| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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200 genes differentially expressed following the bupivacaine-5112 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAK1 | AP2 associated kinase 1 |
| ADRA2B | adrenoceptor alpha 2B |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 |
| AQP3 | aquaporin 3 (Gill blood group) |
| ARHGAP26 | Rho GTPase activating protein 26 |
| ATP11A | ATPase, class VI, type 11A |
| BCL6 | B-cell CLL/lymphoma 6 |
| C14ORF1 | chromosome 14 open reading frame 1 |
| C1ORF54 | chromosome 1 open reading frame 54 |
| CAPN6 | calpain 6 |
| CCL2 | chemokine (C-C motif) ligand 2 |
| CCT6B | chaperonin containing TCP1, subunit 6B (zeta 2) |
| CD209 | CD209 molecule |
| CD33 | CD33 molecule |
| CEND1 | cell cycle exit and neuronal differentiation 1 |
| CHI3L2 | chitinase 3-like 2 |
| CIB2 | calcium and integrin binding family member 2 |
| CLIC5 | chloride intracellular channel 5 |
| COL11A2 | collagen, type XI, alpha 2 |
| COL8A1 | collagen, type VIII, alpha 1 |
| CREB3L1 | cAMP responsive element binding protein 3-like 1 |
| CSHL1 | chorionic somatomammotropin hormone-like 1 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 |
| DBF4B | DBF4 zinc finger B |
| DDX51 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 51 |
| DIAPH2-AS1 | DIAPH2 antisense RNA 1 |
| DICER1 | dicer 1, ribonuclease type III |
| DOT1L | DOT1-like histone H3K79 methyltransferase |
| DTNA | dystrobrevin, alpha |
| ENO3 | enolase 3 (beta, muscle) |
| ESR1 | estrogen receptor 1 |
| FCAR | Fc fragment of IgA receptor |
| FGFR1 | fibroblast growth factor receptor 1 |
| GLE1 | GLE1 RNA export mediator |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide |
| GP1BA | glycoprotein Ib (platelet), alpha polypeptide |
| GPC3 | glypican 3 |
| HCRP1 | hepatocellular carcinoma-related HCRP1 |
| HFE | hemochromatosis |
| HIST1H2AL | histone cluster 1, H2al |
| ICOSLG | inducible T-cell co-stimulator ligand |
| IGF1R | insulin-like growth factor 1 receptor |
| IGH | immunoglobulin heavy locus |
| IHH | indian hedgehog |
| IL1RN | interleukin 1 receptor antagonist |
| INPP4A | inositol polyphosphate-4-phosphatase, type I, 107kDa |
| IRF4 | interferon regulatory factor 4 |
| KCTD13 | potassium channel tetramerization domain containing 13 |
| KLF3 | Kruppel-like factor 3 (basic) |
| KLHL22 | kelch-like family member 22 |
| LAT2 | linker for activation of T cells family, member 2 |
| LHX3 | LIM homeobox 3 |
| LOC729164 | hCG1732469 |
| LOX | lysyl oxidase |
| LRRC48 | leucine rich repeat containing 48 |
| LY9 | lymphocyte antigen 9 |
| MMRN2 | multimerin 2 |
| MRPL41 | mitochondrial ribosomal protein L41 |
| MST1 | macrophage stimulating 1 |
| MTCP1 | mature T-cell proliferation 1 |
| MVD | mevalonate (diphospho) decarboxylase |
| NAB2 | NGFI-A binding protein 2 (EGR1 binding protein 2) |
| NOS1 | nitric oxide synthase 1 (neuronal) |
| NRCAM | neuronal cell adhesion molecule |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa |
| OSGIN2 | oxidative stress induced growth inhibitor family member 2 |
| PATZ1 | POZ (BTB) and AT hook containing zinc finger 1 |
| PDE8B | phosphodiesterase 8B |
| PDLIM3 | PDZ and LIM domain 3 |
| PDPR | pyruvate dehydrogenase phosphatase regulatory subunit |
| PKLR | pyruvate kinase, liver and RBC |
| PODNL1 | podocan-like 1 |
| PSMB1 | proteasome (prosome, macropain) subunit, beta type, 1 |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) |
| PTPRH | protein tyrosine phosphatase, receptor type, H |
| PVR | poliovirus receptor |
| RAB11FIP3 | RAB11 family interacting protein 3 (class II) |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 |
| RB1 | retinoblastoma 1 |
| RFXAP | regulatory factor X-associated protein |
| RTCA | RNA 3'-terminal phosphate cyclase |
| RUNX1 | runt-related transcription factor 1 |
| SAA4 | serum amyloid A4, constitutive |
| SAMD4A | sterile alpha motif domain containing 4A |
| SERGEF | secretion regulating guanine nucleotide exchange factor |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) |
| SORBS1 | sorbin and SH3 domain containing 1 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 |
| STRN | striatin, calmodulin binding protein |
| STS | steroid sulfatase (microsomal), isozyme S |
| TCF3 | transcription factor 3 |
| TELO2 | telomere maintenance 2 |
| VIPR2 | vasoactive intestinal peptide receptor 2 |
| YIPF4 | Yip1 domain family, member 4 |
| ZER1 | zyg-11 related, cell cycle regulator |
