butamben-2531 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the butamben-2531 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD2 abhydrolase domain containing 2
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ADRA1A adrenoceptor alpha 1A
AEN apoptosis enhancing nuclease
AHNAK AHNAK nucleoprotein
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
APAF1 apoptotic peptidase activating factor 1
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
APP amyloid beta (A4) precursor protein
ARMC4 armadillo repeat containing 4
ATP2A3 ATPase, Ca++ transporting, ubiquitous
B4GALT6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6
BBS9 Bardet-Biedl syndrome 9
BMP8B bone morphogenetic protein 8b
BTG2 BTG family, member 2
BTN3A1 butyrophilin, subfamily 3, member A1
C1QTNF3 C1q and tumor necrosis factor related protein 3
C22ORF24 chromosome 22 open reading frame 24
CALCR calcitonin receptor
CASZ1 castor zinc finger 1
CDC14A cell division cycle 14A
CDC42 cell division cycle 42
COL9A2 collagen, type IX, alpha 2
COQ7 coenzyme Q7 homolog, ubiquinone (yeast)
CYHR1 cysteine/histidine-rich 1
DENND5B DENN/MADD domain containing 5B
DZANK1 double zinc ribbon and ankyrin repeat domains 1
EIF1 eukaryotic translation initiation factor 1
ELAC1 elaC ribonuclease Z 1
FAM46C family with sequence similarity 46, member C
FAM65A family with sequence similarity 65, member A
FBP1 fructose-1,6-bisphosphatase 1
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
GLRX3 glutaredoxin 3
HLA-DMA major histocompatibility complex, class II, DM alpha
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
IFNB1 interferon, beta 1, fibroblast
ING1 inhibitor of growth family, member 1
ING4 inhibitor of growth family, member 4
ITGB5 integrin, beta 5
KLF3 Kruppel-like factor 3 (basic)
LPAR1 lysophosphatidic acid receptor 1
MANSC1 MANSC domain containing 1
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MAPK1IP1L mitogen-activated protein kinase 1 interacting protein 1-like
MAPK7 mitogen-activated protein kinase 7
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MBNL2 muscleblind-like splicing regulator 2
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MED28 mediator complex subunit 28
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MYH14 myosin, heavy chain 14, non-muscle
N4BP2L2-IT2 N4BPL2 intronic transcript 2
NCKAP1L NCK-associated protein 1-like
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
NTNG1 netrin G1
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCSK6 proprotein convertase subtilisin/kexin type 6
PDE4D phosphodiesterase 4D, cAMP-specific
PDLIM1 PDZ and LIM domain 1
PECR peroxisomal trans-2-enoyl-CoA reductase
PER3 period circadian clock 3
PHF20L1 PHD finger protein 20-like 1
PKP1 plakophilin 1
PLD1 phospholipase D1, phosphatidylcholine-specific
PLXDC1 plexin domain containing 1
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
POFUT1 protein O-fucosyltransferase 1
PORCN porcupine homolog (Drosophila)
PVR poliovirus receptor
RNASE3 ribonuclease, RNase A family, 3
RND1 Rho family GTPase 1
RPL23AP32 ribosomal protein L23a pseudogene 32
RPL23AP7 ribosomal protein L23a pseudogene 7
SEC14L4 SEC14-like 4 (S. cerevisiae)
SENP7 SUMO1/sentrin specific peptidase 7
SIDT2 SID1 transmembrane family, member 2
SIGLEC5 sialic acid binding Ig-like lectin 5
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC25A30 solute carrier family 25, member 30
SMAD5 SMAD family member 5
SPTAN1 spectrin, alpha, non-erythrocytic 1
SRR serine racemase
ST14 suppression of tumorigenicity 14 (colon carcinoma)
STX2 syntaxin 2
TAPBP TAP binding protein (tapasin)
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TCP11L1 t-complex 11, testis-specific-like 1
TGFB1 transforming growth factor, beta 1
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TRD T cell receptor delta locus
TRPS1 trichorhinophalangeal syndrome I
TUBA4B tubulin, alpha 4b
