| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the bumetanide-5542 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAGAB | alpha- and gamma-adaptin binding protein |
| ABHD17B | abhydrolase domain containing 17B |
| ADGRE2 | adhesion G protein-coupled receptor E2 |
| AGAP2 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) |
| ALOX15 | arachidonate 15-lipoxygenase |
| ANGEL2 | angel homolog 2 (Drosophila) |
| ATG13 | autophagy related 13 |
| BDNF | brain-derived neurotrophic factor |
| BMP5 | bone morphogenetic protein 5 |
| BMP6 | bone morphogenetic protein 6 |
| C11ORF16 | chromosome 11 open reading frame 16 |
| C2ORF27A | chromosome 2 open reading frame 27A |
| CALD1 | caldesmon 1 |
| CAPN10 | calpain 10 |
| CASP9 | caspase 9, apoptosis-related cysteine peptidase |
| CLDN17 | claudin 17 |
| CNTD2 | cyclin N-terminal domain containing 2 |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| DCN | decorin |
| EDRF1 | erythroid differentiation regulatory factor 1 |
| ELOVL2 | ELOVL fatty acid elongase 2 |
| FASLG | Fas ligand (TNF superfamily, member 6) |
| FUT4 | fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) |
| GABRR2 | gamma-aminobutyric acid (GABA) A receptor, rho 2 |
| GGA3 | golgi-associated, gamma adaptin ear containing, ARF binding protein 3 |
| GNG3 | guanine nucleotide binding protein (G protein), gamma 3 |
| GPC4 | glypican 4 |
| HIST1H1E | histone cluster 1, H1e |
| HOXA4 | homeobox A4 |
| HOXB6 | homeobox B6 |
| HRASLS2 | HRAS-like suppressor 2 |
| HYI | hydroxypyruvate isomerase (putative) |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IFITM1 | interferon induced transmembrane protein 1 |
| IFNA14 | interferon, alpha 14 |
| IL11 | interleukin 11 |
| IL1B | interleukin 1, beta |
| IQCC | IQ motif containing C |
| ISG15 | ISG15 ubiquitin-like modifier |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 |
| KIAA0754 | KIAA0754 |
| LRRC17 | leucine rich repeat containing 17 |
| LY9 | lymphocyte antigen 9 |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 |
| MED25 | mediator complex subunit 25 |
| MTRF1L | mitochondrial translational release factor 1-like |
| MYO15A | myosin XVA |
| NAA11 | N(alpha)-acetyltransferase 11, NatA catalytic subunit |
| NEURL1 | neuralized E3 ubiquitin protein ligase 1 |
| NRIP3 | nuclear receptor interacting protein 3 |
| OSMR | oncostatin M receptor |
| PDLIM5 | PDZ and LIM domain 5 |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| POU4F2 | POU class 4 homeobox 2 |
| PPFIBP2 | PTPRF interacting protein, binding protein 2 (liprin beta 2) |
| PPP2R2B | protein phosphatase 2, regulatory subunit B, beta |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 |
| PRKCH | protein kinase C, eta |
| PSG9 | pregnancy specific beta-1-glycoprotein 9 |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| PTPN18 | protein tyrosine phosphatase, non-receptor type 18 (brain-derived) |
| QPCTL | glutaminyl-peptide cyclotransferase-like |
| RAC2 | ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) |
| RARA | retinoic acid receptor, alpha |
| RBM5 | RNA binding motif protein 5 |
| RNF17 | ring finger protein 17 |
| RPL7 | ribosomal protein L7 |
| SCRN3 | secernin 3 |
| SCUBE3 | signal peptide, CUB domain, EGF-like 3 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) |
| SGCD | sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) |
| SIX1 | SIX homeobox 1 |
| SLC12A4 | solute carrier family 12 (potassium/chloride transporter), member 4 |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SLCO1B1 | solute carrier organic anion transporter family, member 1B1 |
| SOS2 | son of sevenless homolog 2 (Drosophila) |
| SPDEF | SAM pointed domain containing ETS transcription factor |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 |
| SPTBN5 | spectrin, beta, non-erythrocytic 5 |
| STAB2 | stabilin 2 |
| SYDE1 | synapse defective 1, Rho GTPase, homolog 1 (C. elegans) |
| TECPR2 | tectonin beta-propeller repeat containing 2 |
| TICAM1 | toll-like receptor adaptor molecule 1 |
| TMEM63A | transmembrane protein 63A |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b |
| TSSK2 | testis-specific serine kinase 2 |
| TTLL3 | tubulin tyrosine ligase-like family member 3 |
| UTP14A | UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) |
| VAC14 | Vac14 homolog (S. cerevisiae) |
| VIM | vimentin |
| VIPR2 | vasoactive intestinal peptide receptor 2 |
| ZC3H7B | zinc finger CCCH-type containing 7B |
