buspirone-1282 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the buspirone-1282 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTR5 ARP5 actin-related protein 5 homolog (yeast)
AKAP13 A kinase (PRKA) anchor protein 13
APOE apolipoprotein E
ARL4C ADP-ribosylation factor-like 4C
ARPC4 actin related protein 2/3 complex, subunit 4, 20kDa
ATF5 activating transcription factor 5
ATP11A ATPase, class VI, type 11A
ATP13A3 ATPase type 13A3
ATP2A3 ATPase, Ca++ transporting, ubiquitous
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1
ATP9B ATPase, class II, type 9B
BAHCC1 BAH domain and coiled-coil containing 1
BBS4 Bardet-Biedl syndrome 4
BCAT1 branched chain amino-acid transaminase 1, cytosolic
CAPN2 calpain 2, (m/II) large subunit
CCNT2 cyclin T2
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CEP97 centrosomal protein 97kDa
CLEC4A C-type lectin domain family 4, member A
COPA coatomer protein complex, subunit alpha
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CRYZ crystallin, zeta (quinone reductase)
CTSZ cathepsin Z
CYB561 cytochrome b561
DBT dihydrolipoamide branched chain transacylase E2
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DNAL4 dynein, axonemal, light chain 4
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
EPHB6 EPH receptor B6
ERCC4 excision repair cross-complementation group 4
ERN1 endoplasmic reticulum to nucleus signaling 1
FBXW11 F-box and WD repeat domain containing 11
FCAR Fc fragment of IgA receptor
FLOT1 flotillin 1
FLOT2 flotillin 2
FNTB farnesyltransferase, CAAX box, beta
GNS glucosamine (N-acetyl)-6-sulfatase
GOSR2 golgi SNAP receptor complex member 2
GSTT1 glutathione S-transferase theta 1
HIST1H2BD histone cluster 1, H2bd
IFT27 intraflagellar transport 27
IL1RAP interleukin 1 receptor accessory protein
INO80D INO80 complex subunit D
KANK1 KN motif and ankyrin repeat domains 1
KCTD20 potassium channel tetramerization domain containing 20
KLF5 Kruppel-like factor 5 (intestinal)
KLHL20 kelch-like family member 20
KYNU kynureninase
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial)
LIG4 ligase IV, DNA, ATP-dependent
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
LINS lines homolog (Drosophila)
MCL1 myeloid cell leukemia 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MFN2 mitofusin 2
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MPZL1 myelin protein zero-like 1
MRPS12 mitochondrial ribosomal protein S12
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTMR2 myotubularin related protein 2
MUL1 mitochondrial E3 ubiquitin protein ligase 1
N6AMT1 N-6 adenine-specific DNA methyltransferase 1 (putative)
NCOA3 nuclear receptor coactivator 3
NCR2 natural cytotoxicity triggering receptor 2
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NFYC nuclear transcription factor Y, gamma
NKTR natural killer cell triggering receptor
NRP1 neuropilin 1
PCGF2 polycomb group ring finger 2
PCM1 pericentriolar material 1
PHC1 polyhomeotic homolog 1 (Drosophila)
PRSS12 protease, serine, 12 (neurotrypsin, motopsin)
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1
RAB11B RAB11B, member RAS oncogene family
RCAN1 regulator of calcineurin 1
RIN1 Ras and Rab interactor 1
RNF126P1 ring finger protein 126 pseudogene 1
RPS14 ribosomal protein S14
RUNX1 runt-related transcription factor 1
SIN3B SIN3 transcription regulator family member B
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5
SPAG4 sperm associated antigen 4
STAG3L4 stromal antigen 3-like 4 (pseudogene)
SUGP1 SURP and G patch domain containing 1
TGFBR1 transforming growth factor, beta receptor 1
TMEM134 transmembrane protein 134
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TOX4 TOX high mobility group box family member 4
UTRN utrophin
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
VCAN versican
VDAC3 voltage-dependent anion channel 3
WSB1 WD repeat and SOCS box containing 1
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
YY1 YY1 transcription factor
ZBTB6 zinc finger and BTB domain containing 6
ZNF286A zinc finger protein 286A
ZNF76 zinc finger protein 76

decreased expression

Symbol Name
