butamben-6266 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the butamben-6266 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACVR1B activin A receptor, type IB
ADAM17 ADAM metallopeptidase domain 17
AGFG2 ArfGAP with FG repeats 2
ALPK1 alpha-kinase 1
ATG3 autophagy related 3
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BMP2K BMP2 inducible kinase
BRCA2 breast cancer 2, early onset
BSDC1 BSD domain containing 1
BST2 bone marrow stromal cell antigen 2
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
C14ORF93 chromosome 14 open reading frame 93
C7ORF43 chromosome 7 open reading frame 43
CASP1 caspase 1, apoptosis-related cysteine peptidase
CASP3 caspase 3, apoptosis-related cysteine peptidase
CHMP6 charged multivesicular body protein 6
COPS7B COP9 signalosome subunit 7B
CUL4B cullin 4B
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
DCAF17 DDB1 and CUL4 associated factor 17
DGKE diacylglycerol kinase, epsilon 64kDa
EAF2 ELL associated factor 2
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
FAM134B family with sequence similarity 134, member B
FAM46C family with sequence similarity 46, member C
FBXL4 F-box and leucine-rich repeat protein 4
FBXO11 F-box protein 11
FH fumarate hydratase
GALK1 galactokinase 1
GMEB1 glucocorticoid modulatory element binding protein 1
GREB1 growth regulation by estrogen in breast cancer 1
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2
HMOX1 heme oxygenase 1
IFI6 interferon, alpha-inducible protein 6
IFT54 intraflagellar transport 54
IL27RA interleukin 27 receptor, alpha
IRF9 interferon regulatory factor 9
ISG15 ISG15 ubiquitin-like modifier
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
KIAA0040 KIAA0040
KLHL25 kelch-like family member 25
KREMEN2 kringle containing transmembrane protein 2
LAMC2 laminin, gamma 2
LAMP1 lysosomal-associated membrane protein 1
MAP2K2 mitogen-activated protein kinase kinase 2
MAP3K12 mitogen-activated protein kinase kinase kinase 12
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MICALL1 MICAL-like 1
MPDZ multiple PDZ domain protein
MUC3B mucin 3B, cell surface associated
NCBP1 nuclear cap binding protein subunit 1, 80kDa
NDUFB8 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa
NFE2L3 nuclear factor, erythroid 2-like 3
NID1 nidogen 1
NOD2 nucleotide-binding oligomerization domain containing 2
PDE3B phosphodiesterase 3B, cGMP-inhibited
PDE4A phosphodiesterase 4A, cAMP-specific
PGAP1 post-GPI attachment to proteins 1
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PLK4 polo-like kinase 4
PLSCR3 phospholipid scramblase 3
PPT2 palmitoyl-protein thioesterase 2
PRKCA protein kinase C, alpha
PRKD3 protein kinase D3
PTPN2 protein tyrosine phosphatase, non-receptor type 2
QKI QKI, KH domain containing, RNA binding
RBL1 retinoblastoma-like 1
RCAN1 regulator of calcineurin 1
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RNF122 ring finger protein 122
RPS9 ribosomal protein S9
SAP30 Sin3A-associated protein, 30kDa
SEC14L2 SEC14-like 2 (S. cerevisiae)
SLC25A44 solute carrier family 25, member 44
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SOWAHC sosondowah ankyrin repeat domain family member C
SOX9 SRY (sex determining region Y)-box 9
SPINK4 serine peptidase inhibitor, Kazal type 4
SPTAN1 spectrin, alpha, non-erythrocytic 1
STAG3 stromal antigen 3
STAT1 signal transducer and activator of transcription 1, 91kDa
TICAM1 toll-like receptor adaptor molecule 1
TMCC2 transmembrane and coiled-coil domain family 2
TMPRSS3 transmembrane protease, serine 3
TSPAN3 tetraspanin 3
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28
USP27X ubiquitin specific peptidase 27, X-linked
VIPR2 vasoactive intestinal peptide receptor 2
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
ZBTB48 zinc finger and BTB domain containing 48
ZNF286A zinc finger protein 286A
ZNF329 zinc finger protein 329
