bullous pemphigoid Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
Description An autoimmune disease of skin and connective tissue characterized by large blisters. (Human Disease Ontology, DOID_8506)
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Genes

128 genes co-occuring with the disease bullous pemphigoid in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
COL17A1 collagen, type XVII, alpha 1 3.73992
COL7A1 collagen, type VII, alpha 1 2.32568
DSG3 desmoglein 3 2.22926
DST dystonin 2.14993
CD79A CD79a molecule, immunoglobulin-associated alpha 2.13365
DSG1 desmoglein 1 2.04056
DSP desmoplakin 2.04011
PPL periplakin 1.95817
EVPL envoplakin 1.53745
ITGA6 integrin, alpha 6 1.53304
MACF1 microtubule-actin crosslinking factor 1 1.32498
SRRM1 serine/arginine repetitive matrix 1 1.20353
FN1 fibronectin 1 1.19791
A2ML1 alpha-2-macroglobulin-like 1 1.17206
ITGB4 integrin, beta 4 1.06564
TMIGD2 transmembrane and immunoglobulin domain containing 2 0.99697
LAMA3 laminin, alpha 3 0.930828
LAMB2 laminin, beta 2 (laminin S) 0.90732
LAMC2 laminin, gamma 2 0.903621
IVL involucrin 0.867959
LAMB3 laminin, beta 3 0.861409
FLG filaggrin 0.848307
PLG plasminogen 0.778204
NID1 nidogen 1 0.759008
SYNE3 spectrin repeat containing, nuclear envelope family member 3 0.725311
NCKIPSD NCK interacting protein with SH3 domain 0.703536
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 0.683093
CCL26 chemokine (C-C motif) ligand 26 0.675112
HOXC8 homeobox C8 0.66914
CD4 CD4 molecule 0.661197
LAMC1 laminin, gamma 1 (formerly LAMB2) 0.659215
IL5 interleukin 5 0.653671
LAMB4 laminin, beta 4 0.645375
C3 complement component 3 0.644981
BHLHE23 basic helix-loop-helix family, member e23 0.629635
CD44 CD44 molecule (Indian blood group) 0.629635
DSC1 desmocollin 1 0.624535
RNASE3 ribonuclease, RNase A family, 3 0.617094
PITPNB phosphatidylinositol transfer protein, beta 0.609666
CFP complement factor properdin 0.60342
LPP LIM domain containing preferred translocation partner in lipoma 0.585108
MED10 mediator complex subunit 10 0.579661
DSC3 desmocollin 3 0.57305
ELANE elastase, neutrophil expressed 0.565277
KRT14 keratin 14, type I 0.5645
MMP9 matrix metallopeptidase 9 0.548971
DHODH dihydroorotate dehydrogenase (quinone) 0.543155
C5AR1 complement component 5a receptor 1 0.524974
CD200 CD200 molecule 0.524202
RAB12 RAB12, member RAS oncogene family 0.509192
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 0.498085
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen) 0.496557
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b 0.483224
SEC23A Sec23 homolog A (S. cerevisiae) 0.476014
KIF27 kinesin family member 27 0.464283
DSC2 desmocollin 2 0.463149
CDSN corneodesmosin 0.462394
HSPG2 heparan sulfate proteoglycan 2 0.460129
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23) 0.457864
F8 coagulation factor VIII, procoagulant component 0.452962
KRT13 keratin 13, type I 0.446558
GSTA3 glutathione S-transferase alpha 3 0.440914
GSTA2 glutathione S-transferase alpha 2 0.43941
GSTA4 glutathione S-transferase alpha 4 0.438282
GSTA1 glutathione S-transferase alpha 1 0.432646
FCGRT Fc fragment of IgG, receptor, transporter, alpha 0.425514
KITLG KIT ligand 0.409787
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) 0.393374
PKP3 plakophilin 3 0.389653
PRLH prolactin releasing hormone 0.389281
CCL17 chemokine (C-C motif) ligand 17 0.388538
IL2RA interleukin 2 receptor, alpha 0.37555
CMA1 chymase 1, mast cell 0.365193
ICAM1 intercellular adhesion molecule 1 0.361133
NISCH nischarin 0.35892
HLA-C major histocompatibility complex, class I, C 0.353395
F3 coagulation factor III (thromboplastin, tissue factor) 0.35082
GOSR2 golgi SNAP receptor complex member 2 0.350084
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 0.348614
AHNAK AHNAK nucleoprotein 0.347144
IL1A interleukin 1, alpha 0.346042
CD40 CD40 molecule, TNF receptor superfamily member 5 0.340173
CCL13 chemokine (C-C motif) ligand 13 0.337975
COL4A3BP collagen, type IV, alpha 3 (Goodpasture antigen) binding protein 0.337242
TPMT thiopurine S-methyltransferase 0.334315
PLAU plasminogen activator, urokinase 0.324823
FRK fyn-related Src family tyrosine kinase 0.316819
SEBOX SEBOX homeobox 0.310652
IGKV1D-42 immunoglobulin kappa variable 1D-42 (non-functional) 0.308842
VCL vinculin 0.305948
WARS tryptophanyl-tRNA synthetase 0.305948
SELE selectin E 0.304503
TGFB1 transforming growth factor, beta 1 0.300173
CXCL8 chemokine (C-X-C motif) ligand 8 0.296571
HDAC4 histone deacetylase 4 0.285802
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) 0.27687
CD40LG CD40 ligand 0.27687
NID2 nidogen 2 (osteonidogen) 0.276514
CTBS chitobiase, di-N-acetyl- 0.267622
GPR135 G protein-coupled receptor 135 0.265494
LIM2 lens intrinsic membrane protein 2, 19kDa 0.264077
TGM3 transglutaminase 3 0.25983
HLA-DQB3 major histocompatibility complex, class II, DQ beta 3 0.258064
JUP junction plakoglobin 0.24996
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) 0.238403
CFH complement factor H 0.235268
IL13 interleukin 13 0.217352
IL10 interleukin 10 0.214975
TSPO translocator protein (18kDa) 0.204593
FOXP3 forkhead box P3 0.203933
CMKLR1 chemerin chemokine-like receptor 1 0.192344
IL1B interleukin 1, beta 0.189859
TIMP2 TIMP metallopeptidase inhibitor 2 0.184128
PEG3 paternally expressed 3 0.17952
IL2 interleukin 2 0.178403
PCDH8 protocadherin 8 0.175411
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) 0.175411
COL4A2 collagen, type IV, alpha 2 0.174617
PSAT1 phosphoserine aminotransferase 1 0.170789
MMP10 matrix metallopeptidase 10 0.170544
F2 coagulation factor II (thrombin) 0.168381
TIMP1 TIMP metallopeptidase inhibitor 1 0.167682
IGH immunoglobulin heavy locus 0.164571
CD22 CD22 molecule 0.164571
CKAP5 cytoskeleton associated protein 5 0.164149
CD1B CD1b molecule 0.162908
ZNF436 zinc finger protein 436 0.159302
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 0.157765