| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the butacaine-2728 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABAT | 4-aminobutyrate aminotransferase |
| ACSF2 | acyl-CoA synthetase family member 2 |
| ADGRB1 | adhesion G protein-coupled receptor B1 |
| ADRB3 | adrenoceptor beta 3 |
| AIF1 | allograft inflammatory factor 1 |
| ALOX15B | arachidonate 15-lipoxygenase, type B |
| ANGPT1 | angiopoietin 1 |
| APBA2 | amyloid beta (A4) precursor protein-binding, family A, member 2 |
| APOBEC1 | apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 |
| CACNG2 | calcium channel, voltage-dependent, gamma subunit 2 |
| CADM3 | cell adhesion molecule 3 |
| CAMP | cathelicidin antimicrobial peptide |
| CD1E | CD1e molecule |
| CDC42EP2 | CDC42 effector protein (Rho GTPase binding) 2 |
| CDCP1 | CUB domain containing protein 1 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) |
| CDY1 | chromodomain protein, Y-linked, 1 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 |
| CEP170B | centrosomal protein 170B |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| COL11A2 | collagen, type XI, alpha 2 |
| COL6A3 | collagen, type VI, alpha 3 |
| CPNE7 | copine VII |
| CRP | C-reactive protein, pentraxin-related |
| CYP2A7 | cytochrome P450, family 2, subfamily A, polypeptide 7 |
| DLC1 | DLC1 Rho GTPase activating protein |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 |
| F11R | F11 receptor |
| FAM110D | family with sequence similarity 110, member D |
| FBXO31 | F-box protein 31 |
| FBXO4 | F-box protein 4 |
| FRS2 | fibroblast growth factor receptor substrate 2 |
| FZD4 | frizzled class receptor 4 |
| GNRH1 | gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) |
| GPX2 | glutathione peroxidase 2 |
| HCRTR2 | hypocretin (orexin) receptor 2 |
| HDAC11 | histone deacetylase 11 |
| HLA-DOA | major histocompatibility complex, class II, DO alpha |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 |
| HOXA6 | homeobox A6 |
| HOXC10 | homeobox C10 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
| HPGDS | hematopoietic prostaglandin D synthase |
| IGHD | immunoglobulin heavy constant delta |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| KCNA6 | potassium channel, voltage gated shaker related subfamily A, member 6 |
| KLC2 | kinesin light chain 2 |
| KLF9 | Kruppel-like factor 9 |
| LAMC3 | laminin, gamma 3 |
| LARGE | like-glycosyltransferase |
| LMF1 | lipase maturation factor 1 |
| LRRC75B | leucine rich repeat containing 75B |
| LRRN3 | leucine rich repeat neuronal 3 |
| MORN1 | MORN repeat containing 1 |
| MUC8 | mucin 8 |
| MYH14 | myosin, heavy chain 14, non-muscle |
| MYL10 | myosin, light chain 10, regulatory |
| NDST1 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 |
| NFIB | nuclear factor I/B |
| NTF3 | neurotrophin 3 |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PLSCR3 | phospholipid scramblase 3 |
| POM121L9P | POM121 transmembrane nucleoporin-like 9, pseudogene |
| PPAP2B | phosphatidic acid phosphatase type 2B |
| PSG11 | pregnancy specific beta-1-glycoprotein 11 |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) |
| RAB11B | RAB11B, member RAS oncogene family |
| RASGRP2 | RAS guanyl releasing protein 2 (calcium and DAG-regulated) |
| RBPMS | RNA binding protein with multiple splicing |
| ROBO3 | roundabout, axon guidance receptor, homolog 3 (Drosophila) |
| RPS6KA6 | ribosomal protein S6 kinase, 90kDa, polypeptide 6 |
| SECTM1 | secreted and transmembrane 1 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A |
| SEMA6B | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B |
| SFRP5 | secreted frizzled-related protein 5 |
| SHB | Src homology 2 domain containing adaptor protein B |
| SLC17A7 | solute carrier family 17 (vesicular glutamate transporter), member 7 |
| SLC5A2 | solute carrier family 5 (sodium/glucose cotransporter), member 2 |
| SPAG11A | sperm associated antigen 11A |
| ST3GAL4 | ST3 beta-galactoside alpha-2,3-sialyltransferase 4 |
| SYT5 | synaptotagmin V |
| TGFB1 | transforming growth factor, beta 1 |
| TGFB3 | transforming growth factor, beta 3 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 |
| TJAP1 | tight junction associated protein 1 (peripheral) |
| TMPRSS2 | transmembrane protease, serine 2 |
| TNFSF18 | tumor necrosis factor (ligand) superfamily, member 18 |
| TP53I11 | tumor protein p53 inducible protein 11 |
| TSPAN9 | tetraspanin 9 |
| USP2 | ubiquitin specific peptidase 2 |
| VPS9D1 | VPS9 domain containing 1 |
| WSCD2 | WSC domain containing 2 |
