| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the bupivacaine-7435 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase |
| ADAP2 | ArfGAP with dual PH domains 2 |
| ADRBK1 | adrenergic, beta, receptor kinase 1 |
| ADRBK2 | adrenergic, beta, receptor kinase 2 |
| AGMAT | agmatine ureohydrolase (agmatinase) |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| ARFRP1 | ADP-ribosylation factor related protein 1 |
| ATP2A3 | ATPase, Ca++ transporting, ubiquitous |
| BAG4 | BCL2-associated athanogene 4 |
| BCL3 | B-cell CLL/lymphoma 3 |
| BIN1 | bridging integrator 1 |
| BMP4 | bone morphogenetic protein 4 |
| CCS | copper chaperone for superoxide dismutase |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) |
| CEP350 | centrosomal protein 350kDa |
| CHKB | choline kinase beta |
| CHPF2 | chondroitin polymerizing factor 2 |
| COA1 | cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae) |
| COL5A1 | collagen, type V, alpha 1 |
| COQ7 | coenzyme Q7 homolog, ubiquinone (yeast) |
| CSNK2A1 | casein kinase 2, alpha 1 polypeptide |
| CTDSP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 |
| CTIF | CBP80/20-dependent translation initiation factor |
| CUL2 | cullin 2 |
| CYHR1 | cysteine/histidine-rich 1 |
| DIO2 | deiodinase, iodothyronine, type II |
| DOK4 | docking protein 4 |
| DTNA | dystrobrevin, alpha |
| DUSP13 | dual specificity phosphatase 13 |
| EHBP1L1 | EH domain binding protein 1-like 1 |
| EHD1 | EH-domain containing 1 |
| EPHA2 | EPH receptor A2 |
| EPN2 | epsin 2 |
| EXOC7 | exocyst complex component 7 |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 |
| FGFR4 | fibroblast growth factor receptor 4 |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| HCFC1 | host cell factor C1 |
| HDAC4 | histone deacetylase 4 |
| HIST1H4C | histone cluster 1, H4c |
| HTT | huntingtin |
| IFT140 | intraflagellar transport 140 |
| IL15RA | interleukin 15 receptor, alpha |
| IL4R | interleukin 4 receptor |
| INO80B | INO80 complex subunit B |
| KDM7A | lysine (K)-specific demethylase 7A |
| KLF3 | Kruppel-like factor 3 (basic) |
| KLHDC3 | kelch domain containing 3 |
| KLHL26 | kelch-like family member 26 |
| LONP2 | lon peptidase 2, peroxisomal |
| LPIN2 | lipin 2 |
| LRRC61 | leucine rich repeat containing 61 |
| MAPRE3 | microtubule-associated protein, RP/EB family, member 3 |
| MECP2 | methyl CpG binding protein 2 |
| MPDZ | multiple PDZ domain protein |
| MTERF4 | mitochondrial transcription termination factor 4 |
| MVB12B | multivesicular body subunit 12B |
| NAB2 | NGFI-A binding protein 2 (EGR1 binding protein 2) |
| NDE1 | nudE neurodevelopment protein 1 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 |
| NF1 | neurofibromin 1 |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 |
| PCDHA5 | protocadherin alpha 5 |
| PDK2 | pyruvate dehydrogenase kinase, isozyme 2 |
| PHF20L1 | PHD finger protein 20-like 1 |
| PILRB | paired immunoglobin-like type 2 receptor beta |
| POLL | polymerase (DNA directed), lambda |
| PPAN | peter pan homolog (Drosophila) |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PTRF | polymerase I and transcript release factor |
| R3HDM4 | R3H domain containing 4 |
| RAB11FIP3 | RAB11 family interacting protein 3 (class II) |
| RARA | retinoic acid receptor, alpha |
| RASAL1 | RAS protein activator like 1 (GAP1 like) |
| RPL37A | ribosomal protein L37a |
| S100A6 | S100 calcium binding protein A6 |
| SETD4 | SET domain containing 4 |
| SIRT3 | sirtuin 3 |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SNAPC4 | small nuclear RNA activating complex, polypeptide 4, 190kDa |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) |
| SOX13 | SRY (sex determining region Y)-box 13 |
| SOX4 | SRY (sex determining region Y)-box 4 |
| SPHK1 | sphingosine kinase 1 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 |
| SRCAP | Snf2-related CREBBP activator protein |
| ST3GAL4 | ST3 beta-galactoside alpha-2,3-sialyltransferase 4 |
| TAF6L | TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa |
| TICAM1 | toll-like receptor adaptor molecule 1 |
| TLE2 | transducin-like enhancer of split 2 |
| TMPRSS3 | transmembrane protease, serine 3 |
| TREX1 | three prime repair exonuclease 1 |
| TXNRD2 | thioredoxin reductase 2 |
| UNC93B1 | unc-93 homolog B1 (C. elegans) |
| UPK3B | uroplakin 3B |
| WWP2 | WW domain containing E3 ubiquitin protein ligase 2 |
| ZER1 | zyg-11 related, cell cycle regulator |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
