butein-582 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the butein-582 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AK1 adenylate kinase 1
ALX3 ALX homeobox 3
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
BATF3 basic leucine zipper transcription factor, ATF-like 3
BCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide
CA14 carbonic anhydrase XIV
CASP10 caspase 10, apoptosis-related cysteine peptidase
CASR calcium-sensing receptor
CD83 CD83 molecule
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CIITA class II, major histocompatibility complex, transactivator
CNPPD1 cyclin Pas1/PHO80 domain containing 1
CORO1B coronin, actin binding protein, 1B
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DHRS9 dehydrogenase/reductase (SDR family) member 9
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DUSP7 dual specificity phosphatase 7
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
EVPL envoplakin
FBXL18 F-box and leucine-rich repeat protein 18
FGFR1 fibroblast growth factor receptor 1
FKBP8 FK506 binding protein 8, 38kDa
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GALR3 galanin receptor 3
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5
GLP1R glucagon-like peptide 1 receptor
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GPR107 G protein-coupled receptor 107
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMOX1 heme oxygenase 1
HR hair growth associated
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
IGF1 insulin-like growth factor 1 (somatomedin C)
IGKV1D-13 immunoglobulin kappa variable 1D-13
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL1RN interleukin 1 receptor antagonist
INE1 inactivation escape 1 (non-protein coding)
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
KLF6 Kruppel-like factor 6
KNOP1 lysine-rich nucleolar protein 1
LEFTY1 left-right determination factor 1
LLGL1 lethal giant larvae homolog 1 (Drosophila)
LRP6 low density lipoprotein receptor-related protein 6
LTB4R leukotriene B4 receptor
MBNL2 muscleblind-like splicing regulator 2
MED31 mediator complex subunit 31
MLXIPL MLX interacting protein-like
MYO15B myosin XVB
NABP2 nucleic acid binding protein 2
NCKIPSD NCK interacting protein with SH3 domain
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NOL6 nucleolar protein 6 (RNA-associated)
NOTCH3 notch 3
PADI4 peptidyl arginine deiminase, type IV
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PC pyruvate carboxylase
PCGF1 polycomb group ring finger 1
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PER1 period circadian clock 1
PER3 period circadian clock 3
PIDD1 p53-induced death domain protein 1
PKD2L1 polycystic kidney disease 2-like 1
PLA2G5 phospholipase A2, group V
PLD3 phospholipase D family, member 3
PLEKHO2 pleckstrin homology domain containing, family O member 2
PLIN2 perilipin 2
RAB11B RAB11B, member RAS oncogene family
RNASEH2B ribonuclease H2, subunit B
RNGTT RNA guanylyltransferase and 5'-phosphatase
RPL13P5 ribosomal protein L13 pseudogene 5
RPLP2 ribosomal protein, large, P2
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6
SEMA3G sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SIT1 signaling threshold regulating transmembrane adaptor 1
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SMYD5 SMYD family member 5
SPAG4 sperm associated antigen 4
SPRR1B small proline-rich protein 1B
SQSTM1 sequestosome 1
SRSF1 serine/arginine-rich splicing factor 1
STAT5A signal transducer and activator of transcription 5A
STC2 stanniocalcin 2
SURF2 surfeit 2
TRA T cell receptor alpha locus
TRAC T cell receptor alpha constant
WDR61 WD repeat domain 61
YPEL1 yippee-like 1 (Drosophila)
ZFHX3 zinc finger homeobox 3
ZGPAT zinc finger, CCCH-type with G patch domain
ZNF219 zinc finger protein 219
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

decreased expression

Symbol Name
A4GNT alpha-1,4-N-acetylglucosaminyltransferase
