| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the butacaine-6225 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACSM5 | acyl-CoA synthetase medium-chain family member 5 |
| ADAM23 | ADAM metallopeptidase domain 23 |
| ADGRE5 | adhesion G protein-coupled receptor E5 |
| AGPAT2 | 1-acylglycerol-3-phosphate O-acyltransferase 2 |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| ALOX12P2 | arachidonate 12-lipoxygenase pseudogene 2 |
| ASTN2 | astrotactin 2 |
| ATAD5 | ATPase family, AAA domain containing 5 |
| ATP7A | ATPase, Cu++ transporting, alpha polypeptide |
| BCL11A | B-cell CLL/lymphoma 11A (zinc finger protein) |
| C21ORF2 | chromosome 21 open reading frame 2 |
| CCRL2 | chemokine (C-C motif) receptor-like 2 |
| CDC25A | cell division cycle 25A |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 |
| CIR1 | corepressor interacting with RBPJ, 1 |
| CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
| CREBZF | CREB/ATF bZIP transcription factor |
| CYP2D6 | cytochrome P450, family 2, subfamily D, polypeptide 6 |
| CYP2R1 | cytochrome P450, family 2, subfamily R, polypeptide 1 |
| DGCR8 | DGCR8 microprocessor complex subunit |
| DIO2 | deiodinase, iodothyronine, type II |
| DSCAM | Down syndrome cell adhesion molecule |
| EFEMP2 | EGF containing fibulin-like extracellular matrix protein 2 |
| EPHA2 | EPH receptor A2 |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| GATA4 | GATA binding protein 4 |
| GMPR | guanosine monophosphate reductase |
| GPR153 | G protein-coupled receptor 153 |
| GPR176 | G protein-coupled receptor 176 |
| GSTA3 | glutathione S-transferase alpha 3 |
| HIST1H2AJ | histone cluster 1, H2aj |
| HNF1B | HNF1 homeobox B |
| HOMER3 | homer scaffolding protein 3 |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein |
| IFNA14 | interferon, alpha 14 |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 |
| KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) |
| KRT19P2 | keratin 19 pseudogene 2 |
| LAT2 | linker for activation of T cells family, member 2 |
| LILRB2 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 |
| LRRC41 | leucine rich repeat containing 41 |
| LUZP1 | leucine zipper protein 1 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B |
| MAGOH2P | mago-nashi homolog 2, pseudogene |
| MAL | mal, T-cell differentiation protein |
| MED14 | mediator complex subunit 14 |
| MICALL1 | MICAL-like 1 |
| MINK1 | misshapen-like kinase 1 |
| MPPE1 | metallophosphoesterase 1 |
| MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) |
| NKAIN1 | Na+/K+ transporting ATPase interacting 1 |
| NPTX1 | neuronal pentraxin I |
| NRGN | neurogranin (protein kinase C substrate, RC3) |
| OGFR | opioid growth factor receptor |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PGP | phosphoglycolate phosphatase |
| PHC3 | polyhomeotic homolog 3 (Drosophila) |
| PLCH1 | phospholipase C, eta 1 |
| POLL | polymerase (DNA directed), lambda |
| PPIA | peptidylprolyl isomerase A (cyclophilin A) |
| PRDX2 | peroxiredoxin 2 |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) |
| PYCRL | pyrroline-5-carboxylate reductase-like |
| RAB11FIP3 | RAB11 family interacting protein 3 (class II) |
| RARG | retinoic acid receptor, gamma |
| RGS10 | regulator of G-protein signaling 10 |
| RNASEL | ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 |
| RPS3A | ribosomal protein S3A |
| RUFY3 | RUN and FYVE domain containing 3 |
| SCG2 | secretogranin II |
| SERHL2 | serine hydrolase-like 2 |
| SLC19A1 | solute carrier family 19 (folate transporter), member 1 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 |
| SP100 | SP100 nuclear antigen |
| SPAG8 | sperm associated antigen 8 |
| ST20 | suppressor of tumorigenicity 20 |
| STYK1 | serine/threonine/tyrosine kinase 1 |
| SUGP1 | SURP and G patch domain containing 1 |
| SUPT7L | suppressor of Ty 7 (S. cerevisiae)-like |
| SYNGR1 | synaptogyrin 1 |
| TAP2 | transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) |
| TICAM1 | toll-like receptor adaptor molecule 1 |
| TMEM63A | transmembrane protein 63A |
| TUBGCP5 | tubulin, gamma complex associated protein 5 |
| UBE3A | ubiquitin protein ligase E3A |
| UBXN1 | UBX domain protein 1 |
| ULBP2 | UL16 binding protein 2 |
| VARS | valyl-tRNA synthetase |
| VIPR2 | vasoactive intestinal peptide receptor 2 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) |
| WDR1 | WD repeat domain 1 |
| WIPI2 | WD repeat domain, phosphoinositide interacting 2 |
| ZBED4 | zinc finger, BED-type containing 4 |