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
ZER1 zyg-11 related, cell cycle regulator
ZNF446 zinc finger protein 446
ZNF76 zinc finger protein 76

decreased expression

Symbol Name
ADORA3 adenosine A3 receptor
AMDHD2 amidohydrolase domain containing 2
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
ATAT1 alpha tubulin acetyltransferase 1
BSPRY B-box and SPRY domain containing
C1ORF56 chromosome 1 open reading frame 56
CABP2 calcium binding protein 2
CCDC176 coiled-coil domain containing 176
CCDC57 coiled-coil domain containing 57
CD9 CD9 molecule
CDH10 cadherin 10, type 2 (T2-cadherin)
CDHR2 cadherin-related family member 2
CDR2L cerebellar degeneration-related protein 2-like
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal)
CNR2 cannabinoid receptor 2 (macrophage)
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CROT carnitine O-octanoyltransferase
CST1 cystatin SN
DBF4B DBF4 zinc finger B
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal
DNAH17 dynein, axonemal, heavy chain 17
EDAR ectodysplasin A receptor
EPHB6 EPH receptor B6
EXO5 exonuclease 5
FAM120C family with sequence similarity 120C
FAM131A family with sequence similarity 131, member A
FAM13C family with sequence similarity 13, member C
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
FCGRT Fc fragment of IgG, receptor, transporter, alpha
FKBP5 FK506 binding protein 5
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FRMPD1 FERM and PDZ domain containing 1
GIPR gastric inhibitory polypeptide receptor
GJA1 gap junction protein, alpha 1, 43kDa
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GSDMD gasdermin D
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HAMP hepcidin antimicrobial peptide
HIST1H2BG histone cluster 1, H2bg
HIST1H2BN histone cluster 1, H2bn
HRH2 histamine receptor H2
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFT140 intraflagellar transport 140
IFT81 intraflagellar transport 81
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2
IQSEC2 IQ motif and Sec7 domain 2
KCNA6 potassium channel, voltage gated shaker related subfamily A, member 6
KCNK5 potassium channel, two pore domain subfamily K, member 5
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2
KLF1 Kruppel-like factor 1 (erythroid)
KLHL36 kelch-like family member 36
KRT81 keratin 81, type II
LGALS4 lectin, galactoside-binding, soluble, 4
MEGF8 multiple EGF-like-domains 8
MGP matrix Gla protein
MTSS1L metastasis suppressor 1-like
MYBPH myosin binding protein H
MYO1E myosin IE
MYOC myocilin, trabecular meshwork inducible glucocorticoid response
NACA2 nascent polypeptide-associated complex alpha subunit 2
NAG18 NAG18 mRNA
NECAB3 N-terminal EF-hand calcium binding protein 3
NOTCH4 notch 4
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PCDH12 protocadherin 12
PIP prolactin-induced protein
POM121 POM121 transmembrane nucleoporin
PPT2 palmitoyl-protein thioesterase 2
PRO2964 uncharacterized protein PRO2964
PRSS21 protease, serine, 21 (testisin)
RANBP17 RAN binding protein 17
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RASAL1 RAS protein activator like 1 (GAP1 like)
RNF25 ring finger protein 25
SCUBE3 signal peptide, CUB domain, EGF-like 3
SIL1 SIL1 nucleotide exchange factor
SIRT6 sirtuin 6
SMR3A submaxillary gland androgen regulated protein 3A
SPATA1 spermatogenesis associated 1
SPEF1 sperm flagellar 1
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
STEAP4 STEAP family member 4
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TESPA1 thymocyte expressed, positive selection associated 1
TMEM212 transmembrane protein 212
TRIM45 tripartite motif containing 45
TSNAXIP1 translin-associated factor X interacting protein 1
VEGFC vascular endothelial growth factor C
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZBTB22 zinc finger and BTB domain containing 22
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZNF862 zinc finger protein 862