| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the bumetanide-5117 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
| ADCY9 | adenylate cyclase 9 |
| ADRBK2 | adrenergic, beta, receptor kinase 2 |
| AFF4 | AF4/FMR2 family, member 4 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 |
| APOE | apolipoprotein E |
| ARHGDIA | Rho GDP dissociation inhibitor (GDI) alpha |
| ARL1 | ADP-ribosylation factor-like 1 |
| C17ORF53 | chromosome 17 open reading frame 53 |
| CA5B | carbonic anhydrase VB, mitochondrial |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) |
| CCDC186 | coiled-coil domain containing 186 |
| CHM | choroideremia (Rab escort protein 1) |
| COL8A1 | collagen, type VIII, alpha 1 |
| COQ7 | coenzyme Q7 homolog, ubiquinone (yeast) |
| CORO1A | coronin, actin binding protein, 1A |
| CREBZF | CREB/ATF bZIP transcription factor |
| CYP2J2 | cytochrome P450, family 2, subfamily J, polypeptide 2 |
| DLK2 | delta-like 2 homolog (Drosophila) |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
| DZIP1 | DAZ interacting zinc finger protein 1 |
| EFHC2 | EF-hand domain (C-terminal) containing 2 |
| EPHA7 | EPH receptor A7 |
| FGB | fibrinogen beta chain |
| FN1 | fibronectin 1 |
| GAD2 | glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 |
| GRIP2 | glutamate receptor interacting protein 2 |
| GSK3A | glycogen synthase kinase 3 alpha |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 |
| HIST1H1D | histone cluster 1, H1d |
| IFI6 | interferon, alpha-inducible protein 6 |
| IL12B | interleukin 12B |
| IL32 | interleukin 32 |
| IL6 | interleukin 6 |
| INPP4A | inositol polyphosphate-4-phosphatase, type I, 107kDa |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KHDRBS2 | KH domain containing, RNA binding, signal transduction associated 2 |
| KITLG | KIT ligand |
| LAT2 | linker for activation of T cells family, member 2 |
| LIPG | lipase, endothelial |
| LMAN1 | lectin, mannose-binding, 1 |
| LMNB1 | lamin B1 |
| MAPK8IP3 | mitogen-activated protein kinase 8 interacting protein 3 |
| MCL1 | myeloid cell leukemia 1 |
| MDM4 | MDM4, p53 regulator |
| MET | MET proto-oncogene, receptor tyrosine kinase |
| MGAT2 | mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase |
| MGAT3 | mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase |
| MVK | mevalonate kinase |
| NAALAD2 | N-acetylated alpha-linked acidic dipeptidase 2 |
| NAB2 | NGFI-A binding protein 2 (EGR1 binding protein 2) |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| PDCD2 | programmed cell death 2 |
| PDGFA | platelet-derived growth factor alpha polypeptide |
| PDLIM4 | PDZ and LIM domain 4 |
| PECAM1 | platelet/endothelial cell adhesion molecule 1 |
| PLK4 | polo-like kinase 4 |
| PPP1R2P9 | protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9 |
| PRB1 | proline-rich protein BstNI subfamily 1 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 |
| PVR | poliovirus receptor |
| RAB11FIP3 | RAB11 family interacting protein 3 (class II) |
| RAB6A | RAB6A, member RAS oncogene family |
| RB1 | retinoblastoma 1 |
| RCAN1 | regulator of calcineurin 1 |
| RDX | radixin |
| RGS6 | regulator of G-protein signaling 6 |
| RNF6 | ring finger protein (C3H2C3 type) 6 |
| RPL10 | ribosomal protein L10 |
| RPS9 | ribosomal protein S9 |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SFTPB | surfactant protein B |
| SKP2 | S-phase kinase-associated protein 2, E3 ubiquitin protein ligase |
| SLAMF7 | SLAM family member 7 |
| SLC25A30 | solute carrier family 25, member 30 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor |
| SORBS1 | sorbin and SH3 domain containing 1 |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| ST7L | suppression of tumorigenicity 7 like |
| STAT1 | signal transducer and activator of transcription 1, 91kDa |
| STK4 | serine/threonine kinase 4 |
| STRN | striatin, calmodulin binding protein |
| SYDE1 | synapse defective 1, Rho GTPase, homolog 1 (C. elegans) |
| TADA2A | transcriptional adaptor 2A |
| TBC1D8B | TBC1 domain family, member 8B (with GRAM domain) |
| TMEFF1 | transmembrane protein with EGF-like and two follistatin-like domains 1 |
| TMEM231 | transmembrane protein 231 |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TUBA4B | tubulin, alpha 4b |
| UBXN1 | UBX domain protein 1 |
| UST | uronyl-2-sulfotransferase |
| VWA5A | von Willebrand factor A domain containing 5A |
| ZNF268 | zinc finger protein 268 |
| ZNF768 | zinc finger protein 768 |
