| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the bupropion-6256 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| APBA1 | amyloid beta (A4) precursor protein-binding, family A, member 1 |
| ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
| ATP9A | ATPase, class II, type 9A |
| BMP5 | bone morphogenetic protein 5 |
| BST2 | bone marrow stromal cell antigen 2 |
| CA5B | carbonic anhydrase VB, mitochondrial |
| CACNA1G | calcium channel, voltage-dependent, T type, alpha 1G subunit |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase |
| CD58 | CD58 molecule |
| CFHR2 | complement factor H-related 2 |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| CHMP6 | charged multivesicular body protein 6 |
| CLPS | colipase, pancreatic |
| CLSTN3 | calsyntenin 3 |
| COL5A1 | collagen, type V, alpha 1 |
| CRYBB2P1 | crystallin, beta B2 pseudogene 1 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 |
| DIAPH1 | diaphanous-related formin 1 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 |
| ELK1 | ELK1, member of ETS oncogene family |
| ENTPD1 | ectonucleoside triphosphate diphosphohydrolase 1 |
| EPS8L1 | EPS8-like 1 |
| ERG | v-ets avian erythroblastosis virus E26 oncogene homolog |
| EVA1B | eva-1 homolog B (C. elegans) |
| EVI5 | ecotropic viral integration site 5 |
| EXO5 | exonuclease 5 |
| FAIM2 | Fas apoptotic inhibitory molecule 2 |
| FAM134B | family with sequence similarity 134, member B |
| FBXO31 | F-box protein 31 |
| FER | fer (fps/fes related) tyrosine kinase |
| FNDC3A | fibronectin type III domain containing 3A |
| GABBR2 | gamma-aminobutyric acid (GABA) B receptor, 2 |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GPC3 | glypican 3 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 |
| GSTCD | glutathione S-transferase, C-terminal domain containing |
| GYG2 | glycogenin 2 |
| HIC2 | hypermethylated in cancer 2 |
| HOXC10 | homeobox C10 |
| HOXC11 | homeobox C11 |
| ICAM1 | intercellular adhesion molecule 1 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IFITM1 | interferon induced transmembrane protein 1 |
| INO80D | INO80 complex subunit D |
| IQSEC2 | IQ motif and Sec7 domain 2 |
| IRF9 | interferon regulatory factor 9 |
| ISG15 | ISG15 ubiquitin-like modifier |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
| KLHL28 | kelch-like family member 28 |
| KLK5 | kallikrein-related peptidase 5 |
| KRT6B | keratin 6B, type II |
| LOC284244 | uncharacterized LOC284244 |
| LPIN2 | lipin 2 |
| LRRC23 | leucine rich repeat containing 23 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MAP4 | microtubule-associated protein 4 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MMRN2 | multimerin 2 |
| MXD4 | MAX dimerization protein 4 |
| MYOF | myoferlin |
| NPFFR1 | neuropeptide FF receptor 1 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa |
| ONECUT1 | one cut homeobox 1 |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PCLO | piccolo presynaptic cytomatrix protein |
| PDE3B | phosphodiesterase 3B, cGMP-inhibited |
| PDGFA | platelet-derived growth factor alpha polypeptide |
| PIP5K1C | phosphatidylinositol-4-phosphate 5-kinase, type I, gamma |
| PKLR | pyruvate kinase, liver and RBC |
| PLCD1 | phospholipase C, delta 1 |
| PLK4 | polo-like kinase 4 |
| PLSCR3 | phospholipid scramblase 3 |
| POLR2J4 | polymerase (RNA) II (DNA directed) polypeptide J4, pseudogene |
| PTCH2 | patched 2 |
| QKI | QKI, KH domain containing, RNA binding |
| RAB6B | RAB6B, member RAS oncogene family |
| REST | RE1-silencing transcription factor |
| SEMA4F | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F |
| SFTPA2 | surfactant protein A2 |
| SH3BP2 | SH3-domain binding protein 2 |
| SLC15A2 | solute carrier family 15 (oligopeptide transporter), member 2 |
| SP110 | SP110 nuclear body protein |
| SPPL2B | signal peptide peptidase like 2B |
| STAB2 | stabilin 2 |
| STK3 | serine/threonine kinase 3 |
| SUGP1 | SURP and G patch domain containing 1 |
| SUN1 | Sad1 and UNC84 domain containing 1 |
| TIMM17A | translocase of inner mitochondrial membrane 17 homolog A (yeast) |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 |
| UBE3A | ubiquitin protein ligase E3A |
| UEVLD | UEV and lactate/malate dehyrogenase domains |
| VAMP4 | vesicle-associated membrane protein 4 |
| VPS39 | vacuolar protein sorting 39 homolog (S. cerevisiae) |
| WDR62 | WD repeat domain 62 |
| ZBTB48 | zinc finger and BTB domain containing 48 |
| ZER1 | zyg-11 related, cell cycle regulator |
| ZNF771 | zinc finger protein 771 |
