| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the bupivacaine-5537 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADGRD2 | adhesion G protein-coupled receptor D2 |
| ANKRD2 | ankyrin repeat domain 2 (stretch responsive muscle) |
| ARTN | artemin |
| BAHD1 | bromo adjacent homology domain containing 1 |
| BICC1 | BicC family RNA binding protein 1 |
| BTD | biotinidase |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| C5AR1 | complement component 5a receptor 1 |
| C8A | complement component 8, alpha polypeptide |
| CCNJL | cyclin J-like |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| CNPY4 | canopy FGF signaling regulator 4 |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| DNAH17 | dynein, axonemal, heavy chain 17 |
| DSC2 | desmocollin 2 |
| DSCAM | Down syndrome cell adhesion molecule |
| DST | dystonin |
| ECHDC3 | enoyl CoA hydratase domain containing 3 |
| ELOVL2 | ELOVL fatty acid elongase 2 |
| ERAP1 | endoplasmic reticulum aminopeptidase 1 |
| FAM214B | family with sequence similarity 214, member B |
| FSCN1 | fascin actin-bundling protein 1 |
| GAMT | guanidinoacetate N-methyltransferase |
| GLB1L | galactosidase, beta 1-like |
| GNAO1 | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O |
| GTDC1 | glycosyltransferase-like domain containing 1 |
| HPCAL4 | hippocalcin like 4 |
| IGLV4-60 | immunoglobulin lambda variable 4-60 |
| INE1 | inactivation escape 1 (non-protein coding) |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 |
| KANK1 | KN motif and ankyrin repeat domains 1 |
| KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KIAA0754 | KIAA0754 |
| KIAA0930 | KIAA0930 |
| KRT17 | keratin 17, type I |
| KRT6B | keratin 6B, type II |
| LAIR1 | leukocyte-associated immunoglobulin-like receptor 1 |
| LAMB3 | laminin, beta 3 |
| LEF1 | lymphoid enhancer-binding factor 1 |
| LIG4 | ligase IV, DNA, ATP-dependent |
| MARK2 | MAP/microtubule affinity-regulating kinase 2 |
| MAX | MYC associated factor X |
| NDNF | neuron-derived neurotrophic factor |
| NPPA | natriuretic peptide A |
| NPRL2 | nitrogen permease regulator-like 2 (S. cerevisiae) |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) |
| NRF1 | nuclear respiratory factor 1 |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PAWR | PRKC, apoptosis, WT1, regulator |
| PBX2 | pre-B-cell leukemia homeobox 2 |
| PDE6C | phosphodiesterase 6C, cGMP-specific, cone, alpha prime |
| PI4K2A | phosphatidylinositol 4-kinase type 2 alpha |
| PLA2G4C | phospholipase A2, group IVC (cytosolic, calcium-independent) |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) |
| POLG | polymerase (DNA directed), gamma |
| POU4F2 | POU class 4 homeobox 2 |
| PRB1 | proline-rich protein BstNI subfamily 1 |
| PRKCH | protein kinase C, eta |
| PSG9 | pregnancy specific beta-1-glycoprotein 9 |
| QPCTL | glutaminyl-peptide cyclotransferase-like |
| RAB11B | RAB11B, member RAS oncogene family |
| RABEP1 | rabaptin, RAB GTPase binding effector protein 1 |
| RHBG | Rh family, B glycoprotein (gene/pseudogene) |
| RIMS2 | regulating synaptic membrane exocytosis 2 |
| RNF5 | ring finger protein 5, E3 ubiquitin protein ligase |
| RUFY3 | RUN and FYVE domain containing 3 |
| S100A9 | S100 calcium binding protein A9 |
| SCAPER | S-phase cyclin A-associated protein in the ER |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit |
| SELPLG | selectin P ligand |
| SGSM3 | small G protein signaling modulator 3 |
| SIGLEC6 | sialic acid binding Ig-like lectin 6 |
| SIRT5 | sirtuin 5 |
| SLC13A4 | solute carrier family 13 (sodium/sulfate symporter), member 4 |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SLC43A3 | solute carrier family 43, member 3 |
| SPTLC2 | serine palmitoyltransferase, long chain base subunit 2 |
| SYBU | syntabulin (syntaxin-interacting) |
| SYDE1 | synapse defective 1, Rho GTPase, homolog 1 (C. elegans) |
| TBXA2R | thromboxane A2 receptor |
| TCEB3B | transcription elongation factor B polypeptide 3B (elongin A2) |
| TGM2 | transglutaminase 2 |
| TLE2 | transducin-like enhancer of split 2 |
| TMCC2 | transmembrane and coiled-coil domain family 2 |
| TMEM63A | transmembrane protein 63A |
| TTC38 | tetratricopeptide repeat domain 38 |
| USP22 | ubiquitin specific peptidase 22 |
| UTRN | utrophin |
| VAC14 | Vac14 homolog (S. cerevisiae) |
| VARS | valyl-tRNA synthetase |
| VEGFA | vascular endothelial growth factor A |
| ZC3H7B | zinc finger CCCH-type containing 7B |
| ZMIZ2 | zinc finger, MIZ-type containing 2 |
