bunina body Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description Small granular inclusions (about 1-3 microns in diameter) found in the anterior horn cells, and appearing either singly or in a group. Sometimes they are arranged in small beaded chains. Bunina bodies express cystatin C and consist of electron-dense amorphous material that contains tubules or vesicular structures. The amorphous material frequently includes a cytoplasmic island containing neurofilaments and other micro-organelles. (Gene Ontology, GO_0097407)
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Genes

25 proteins co-occuring with the bunina body cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
CST3 cystatin C 1.86211
BBS2 Bardet-Biedl syndrome 2 1.76303
TARDBP TAR DNA binding protein 1.64195
SOD2 superoxide dismutase 2, mitochondrial 1.03479
GLG1 golgi glycoprotein 1 0.889783
FUS FUS RNA binding protein 0.771819
MNDA myeloid cell nuclear differentiation antigen 0.727494
C9ORF72 chromosome 9 open reading frame 72 0.608241
TFG TRK-fused gene 0.528388
SQSTM1 sequestosome 1 0.496205
OPTN optineurin 0.459203
PMP22 peripheral myelin protein 22 0.324576
CTSH cathepsin H 0.3227
HTRA2 HtrA serine peptidase 2 0.319702
MAPT microtubule-associated protein tau 0.311851
UNG uracil-DNA glycosylase 0.289199
CA1 carbonic anhydrase I 0.283295
CHGB chromogranin B 0.275569
CAMP cathelicidin antimicrobial peptide 0.267505
SCG2 secretogranin II 0.252927
TF transferrin 0.249302
SYP synaptophysin 0.241716
CTSB cathepsin B 0.190495
CD68 CD68 molecule 0.189539
MAP2 microtubule-associated protein 2 0.159074