| ZER1 | zyg-11 related, cell cycle regulator |
| ZNF224 | zinc finger protein 224 |
| ZNF446 | zinc finger protein 446 |
| ZSCAN32 | zinc finger and SCAN domain containing 32 |
| Symbol | Name |
|---|---|
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 |
| AES | amino-terminal enhancer of split |
| AKR1C3 | aldo-keto reductase family 1, member C3 |
| AKTIP | AKT interacting protein |
| ATG2B | autophagy related 2B |
| B3GNT2 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| C10ORF88 | chromosome 10 open reading frame 88 |
| C11ORF95 | chromosome 11 open reading frame 95 |
| C12ORF4 | chromosome 12 open reading frame 4 |
| C22ORF29 | chromosome 22 open reading frame 29 |
| C4ORF29 | chromosome 4 open reading frame 29 |
| CAMTA2 | calmodulin binding transcription activator 2 |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase |
| CBX4 | chromobox homolog 4 |
| CBX7 | chromobox homolog 7 |
| CCDC85C | coiled-coil domain containing 85C |
| CCNJ | cyclin J |
| CFD | complement factor D (adipsin) |
| CLSTN1 | calsyntenin 1 |
| COPS7B | COP9 signalosome subunit 7B |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DEAF1 | DEAF1 transcription factor |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| DOCK1 | dedicator of cytokinesis 1 |
| EAF2 | ELL associated factor 2 |
| EIF5A2 | eukaryotic translation initiation factor 5A2 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 |
| EXOC2 | exocyst complex component 2 |
| FAM53B | family with sequence similarity 53, member B |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FPGS | folylpolyglutamate synthase |
| GLI3 | GLI family zinc finger 3 |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| GPATCH2 | G patch domain containing 2 |
| HIRIP3 | HIRA interacting protein 3 |
| HIST1H2AM | histone cluster 1, H2am |
| HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 |
| IFT81 | intraflagellar transport 81 |
| JUNB | jun B proto-oncogene |
| KDM5C | lysine (K)-specific demethylase 5C |
| KIAA0894 | KIAA0894 protein |
| KIF3B | kinesin family member 3B |
| KIFC1 | kinesin family member C1 |
| LEMD3 | LEM domain containing 3 |
| LMNB1 | lamin B1 |
| LRP5L | low density lipoprotein receptor-related protein 5-like |
| MAPK12 | mitogen-activated protein kinase 12 |
| MED15 | mediator complex subunit 15 |
| MFSD12 | major facilitator superfamily domain containing 12 |
| MNS1 | meiosis-specific nuclear structural 1 |
| MOCS3 | molybdenum cofactor synthesis 3 |
| MRPL2 | mitochondrial ribosomal protein L2 |
| MXI1 | MAX interactor 1, dimerization protein |
| MYBBP1A | MYB binding protein (P160) 1a |
| NCAM2 | neural cell adhesion molecule 2 |
| OCEL1 | occludin/ELL domain containing 1 |
| OLFML3 | olfactomedin-like 3 |
| PIGH | phosphatidylinositol glycan anchor biosynthesis, class H |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PLD3 | phospholipase D family, member 3 |
| PTDSS2 | phosphatidylserine synthase 2 |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RBM23 | RNA binding motif protein 23 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| SCAMP5 | secretory carrier membrane protein 5 |
| SCML1 | sex comb on midleg-like 1 (Drosophila) |
| SCML2 | sex comb on midleg-like 2 (Drosophila) |
| SECISBP2 | SECIS binding protein 2 |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SH2D4A | SH2 domain containing 4A |
| SLC27A5 | solute carrier family 27 (fatty acid transporter), member 5 |
| SLC46A3 | solute carrier family 46, member 3 |
| SMARCAL1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 |
| SNORA21 | small nucleolar RNA, H/ACA box 21 |
| SSFA2 | sperm specific antigen 2 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| THOP1 | thimet oligopeptidase 1 |
| TMEM134 | transmembrane protein 134 |
| TMEM177 | transmembrane protein 177 |
| TNFSF13 | tumor necrosis factor (ligand) superfamily, member 13 |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 |
| TPST2 | tyrosylprotein sulfotransferase 2 |
| TRAIP | TRAF interacting protein |
| TRIM45 | tripartite motif containing 45 |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| TUBA3C | tubulin, alpha 3c |
| UBXN6 | UBX domain protein 6 |
| URB2 | URB2 ribosome biogenesis 2 homolog (S. cerevisiae) |
| USP18 | ubiquitin specific peptidase 18 |
| USP36 | ubiquitin specific peptidase 36 |
| ZNF254 | zinc finger protein 254 |
| ZNF276 | zinc finger protein 276 |
| ZNF408 | zinc finger protein 408 |
| ZNF623 | zinc finger protein 623 |
| ZNF675 | zinc finger protein 675 |
| ZSCAN5A | zinc finger and SCAN domain containing 5A |