| ZNF93 | zinc finger protein 93 |
| Symbol | Name |
|---|---|
| ABLIM3 | actin binding LIM protein family, member 3 |
| AMFR | autocrine motility factor receptor, E3 ubiquitin protein ligase |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| APH1A | APH1A gamma secretase subunit |
| ARHGEF1 | Rho guanine nucleotide exchange factor (GEF) 1 |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| BAX | BCL2-associated X protein |
| BBC3 | BCL2 binding component 3 |
| C19ORF40 | chromosome 19 open reading frame 40 |
| C1ORF159 | chromosome 1 open reading frame 159 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CASZ1 | castor zinc finger 1 |
| CCDC186 | coiled-coil domain containing 186 |
| CCDC6 | coiled-coil domain containing 6 |
| CCDC85C | coiled-coil domain containing 85C |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 |
| CHST12 | carbohydrate (chondroitin 4) sulfotransferase 12 |
| CLSPN | claspin |
| CTC1 | CTS telomere maintenance complex component 1 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa |
| DAZAP1 | DAZ associated protein 1 |
| DCAF13 | DDB1 and CUL4 associated factor 13 |
| DLST | dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) |
| DNAJC17 | DnaJ (Hsp40) homolog, subfamily C, member 17 |
| EAF2 | ELL associated factor 2 |
| ECHDC3 | enoyl CoA hydratase domain containing 3 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 |
| EPPK1 | epiplakin 1 |
| ETAA1 | Ewing tumor-associated antigen 1 |
| FAM131A | family with sequence similarity 131, member A |
| FAM86C1 | family with sequence similarity 86, member C1 |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FKBP14 | FK506 binding protein 14, 22 kDa |
| FRS2 | fibroblast growth factor receptor substrate 2 |
| GALNT14 | polypeptide N-acetylgalactosaminyltransferase 14 |
| GATAD2A | GATA zinc finger domain containing 2A |
| GATC | glutamyl-tRNA(Gln) amidotransferase, subunit C |
| GDAP1 | ganglioside induced differentiation associated protein 1 |
| GLI3 | GLI family zinc finger 3 |
| GPRASP1 | G protein-coupled receptor associated sorting protein 1 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| H1F0 | H1 histone family, member 0 |
| HIRA | histone cell cycle regulator |
| HIST1H1C | histone cluster 1, H1c |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H2AI | histone cluster 1, H2ai |
| HIST1H2AJ | histone cluster 1, H2aj |
| IRF7 | interferon regulatory factor 7 |
| KIFC1 | kinesin family member C1 |
| LAMA3 | laminin, alpha 3 |
| LMNB1 | lamin B1 |
| MFSD11 | major facilitator superfamily domain containing 11 |
| MGA | MGA, MAX dimerization protein |
| MSL2 | male-specific lethal 2 homolog (Drosophila) |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| PAFAH1B2 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) |
| PARPBP | PARP1 binding protein |
| PDIA3 | protein disulfide isomerase family A, member 3 |
| PEX26 | peroxisomal biogenesis factor 26 |
| PFDN6 | prefoldin subunit 6 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PTDSS2 | phosphatidylserine synthase 2 |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| RNF121 | ring finger protein 121 |
| RNF146 | ring finger protein 146 |
| RNF2 | ring finger protein 2 |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 |
| SH3BGR | SH3 domain binding glutamate-rich protein |
| SLC39A7 | solute carrier family 39 (zinc transporter), member 7 |
| SNORA21 | small nucleolar RNA, H/ACA box 21 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 |
| SREK1IP1 | SREK1-interacting protein 1 |
| STBD1 | starch binding domain 1 |
| STK16 | serine/threonine kinase 16 |
| TAF13 | TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TAF5L | TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa |
| TCTN1 | tectonic family member 1 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) |
| TET3 | tet methylcytosine dioxygenase 3 |
| THRAP3 | thyroid hormone receptor associated protein 3 |
| TMEM159 | transmembrane protein 159 |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 |
| TRIM25 | tripartite motif containing 25 |
| TRPM4 | transient receptor potential cation channel, subfamily M, member 4 |
| TSC22D4 | TSC22 domain family, member 4 |
| TUBA3C | tubulin, alpha 3c |
| VASH2 | vasohibin 2 |
| WDR76 | WD repeat domain 76 |
| ZBTB6 | zinc finger and BTB domain containing 6 |
| ZNF205 | zinc finger protein 205 |
| ZNF428 | zinc finger protein 428 |
| ZNF480 | zinc finger protein 480 |
| ZSCAN26 | zinc finger and SCAN domain containing 26 |
