buspirone-5343 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the buspirone-5343 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ALS2CL ALS2 C-terminal like
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2
APC adenomatous polyposis coli
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ARL2BP ADP-ribosylation factor-like 2 binding protein
ARRB1 arrestin, beta 1
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
B4GALT7 xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7
BCL9 B-cell CLL/lymphoma 9
C17ORF59 chromosome 17 open reading frame 59
C9ORF9 chromosome 9 open reading frame 9
CAMK4 calcium/calmodulin-dependent protein kinase IV
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CD22 CD22 molecule
CD83 CD83 molecule
CDK13 cyclin-dependent kinase 13
CEMIP cell migration inducing protein, hyaluronan binding
CGA glycoprotein hormones, alpha polypeptide
CLCN7 chloride channel, voltage-sensitive 7
CRIP1 cysteine-rich protein 1 (intestinal)
CSF1 colony stimulating factor 1 (macrophage)
CTC1 CTS telomere maintenance complex component 1
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
DLC1 DLC1 Rho GTPase activating protein
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DSC2 desmocollin 2
DSCAM Down syndrome cell adhesion molecule
DUSP5 dual specificity phosphatase 5
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EHMT2 euchromatic histone-lysine N-methyltransferase 2
ERC1 ELKS/RAB6-interacting/CAST family member 1
EXOC7 exocyst complex component 7
FAM212B family with sequence similarity 212, member B
FAM46C family with sequence similarity 46, member C
FBLN1 fibulin 1
FGD1 FYVE, RhoGEF and PH domain containing 1
FSCN1 fascin actin-bundling protein 1
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GTPBP1 GTP binding protein 1
HFE hemochromatosis
HIST1H1D histone cluster 1, H1d
HS1BP3 HCLS1 binding protein 3
HTR1F 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled
IDI2-AS1 IDI2 antisense RNA 1
IDUA iduronidase, alpha-L-
IGHM immunoglobulin heavy constant mu
INPP5B inositol polyphosphate-5-phosphatase, 75kDa
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KDM6B lysine (K)-specific demethylase 6B
KRIT1 KRIT1, ankyrin repeat containing
KRT37 keratin 37, type I
LAMP1 lysosomal-associated membrane protein 1
LOC440895 two pore channel 3 pseudogene
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
LYST lysosomal trafficking regulator
MAP1B microtubule-associated protein 1B
MAP2K5 mitogen-activated protein kinase kinase 5
MFAP3L microfibrillar-associated protein 3-like
MTCP1 mature T-cell proliferation 1
MTM1 myotubularin 1
MZF1 myeloid zinc finger 1
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NKAIN1 Na+/K+ transporting ATPase interacting 1
NR1H2 nuclear receptor subfamily 1, group H, member 2
NR2F6 nuclear receptor subfamily 2, group F, member 6
PAOX polyamine oxidase (exo-N4-amino)
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLK3 polo-like kinase 3
PMS2P2 postmeiotic segregation increased 2 pseudogene 2
PPM1F protein phosphatase, Mg2+/Mn2+ dependent, 1F
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
RAB11B RAB11B, member RAS oncogene family
RAB36 RAB36, member RAS oncogene family
RANBP3 RAN binding protein 3
RCE1 Ras converting CAAX endopeptidase 1
RECQL5 RecQ protein-like 5
RPH3A rabphilin 3A
S100A9 S100 calcium binding protein A9
SCARB1 scavenger receptor class B, member 1
SCGB2A2 secretoglobin, family 2A, member 2
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4
SOGA1 suppressor of glucose, autophagy associated 1
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
SRPX sushi-repeat containing protein, X-linked
TAZ tafazzin
TBC1D22A TBC1 domain family, member 22A
TFF2 trefoil factor 2
TMC5 transmembrane channel-like 5
WSB1 WD repeat and SOCS box containing 1
