| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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194 genes differentially expressed following the butacaine-3469 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A4GALT | alpha 1,4-galactosyltransferase |
| ALDH4A1 | aldehyde dehydrogenase 4 family, member A1 |
| AMT | aminomethyltransferase |
| ANXA2P3 | annexin A2 pseudogene 3 |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
| ATP10D | ATPase, class V, type 10D |
| BCL2L11 | BCL2-like 11 (apoptosis facilitator) |
| BTRC | beta-transducin repeat containing E3 ubiquitin protein ligase |
| C19ORF66 | chromosome 19 open reading frame 66 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CACNA1H | calcium channel, voltage-dependent, T type, alpha 1H subunit |
| CD300C | CD300c molecule |
| CDC25C | cell division cycle 25C |
| CDC42EP2 | CDC42 effector protein (Rho GTPase binding) 2 |
| CDH8 | cadherin 8, type 2 |
| CFAP45 | cilia and flagella associated protein 45 |
| CHKB | choline kinase beta |
| COL5A1 | collagen, type V, alpha 1 |
| CR1 | complement component (3b/4b) receptor 1 (Knops blood group) |
| CUEDC1 | CUE domain containing 1 |
| DCAF15 | DDB1 and CUL4 associated factor 15 |
| DHX34 | DEAH (Asp-Glu-Ala-His) box polypeptide 34 |
| DIAPH1 | diaphanous-related formin 1 |
| DIAPH2 | diaphanous-related formin 2 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| EDN3 | endothelin 3 |
| EDRF1 | erythroid differentiation regulatory factor 1 |
| ERAP1 | endoplasmic reticulum aminopeptidase 1 |
| ERC2-IT1 | ERC2 intronic transcript 1 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 |
| FSCN1 | fascin actin-bundling protein 1 |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| GFI1 | growth factor independent 1 transcription repressor |
| GGA1 | golgi-associated, gamma adaptin ear containing, ARF binding protein 1 |
| GPR107 | G protein-coupled receptor 107 |
| HFE | hemochromatosis |
| HRH1 | histamine receptor H1 |
| IFI35 | interferon-induced protein 35 |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| IL17RA | interleukin 17 receptor A |
| IL1A | interleukin 1, alpha |
| IL5RA | interleukin 5 receptor, alpha |
| INSR | insulin receptor |
| IPO9 | importin 9 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| JAK2 | Janus kinase 2 |
| JRK | Jrk homolog (mouse) |
| KCNAB2 | potassium channel, voltage gated subfamily A regulatory beta subunit 2 |
| KCTD7 | potassium channel tetramerization domain containing 7 |
| KIAA0930 | KIAA0930 |
| LINC00339 | long intergenic non-protein coding RNA 339 |
| LTC4S | leukotriene C4 synthase |
| MAN2A2 | mannosidase, alpha, class 2A, member 2 |
| MAP4 | microtubule-associated protein 4 |
| MC1R | melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) |
| MEFV | Mediterranean fever |
| METTL7A | methyltransferase like 7A |
| MMP17 | matrix metallopeptidase 17 (membrane-inserted) |
| NCOA2 | nuclear receptor coactivator 2 |
| NOL10 | nucleolar protein 10 |
| PCDHA6 | protocadherin alpha 6 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) |
| PDE3B | phosphodiesterase 3B, cGMP-inhibited |
| PHF8 | PHD finger protein 8 |
| PIDD1 | p53-induced death domain protein 1 |
| PIGN | phosphatidylinositol glycan anchor biosynthesis, class N |
| PLSCR3 | phospholipid scramblase 3 |
| POFUT1 | protein O-fucosyltransferase 1 |
| PXN | paxillin |
| RAB2A | RAB2A, member RAS oncogene family |
| RANBP1 | RAN binding protein 1 |
| REEP2 | receptor accessory protein 2 |
| RER1 | retention in endoplasmic reticulum sorting receptor 1 |
| RNF19B | ring finger protein 19B |
| ROR2 | receptor tyrosine kinase-like orphan receptor 2 |
| RTEL1 | regulator of telomere elongation helicase 1 |
| SGSM3 | small G protein signaling modulator 3 |
| SIN3B | SIN3 transcription regulator family member B |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 |
| SOS2 | son of sevenless homolog 2 (Drosophila) |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 |
| STK17A | serine/threonine kinase 17a |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) |
| TAZ | tafazzin |
| TCP11L1 | t-complex 11, testis-specific-like 1 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TFEB | transcription factor EB |
| TMC6 | transmembrane channel-like 6 |
| TRAF2 | TNF receptor-associated factor 2 |
| TRIO | trio Rho guanine nucleotide exchange factor |
| TRPV6 | transient receptor potential cation channel, subfamily V, member 6 |
| UBAP2L | ubiquitin associated protein 2-like |
| URB2 | URB2 ribosome biogenesis 2 homolog (S. cerevisiae) |
