| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the bumetanide-2409 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AGFG2 | ArfGAP with FG repeats 2 |
| ALOX5 | arachidonate 5-lipoxygenase |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) |
| APP | amyloid beta (A4) precursor protein |
| AQP9 | aquaporin 9 |
| ARL3 | ADP-ribosylation factor-like 3 |
| ASAP3 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 |
| ASGR2 | asialoglycoprotein receptor 2 |
| ATXN2L | ataxin 2-like |
| B4GALT4 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4 |
| BBS9 | Bardet-Biedl syndrome 9 |
| BCL2 | B-cell CLL/lymphoma 2 |
| BMP1 | bone morphogenetic protein 1 |
| BTD | biotinidase |
| BTN3A1 | butyrophilin, subfamily 3, member A1 |
| C11ORF16 | chromosome 11 open reading frame 16 |
| CCR5 | chemokine (C-C motif) receptor 5 (gene/pseudogene) |
| CD300C | CD300c molecule |
| CDKL1 | cyclin-dependent kinase-like 1 (CDC2-related kinase) |
| CPA2 | carboxypeptidase A2 (pancreatic) |
| CREM | cAMP responsive element modulator |
| CRKL | v-crk avian sarcoma virus CT10 oncogene homolog-like |
| CUL4B | cullin 4B |
| DESI2 | desumoylating isopeptidase 2 |
| DGCR5 | DiGeorge syndrome critical region gene 5 (non-protein coding) |
| DGKG | diacylglycerol kinase, gamma 90kDa |
| DOCK10 | dedicator of cytokinesis 10 |
| DSCAM | Down syndrome cell adhesion molecule |
| FBXO40 | F-box protein 40 |
| FCGR2C | Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene) |
| FGF16 | fibroblast growth factor 16 |
| FGF21 | fibroblast growth factor 21 |
| FOXG1 | forkhead box G1 |
| FOXO4 | forkhead box O4 |
| GJA8 | gap junction protein, alpha 8, 50kDa |
| GPR3 | G protein-coupled receptor 3 |
| GRIK2 | glutamate receptor, ionotropic, kainate 2 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 |
| HCRTR2 | hypocretin (orexin) receptor 2 |
| HOMER3 | homer scaffolding protein 3 |
| IFT27 | intraflagellar transport 27 |
| IGFBP3 | insulin-like growth factor binding protein 3 |
| IHH | indian hedgehog |
| INO80B | INO80 complex subunit B |
| INPP5K | inositol polyphosphate-5-phosphatase K |
| IQCC | IQ motif containing C |
| KCNMB3 | potassium channel subfamily M regulatory beta subunit 3 |
| KCTD17 | potassium channel tetramerization domain containing 17 |
| KIAA0754 | KIAA0754 |
| KIF17 | kinesin family member 17 |
| KLF3 | Kruppel-like factor 3 (basic) |
| KMT2A | lysine (K)-specific methyltransferase 2A |
| KRT81 | keratin 81, type II |
| LRRC37BP1 | leucine rich repeat containing 37B pseudogene 1 |
| MTAP | methylthioadenosine phosphorylase |
| MTSS1L | metastasis suppressor 1-like |
| MYL10 | myosin, light chain 10, regulatory |
| NINJ2 | ninjurin 2 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 |
| PAX8 | paired box 8 |
| PDLIM3 | PDZ and LIM domain 3 |
| PDLIM5 | PDZ and LIM domain 5 |
| PGAP3 | post-GPI attachment to proteins 3 |
| PIN4 | peptidylprolyl cis/trans isomerase, NIMA-interacting 4 |
| PINK1 | PTEN induced putative kinase 1 |
| POLDIP3 | polymerase (DNA-directed), delta interacting protein 3 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PPP1R7 | protein phosphatase 1, regulatory subunit 7 |
| PRX | periaxin |
| PSMB1 | proteasome (prosome, macropain) subunit, beta type, 1 |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 |
| RBPMS | RNA binding protein with multiple splicing |
| ROBO4 | roundabout, axon guidance receptor, homolog 4 (Drosophila) |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 |
| RRBP1 | ribosome binding protein 1 |
| RRN3P1 | RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1 |
| SAPCD1 | suppressor APC domain containing 1 |
| SIGLEC5 | sialic acid binding Ig-like lectin 5 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 |
| SKP2 | S-phase kinase-associated protein 2, E3 ubiquitin protein ligase |
| SLC10A1 | solute carrier family 10 (sodium/bile acid cotransporter), member 1 |
| SLC15A3 | solute carrier family 15 (oligopeptide transporter), member 3 |
| SNAPC5 | small nuclear RNA activating complex, polypeptide 5, 19kDa |
| SPAG8 | sperm associated antigen 8 |
| SS18 | synovial sarcoma translocation, chromosome 18 |
| STAT2 | signal transducer and activator of transcription 2, 113kDa |
| SYK | spleen tyrosine kinase |
| TGFB1 | transforming growth factor, beta 1 |
| TGFBR3 | transforming growth factor, beta receptor III |
| TMOD1 | tropomodulin 1 |
| TNK1 | tyrosine kinase, non-receptor, 1 |
| TNS1 | tensin 1 |
| TUBB1 | tubulin, beta 1 class VI |
