butacaine-5748 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the butacaine-5748 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ACSBG2 acyl-CoA synthetase bubblegum family member 2
ACSS3 acyl-CoA synthetase short-chain family member 3
ADAM19 ADAM metallopeptidase domain 19
ADCK4 aarF domain containing kinase 4
AHNAK AHNAK nucleoprotein
AKAP6 A kinase (PRKA) anchor protein 6
ATPAF2 ATP synthase mitochondrial F1 complex assembly factor 2
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1
CALHM2 calcium homeostasis modulator 2
CCDC57 coiled-coil domain containing 57
CD200 CD200 molecule
CD34 CD34 molecule
CD48 CD48 molecule
CD53 CD53 molecule
CDKL3 cyclin-dependent kinase-like 3
CEACAM21 carcinoembryonic antigen-related cell adhesion molecule 21
CLEC11A C-type lectin domain family 11, member A
COL4A6 collagen, type IV, alpha 6
COL9A3 collagen, type IX, alpha 3
COMT catechol-O-methyltransferase
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CTAGE1 cutaneous T-cell lymphoma-associated antigen 1
CTSZ cathepsin Z
CUX2 cut-like homeobox 2
CXCR4 chemokine (C-X-C motif) receptor 4
DENND3 DENN/MADD domain containing 3
DLC1 DLC1 Rho GTPase activating protein
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DSCC1 DNA replication and sister chromatid cohesion 1
DSG3 desmoglein 3
DSTYK dual serine/threonine and tyrosine protein kinase
DVL2 dishevelled segment polarity protein 2
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GHRHR growth hormone releasing hormone receptor
GPR1 G protein-coupled receptor 1
GREB1L growth regulation by estrogen in breast cancer-like
GSTM5 glutathione S-transferase mu 5
HBS1L HBS1-like translational GTPase
HEMK1 HemK methyltransferase family member 1
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HLA-DOA major histocompatibility complex, class II, DO alpha
HOMER3 homer scaffolding protein 3
IGFBP7 insulin-like growth factor binding protein 7
KHSRP KH-type splicing regulatory protein
KLF1 Kruppel-like factor 1 (erythroid)
LAMB4 laminin, beta 4
LMO1 LIM domain only 1 (rhombotin 1)
LMTK1 lemur tail kinase 1
MAGEA12 melanoma antigen family A12
MAPK7 mitogen-activated protein kinase 7
MC2R melanocortin 2 receptor (adrenocorticotropic hormone)
MEFV Mediterranean fever
MEGF8 multiple EGF-like-domains 8
MRPL41 mitochondrial ribosomal protein L41
N4BP2L1 NEDD4 binding protein 2-like 1
NAGLU N-acetylglucosaminidase, alpha
NDNF neuron-derived neurotrophic factor
ORC5 origin recognition complex, subunit 5
PACS1 phosphofurin acidic cluster sorting protein 1
PAWR PRKC, apoptosis, WT1, regulator
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCDHA9 protocadherin alpha 9
PDCD2 programmed cell death 2
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PER2 period circadian clock 2
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PLXNC1 plexin C1
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PRKCB protein kinase C, beta
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa
PTN pleiotrophin
RAB6A RAB6A, member RAS oncogene family
RABEP2 rabaptin, RAB GTPase binding effector protein 2
RASA3 RAS p21 protein activator 3
RASAL2 RAS protein activator like 2
RGS5 regulator of G-protein signaling 5
RNF43 ring finger protein 43
RXRB retinoid X receptor, beta
SH3BP2 SH3-domain binding protein 2
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SMAD7 SMAD family member 7
SMC1A structural maintenance of chromosomes 1A
SOSTDC1 sclerostin domain containing 1
SRCAP Snf2-related CREBBP activator protein
SRSF7 serine/arginine-rich splicing factor 7
STK11 serine/threonine kinase 11
TAAR2 trace amine associated receptor 2
TADA3 transcriptional adaptor 3
TAGLN3 transgelin 3
TPM1 tropomyosin 1 (alpha)
TRA T cell receptor alpha locus
TSSK2 testis-specific serine kinase 2
UPK3B uroplakin 3B
USB1 U6 snRNA biogenesis 1
VAMP5 vesicle-associated membrane protein 5
ZBED4 zinc finger, BED-type containing 4