ACVR2B activin A receptor, type IIB
ANAPC2 anaphase promoting complex subunit 2
ANKRD36 ankyrin repeat domain 36
ARFIP2 ADP-ribosylation factor interacting protein 2
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ASB8 ankyrin repeat and SOCS box containing 8
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
AUH AU RNA binding protein/enoyl-CoA hydratase
BAK1 BCL2-antagonist/killer 1
BRPF1 bromodomain and PHD finger containing, 1
C10ORF88 chromosome 10 open reading frame 88
C11ORF68 chromosome 11 open reading frame 68
C17ORF70 chromosome 17 open reading frame 70
C19ORF40 chromosome 19 open reading frame 40
C5AR1 complement component 5a receptor 1
C6ORF47 chromosome 6 open reading frame 47
CAPN1 calpain 1, (mu/I) large subunit
CAPN15 calpain 15
CCDC88C coiled-coil domain containing 88C
CCDC91 coiled-coil domain containing 91
CCRL2 chemokine (C-C motif) receptor-like 2
CHD8 chromodomain helicase DNA binding protein 8
CLSPN claspin
CRYBB2P1 crystallin, beta B2 pseudogene 1
CTDNEP1 CTD nuclear envelope phosphatase 1
DPY19L2P2 DPY19L2 pseudogene 2
ERN2 endoplasmic reticulum to nucleus signaling 2
FCGRT Fc fragment of IgG, receptor, transporter, alpha
FES FES proto-oncogene, tyrosine kinase
FHL3 four and a half LIM domains 3
FHOD1 formin homology 2 domain containing 1
FIP1L1 factor interacting with PAPOLA and CPSF1
GFI1 growth factor independent 1 transcription repressor
GNA12 guanine nucleotide binding protein (G protein) alpha 12
GPRC5C G protein-coupled receptor, class C, group 5, member C
GRWD1 glutamate-rich WD repeat containing 1
HINFP histone H4 transcription factor
HP haptoglobin
IGFLR1 IGF-like family receptor 1
IL24 interleukin 24
KIAA0753 KIAA0753
KIN Kin17 DNA and RNA binding protein
LMNB1 lamin B1
LPAR4 lysophosphatidic acid receptor 4
MAPKAP1 mitogen-activated protein kinase associated protein 1
MAST3 microtubule associated serine/threonine kinase 3
MCRS1 microspherule protein 1
MGMT O-6-methylguanine-DNA methyltransferase
MICALL2 MICAL-like 2
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MON1B MON1 secretory trafficking family member B
MRGBP MRG/MORF4L binding protein
MRPL28 mitochondrial ribosomal protein L28
NAT6 N-acetyltransferase 6 (GCN5-related)
NBEAL2 neurobeachin-like 2
NDE1 nudE neurodevelopment protein 1
NRGN neurogranin (protein kinase C substrate, RC3)
NSMF NMDA receptor synaptonuclear signaling and neuronal migration factor
PAQR4 progestin and adipoQ receptor family member IV
PAQR6 progestin and adipoQ receptor family member VI
PCOLCE2 procollagen C-endopeptidase enhancer 2
PIAS3 protein inhibitor of activated STAT, 3
PIP4K2C phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
PJA1 praja ring finger 1, E3 ubiquitin protein ligase
PNPLA6 patatin-like phospholipase domain containing 6
POLR1B polymerase (RNA) I polypeptide B, 128kDa
POLR3F polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa
PRAF2 PRA1 domain family, member 2
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
PWP2 PWP2 periodic tryptophan protein homolog (yeast)
RALA v-ral simian leukemia viral oncogene homolog A (ras related)
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RNF31 ring finger protein 31
RPA4 replication protein A4, 30kDa
RPP38 ribonuclease P/MRP 38kDa subunit
RPS21 ribosomal protein S21
RSAD1 radical S-adenosyl methionine domain containing 1
SARS2 seryl-tRNA synthetase 2, mitochondrial
SETD8 SET domain containing (lysine methyltransferase) 8
SIRT2 sirtuin 2
SKI SKI proto-oncogene
SNHG3 small nucleolar RNA host gene 3
SPI1 Spi-1 proto-oncogene
SPON2 spondin 2, extracellular matrix protein
STAG3L1 stromal antigen 3-like 1 (pseudogene)
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
TERT telomerase reverse transcriptase
TM7SF2 transmembrane 7 superfamily member 2
TMEM184B transmembrane protein 184B
TRIP10 thyroid hormone receptor interactor 10
TUBB6 tubulin, beta 6 class V
UBQLN4 ubiquilin 4
WT1-AS WT1 antisense RNA
YIPF1 Yip1 domain family, member 1
ZNF350 zinc finger protein 350
ZNF37BP zinc finger protein 37B, pseudogene
ZNF551 zinc finger protein 551
ZNF813 zinc finger protein 813
ZSCAN5A zinc finger and SCAN domain containing 5A