butacaine Gene Set

Dataset LINCS L1000 CMAP Chemical Perturbation Consensus Signatures
Category transcriptomics
Type small molecule perturbation
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Genes

14 genes differentially expressed following the butacaine small molecule perturbation from the LINCS L1000 CMAP Chemical Perturbation Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
CASP10 caspase 10, apoptosis-related cysteine peptidase 4.17957
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 4.04222
AMZ2 archaelysin family metallopeptidase 2 3.34335
ST8SIA1 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 3.33345
SIRT3 sirtuin 3 3.27015
ZNF34 zinc finger protein 34 3.07229
STXBP1 syntaxin binding protein 1 3.06035
DZIP3 DAZ interacting zinc finger protein 3 3.02375

decreased expression

Symbol Name Standardized Value
EPHB2 EPH receptor B2 -4.78224
VPREB3 pre-B lymphocyte 3 -3.41463
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide -3.34705
BID BH3 interacting domain death agonist -3.3424
AHDC1 AT hook, DNA binding motif, containing 1 -3.15302
KCNJ9 potassium channel, inwardly rectifying subfamily J, member 9 -3.10695