butamben-6093 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the butamben-6093 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GNT alpha-1,4-N-acetylglucosaminyltransferase
ACAP1 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
ACSBG2 acyl-CoA synthetase bubblegum family member 2
ALK anaplastic lymphoma receptor tyrosine kinase
AMPD1 adenosine monophosphate deaminase 1
ATP10B ATPase, class V, type 10B
ATP2A1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2
BTNL3 butyrophilin-like 3
C19ORF66 chromosome 19 open reading frame 66
C8ORF44 chromosome 8 open reading frame 44
CACNG1 calcium channel, voltage-dependent, gamma subunit 1
CCDC57 coiled-coil domain containing 57
CCDC88A coiled-coil domain containing 88A
CD3D CD3d molecule, delta (CD3-TCR complex)
CLCN6 chloride channel, voltage-sensitive 6
COL16A1 collagen, type XVI, alpha 1
COL8A1 collagen, type VIII, alpha 1
DCT dopachrome tautomerase
DGCR2 DiGeorge syndrome critical region gene 2
DGCR8 DGCR8 microprocessor complex subunit
DNASE1L3 deoxyribonuclease I-like 3
DOCK5 dedicator of cytokinesis 5
ELAC2 elaC ribonuclease Z 2
ELAVL4 ELAV like neuron-specific RNA binding protein 4
ESR1 estrogen receptor 1
F13A1 coagulation factor XIII, A1 polypeptide
FABP6 fatty acid binding protein 6, ileal
FAM46C family with sequence similarity 46, member C
FAT4 FAT atypical cadherin 4
FRMD4B FERM domain containing 4B
FXYD2 FXYD domain containing ion transport regulator 2
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GBP2 guanylate binding protein 2, interferon-inducible
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type
GP5 glycoprotein V (platelet)
GREB1L growth regulation by estrogen in breast cancer-like
GRIK5 glutamate receptor, ionotropic, kainate 5
GRK4 G protein-coupled receptor kinase 4
GSAP gamma-secretase activating protein
GSTTP1 glutathione S-transferase theta pseudogene 1
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
ICAM1 intercellular adhesion molecule 1
ICOSLG inducible T-cell co-stimulator ligand
IL11 interleukin 11
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KIAA0040 KIAA0040
KLK1 kallikrein 1
LAMP1 lysosomal-associated membrane protein 1
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
LY9 lymphocyte antigen 9
MALL mal, T-cell differentiation protein-like
MAP3K13 mitogen-activated protein kinase kinase kinase 13
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2
MARS methionyl-tRNA synthetase
MMRN2 multimerin 2
MTAP methylthioadenosine phosphorylase
MUC3B mucin 3B, cell surface associated
MYL10 myosin, light chain 10, regulatory
MYOZ1 myozenin 1
NDUFA2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa
OLFML2B olfactomedin-like 2B
PLK3 polo-like kinase 3
PPEF1 protein phosphatase, EF-hand calcium binding domain 1
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme
PRAMEF11 PRAME family member 11
PRB1 proline-rich protein BstNI subfamily 1
PRKCE protein kinase C, epsilon
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PTTG2 pituitary tumor-transforming 2
RAB3B RAB3B, member RAS oncogene family
RHBG Rh family, B glycoprotein (gene/pseudogene)
RIN3 Ras and Rab interactor 3
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
RYR1 ryanodine receptor 1 (skeletal)
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin
SIRT4 sirtuin 4
SIRT5 sirtuin 5
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SNTA1 syntrophin, alpha 1
SOAT2 sterol O-acyltransferase 2
SPIB Spi-B transcription factor (Spi-1/PU.1 related)
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TFR2 transferrin receptor 2
TMPRSS6 transmembrane protease, serine 6
UBA6 ubiquitin-like modifier activating enzyme 6
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
WTAP Wilms tumor 1 associated protein
ZFP64 ZFP64 zinc finger protein
ZNF235 zinc finger protein 235
ZNF646 zinc finger protein 646
ZSWIM1 zinc finger, SWIM-type containing 1