| Symbol | Name |
|---|---|
| AEN | apoptosis enhancing nuclease |
| AKT1 | v-akt murine thymoma viral oncogene homolog 1 |
| AKTIP | AKT interacting protein |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| ANXA2P3 | annexin A2 pseudogene 3 |
| AXIN1 | axin 1 |
| BAX | BCL2-associated X protein |
| BBS7 | Bardet-Biedl syndrome 7 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CDR2L | cerebellar degeneration-related protein 2-like |
| CHST7 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 |
| CLCN5 | chloride channel, voltage-sensitive 5 |
| CNKSR1 | connector enhancer of kinase suppressor of Ras 1 |
| COBL | cordon-bleu WH2 repeat protein |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
| CWC25 | CWC25 spliceosome-associated protein homolog (S. cerevisiae) |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DVL1 | dishevelled segment polarity protein 1 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 |
| EIF5A2 | eukaryotic translation initiation factor 5A2 |
| EPPK1 | epiplakin 1 |
| FGGY | FGGY carbohydrate kinase domain containing |
| FIP1L1 | factor interacting with PAPOLA and CPSF1 |
| FLT4 | fms-related tyrosine kinase 4 |
| FOSL1 | FOS-like antigen 1 |
| FYCO1 | FYVE and coiled-coil domain containing 1 |
| GADD45G | growth arrest and DNA-damage-inducible, gamma |
| GATB | glutamyl-tRNA(Gln) amidotransferase, subunit B |
| GLB1L2 | galactosidase, beta 1-like 2 |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GNE | glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GRINA | glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HINFP | histone H4 transcription factor |
| HIRA | histone cell cycle regulator |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 |
| HMHA1 | histocompatibility (minor) HA-1 |
| HOXA5 | homeobox A5 |
| IL12RB1 | interleukin 12 receptor, beta 1 |
| IL15RA | interleukin 15 receptor, alpha |
| IMPACT | impact RWD domain protein |
| IPO13 | importin 13 |
| IRF6 | interferon regulatory factor 6 |
| KCNMB3 | potassium channel subfamily M regulatory beta subunit 3 |
| LRRC8E | leucine rich repeat containing 8 family, member E |
| MBTD1 | mbt domain containing 1 |
| MC1R | melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) |
| METTL21B | methyltransferase like 21B |
| MFSD12 | major facilitator superfamily domain containing 12 |
| MNX1 | motor neuron and pancreas homeobox 1 |
| MTCL1 | microtubule crosslinking factor 1 |
| MTHFSD | methenyltetrahydrofolate synthetase domain containing |
| NDE1 | nudE neurodevelopment protein 1 |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| OSMR | oncostatin M receptor |
| PARG | poly (ADP-ribose) glycohydrolase |
| PCNXL4 | pecanex-like 4 (Drosophila) |
| PGBD5 | piggyBac transposable element derived 5 |
| PILRB | paired immunoglobin-like type 2 receptor beta |
| POMT2 | protein-O-mannosyltransferase 2 |
| PRRG1 | proline rich Gla (G-carboxyglutamic acid) 1 |
| PTCD2 | pentatricopeptide repeat domain 2 |
| RAB5B | RAB5B, member RAS oncogene family |
| RANBP17 | RAN binding protein 17 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 |
| RBL1 | retinoblastoma-like 1 |
| RCBTB1 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1 |
| RGS17 | regulator of G-protein signaling 17 |
| RPAIN | RPA interacting protein |
| RPAP1 | RNA polymerase II associated protein 1 |
| RPL23AP7 | ribosomal protein L23a pseudogene 7 |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SECTM1 | secreted and transmembrane 1 |
| SEZ6L2 | seizure related 6 homolog (mouse)-like 2 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 |
| SLC25A40 | solute carrier family 25, member 40 |
| SLC36A1 | solute carrier family 36 (proton/amino acid symporter), member 1 |
| SPATA7 | spermatogenesis associated 7 |
| STBD1 | starch binding domain 1 |
| SYCP2 | synaptonemal complex protein 2 |
| TAGLN | transgelin |
| TMEM2 | transmembrane protein 2 |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| UBQLN4 | ubiquilin 4 |
| UBXN2B | UBX domain protein 2B |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 |
| ULBP2 | UL16 binding protein 2 |
| WLS | wntless Wnt ligand secretion mediator |
| XRCC1 | X-ray repair complementing defective repair in Chinese hamster cells 1 |
| ZNF219 | zinc finger protein 219 |
| ZNF430 | zinc finger protein 430 |
| ZNF586 | zinc finger protein 586 |
| ZNF672 | zinc finger protein 672 |
| ZNF74 | zinc finger protein 74 |
| ZNF768 | zinc finger protein 768 |
| ZNF787 | zinc finger protein 787 |
| ZNF813 | zinc finger protein 813 |