| ZNF528 | zinc finger protein 528 |
| ZNF821 | zinc finger protein 821 |
| ZSCAN2 | zinc finger and SCAN domain containing 2 |
| Symbol | Name |
|---|---|
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 |
| ADGRB2 | adhesion G protein-coupled receptor B2 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) |
| ALDH3B1 | aldehyde dehydrogenase 3 family, member B1 |
| APOLD1 | apolipoprotein L domain containing 1 |
| ATAD5 | ATPase family, AAA domain containing 5 |
| AXIN1 | axin 1 |
| BCAS3 | breast carcinoma amplified sequence 3 |
| BEX1 | brain expressed, X-linked 1 |
| BFSP1 | beaded filament structural protein 1, filensin |
| BSPRY | B-box and SPRY domain containing |
| C1ORF159 | chromosome 1 open reading frame 159 |
| C4ORF19 | chromosome 4 open reading frame 19 |
| CABYR | calcium binding tyrosine-(Y)-phosphorylation regulated |
| CADPS2 | Ca++-dependent secretion activator 2 |
| CARD8 | caspase recruitment domain family, member 8 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CCDC25 | coiled-coil domain containing 25 |
| CCNA1 | cyclin A1 |
| CENPO | centromere protein O |
| CHRNB1 | cholinergic receptor, nicotinic, beta 1 (muscle) |
| CNKSR1 | connector enhancer of kinase suppressor of Ras 1 |
| CNNM1 | cyclin and CBS domain divalent metal cation transport mediator 1 |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
| CRYBB2P1 | crystallin, beta B2 pseudogene 1 |
| CXORF56 | chromosome X open reading frame 56 |
| DYNC1I1 | dynein, cytoplasmic 1, intermediate chain 1 |
| ECM1 | extracellular matrix protein 1 |
| EHF | ets homologous factor |
| ELAVL2 | ELAV like neuron-specific RNA binding protein 2 |
| EVPL | envoplakin |
| EYA4 | EYA transcriptional coactivator and phosphatase 4 |
| FAM186A | family with sequence similarity 186, member A |
| FBXO2 | F-box protein 2 |
| FSD1 | fibronectin type III and SPRY domain containing 1 |
| HIRA | histone cell cycle regulator |
| HIST1H1T | histone cluster 1, H1t |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha |
| HOXA1 | homeobox A1 |
| HOXA4 | homeobox A4 |
| HOXC10 | homeobox C10 |
| IFT54 | intraflagellar transport 54 |
| IL22 | interleukin 22 |
| INPPL1 | inositol polyphosphate phosphatase-like 1 |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| ITGB2 | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) |
| KLF13 | Kruppel-like factor 13 |
| KLHL36 | kelch-like family member 36 |
| LOC390998 | ribosomal protein L10 pseudogene |
| LRFN3 | leucine rich repeat and fibronectin type III domain containing 3 |
| LRRK1 | leucine-rich repeat kinase 1 |
| MAGEF1 | melanoma antigen family F1 |
| MAPK12 | mitogen-activated protein kinase 12 |
| METTL16 | methyltransferase like 16 |
| MTA2 | metastasis associated 1 family, member 2 |
| MTHFSD | methenyltetrahydrofolate synthetase domain containing |
| MUM1 | melanoma associated antigen (mutated) 1 |
| MYH15 | myosin, heavy chain 15 |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NTF3 | neurotrophin 3 |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| OSR2 | odd-skipped related transciption factor 2 |
| POLL | polymerase (DNA directed), lambda |
| PTK6 | protein tyrosine kinase 6 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| SCIN | scinderin |
| SDC3 | syndecan 3 |
| SEC61A2 | Sec61 alpha 2 subunit (S. cerevisiae) |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SIRAL2 | SIR2 antiphage like 2 |
| SLC17A5 | solute carrier family 17 (acidic sugar transporter), member 5 |
| SLN | sarcolipin |
| SMAD7 | SMAD family member 7 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 |
| TBC1D19 | TBC1 domain family, member 19 |
| TM7SF2 | transmembrane 7 superfamily member 2 |
| TNFSF13 | tumor necrosis factor (ligand) superfamily, member 13 |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 |
| TRAPPC13 | trafficking protein particle complex 13 |
| TRIM5 | tripartite motif containing 5 |
| TXK | TXK tyrosine kinase |
| UBXN6 | UBX domain protein 6 |
| USP6 | ubiquitin specific peptidase 6 |
| USP6NL | USP6 N-terminal like |
| VWA1 | von Willebrand factor A domain containing 1 |
| WWC2 | WW and C2 domain containing 2 |
| XAB2 | XPA binding protein 2 |
| YPEL1 | yippee-like 1 (Drosophila) |
| ZFP30 | ZFP30 zinc finger protein |
| ZNF180 | zinc finger protein 180 |
| ZNF225 | zinc finger protein 225 |
| ZNF254 | zinc finger protein 254 |
| ZNF280D | zinc finger protein 280D |
| ZNF324 | zinc finger protein 324 |
| ZNF668 | zinc finger protein 668 |
| ZNF76 | zinc finger protein 76 |
