1-glycoprotein 11
PTCH2 patched 2
RCE1 Ras converting CAAX endopeptidase 1
SCN2B sodium channel, voltage gated, type II beta subunit
SFRP5 secreted frizzled-related protein 5
SH3GL3 SH3-domain GRB2-like 3
SLC16A4 solute carrier family 16, member 4
SLC26A10 solute carrier family 26, member 10
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SPINK5 serine peptidase inhibitor, Kazal type 5
SV2B synaptic vesicle glycoprotein 2B
SYCE1L synaptonemal complex central element protein 1-like
TAT tyrosine aminotransferase
TBX21 T-box 21
TBX6 T-box 6
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TTC9 tetratricopeptide repeat domain 9
ZBTB7A zinc finger and BTB domain containing 7A
ZNF208 zinc finger protein 208
ZNF219 zinc finger protein 219

decreased expression

Symbol Name
ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8
ACTG2 actin, gamma 2, smooth muscle, enteric
ADGRG2 adhesion G protein-coupled receptor G2
ADTRP androgen-dependent TFPI-regulating protein
AOC2 amine oxidase, copper containing 2 (retina-specific)
ARHGAP24 Rho GTPase activating protein 24
ARID3A AT rich interactive domain 3A (BRIGHT-like)
ARL14 ADP-ribosylation factor-like 14
ARSJ arylsulfatase family, member J
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2
BGLAP bone gamma-carboxyglutamate (gla) protein
BNC1 basonuclin 1
C11ORF63 chromosome 11 open reading frame 63
C22ORF29 chromosome 22 open reading frame 29
CCNJL cyclin J-like
CCS copper chaperone for superoxide dismutase
CEP112 centrosomal protein 112kDa
CEP131 centrosomal protein 131kDa
CFAP45 cilia and flagella associated protein 45
CFAP69 cilia and flagella associated protein 69
CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7
CHEK2 checkpoint kinase 2
CLDN11 claudin 11
CNIH3 cornichon family AMPA receptor auxiliary protein 3
CSRNP3 cysteine-serine-rich nuclear protein 3
CTC1 CTS telomere maintenance complex component 1
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1
ENOX1 ecto-NOX disulfide-thiol exchanger 1
ERO1LB ERO1-like beta (S. cerevisiae)
EYA4 EYA transcriptional coactivator and phosphatase 4
FAM69A family with sequence similarity 69, member A
FANCC Fanconi anemia, complementation group C
FZD3 frizzled class receptor 3
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GID4 GID complex subunit 4
GLDC glycine dehydrogenase (decarboxylating)
GLI3 GLI family zinc finger 3
GPATCH2L G patch domain containing 2-like
GRAMD1C GRAM domain containing 1C
GSAP gamma-secretase activating protein
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HIRA histone cell cycle regulator
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HOXA1 homeobox A1
ICK intestinal cell (MAK-like) kinase
IFI6 interferon, alpha-inducible protein 6
IRF6 interferon regulatory factor 6
ITPKB inositol-trisphosphate 3-kinase B
KIAA0753 KIAA0753
KIAA1462 KIAA1462
KLHL3 kelch-like family member 3
KRT34 keratin 34, type I
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LRRC61 leucine rich repeat containing 61
LTC4S leukotriene C4 synthase
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MX1 MX dynamin-like GTPase 1
MYO15A myosin XVA
NDP Norrie disease (pseudoglioma)
NR1H3 nuclear receptor subfamily 1, group H, member 3
OSR2 odd-skipped related transciption factor 2
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PAK6 p21 protein (Cdc42/Rac)-activated kinase 6
PALMD palmdelphin
PDE8B phosphodiesterase 8B
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PLAC8 placenta-specific 8
PLCD1 phospholipase C, delta 1
POLL polymerase (DNA directed), lambda
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRPH peripherin
PRR4 proline rich 4 (lacrimal)
PRSS8 protease, serine, 8
RGS17 regulator of G-protein signaling 17
RPL23AP32 ribosomal protein L23a pseudogene 32
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SEC14L2 SEC14-like 2 (S. cerevisiae)
SIX1 SIX homeobox 1
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
TBC1D22B TBC1 domain family, member 22B
TBKBP1 TBK1 binding protein 1
TESK2 testis-specific kinase 2
TEX15 testis expressed 15
TEX40 testis expressed 40
TMEM53 transmembrane protein 53
TXLNG taxilin gamma
WDR91 WD repeat domain 91
ZFP30 ZFP30 zinc finger protein
ZNF140 zinc finger protein 140
ZNF34 zinc finger protein 34
ZNF41 zinc finger protein 41
ZNF492 zinc finger protein 492
ZNF74 zinc finger protein 74