| ZNF324 | zinc finger protein 324 |
| Symbol | Name |
|---|---|
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 |
| ACADSB | acyl-CoA dehydrogenase, short/branched chain |
| ADGRG2 | adhesion G protein-coupled receptor G2 |
| AP4M1 | adaptor-related protein complex 4, mu 1 subunit |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
| ATP13A2 | ATPase type 13A2 |
| BAHD1 | bromo adjacent homology domain containing 1 |
| BCAS1 | breast carcinoma amplified sequence 1 |
| BCORL1 | BCL6 corepressor-like 1 |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| C8ORF60 | chromosome 8 open reading frame 60 |
| C9ORF9 | chromosome 9 open reading frame 9 |
| CAMKMT | calmodulin-lysine N-methyltransferase |
| CCDC69 | coiled-coil domain containing 69 |
| CCT6B | chaperonin containing TCP1, subunit 6B (zeta 2) |
| CD83 | CD83 molecule |
| CDK20 | cyclin-dependent kinase 20 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CFAP44 | cilia and flagella associated protein 44 |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| CLEC4E | C-type lectin domain family 4, member E |
| CTAGE9 | CTAGE family, member 9 |
| CTNNBIP1 | catenin, beta interacting protein 1 |
| DDX43 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 |
| DUSP2 | dual specificity phosphatase 2 |
| ECI2 | enoyl-CoA delta isomerase 2 |
| EFNA3 | ephrin-A3 |
| ELSPBP1 | epididymal sperm binding protein 1 |
| EPPK1 | epiplakin 1 |
| ETNK2 | ethanolamine kinase 2 |
| EXO5 | exonuclease 5 |
| F2R | coagulation factor II (thrombin) receptor |
| FBXL15 | F-box and leucine-rich repeat protein 15 |
| FUZ | fuzzy planar cell polarity protein |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GLI3 | GLI family zinc finger 3 |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| GTPBP2 | GTP binding protein 2 |
| HINFP | histone H4 transcription factor |
| HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 |
| HOOK2 | hook microtubule-tethering protein 2 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 |
| IRF1 | interferon regulatory factor 1 |
| KLHL12 | kelch-like family member 12 |
| KRI1 | KRI1 homolog (S. cerevisiae) |
| LMO2 | LIM domain only 2 (rhombotin-like 1) |
| LOC730101 | uncharacterized LOC730101 |
| LYPD1 | LY6/PLAUR domain containing 1 |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 |
| MBNL3 | muscleblind-like splicing regulator 3 |
| MBTD1 | mbt domain containing 1 |
| MECR | mitochondrial trans-2-enoyl-CoA reductase |
| MNX1 | motor neuron and pancreas homeobox 1 |
| MOGS | mannosyl-oligosaccharide glucosidase |
| NIPAL2 | NIPA-like domain containing 2 |
| PADI1 | peptidyl arginine deiminase, type I |
| PAOX | polyamine oxidase (exo-N4-amino) |
| PDE8B | phosphodiesterase 8B |
| PIK3R5 | phosphoinositide-3-kinase, regulatory subunit 5 |
| POLR2J2 | polymerase (RNA) II (DNA directed) polypeptide J2 |
| POM121 | POM121 transmembrane nucleoporin |
| PPAN | peter pan homolog (Drosophila) |
| PPIP5K1 | diphosphoinositol pentakisphosphate kinase 1 |
| PPM1H | protein phosphatase, Mg2+/Mn2+ dependent, 1H |
| PPT2 | palmitoyl-protein thioesterase 2 |
| PREX2 | phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 |
| PRKACG | protein kinase, cAMP-dependent, catalytic, gamma |
| PRSS22 | protease, serine, 22 |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| RANGRF | RAN guanine nucleotide release factor |
| RNF122 | ring finger protein 122 |
| ROM1 | retinal outer segment membrane protein 1 |
| RPH3AL | rabphilin 3A-like (without C2 domains) |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SLC12A9 | solute carrier family 12, member 9 |
| SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 |
| SLC35C2 | solute carrier family 35 (GDP-fucose transporter), member C2 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) |
| TGFBR3 | transforming growth factor, beta receptor III |
| THBS3 | thrombospondin 3 |
| TMEM45A | transmembrane protein 45A |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 |
| TRAIP | TRAF interacting protein |
| TTC4 | tetratricopeptide repeat domain 4 |
| VWA1 | von Willebrand factor A domain containing 1 |
| WDR62 | WD repeat domain 62 |
| WDR76 | WD repeat domain 76 |
| XYLT2 | xylosyltransferase II |
| ZBED1 | zinc finger, BED-type containing 1 |
| ZNF16 | zinc finger protein 16 |
| ZNF675 | zinc finger protein 675 |
| ZNF696 | zinc finger protein 696 |
| ZNF767P | zinc finger family member 767, pseudogene |
