butacaine-3469 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the butacaine-3469 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
AMT aminomethyltransferase
ANXA2P3 annexin A2 pseudogene 3
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ATP10D ATPase, class V, type 10D
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
C19ORF66 chromosome 19 open reading frame 66
C7ORF43 chromosome 7 open reading frame 43
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CD300C CD300c molecule
CDC25C cell division cycle 25C
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2
CDH8 cadherin 8, type 2
CFAP45 cilia and flagella associated protein 45
CHKB choline kinase beta
COL5A1 collagen, type V, alpha 1
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CUEDC1 CUE domain containing 1
DCAF15 DDB1 and CUL4 associated factor 15
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
DIAPH1 diaphanous-related formin 1
DIAPH2 diaphanous-related formin 2
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
EDN3 endothelin 3
EDRF1 erythroid differentiation regulatory factor 1
ERAP1 endoplasmic reticulum aminopeptidase 1
ERC2-IT1 ERC2 intronic transcript 1
ERN1 endoplasmic reticulum to nucleus signaling 1
FSCN1 fascin actin-bundling protein 1
FSTL3 follistatin-like 3 (secreted glycoprotein)
GFI1 growth factor independent 1 transcription repressor
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1
GPR107 G protein-coupled receptor 107
HFE hemochromatosis
HRH1 histamine receptor H1
IFI35 interferon-induced protein 35
IGFBP5 insulin-like growth factor binding protein 5
IL17RA interleukin 17 receptor A
IL1A interleukin 1, alpha
IL5RA interleukin 5 receptor, alpha
INSR insulin receptor
IPO9 importin 9
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
JAK2 Janus kinase 2
JRK Jrk homolog (mouse)
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2
KCTD7 potassium channel tetramerization domain containing 7
KIAA0930 KIAA0930
LINC00339 long intergenic non-protein coding RNA 339
LTC4S leukotriene C4 synthase
MAN2A2 mannosidase, alpha, class 2A, member 2
MAP4 microtubule-associated protein 4
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MEFV Mediterranean fever
METTL7A methyltransferase like 7A
MMP17 matrix metallopeptidase 17 (membrane-inserted)
NCOA2 nuclear receptor coactivator 2
NOL10 nucleolar protein 10
PCDHA6 protocadherin alpha 6
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PDE3B phosphodiesterase 3B, cGMP-inhibited
PHF8 PHD finger protein 8
PIDD1 p53-induced death domain protein 1
PIGN phosphatidylinositol glycan anchor biosynthesis, class N
PLSCR3 phospholipid scramblase 3
POFUT1 protein O-fucosyltransferase 1
PXN paxillin
RAB2A RAB2A, member RAS oncogene family
RANBP1 RAN binding protein 1
REEP2 receptor accessory protein 2
RER1 retention in endoplasmic reticulum sorting receptor 1
RNF19B ring finger protein 19B
ROR2 receptor tyrosine kinase-like orphan receptor 2
RTEL1 regulator of telomere elongation helicase 1
SGSM3 small G protein signaling modulator 3
SIN3B SIN3 transcription regulator family member B
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SOS2 son of sevenless homolog 2 (Drosophila)
SPTAN1 spectrin, alpha, non-erythrocytic 1
STK17A serine/threonine kinase 17a
SUPT6H suppressor of Ty 6 homolog (S. cerevisiae)
TAZ tafazzin
TCP11L1 t-complex 11, testis-specific-like 1
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TFEB transcription factor EB
TMC6 transmembrane channel-like 6
TRAF2 TNF receptor-associated factor 2
TRIO trio Rho guanine nucleotide exchange factor
TRPV6 transient receptor potential cation channel, subfamily V, member 6
UBAP2L ubiquitin associated protein 2-like
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)
ZBTB22 zinc finger and BTB domain containing 22
ZNF609 zinc finger protein 609

decreased expression

Symbol Name
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ANKFY1 ankyrin repeat and FYVE domain containing 1
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
BGLAP bone gamma-carboxyglutamate (gla) protein
BTF3P12 basic transcription factor 3 pseudogene 12
C1ORF56 chromosome 1 open reading frame 56
C2ORF54 chromosome 2 open reading frame 54
CCDC25 coiled-coil domain containing 25
CCNO cyclin O
CDKL3 cyclin-dependent kinase-like 3
CENPO centromere protein O
CFD complement factor D (adipsin)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CIR1 corepressor interacting with RBPJ, 1
CLSPN claspin
CNGB3 cyclic nucleotide gated channel beta 3
CORO2A coronin, actin binding protein, 2A
CORT cortistatin
CRLF1 cytokine receptor-like factor 1
CTBS chitobiase, di-N-acetyl-
DMC1 DNA meiotic recombinase 1
DSCAM Down syndrome cell adhesion molecule
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EPB41L5 erythrocyte membrane protein band 4.1 like 5
FAM131A family with sequence similarity 131, member A
FAM53B family with sequence similarity 53, member B
FKBP5 FK506 binding protein 5
FOSL1 FOS-like antigen 1
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GFOD1 glucose-fructose oxidoreductase domain containing 1
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GPN2 GPN-loop GTPase 2
GPR143 G protein-coupled receptor 143
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
HIST1H2AM histone cluster 1, H2am
HIST1H2BO histone cluster 1, H2bo
HIST1H3B histone cluster 1, H3b
HLA-J major histocompatibility complex, class I, J (pseudogene)
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
INCENP inner centromere protein antigens 135/155kDa
IPO8 importin 8
KCNK12 potassium channel, two pore domain subfamily K, member 12
KIAA0319L KIAA0319-like
LOC257152 uncharacterized LOC257152
LOC390998 ribosomal protein L10 pseudogene
LPAR4 lysophosphatidic acid receptor 4
LRRC23 leucine rich repeat containing 23
LRRC61 leucine rich repeat containing 61
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MAP9 microtubule-associated protein 9
MAPK8 mitogen-activated protein kinase 8
MCOLN1 mucolipin 1
NTHL1 nth endonuclease III-like 1 (E. coli)
NUBP2 nucleotide binding protein 2
NUS1P3 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3
NXPH4 neurexophilin 4
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
PCDHB3 protocadherin beta 3
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PDLIM2 PDZ and LIM domain 2 (mystique)
PGS1 phosphatidylglycerophosphate synthase 1
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PLD3 phospholipase D family, member 3
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2
RAB4B RAB4B, member RAS oncogene family
RNF170 ring finger protein 170
SCN1B sodium channel, voltage gated, type I beta subunit
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
SLC12A8 solute carrier family 12, member 8
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SREK1IP1 SREK1-interacting protein 1
STARD5 StAR-related lipid transfer (START) domain containing 5
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TBC1D17 TBC1 domain family, member 17
THBS3 thrombospondin 3
TMC5 transmembrane channel-like 5
TMC7 transmembrane channel-like 7
TMEM53 transmembrane protein 53
TPST1 tyrosylprotein sulfotransferase 1
UBQLN4 ubiquilin 4
VAX2 ventral anterior homeobox 2
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
XYLT2 xylosyltransferase II
ZBTB48 zinc finger and BTB domain containing 48
ZDHHC11 zinc finger, DHHC-type containing 11
ZNF408 zinc finger protein 408
ZNF552 zinc finger protein 552
ZNF586 zinc finger protein 586
ZNF652 zinc finger protein 652
ZNF669 zinc finger protein 669
ZNF816 zinc finger protein 816