ZNF573 zinc finger protein 573
ZNF675 zinc finger protein 675
ZSWIM8 zinc finger, SWIM-type containing 8

decreased expression

Symbol Name
ADGRE5 adhesion G protein-coupled receptor E5
AEN apoptosis enhancing nuclease
ANKFY1 ankyrin repeat and FYVE domain containing 1
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ARL15 ADP-ribosylation factor-like 15
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
AXIN1 axin 1
BATF basic leucine zipper transcription factor, ATF-like
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BHLHB9 basic helix-loop-helix domain containing, class B, 9
BTF3P12 basic transcription factor 3 pseudogene 12
C22ORF29 chromosome 22 open reading frame 29
C6ORF47 chromosome 6 open reading frame 47
CAPN5 calpain 5
CCDC186 coiled-coil domain containing 186
CLASRP CLK4-associating serine/arginine rich protein
CLCN2 chloride channel, voltage-sensitive 2
CNGB3 cyclic nucleotide gated channel beta 3
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CNR2 cannabinoid receptor 2 (macrophage)
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DSCAM Down syndrome cell adhesion molecule
ELOVL4 ELOVL fatty acid elongase 4
EPHA2 EPH receptor A2
FAM53B family with sequence similarity 53, member B
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2
GAS8 growth arrest-specific 8
GLB1L2 galactosidase, beta 1-like 2
GLI3 GLI family zinc finger 3
GLS2 glutaminase 2 (liver, mitochondrial)
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HIST1H1D histone cluster 1, H1d
HOXC13 homeobox C13
IGSF1 immunoglobulin superfamily, member 1
IL17RA interleukin 17 receptor A
IL2 interleukin 2
INO80D INO80 complex subunit D
KCNMB4 potassium channel subfamily M regulatory beta subunit 4
KDM5C lysine (K)-specific demethylase 5C
KIZ kizuna centrosomal protein
KLHL21 kelch-like family member 21
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LMCD1 LIM and cysteine-rich domains 1
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MED15 mediator complex subunit 15
MEFV Mediterranean fever
MFSD12 major facilitator superfamily domain containing 12
MITF microphthalmia-associated transcription factor
MYO1D myosin ID
MYO1E myosin IE
NRGN neurogranin (protein kinase C substrate, RC3)
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PCSK7 proprotein convertase subtilisin/kexin type 7
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PLD3 phospholipase D family, member 3
PMP22 peripheral myelin protein 22
PODXL2 podocalyxin-like 2
POMT2 protein-O-mannosyltransferase 2
PRR3 proline rich 3
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAB8B RAB8B, member RAS oncogene family
RGS19 regulator of G-protein signaling 19
RIBC2 RIB43A domain with coiled-coils 2
RNF126P1 ring finger protein 126 pseudogene 1
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RPAP1 RNA polymerase II associated protein 1
S100A4 S100 calcium binding protein A4
SCGB2A2 secretoglobin, family 2A, member 2
SETD8 SET domain containing (lysine methyltransferase) 8
SIRT6 sirtuin 6
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SMR3A submaxillary gland androgen regulated protein 3A
SND1-IT1 SND1 intronic transcript 1
SOX3 SRY (sex determining region Y)-box 3
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
SYCP2 synaptonemal complex protein 2
TAOK1 TAO kinase 1
TFF2 trefoil factor 2
TMEM2 transmembrane protein 2
TPST1 tyrosylprotein sulfotransferase 1
TPST2 tyrosylprotein sulfotransferase 2
TSPAN14 tetraspanin 14
USP18 ubiquitin specific peptidase 18
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
VGF VGF nerve growth factor inducible
VN1R1 vomeronasal 1 receptor 1
WDR19 WD repeat domain 19
XAB2 XPA binding protein 2
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZNF205 zinc finger protein 205
ZNF248 zinc finger protein 248
ZNF254 zinc finger protein 254
ZNF442 zinc finger protein 442