burden Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

159 genes co-occuring with the biological term burden in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCG8 ATP-binding cassette, sub-family G (WHITE), member 8
ACO1 aconitase 1, soluble
ADIPOQ adiponectin, C1Q and collagen domain containing
AGER advanced glycosylation end product-specific receptor
ALAD aminolevulinate dehydratase
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ANGPT2 angiopoietin 2
APC adenomatous polyposis coli
APOA1 apolipoprotein A-I
APOB apolipoprotein B
APOE apolipoprotein E
APP amyloid beta (A4) precursor protein
AR androgen receptor
B2M beta-2-microglobulin
BDNF brain-derived neurotrophic factor
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
CALR calreticulin
CCL17 chemokine (C-C motif) ligand 17
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
CCL2 chemokine (C-C motif) ligand 2
CCND3 cyclin D3
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD163 CD163 molecule
CD36 CD36 molecule (thrombospondin receptor)
CD40LG CD40 ligand
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CFI complement factor I
CHGA chromogranin A
CLLU1 chronic lymphocytic leukemia up-regulated 1
CLU clusterin
COMP cartilage oligomeric matrix protein
CP ceruloplasmin (ferroxidase)
CPB2 carboxypeptidase B2 (plasma)
CRP C-reactive protein, pentraxin-related
CST3 cystatin C
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CUX1 cut-like homeobox 1
CXCL13 chemokine (C-X-C motif) ligand 13
CXCL9 chemokine (C-X-C motif) ligand 9
CXCR4 chemokine (C-X-C motif) receptor 4
CYBB cytochrome b-245, beta polypeptide
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
ECHDC1 ethylmalonyl-CoA decarboxylase 1
EDN1 endothelin 1
ERBB2 erb-b2 receptor tyrosine kinase 2
ESR1 estrogen receptor 1
EXT1 exostosin glycosyltransferase 1
EXT2 exostosin glycosyltransferase 2
FABP4 fatty acid binding protein 4, adipocyte
FLT3 fms-related tyrosine kinase 3
FTH1 ferritin, heavy polypeptide 1
FTL ferritin, light polypeptide
GATA3 GATA binding protein 3
GGT2 gamma-glutamyltransferase 2
GP1BA glycoprotein Ib (platelet), alpha polypeptide
GRP gastrin-releasing peptide
GSK3B glycogen synthase kinase 3 beta
HAMP hepcidin antimicrobial peptide
HAVCR2 hepatitis A virus cellular receptor 2
HBA1 hemoglobin, alpha 1
HDAC6 histone deacetylase 6
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HMGB1 high mobility group box 1
HMGN1 high mobility group nucleosome binding domain 1
HMOX1 heme oxygenase 1
HRAS Harvey rat sarcoma viral oncogene homolog
HSPA4 heat shock 70kDa protein 4
HSPD1 heat shock 60kDa protein 1 (chaperonin)
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
HTT huntingtin
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
IFI27 interferon, alpha-inducible protein 27
IFNA1 interferon, alpha 1
IFNB1 interferon, beta 1, fibroblast
IGF1 insulin-like growth factor 1 (somatomedin C)
IGFBP3 insulin-like growth factor binding protein 3
IL10 interleukin 10
IL17A interleukin 17A
IL17F interleukin 17F
IL4 interleukin 4
IL6 interleukin 6
IREB2 iron-responsive element binding protein 2
JAK2 Janus kinase 2
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
KIR3DL2 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KL klotho
KRT9 keratin 9, type I
LPA lipoprotein, Lp(a)
MAN2C1 mannosidase, alpha, class 2C, member 1
MAPT microtubule-associated protein tau
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MEIS1 Meis homeobox 1
MIR326 microRNA 326
MIR96 microRNA 96
MLH1 mutL homolog 1
MMP2 matrix metallopeptidase 2
MMP3 matrix metallopeptidase 3
MMP8 matrix metallopeptidase 8
MMP9 matrix metallopeptidase 9
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MUC1 mucin 1, cell surface associated
MYD88 myeloid differentiation primary response 88
MYH9 myosin, heavy chain 9, non-muscle
NF1 neurofibromin 1
NPHP1 nephronophthisis 1 (juvenile)
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NPPB natriuretic peptide B
NPY neuropeptide Y
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
OXT oxytocin/neurophysin I prepropeptide
P2RY12 purinergic receptor P2Y, G-protein coupled, 12
PDCD1 programmed cell death 1
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PSEN1 presenilin 1
PTPRC protein tyrosine phosphatase, receptor type, C
RNF146 ring finger protein 146
S100A6 S100 calcium binding protein A6
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SFTPB surfactant protein B
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2
SLC40A1 solute carrier family 40 (iron-regulated transporter), member 1
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SMAD3 SMAD family member 3
SMAD7 SMAD family member 7
SOD1 superoxide dismutase 1, soluble
SOD3 superoxide dismutase 3, extracellular
SPP1 secreted phosphoprotein 1
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5A signal transducer and activator of transcription 5A
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
TARDBP TAR DNA binding protein
TERT telomerase reverse transcriptase
TFRC transferrin receptor
TGFB1 transforming growth factor, beta 1
TIMP1 TIMP metallopeptidase inhibitor 1
TLR9 toll-like receptor 9
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TP53 tumor protein p53
VEGFA vascular endothelial growth factor A
VIM vimentin
VWF von Willebrand factor
WIF1 WNT inhibitory factor 1