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3
ADGRB2 adhesion G protein-coupled receptor B2
AHSP alpha hemoglobin stabilizing protein
ANAPC10 anaphase promoting complex subunit 10
ANAPC2 anaphase promoting complex subunit 2
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2
ATP1B2 ATPase, Na+/K+ transporting, beta 2 polypeptide
AXIN1 axin 1
BAHCC1 BAH domain and coiled-coil containing 1
C10ORF88 chromosome 10 open reading frame 88
C19ORF57 chromosome 19 open reading frame 57
CA6 carbonic anhydrase VI
CD2AP CD2-associated protein
CD79A CD79a molecule, immunoglobulin-associated alpha
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CLDN17 claudin 17
CLDND1 claudin domain containing 1
CNPY3 canopy FGF signaling regulator 3
CNTN1 contactin 1
CTRC chymotrypsin C (caldecrin)
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24
DNASE1L3 deoxyribonuclease I-like 3
EFNB3 ephrin-B3
ELAVL2 ELAV like neuron-specific RNA binding protein 2
EN2 engrailed homeobox 2
ERCC2 excision repair cross-complementation group 2
EVX1 even-skipped homeobox 1
F13A1 coagulation factor XIII, A1 polypeptide
FKBP10 FK506 binding protein 10, 65 kDa
FRMD1 FERM domain containing 1
GATA6 GATA binding protein 6
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C
GBX2 gastrulation brain homeobox 2
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GPR21 G protein-coupled receptor 21
GPR87 G protein-coupled receptor 87
GYPC glycophorin C (Gerbich blood group)
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HDAC5 histone deacetylase 5
HIST1H2AI histone cluster 1, H2ai
HP1BP3 heterochromatin protein 1, binding protein 3
IL36RN interleukin 36 receptor antagonist
INCENP inner centromere protein antigens 135/155kDa
KCNJ14 potassium channel, inwardly rectifying subfamily J, member 14
KIAA1462 KIAA1462
KIF23 kinesin family member 23
KIF3B kinesin family member 3B
KLHL26 kelch-like family member 26
LMTK1 lemur tail kinase 1
LUZP1 leucine zipper protein 1
LYPD3 LY6/PLAUR domain containing 3
MAGEC1 melanoma antigen family C1
MAL mal, T-cell differentiation protein
MAMLD1 mastermind-like domain containing 1
MICB MHC class I polypeptide-related sequence B
MKL2 MKL/myocardin-like 2
MYO1A myosin IA
NAP1L2 nucleosome assembly protein 1-like 2
NARS2 asparaginyl-tRNA synthetase 2, mitochondrial (putative)
NID2 nidogen 2 (osteonidogen)
NMD3 NMD3 ribosome export adaptor
NMI N-myc (and STAT) interactor
NNAT neuronatin
PAIP2B poly(A) binding protein interacting protein 2B
PAK1IP1 PAK1 interacting protein 1
PCDHA5 protocadherin alpha 5
PLBD1 phospholipase B domain containing 1
POLD1 polymerase (DNA directed), delta 1, catalytic subunit
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1
PRF1 perforin 1 (pore forming protein)
PRLH prolactin releasing hormone
PRMT3 protein arginine methyltransferase 3
PTX3 pentraxin 3, long
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
RAP1A RAP1A, member of RAS oncogene family
RGS17 regulator of G-protein signaling 17
RIN2 Ras and Rab interactor 2
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SNAPC4 small nuclear RNA activating complex, polypeptide 4, 190kDa
SNRNP35 small nuclear ribonucleoprotein 35kDa (U11/U12)
STARD5 StAR-related lipid transfer (START) domain containing 5
T T, brachyury homolog (mouse)
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TOMM22 translocase of outer mitochondrial membrane 22 homolog (yeast)
TPSG1 tryptase gamma 1
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRAPPC12 trafficking protein particle complex 12
TRHDE thyrotropin-releasing hormone degrading enzyme
TRIM58 tripartite motif containing 58
TRMT12 tRNA methyltransferase 12 homolog (S. cerevisiae)
UNC119B unc-119 homolog B (C. elegans)
VASH2 vasohibin 2
WNT5A wingless-type MMTV integration site family, member 5A
ZBTB22 zinc finger and BTB domain containing 22
ZNF23 zinc finger protein 23
ZNF668 zinc finger protein 668