| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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200 genes differentially expressed following the butacaine-5748 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 |
| ACSBG2 | acyl-CoA synthetase bubblegum family member 2 |
| ACSS3 | acyl-CoA synthetase short-chain family member 3 |
| ADAM19 | ADAM metallopeptidase domain 19 |
| ADCK4 | aarF domain containing kinase 4 |
| AHNAK | AHNAK nucleoprotein |
| AKAP6 | A kinase (PRKA) anchor protein 6 |
| ATPAF2 | ATP synthase mitochondrial F1 complex assembly factor 2 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 |
| CALHM2 | calcium homeostasis modulator 2 |
| CCDC57 | coiled-coil domain containing 57 |
| CD200 | CD200 molecule |
| CD34 | CD34 molecule |
| CD48 | CD48 molecule |
| CD53 | CD53 molecule |
| CDKL3 | cyclin-dependent kinase-like 3 |
| CEACAM21 | carcinoembryonic antigen-related cell adhesion molecule 21 |
| CLEC11A | C-type lectin domain family 11, member A |
| COL4A6 | collagen, type IV, alpha 6 |
| COL9A3 | collagen, type IX, alpha 3 |
| COMT | catechol-O-methyltransferase |
| CR1 | complement component (3b/4b) receptor 1 (Knops blood group) |
| CTAGE1 | cutaneous T-cell lymphoma-associated antigen 1 |
| CTSZ | cathepsin Z |
| CUX2 | cut-like homeobox 2 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 |
| DENND3 | DENN/MADD domain containing 3 |
| DLC1 | DLC1 Rho GTPase activating protein |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
| DSCC1 | DNA replication and sister chromatid cohesion 1 |
| DSG3 | desmoglein 3 |
| DSTYK | dual serine/threonine and tyrosine protein kinase |
| DVL2 | dishevelled segment polarity protein 2 |
| GABBR1 | gamma-aminobutyric acid (GABA) B receptor, 1 |
| GHRHR | growth hormone releasing hormone receptor |
| GPR1 | G protein-coupled receptor 1 |
| GREB1L | growth regulation by estrogen in breast cancer-like |
| GSTM5 | glutathione S-transferase mu 5 |
| HBS1L | HBS1-like translational GTPase |
| HEMK1 | HemK methyltransferase family member 1 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HLA-DOA | major histocompatibility complex, class II, DO alpha |
| HOMER3 | homer scaffolding protein 3 |
| IGFBP7 | insulin-like growth factor binding protein 7 |
| KHSRP | KH-type splicing regulatory protein |
| KLF1 | Kruppel-like factor 1 (erythroid) |
| LAMB4 | laminin, beta 4 |
| LMO1 | LIM domain only 1 (rhombotin 1) |
| LMTK1 | lemur tail kinase 1 |
| MAGEA12 | melanoma antigen family A12 |
| MAPK7 | mitogen-activated protein kinase 7 |
| MC2R | melanocortin 2 receptor (adrenocorticotropic hormone) |
| MEFV | Mediterranean fever |
| MEGF8 | multiple EGF-like-domains 8 |
| MRPL41 | mitochondrial ribosomal protein L41 |
| N4BP2L1 | NEDD4 binding protein 2-like 1 |
| NAGLU | N-acetylglucosaminidase, alpha |
| NDNF | neuron-derived neurotrophic factor |
| ORC5 | origin recognition complex, subunit 5 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PAWR | PRKC, apoptosis, WT1, regulator |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PCDHA9 | protocadherin alpha 9 |
| PDCD2 | programmed cell death 2 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 |
| PER2 | period circadian clock 2 |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 |
| PLXNC1 | plexin C1 |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PRKCB | protein kinase C, beta |
| PTGER1 | prostaglandin E receptor 1 (subtype EP1), 42kDa |
| PTN | pleiotrophin |
| RAB6A | RAB6A, member RAS oncogene family |
| RABEP2 | rabaptin, RAB GTPase binding effector protein 2 |
| RASA3 | RAS p21 protein activator 3 |
| RASAL2 | RAS protein activator like 2 |
| RGS5 | regulator of G-protein signaling 5 |
| RNF43 | ring finger protein 43 |
| RXRB | retinoid X receptor, beta |
| SH3BP2 | SH3-domain binding protein 2 |
| SLC25A21 | solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SMAD7 | SMAD family member 7 |
| SMC1A | structural maintenance of chromosomes 1A |
| SOSTDC1 | sclerostin domain containing 1 |
| SRCAP | Snf2-related CREBBP activator protein |
| SRSF7 | serine/arginine-rich splicing factor 7 |
| STK11 | serine/threonine kinase 11 |
| TAAR2 | trace amine associated receptor 2 |
| TADA3 | transcriptional adaptor 3 |
| TAGLN3 | transgelin 3 |
| TPM1 | tropomyosin 1 (alpha) |
| TRA | T cell receptor alpha locus |
| TSSK2 | testis-specific serine kinase 2 |
| UPK3B | uroplakin 3B |
| USB1 | U6 snRNA biogenesis 1 |
| VAMP5 | vesicle-associated membrane protein 5 |
| ZBED4 | zinc finger, BED-type containing 4 |
| ZNF384 | zinc finger protein 384 |
| Symbol | Name |
|---|---|
