butirosin-2518 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the butirosin-2518 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADRB1 adrenoceptor beta 1
ANKH ANKH inorganic pyrophosphate transport regulator
APAF1 apoptotic peptidase activating factor 1
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ARHGAP35 Rho GTPase activating protein 35
ATN1 atrophin 1
ATP9A ATPase, class II, type 9A
BANK1 B-cell scaffold protein with ankyrin repeats 1
C8A complement component 8, alpha polypeptide
CADM3 cell adhesion molecule 3
CALD1 caldesmon 1
CCL16 chemokine (C-C motif) ligand 16
CD160 CD160 molecule
CD47 CD47 molecule
CGA glycoprotein hormones, alpha polypeptide
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
COL7A1 collagen, type VII, alpha 1
CRYGD crystallin, gamma D
CTAG2 cancer/testis antigen 2
DGKA diacylglycerol kinase, alpha 80kDa
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DYRK1B dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
EML2 echinoderm microtubule associated protein like 2
EPHA3 EPH receptor A3
FBN1 fibrillin 1
FERMT1 fermitin family member 1
FRS3 fibroblast growth factor receptor substrate 3
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GJD2 gap junction protein, delta 2, 36kDa
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
GPR107 G protein-coupled receptor 107
GPR15 G protein-coupled receptor 15
GPR21 G protein-coupled receptor 21
GYPB glycophorin B (MNS blood group)
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HLA-DMA major histocompatibility complex, class II, DM alpha
ICA1 islet cell autoantigen 1, 69kDa
ICOSLG inducible T-cell co-stimulator ligand
IDI2-AS1 IDI2 antisense RNA 1
IFITM1 interferon induced transmembrane protein 1
IGHA1 immunoglobulin heavy constant alpha 1
IGHM immunoglobulin heavy constant mu
ISG20L2 interferon stimulated exonuclease gene 20kDa-like 2
KIAA0509 uncharacterized LOC57242
KIAA1109 KIAA1109
KIF5A kinesin family member 5A
KLF12 Kruppel-like factor 12
LECT1 leukocyte cell derived chemotaxin 1
LHX1 LIM homeobox 1
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
LINC00216 long intergenic non-protein coding RNA 216
LTBP2 latent transforming growth factor beta binding protein 2
MB myoglobin
MEG3 maternally expressed 3 (non-protein coding)
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
NEBL nebulette
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PCDH11Y protocadherin 11 Y-linked
PHF20L1 PHD finger protein 20-like 1
PLK4 polo-like kinase 4
POFUT1 protein O-fucosyltransferase 1
POM121L9P POM121 transmembrane nucleoporin-like 9, pseudogene
PPM1E protein phosphatase, Mg2+/Mn2+ dependent, 1E
PPP1R2P9 protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9
PRKCA protein kinase C, alpha
PTCRA pre T-cell antigen receptor alpha
RECQL5 RecQ protein-like 5
RGS5 regulator of G-protein signaling 5
RPL23AP32 ribosomal protein L23a pseudogene 32
RPS4Y1 ribosomal protein S4, Y-linked 1
SAA4 serum amyloid A4, constitutive
SCG2 secretogranin II
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SIGLEC7 sialic acid binding Ig-like lectin 7
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter)
SLC17A4 solute carrier family 17, member 4
SMURF1 SMAD specific E3 ubiquitin protein ligase 1
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding)
SPDEF SAM pointed domain containing ETS transcription factor
SPINK5 serine peptidase inhibitor, Kazal type 5
SPTAN1 spectrin, alpha, non-erythrocytic 1
STAP1 signal transducing adaptor family member 1
TAT tyrosine aminotransferase
TBX5 T-box 5
TEF thyrotrophic embryonic factor
TGFB2 transforming growth factor, beta 2
THPO thrombopoietin
TLK1 tousled-like kinase 1
TMOD1 tropomodulin 1
TRIM25 tripartite motif containing 25
TUBB1 tubulin, beta 1 class VI
USP6NL USP6 N-terminal like
ZNF76 zinc finger protein 76
ZNF771 zinc finger protein 771
ZXDB zinc finger, X-linked, duplicated B

decreased expression