| VAMP1 | vesicle-associated membrane protein 1 (synaptobrevin 1) |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZNF609 | zinc finger protein 609 |
| Symbol | Name |
|---|---|
| ABCA12 | ATP-binding cassette, sub-family A (ABC1), member 12 |
| ALKBH4 | alkB, alkylation repair homolog 4 (E. coli) |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| APBB3 | amyloid beta (A4) precursor protein-binding, family B, member 3 |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
| BGLAP | bone gamma-carboxyglutamate (gla) protein |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| C1ORF56 | chromosome 1 open reading frame 56 |
| C2ORF54 | chromosome 2 open reading frame 54 |
| CCDC25 | coiled-coil domain containing 25 |
| CCNO | cyclin O |
| CDKL3 | cyclin-dependent kinase-like 3 |
| CENPO | centromere protein O |
| CFD | complement factor D (adipsin) |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 |
| CIR1 | corepressor interacting with RBPJ, 1 |
| CLSPN | claspin |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| CORO2A | coronin, actin binding protein, 2A |
| CORT | cortistatin |
| CRLF1 | cytokine receptor-like factor 1 |
| CTBS | chitobiase, di-N-acetyl- |
| DMC1 | DNA meiotic recombinase 1 |
| DSCAM | Down syndrome cell adhesion molecule |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 |
| FAM131A | family with sequence similarity 131, member A |
| FAM53B | family with sequence similarity 53, member B |
| FKBP5 | FK506 binding protein 5 |
| FOSL1 | FOS-like antigen 1 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) |
| GFOD1 | glucose-fructose oxidoreductase domain containing 1 |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GPN2 | GPN-loop GTPase 2 |
| GPR143 | G protein-coupled receptor 143 |
| GTF2H3 | general transcription factor IIH, polypeptide 3, 34kDa |
| HIST1H2AM | histone cluster 1, H2am |
| HIST1H2BO | histone cluster 1, H2bo |
| HIST1H3B | histone cluster 1, H3b |
| HLA-J | major histocompatibility complex, class I, J (pseudogene) |
| HSD17B1 | hydroxysteroid (17-beta) dehydrogenase 1 |
| INCENP | inner centromere protein antigens 135/155kDa |
| IPO8 | importin 8 |
| KCNK12 | potassium channel, two pore domain subfamily K, member 12 |
| KIAA0319L | KIAA0319-like |
| LOC257152 | uncharacterized LOC257152 |
| LOC390998 | ribosomal protein L10 pseudogene |
| LPAR4 | lysophosphatidic acid receptor 4 |
| LRRC23 | leucine rich repeat containing 23 |
| LRRC61 | leucine rich repeat containing 61 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MAP4K2 | mitogen-activated protein kinase kinase kinase kinase 2 |
| MAP9 | microtubule-associated protein 9 |
| MAPK8 | mitogen-activated protein kinase 8 |
| MCOLN1 | mucolipin 1 |
| NTHL1 | nth endonuclease III-like 1 (E. coli) |
| NUBP2 | nucleotide binding protein 2 |
| NUS1P3 | nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3 |
| NXPH4 | neurexophilin 4 |
| P2RY2 | purinergic receptor P2Y, G-protein coupled, 2 |
| PCDHB3 | protocadherin beta 3 |
| PDK1 | pyruvate dehydrogenase kinase, isozyme 1 |
| PDLIM2 | PDZ and LIM domain 2 (mystique) |
| PGS1 | phosphatidylglycerophosphate synthase 1 |
| PIN1 | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 |
| PLD3 | phospholipase D family, member 3 |
| PSTPIP2 | proline-serine-threonine phosphatase interacting protein 2 |
| RAB4B | RAB4B, member RAS oncogene family |
| RNF170 | ring finger protein 170 |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SGCG | sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) |
| SLC12A8 | solute carrier family 12, member 8 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 |
| SREK1IP1 | SREK1-interacting protein 1 |
| STARD5 | StAR-related lipid transfer (START) domain containing 5 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TBC1D17 | TBC1 domain family, member 17 |
| THBS3 | thrombospondin 3 |
| TMC5 | transmembrane channel-like 5 |
| TMC7 | transmembrane channel-like 7 |
| TMEM53 | transmembrane protein 53 |
| TPST1 | tyrosylprotein sulfotransferase 1 |
| UBQLN4 | ubiquilin 4 |
| VAX2 | ventral anterior homeobox 2 |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| XYLT2 | xylosyltransferase II |
| ZBTB48 | zinc finger and BTB domain containing 48 |
| ZDHHC11 | zinc finger, DHHC-type containing 11 |
| ZNF408 | zinc finger protein 408 |
| ZNF552 | zinc finger protein 552 |
| ZNF586 | zinc finger protein 586 |
| ZNF652 | zinc finger protein 652 |
| ZNF669 | zinc finger protein 669 |
| ZNF816 | zinc finger protein 816 |