| Symbol | Name |
|---|---|
| ABCA3 | ATP-binding cassette, sub-family A (ABC1), member 3 |
| ABHD8 | abhydrolase domain containing 8 |
| ADCY6 | adenylate cyclase 6 |
| ADGRB2 | adhesion G protein-coupled receptor B2 |
| ANKRD36 | ankyrin repeat domain 36 |
| AP1G2 | adaptor-related protein complex 1, gamma 2 subunit |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| ASH2L | ash2 (absent, small, or homeotic)-like (Drosophila) |
| B4GALT2 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 |
| BAHD1 | bromo adjacent homology domain containing 1 |
| BAK1 | BCL2-antagonist/killer 1 |
| BMS1 | BMS1 ribosome biogenesis factor |
| C6ORF47 | chromosome 6 open reading frame 47 |
| CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 |
| CDH7 | cadherin 7, type 2 |
| CDIP1 | cell death-inducing p53 target 1 |
| CFAP69 | cilia and flagella associated protein 69 |
| CISH | cytokine inducible SH2-containing protein |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
| CTAGE9 | CTAGE family, member 9 |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
| CUL7 | cullin 7 |
| DAP | death-associated protein |
| DENND4B | DENN/MADD domain containing 4B |
| DEPTOR | DEP domain containing MTOR-interacting protein |
| DSPP | dentin sialophosphoprotein |
| DZANK1 | double zinc ribbon and ankyrin repeat domains 1 |
| EPHB6 | EPH receptor B6 |
| EPPK1 | epiplakin 1 |
| EYA4 | EYA transcriptional coactivator and phosphatase 4 |
| FAM186A | family with sequence similarity 186, member A |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FBXO2 | F-box protein 2 |
| GABBR1 | gamma-aminobutyric acid (GABA) B receptor, 1 |
| GMIP | GEM interacting protein |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HAUS2 | HAUS augmin-like complex, subunit 2 |
| HDAC5 | histone deacetylase 5 |
| HIRA | histone cell cycle regulator |
| HIST1H3F | histone cluster 1, H3f |
| HLA-DMA | major histocompatibility complex, class II, DM alpha |
| HOXA2 | homeobox A2 |
| HOXC10 | homeobox C10 |
| IFNAR1 | interferon (alpha, beta and omega) receptor 1 |
| INPP5A | inositol polyphosphate-5-phosphatase, 40kDa |
| ITPKC | inositol-trisphosphate 3-kinase C |
| KCTD7 | potassium channel tetramerization domain containing 7 |
| KIAA0319L | KIAA0319-like |
| KLF13 | Kruppel-like factor 13 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 |
| LOC390998 | ribosomal protein L10 pseudogene |
| LRFN3 | leucine rich repeat and fibronectin type III domain containing 3 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MAP3K6 | mitogen-activated protein kinase kinase kinase 6 |
| MAP6D1 | MAP6 domain containing 1 |
| MATN3 | matrilin 3 |
| MON1B | MON1 secretory trafficking family member B |
| MTHFSD | methenyltetrahydrofolate synthetase domain containing |
| MUC3A | mucin 3A, cell surface associated |
| NBEAL2 | neurobeachin-like 2 |
| NOL10 | nucleolar protein 10 |
| NXPH4 | neurexophilin 4 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PAK3 | p21 protein (Cdc42/Rac)-activated kinase 3 |
| PBX3 | pre-B-cell leukemia homeobox 3 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PMM2 | phosphomannomutase 2 |
| POLL | polymerase (DNA directed), lambda |
| REPS2 | RALBP1 associated Eps domain containing 2 |
| RHOBTB2 | Rho-related BTB domain containing 2 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| SCAI | suppressor of cancer cell invasion |
| SCML1 | sex comb on midleg-like 1 (Drosophila) |
| SCUBE3 | signal peptide, CUB domain, EGF-like 3 |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SHPK | sedoheptulokinase |
| SLC17A2 | solute carrier family 17, member 2 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 |
| SRGAP2 | SLIT-ROBO Rho GTPase activating protein 2 |
| SUN2 | Sad1 and UNC84 domain containing 2 |
| TGFB3 | transforming growth factor, beta 3 |
| THRAP3 | thyroid hormone receptor associated protein 3 |
| TRIM45 | tripartite motif containing 45 |
| TUBA3C | tubulin, alpha 3c |
| USB1 | U6 snRNA biogenesis 1 |
| VAT1 | vesicle amine transport 1 |
| VGF | VGF nerve growth factor inducible |
| VPS11 | vacuolar protein sorting 11 homolog (S. cerevisiae) |
| WDR4 | WD repeat domain 4 |
| WDR76 | WD repeat domain 76 |
| YPEL1 | yippee-like 1 (Drosophila) |
| ZBTB39 | zinc finger and BTB domain containing 39 |
| ZC3H3 | zinc finger CCCH-type containing 3 |
| ZFP30 | ZFP30 zinc finger protein |
| ZNF446 | zinc finger protein 446 |
| ZNF606 | zinc finger protein 606 |
| ZNF76 | zinc finger protein 76 |