| ABCB8 | ATP-binding cassette, sub-family B (MDR/TAP), member 8 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| ADAP2 | ArfGAP with dual PH domains 2 |
| ADTRP | androgen-dependent TFPI-regulating protein |
| AFAP1 | actin filament associated protein 1 |
| ANP32A-IT1 | ANP32A intronic transcript 1 |
| AP1B1 | adaptor-related protein complex 1, beta 1 subunit |
| ARID4A | AT rich interactive domain 4A (RBP1-like) |
| B4GALNT1 | beta-1,4-N-acetyl-galactosaminyl transferase 1 |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| C22ORF29 | chromosome 22 open reading frame 29 |
| CAMTA2 | calmodulin binding transcription activator 2 |
| CCDC25 | coiled-coil domain containing 25 |
| CDK6 | cyclin-dependent kinase 6 |
| CGREF1 | cell growth regulator with EF-hand domain 1 |
| CHRNA10 | cholinergic receptor, nicotinic, alpha 10 (neuronal) |
| CHST8 | carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 |
| CNKSR1 | connector enhancer of kinase suppressor of Ras 1 |
| CRYBA2 | crystallin, beta A2 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 |
| CTSF | cathepsin F |
| CTSK | cathepsin K |
| DDN | dendrin |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| DHX35 | DEAH (Asp-Glu-Ala-His) box polypeptide 35 |
| EAF2 | ELL associated factor 2 |
| ELOVL4 | ELOVL fatty acid elongase 4 |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FGL1 | fibrinogen-like 1 |
| FMO4 | flavin containing monooxygenase 4 |
| FOXN2 | forkhead box N2 |
| FSD1 | fibronectin type III and SPRY domain containing 1 |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GNA14 | guanine nucleotide binding protein (G protein), alpha 14 |
| GNG3 | guanine nucleotide binding protein (G protein), gamma 3 |
| GPR3 | G protein-coupled receptor 3 |
| GPRASP1 | G protein-coupled receptor associated sorting protein 1 |
| GRAMD1C | GRAM domain containing 1C |
| GRB7 | growth factor receptor-bound protein 7 |
| HIST1H2AI | histone cluster 1, H2ai |
| HIST1H2BI | histone cluster 1, H2bi |
| HIST1H2BM | histone cluster 1, H2bm |
| HSF2BP | heat shock transcription factor 2 binding protein |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFNA14 | interferon, alpha 14 |
| IL17RB | interleukin 17 receptor B |
| IPO8 | importin 8 |
| ITK | IL2-inducible T-cell kinase |
| KDM7A | lysine (K)-specific demethylase 7A |
| KLHL3 | kelch-like family member 3 |
| KLK5 | kallikrein-related peptidase 5 |
| KRT9 | keratin 9, type I |
| LIFR | leukemia inhibitory factor receptor alpha |
| LMBR1L | limb development membrane protein 1-like |
| LOC257152 | uncharacterized LOC257152 |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| MILR1 | mast cell immunoglobulin-like receptor 1 |
| MTA2 | metastasis associated 1 family, member 2 |
| MVD | mevalonate (diphospho) decarboxylase |
| NACA2 | nascent polypeptide-associated complex alpha subunit 2 |
| NID2 | nidogen 2 (osteonidogen) |
| NOL12 | nucleolar protein 12 |
| NPFFR1 | neuropeptide FF receptor 1 |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NRTN | neurturin |
| NTSR1 | neurotensin receptor 1 (high affinity) |
| NYNRIN | NYN domain and retroviral integrase containing |
| PECR | peroxisomal trans-2-enoyl-CoA reductase |
| PGGT1B | protein geranylgeranyltransferase type I, beta subunit |
| PIDD1 | p53-induced death domain protein 1 |
| PIGZ | phosphatidylinositol glycan anchor biosynthesis, class Z |
| PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 |
| PRAMEF11 | PRAME family member 11 |
| PWAR5 | Prader Willi/Angelman region RNA 5 |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RANBP17 | RAN binding protein 17 |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 |
| RIN1 | Ras and Rab interactor 1 |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase |
| SEC14L2 | SEC14-like 2 (S. cerevisiae) |
| SH3BGR | SH3 domain binding glutamate-rich protein |
| SMPDL3B | sphingomyelin phosphodiesterase, acid-like 3B |
| STEAP4 | STEAP family member 4 |
| SUGCT | succinyl-CoA:glutarate-CoA transferase |
| TCTN2 | tectonic family member 2 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TM6SF1 | transmembrane 6 superfamily member 1 |
| TRIM25 | tripartite motif containing 25 |
| TUBA3C | tubulin, alpha 3c |
| VWA1 | von Willebrand factor A domain containing 1 |
| WDR78 | WD repeat domain 78 |
| YY2 | YY2 transcription factor |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZFHX2 | zinc finger homeobox 2 |
| ZNF10 | zinc finger protein 10 |
| ZNF250 | zinc finger protein 250 |
| ZNF358 | zinc finger protein 358 |
| ZNF747 | zinc finger protein 747 |
| ZNF862 | zinc finger protein 862 |