| VGF | VGF nerve growth factor inducible |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 |
| ZDHHC24 | zinc finger, DHHC-type containing 24 |
| ZER1 | zyg-11 related, cell cycle regulator |
| ZFP36L1 | ZFP36 ring finger protein-like 1 |
| Symbol | Name |
|---|---|
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 |
| ACP6 | acid phosphatase 6, lysophosphatidic |
| AHDC1 | AT hook, DNA binding motif, containing 1 |
| ARAP3 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 |
| ARMC4 | armadillo repeat containing 4 |
| ASB7 | ankyrin repeat and SOCS box containing 7 |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| BAX | BCL2-associated X protein |
| BHLHE41 | basic helix-loop-helix family, member e41 |
| C1ORF95 | chromosome 1 open reading frame 95 |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 |
| CA11 | carbonic anhydrase XI |
| CAMKMT | calmodulin-lysine N-methyltransferase |
| CAPN15 | calpain 15 |
| CAPN5 | calpain 5 |
| CCDC71 | coiled-coil domain containing 71 |
| CCDC85C | coiled-coil domain containing 85C |
| CDH10 | cadherin 10, type 2 (T2-cadherin) |
| CDK20 | cyclin-dependent kinase 20 |
| CIDEC | cell death-inducing DFFA-like effector c |
| CKB | creatine kinase, brain |
| COLEC10 | collectin sub-family member 10 (C-type lectin) |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DNAL4 | dynein, axonemal, light chain 4 |
| DYM | dymeclin |
| EMILIN2 | elastin microfibril interfacer 2 |
| F5 | coagulation factor V (proaccelerin, labile factor) |
| FBXO46 | F-box protein 46 |
| FGGY | FGGY carbohydrate kinase domain containing |
| FGL1 | fibrinogen-like 1 |
| GDI1 | GDP dissociation inhibitor 1 |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| GNL1 | guanine nucleotide binding protein-like 1 |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| GRIP2 | glutamate receptor interacting protein 2 |
| GSTZ1 | glutathione S-transferase zeta 1 |
| HDHD3 | haloacid dehalogenase-like hydrolase domain containing 3 |
| HIRA | histone cell cycle regulator |
| HIST1H1C | histone cluster 1, H1c |
| HIST1H2AC | histone cluster 1, H2ac |
| IMPDH1 | IMP (inosine 5'-monophosphate) dehydrogenase 1 |
| KIAA1024 | KIAA1024 |
| KIFC1 | kinesin family member C1 |
| KLF1 | Kruppel-like factor 1 (erythroid) |
| KLK15 | kallikrein-related peptidase 15 |
| KLK5 | kallikrein-related peptidase 5 |
| KPTN | kaptin (actin binding protein) |
| LAIR2 | leukocyte-associated immunoglobulin-like receptor 2 |
| LIN7B | lin-7 homolog B (C. elegans) |
| LRRK1 | leucine-rich repeat kinase 1 |
| LTBP2 | latent transforming growth factor beta binding protein 2 |
| MBNL3 | muscleblind-like splicing regulator 3 |
| MICA | MHC class I polypeptide-related sequence A |
| MILR1 | mast cell immunoglobulin-like receptor 1 |
| MLPH | melanophilin |
| MTHFSD | methenyltetrahydrofolate synthetase domain containing |
| MYO5C | myosin VC |
| NPDC1 | neural proliferation, differentiation and control, 1 |
| PCDH12 | protocadherin 12 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 |
| PIK3R5 | phosphoinositide-3-kinase, regulatory subunit 5 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| POMZP3 | POM121 and ZP3 fusion |
| PQLC2 | PQ loop repeat containing 2 |
| PREX2 | phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 |
| PRKAB2 | protein kinase, AMP-activated, beta 2 non-catalytic subunit |
| RAB3A | RAB3A, member RAS oncogene family |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
| RFXAP | regulatory factor X-associated protein |
| RNF122 | ring finger protein 122 |
| S100A12 | S100 calcium binding protein A12 |
| SGMS1 | sphingomyelin synthase 1 |
| SIL1 | SIL1 nucleotide exchange factor |
| SMA4 | glucuronidase, beta pseudogene |
| SPINT1 | serine peptidase inhibitor, Kunitz type 1 |
| SSTR5 | somatostatin receptor 5 |
| STAG3 | stromal antigen 3 |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 |
| SYNJ2BP | synaptojanin 2 binding protein |
| TEC | tec protein tyrosine kinase |
| TMC7 | transmembrane channel-like 7 |
| TMEM209 | transmembrane protein 209 |
| TMEM242 | transmembrane protein 242 |
| TRAIP | TRAF interacting protein |
| TUBA4B | tubulin, alpha 4b |
| UCN | urocortin |
| USP27X | ubiquitin specific peptidase 27, X-linked |
| VANGL1 | VANGL planar cell polarity protein 1 |
| VEGFB | vascular endothelial growth factor B |
| WASF3 | WAS protein family, member 3 |
| ZNF354A | zinc finger protein 354A |
| ZNF493 | zinc finger protein 493 |
| ZNF862 | zinc finger protein 862 |