| ZFYVE9 | zinc finger, FYVE domain containing 9 |
| ZNF440 | zinc finger protein 440 |
| Symbol | Name |
|---|---|
| A4GNT | alpha-1,4-N-acetylglucosaminyltransferase |
| ABHD17B | abhydrolase domain containing 17B |
| ACVR2B | activin A receptor, type IIB |
| AGPAT3 | 1-acylglycerol-3-phosphate O-acyltransferase 3 |
| AIM2 | absent in melanoma 2 |
| ANKH | ANKH inorganic pyrophosphate transport regulator |
| AQP9 | aquaporin 9 |
| ARID5A | AT rich interactive domain 5A (MRF1-like) |
| ARMCX4 | armadillo repeat containing, X-linked 4 |
| ARRB1 | arrestin, beta 1 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) |
| ATP7B | ATPase, Cu++ transporting, beta polypeptide |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase |
| C16ORF45 | chromosome 16 open reading frame 45 |
| C17ORF53 | chromosome 17 open reading frame 53 |
| C19ORF73 | chromosome 19 open reading frame 73 |
| CAMKMT | calmodulin-lysine N-methyltransferase |
| CCDC130 | coiled-coil domain containing 130 |
| CCDC57 | coiled-coil domain containing 57 |
| CD3D | CD3d molecule, delta (CD3-TCR complex) |
| CENPT | centromere protein T |
| CFAP45 | cilia and flagella associated protein 45 |
| CHM | choroideremia (Rab escort protein 1) |
| CHMP1A | charged multivesicular body protein 1A |
| CLCN5 | chloride channel, voltage-sensitive 5 |
| CLIP2 | CAP-GLY domain containing linker protein 2 |
| COMMD10 | COMM domain containing 10 |
| CYP7B1 | cytochrome P450, family 7, subfamily B, polypeptide 1 |
| DBF4B | DBF4 zinc finger B |
| EYA3 | EYA transcriptional coactivator and phosphatase 3 |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FANCC | Fanconi anemia, complementation group C |
| FGL1 | fibrinogen-like 1 |
| FKBP9 | FK506 binding protein 9, 63 kDa |
| FOXD1 | forkhead box D1 |
| FOXD2 | forkhead box D2 |
| FZD6 | frizzled class receptor 6 |
| GDPD3 | glycerophosphodiester phosphodiesterase domain containing 3 |
| GK3P | glycerol kinase 3 pseudogene |
| GNG3 | guanine nucleotide binding protein (G protein), gamma 3 |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GPATCH2L | G patch domain containing 2-like |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| GRIP2 | glutamate receptor interacting protein 2 |
| GSTT1 | glutathione S-transferase theta 1 |
| HCAR3 | hydroxycarboxylic acid receptor 3 |
| HDAC7 | histone deacetylase 7 |
| HIST1H2AI | histone cluster 1, H2ai |
| HIST1H3B | histone cluster 1, H3b |
| HOXC8 | homeobox C8 |
| ICAM5 | intercellular adhesion molecule 5, telencephalin |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa |
| IPO8 | importin 8 |
| KCNA3 | potassium channel, voltage gated shaker related subfamily A, member 3 |
| MEP1B | meprin A, beta |
| METTL16 | methyltransferase like 16 |
| MFSD11 | major facilitator superfamily domain containing 11 |
| MRAS | muscle RAS oncogene homolog |
| MVP | major vault protein |
| MYOZ1 | myozenin 1 |
| MYOZ3 | myozenin 3 |
| NDUFAF7 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 7 |
| OLAH | oleoyl-ACP hydrolase |
| PDE6H | phosphodiesterase 6H, cGMP-specific, cone, gamma |
| PLD3 | phospholipase D family, member 3 |
| PLK2 | polo-like kinase 2 |
| PMP22 | peripheral myelin protein 22 |
| PORCN | porcupine homolog (Drosophila) |
| POU5F1B | POU class 5 homeobox 1B |
| PRSS53 | protease, serine, 53 |
| RAB33A | RAB33A, member RAS oncogene family |
| RCAN3 | RCAN family member 3 |
| RHBDF1 | rhomboid 5 homolog 1 (Drosophila) |
| RHOB | ras homolog family member B |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| RPL10L | ribosomal protein L10-like |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| SIRAL2 | SIR2 antiphage like 2 |
| SLC12A5 | solute carrier family 12 (potassium/chloride transporter), member 5 |
| SLC6A20 | solute carrier family 6 (proline IMINO transporter), member 20 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| TBL1Y | transducin (beta)-like 1, Y-linked |
| TCEB3B | transcription elongation factor B polypeptide 3B (elongin A2) |
| THBS3 | thrombospondin 3 |
| TMEM242 | transmembrane protein 242 |
| TPM3 | tropomyosin 3 |
| TRIP10 | thyroid hormone receptor interactor 10 |
| TRPS1 | trichorhinophalangeal syndrome I |
| TTC4 | tetratricopeptide repeat domain 4 |
| TUBA3C | tubulin, alpha 3c |
| UAP1L1 | UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 |
| ZBTB33 | zinc finger and BTB domain containing 33 |
| ZNF219 | zinc finger protein 219 |
| ZNF492 | zinc finger protein 492 |
| ZNF668 | zinc finger protein 668 |
| ZNF695 | zinc finger protein 695 |
| ZNF778 | zinc finger protein 778 |