ZNF34 zinc finger protein 34
ZNF589 zinc finger protein 589
ZNF710 zinc finger protein 710
ZNF750 zinc finger protein 750

decreased expression

Symbol Name
AFF4 AF4/FMR2 family, member 4
AKAP12 A kinase (PRKA) anchor protein 12
AKR1C3 aldo-keto reductase family 1, member C3
ANXA1 annexin A1
ANXA2P3 annexin A2 pseudogene 3
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BRPF1 bromodomain and PHD finger containing, 1
BTF3P12 basic transcription factor 3 pseudogene 12
C11ORF57 chromosome 11 open reading frame 57
C16ORF59 chromosome 16 open reading frame 59
C1ORF159 chromosome 1 open reading frame 159
C3ORF52 chromosome 3 open reading frame 52
C7ORF43 chromosome 7 open reading frame 43
CCDC15 coiled-coil domain containing 15
CHML choroideremia-like (Rab escort protein 2)
CLDN15 claudin 15
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CNNM3 cyclin and CBS domain divalent metal cation transport mediator 3
CORT cortistatin
DHRS11 dehydrogenase/reductase (SDR family) member 11
DVL1 dishevelled segment polarity protein 1
ECHDC3 enoyl CoA hydratase domain containing 3
EDEM1 ER degradation enhancer, mannosidase alpha-like 1
EFHD1 EF-hand domain family, member D1
EFNA3 ephrin-A3
ELOVL4 ELOVL fatty acid elongase 4
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
ERI3 ERI1 exoribonuclease family member 3
FAM53B family with sequence similarity 53, member B
FGD6 FYVE, RhoGEF and PH domain containing 6
FKBP2 FK506 binding protein 2, 13kDa
FMO4 flavin containing monooxygenase 4
FZD2 frizzled class receptor 2
GOLGA8B golgin A8 family, member B
GPX2 glutathione peroxidase 2
HCFC2 host cell factor C2
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HMHA1 histocompatibility (minor) HA-1
HOXC11 homeobox C11
IFI6 interferon, alpha-inducible protein 6
IFT22 intraflagellar transport 22
IL17RB interleukin 17 receptor B
INF2 inverted formin, FH2 and WH2 domain containing
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
IREB2 iron-responsive element binding protein 2
IRF7 interferon regulatory factor 7
IRX4 iroquois homeobox 4
ISG15 ISG15 ubiquitin-like modifier
MAP6D1 MAP6 domain containing 1
MAPK12 mitogen-activated protein kinase 12
MPI mannose phosphate isomerase
MTMR11 myotubularin related protein 11
MXD3 MAX dimerization protein 3
MYO1E myosin IE
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
NDE1 nudE neurodevelopment protein 1
NES nestin
NPFFR1 neuropeptide FF receptor 1
NRGN neurogranin (protein kinase C substrate, RC3)
NUP62CL nucleoporin 62kDa C-terminal like
PAQR6 progestin and adipoQ receptor family member VI
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PKN1 protein kinase N1
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
PLEKHO1 pleckstrin homology domain containing, family O member 1
PRICKLE3 prickle homolog 3 (Drosophila)
PTDSS2 phosphatidylserine synthase 2
PTPRU protein tyrosine phosphatase, receptor type, U
PYCRL pyrroline-5-carboxylate reductase-like
RGS17 regulator of G-protein signaling 17
RIBC2 RIB43A domain with coiled-coils 2
RINT1 RAD50 interactor 1
SGK1 serum/glucocorticoid regulated kinase 1
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28
SMCO4 single-pass membrane protein with coiled-coil domains 4
STK16 serine/threonine kinase 16
SYCP2 synaptonemal complex protein 2
TESK1 testis-specific kinase 1
TMEM184C transmembrane protein 184C
TRABD TraB domain containing
TRIP10 thyroid hormone receptor interactor 10
TUBA3C tubulin, alpha 3c
UBE2L6 ubiquitin-conjugating enzyme E2L 6
VAV1 vav 1 guanine nucleotide exchange factor
VAX2 ventral anterior homeobox 2
WDR91 WD repeat domain 91
ZC3H3 zinc finger CCCH-type containing 3
ZNF134 zinc finger protein 134
ZNF227 zinc finger protein 227
ZNF571 zinc finger protein 571
ZNF574 zinc finger protein 574
ZNF668 zinc finger protein 668