| ZNF24 | zinc finger protein 24 |
| ZNF821 | zinc finger protein 821 |
| Symbol | Name |
|---|---|
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 |
| ACAD10 | acyl-CoA dehydrogenase family, member 10 |
| ACOT8 | acyl-CoA thioesterase 8 |
| ADGRE5 | adhesion G protein-coupled receptor E5 |
| AIDA | axin interactor, dorsalization associated |
| ATG7 | autophagy related 7 |
| ATP13A2 | ATPase type 13A2 |
| B4GALT2 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 |
| BCL9 | B-cell CLL/lymphoma 9 |
| BIK | BCL2-interacting killer (apoptosis-inducing) |
| BIN3 | bridging integrator 3 |
| CCDC176 | coiled-coil domain containing 176 |
| CCNL2 | cyclin L2 |
| CCRN4L | CCR4 carbon catabolite repression 4-like (S. cerevisiae) |
| CCS | copper chaperone for superoxide dismutase |
| CD83 | CD83 molecule |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CHKB | choline kinase beta |
| CHML | choroideremia-like (Rab escort protein 2) |
| CHMP1A | charged multivesicular body protein 1A |
| CLK2 | CDC-like kinase 2 |
| CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
| CTC1 | CTS telomere maintenance complex component 1 |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| DENND4A | DENN/MADD domain containing 4A |
| DPF2 | D4, zinc and double PHD fingers family 2 |
| DUSP2 | dual specificity phosphatase 2 |
| EHHADH | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FGGY | FGGY carbohydrate kinase domain containing |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 |
| FMO4 | flavin containing monooxygenase 4 |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 |
| GNL1 | guanine nucleotide binding protein-like 1 |
| HDAC4 | histone deacetylase 4 |
| HIST1H2BC | histone cluster 1, H2bc |
| HIST1H3G | histone cluster 1, H3g |
| HIST1H4D | histone cluster 1, H4d |
| HMG20A | high mobility group 20A |
| INF2 | inverted formin, FH2 and WH2 domain containing |
| IRAK4 | interleukin-1 receptor-associated kinase 4 |
| ITPKB | inositol-trisphosphate 3-kinase B |
| KAT2A | K(lysine) acetyltransferase 2A |
| LAMA3 | laminin, alpha 3 |
| LINC00115 | long intergenic non-protein coding RNA 115 |
| LRP5 | low density lipoprotein receptor-related protein 5 |
| MAP1S | microtubule-associated protein 1S |
| MBTD1 | mbt domain containing 1 |
| MINOS1P1 | mitochondrial inner membrane organizing system 1 pseudogene 1 |
| MPI | mannose phosphate isomerase |
| MTRF1 | mitochondrial translational release factor 1 |
| MYL5 | myosin, light chain 5, regulatory |
| NFE2L3 | nuclear factor, erythroid 2-like 3 |
| NKAIN1 | Na+/K+ transporting ATPase interacting 1 |
| NLRX1 | NLR family member X1 |
| NUBPL | nucleotide binding protein-like |
| ONECUT2 | one cut homeobox 2 |
| P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 |
| PCNXL4 | pecanex-like 4 (Drosophila) |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PGBD5 | piggyBac transposable element derived 5 |
| PKN1 | protein kinase N1 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| POLD1 | polymerase (DNA directed), delta 1, catalytic subunit |
| PPT2 | palmitoyl-protein thioesterase 2 |
| PREX2 | phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 |
| PRRG1 | proline rich Gla (G-carboxyglutamic acid) 1 |
| RAB4B | RAB4B, member RAS oncogene family |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
| RFX7 | regulatory factor X, 7 |
| RNF2 | ring finger protein 2 |
| RNF43 | ring finger protein 43 |
| RPUSD2 | RNA pseudouridylate synthase domain containing 2 |
| SCD5 | stearoyl-CoA desaturase 5 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) |
| SEC61A2 | Sec61 alpha 2 subunit (S. cerevisiae) |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SH2D4A | SH2 domain containing 4A |
| SND1 | staphylococcal nuclease and tudor domain containing 1 |
| SOX12 | SRY (sex determining region Y)-box 12 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TNNT1 | troponin T type 1 (skeletal, slow) |
| TPST2 | tyrosylprotein sulfotransferase 2 |
| TRIM66 | tripartite motif containing 66 |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| VGF | VGF nerve growth factor inducible |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| WDR19 | WD repeat domain 19 |
| WDR62 | WD repeat domain 62 |
| XPNPEP3 | X-prolyl aminopeptidase 3, mitochondrial |
| ZBED1 | zinc finger, BED-type containing 1 |
| ZDHHC11 | zinc finger, DHHC-type containing 11 |
| ZNF394 | zinc finger protein 394 |
| ZNF696 | zinc finger protein 696 |
| ZXDC | ZXD family zinc finger C |