ZNF384 zinc finger protein 384

decreased expression

Symbol Name
ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8
ACTG2 actin, gamma 2, smooth muscle, enteric
ADAP2 ArfGAP with dual PH domains 2
ADTRP androgen-dependent TFPI-regulating protein
AFAP1 actin filament associated protein 1
ANP32A-IT1 ANP32A intronic transcript 1
AP1B1 adaptor-related protein complex 1, beta 1 subunit
ARID4A AT rich interactive domain 4A (RBP1-like)
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
BAHCC1 BAH domain and coiled-coil containing 1
C22ORF29 chromosome 22 open reading frame 29
CAMTA2 calmodulin binding transcription activator 2
CCDC25 coiled-coil domain containing 25
CDK6 cyclin-dependent kinase 6
CGREF1 cell growth regulator with EF-hand domain 1
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal)
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CRYBA2 crystallin, beta A2
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CTSF cathepsin F
CTSK cathepsin K
DDN dendrin
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
EAF2 ELL associated factor 2
ELOVL4 ELOVL fatty acid elongase 4
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
ERN2 endoplasmic reticulum to nucleus signaling 2
FGL1 fibrinogen-like 1
FMO4 flavin containing monooxygenase 4
FOXN2 forkhead box N2
FSD1 fibronectin type III and SPRY domain containing 1
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GPR3 G protein-coupled receptor 3
GPRASP1 G protein-coupled receptor associated sorting protein 1
GRAMD1C GRAM domain containing 1C
GRB7 growth factor receptor-bound protein 7
HIST1H2AI histone cluster 1, H2ai
HIST1H2BI histone cluster 1, H2bi
HIST1H2BM histone cluster 1, H2bm
HSF2BP heat shock transcription factor 2 binding protein
IFI6 interferon, alpha-inducible protein 6
IFNA14 interferon, alpha 14
IL17RB interleukin 17 receptor B
IPO8 importin 8
ITK IL2-inducible T-cell kinase
KDM7A lysine (K)-specific demethylase 7A
KLHL3 kelch-like family member 3
KLK5 kallikrein-related peptidase 5
KRT9 keratin 9, type I
LIFR leukemia inhibitory factor receptor alpha
LMBR1L limb development membrane protein 1-like
LOC257152 uncharacterized LOC257152
LRP3 low density lipoprotein receptor-related protein 3
MILR1 mast cell immunoglobulin-like receptor 1
MTA2 metastasis associated 1 family, member 2
MVD mevalonate (diphospho) decarboxylase
NACA2 nascent polypeptide-associated complex alpha subunit 2
NID2 nidogen 2 (osteonidogen)
NOL12 nucleolar protein 12
NPFFR1 neuropeptide FF receptor 1
NPM3 nucleophosmin/nucleoplasmin 3
NRTN neurturin
NTSR1 neurotensin receptor 1 (high affinity)
NYNRIN NYN domain and retroviral integrase containing
PECR peroxisomal trans-2-enoyl-CoA reductase
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PIDD1 p53-induced death domain protein 1
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PRAMEF11 PRAME family member 11
PWAR5 Prader Willi/Angelman region RNA 5
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RANBP17 RAN binding protein 17
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RIN1 Ras and Rab interactor 1
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
SEC14L2 SEC14-like 2 (S. cerevisiae)
SH3BGR SH3 domain binding glutamate-rich protein
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
STEAP4 STEAP family member 4
SUGCT succinyl-CoA:glutarate-CoA transferase
TCTN2 tectonic family member 2
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TM6SF1 transmembrane 6 superfamily member 1
TRIM25 tripartite motif containing 25
TUBA3C tubulin, alpha 3c
VWA1 von Willebrand factor A domain containing 1
WDR78 WD repeat domain 78
YY2 YY2 transcription factor
ZBTB22 zinc finger and BTB domain containing 22
ZFHX2 zinc finger homeobox 2
ZNF10 zinc finger protein 10
ZNF250 zinc finger protein 250
ZNF358 zinc finger protein 358
ZNF747 zinc finger protein 747
ZNF862 zinc finger protein 862