decreased expression

Symbol Name
ACYP2 acylphosphatase 2, muscle type
ADAM23 ADAM metallopeptidase domain 23
AFAP1 actin filament associated protein 1
AGMAT agmatine ureohydrolase (agmatinase)
ALPK1 alpha-kinase 1
AMT aminomethyltransferase
ARHGAP4 Rho GTPase activating protein 4
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
B9D2 B9 protein domain 2
BBC3 BCL2 binding component 3
C17ORF70 chromosome 17 open reading frame 70
C2ORF54 chromosome 2 open reading frame 54
C3ORF18 chromosome 3 open reading frame 18
C5ORF45 chromosome 5 open reading frame 45
C7ORF43 chromosome 7 open reading frame 43
CA5BP1 carbonic anhydrase VB pseudogene 1
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CENPO centromere protein O
CIDEB cell death-inducing DFFA-like effector b
CSF1R colony stimulating factor 1 receptor
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DRD1 dopamine receptor D1
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EGFL7 EGF-like-domain, multiple 7
ERN1 endoplasmic reticulum to nucleus signaling 1
ETNK2 ethanolamine kinase 2
F3 coagulation factor III (thromboplastin, tissue factor)
FBRS fibrosin
FER fer (fps/fes related) tyrosine kinase
GADD45G growth arrest and DNA-damage-inducible, gamma
GMEB1 glucocorticoid modulatory element binding protein 1
GRB7 growth factor receptor-bound protein 7
HAMP hepcidin antimicrobial peptide
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
IFIT5 interferon-induced protein with tetratricopeptide repeats 5
IFNAR1 interferon (alpha, beta and omega) receptor 1
IFT54 intraflagellar transport 54
IL4R interleukin 4 receptor
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KIF13B kinesin family member 13B
KLHL25 kelch-like family member 25
KLHL28 kelch-like family member 28
LMO2 LIM domain only 2 (rhombotin-like 1)
LOC257152 uncharacterized LOC257152
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LRRC61 leucine rich repeat containing 61
LTBP2 latent transforming growth factor beta binding protein 2
LY6D lymphocyte antigen 6 complex, locus D
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MSI1 musashi RNA-binding protein 1
MTHFS 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
MYLK myosin light chain kinase
NT5E 5'-nucleotidase, ecto (CD73)
OR1D2 olfactory receptor, family 1, subfamily D, member 2
OSGIN1 oxidative stress induced growth inhibitor 1
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
PACS1 phosphofurin acidic cluster sorting protein 1
PCDHA5 protocadherin alpha 5
PDE8B phosphodiesterase 8B
PICK1 protein interacting with PRKCA 1
PLEKHA6 pleckstrin homology domain containing, family A member 6
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PLEKHO2 pleckstrin homology domain containing, family O member 2
POMT2 protein-O-mannosyltransferase 2
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1
PRPH peripherin
PTK6 protein tyrosine kinase 6
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
RAB3D RAB3D, member RAS oncogene family
RAB40C RAB40C, member RAS oncogene family
RFXAP regulatory factor X-associated protein
RNF126P1 ring finger protein 126 pseudogene 1
RUSC2 RUN and SH3 domain containing 2
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
STRA6 stimulated by retinoic acid 6
TLN1 talin 1
TMCC2 transmembrane and coiled-coil domain family 2
TMEM158 transmembrane protein 158 (gene/pseudogene)
TMLHE trimethyllysine hydroxylase, epsilon
TRIM21 tripartite motif containing 21
TRMT13 tRNA methyltransferase 13 homolog (S. cerevisiae)
TTBK2 tau tubulin kinase 2
UBXN6 UBX domain protein 6
USB1 U6 snRNA biogenesis 1
VAX2 ventral anterior homeobox 2
VEGFB vascular endothelial growth factor B
WDR62 WD repeat domain 62
XAB2 XPA binding protein 2
XYLT1 xylosyltransferase I
ZBTB48 zinc finger and BTB domain containing 48
ZDHHC18 zinc finger, DHHC-type containing 18
ZNF324 zinc finger protein 324
ZNF492 zinc finger protein 492