Symbol Name
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ADGRA3 adhesion G protein-coupled receptor A3
ALG12 ALG12, alpha-1,6-mannosyltransferase
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ALS2CL ALS2 C-terminal like
AMDHD2 amidohydrolase domain containing 2
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
ARG1 arginase 1
ARHGAP12 Rho GTPase activating protein 12
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
ARSB arylsulfatase B
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BBS7 Bardet-Biedl syndrome 7
C5 complement component 5
CCDC106 coiled-coil domain containing 106
CD151 CD151 molecule (Raph blood group)
CD70 CD70 molecule
CD9 CD9 molecule
CDADC1 cytidine and dCMP deaminase domain containing 1
CDH10 cadherin 10, type 2 (T2-cadherin)
CDIP1 cell death-inducing p53 target 1
CEP97 centrosomal protein 97kDa
CHMP7 charged multivesicular body protein 7
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal)
CTNNBIP1 catenin, beta interacting protein 1
CTRL chymotrypsin-like
CTSO cathepsin O
CXORF56 chromosome X open reading frame 56
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DNAL4 dynein, axonemal, light chain 4
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DOK3 docking protein 3
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
FAM86C1 family with sequence similarity 86, member C1
FLRT2 fibronectin leucine rich transmembrane protein 2
FOXRED2 FAD-dependent oxidoreductase domain containing 2
GAA glucosidase, alpha; acid
GMPPB GDP-mannose pyrophosphorylase B
GSTCD glutathione S-transferase, C-terminal domain containing
GTF2H4 general transcription factor IIH, polypeptide 4, 52kDa
HAMP hepcidin antimicrobial peptide
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
KCNK5 potassium channel, two pore domain subfamily K, member 5
KDM4C lysine (K)-specific demethylase 4C
KLHL36 kelch-like family member 36
KRT81 keratin 81, type II
LIME1 Lck interacting transmembrane adaptor 1
MCOLN1 mucolipin 1
MED15 mediator complex subunit 15
MEGF8 multiple EGF-like-domains 8
METTL2B methyltransferase like 2B
MITF microphthalmia-associated transcription factor
MYL5 myosin, light chain 5, regulatory
NARFL nuclear prelamin A recognition factor-like
NNAT neuronatin
NR1H2 nuclear receptor subfamily 1, group H, member 2
NT5C 5', 3'-nucleotidase, cytosolic
OLAH oleoyl-ACP hydrolase
PAQR6 progestin and adipoQ receptor family member VI
PLA2G12A phospholipase A2, group XIIA
PLA2G15 phospholipase A2, group XV
POLM polymerase (DNA directed), mu
POTEKP POTE ankyrin domain family, member K, pseudogene
PRR14L proline rich 14-like
PSKH1 protein serine kinase H1
RAB13 RAB13, member RAS oncogene family
RAPSN receptor-associated protein of the synapse
REEP4 receptor accessory protein 4
RHOBTB2 Rho-related BTB domain containing 2
RINT1 RAD50 interactor 1
SFXN1 sideroflexin 1
SGMS1 sphingomyelin synthase 1
SH3GLB2 SH3-domain GRB2-like endophilin B2
SLC12A9 solute carrier family 12, member 9
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A
SNX15 sorting nexin 15
SNX16 sorting nexin 16
SPATA2L spermatogenesis associated 2-like
SPON2 spondin 2, extracellular matrix protein
SRD5A3 steroid 5 alpha-reductase 3
STAG3L4 stromal antigen 3-like 4 (pseudogene)
TBC1D17 TBC1 domain family, member 17
TBL3 transducin (beta)-like 3
THEM6 thioesterase superfamily member 6
TMBIM1 transmembrane BAX inhibitor motif containing 1
TMEM183A transmembrane protein 183A
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TNS2 tensin 2
TRAIP TRAF interacting protein
TTLL1 tubulin tyrosine ligase-like family member 1
TWSG1 twisted gastrulation BMP signaling modulator 1
UBE2O ubiquitin-conjugating enzyme E2O
USP19 ubiquitin specific peptidase 19
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF254 zinc finger protein 254
ZNF408 zinc finger protein 408
ZNF675 zinc finger protein 675
ZNF701 zinc finger protein 701
ZNF83 zinc finger protein 83