| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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194 genes differentially expressed following the butirosin-6080 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACAA2 | acetyl-CoA acyltransferase 2 |
| ADAM3A | ADAM metallopeptidase domain 3A (pseudogene) |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 |
| ALDOB | aldolase B, fructose-bisphosphate |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein |
| ANK1 | ankyrin 1, erythrocytic |
| APOE | apolipoprotein E |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 |
| ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
| ASCL1 | achaete-scute family bHLH transcription factor 1 |
| ATHL1 | ATH1, acid trehalase-like 1 (yeast) |
| ATXN8OS | ATXN8 opposite strand (non-protein coding) |
| BCL2 | B-cell CLL/lymphoma 2 |
| BMP1 | bone morphogenetic protein 1 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| C19ORF73 | chromosome 19 open reading frame 73 |
| C1QTNF1 | C1q and tumor necrosis factor related protein 1 |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) |
| CDRT1 | CMT1A duplicated region transcript 1 |
| CR1 | complement component (3b/4b) receptor 1 (Knops blood group) |
| CXCR4 | chemokine (C-X-C motif) receptor 4 |
| CYTH4 | cytohesin 4 |
| DMP1 | dentin matrix acidic phosphoprotein 1 |
| DOK2 | docking protein 2, 56kDa |
| DST | dystonin |
| EGR4 | early growth response 4 |
| ELOVL5 | ELOVL fatty acid elongase 5 |
| EPHB2 | EPH receptor B2 |
| EPYC | epiphycan |
| FABP3 | fatty acid binding protein 3, muscle and heart |
| FCAR | Fc fragment of IgA receptor |
| FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) |
| GPR153 | G protein-coupled receptor 153 |
| GRK5 | G protein-coupled receptor kinase 5 |
| GSDMD | gasdermin D |
| GSTTP1 | glutathione S-transferase theta pseudogene 1 |
| GUCA2B | guanylate cyclase activator 2B (uroguanylin) |
| GUCY1A2 | guanylate cyclase 1, soluble, alpha 2 |
| HNF4A | hepatocyte nuclear factor 4, alpha |
| HTR1F | 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled |
| HYAL1 | hyaluronoglucosaminidase 1 |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IGHM | immunoglobulin heavy constant mu |
| KHSRP | KH-type splicing regulatory protein |
| KIAA1467 | KIAA1467 |
| KIAA1644 | KIAA1644 |
| KIR2DS4 | killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 4 |
| KLF6 | Kruppel-like factor 6 |
| LAMA4 | laminin, alpha 4 |
| LAMB4 | laminin, beta 4 |
| LDB3 | LIM domain binding 3 |
| LEFTY2 | left-right determination factor 2 |
| LEPR | leptin receptor |
| LGALS8 | lectin, galactoside-binding, soluble, 8 |
| LPAR3 | lysophosphatidic acid receptor 3 |
| MAP4K2 | mitogen-activated protein kinase kinase kinase kinase 2 |
| MCPH1 | microcephalin 1 |
| MEG3 | maternally expressed 3 (non-protein coding) |
| MS4A1 | membrane-spanning 4-domains, subfamily A, member 1 |
| MYT1 | myelin transcription factor 1 |
| OLIG2 | oligodendrocyte lineage transcription factor 2 |
| PAX8 | paired box 8 |
| PCDHB1 | protocadherin beta 1 |
| PDGFRB | platelet-derived growth factor receptor, beta polypeptide |
| PDPN | podoplanin |
| PKNOX1 | PBX/knotted 1 homeobox 1 |
| POU3F4 | POU class 3 homeobox 4 |
| PPP1R1A | protein phosphatase 1, regulatory (inhibitor) subunit 1A |
| PRKAA2 | protein kinase, AMP-activated, alpha 2 catalytic subunit |
| PTGIS | prostaglandin I2 (prostacyclin) synthase |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 |
| RAB14 | RAB14, member RAS oncogene family |
| RBBP4 | retinoblastoma binding protein 4 |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
| RPH3A | rabphilin 3A |
| RSPH14 | radial spoke head 14 homolog (Chlamydomonas) |
| SAA3P | serum amyloid A3 pseudogene |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 |
| SIX3 | SIX homeobox 3 |
| SLAMF1 | signaling lymphocytic activation molecule family member 1 |
| SLC12A4 | solute carrier family 12 (potassium/chloride transporter), member 4 |
| SPN | sialophorin |
| TAGLN3 | transgelin 3 |
| THRB | thyroid hormone receptor, beta |
| TMOD1 | tropomodulin 1 |
| TMPRSS15 | transmembrane protease, serine 15 |
| TNFRSF13B | tumor necrosis factor receptor superfamily, member 13B |
| TRIL | TLR4 interactor with leucine-rich repeats |
| TTC38 | tetratricopeptide repeat domain 38 |
| UNC5B | unc-5 homolog B (C. elegans) |
| USP22 | ubiquitin specific peptidase 22 |
| VILL | villin-like |
| VNN1 | vanin 1 |
| WDR33 | WD repeat domain 33 |
| WNT8B | wingless-type MMTV integration site family, member 8B |
| ZFHX4 | zinc finger homeobox 4 |
| ZMYND10 | zinc finger, MYND-type containing 10 |
| Symbol | Name |
|---|---|
| ADAM23 | ADAM metallopeptidase domain 23 |
| ADCY6 | adenylate cyclase 6 |
| AFAP1 | actin filament associated protein 1 |
| AFF4 | AF4/FMR2 family, member 4 |
| ALS2CL | ALS2 C-terminal like |
| ARHGEF1 | Rho guanine nucleotide exchange factor (GEF) 1 |
| ARRB1 | arrestin, beta 1 |
| C5AR2 | complement component 5a receptor 2 |
| CBX7 | chromobox homolog 7 |
| CDKN2D | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) |
| CES3 | carboxylesterase 3 |
| CFAP45 | cilia and flagella associated protein 45 |
| CHKB | choline kinase beta |
| CIDEB | cell death-inducing DFFA-like effector b |
| CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
| CSF1R | colony stimulating factor 1 receptor |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
| CYP2B7P | cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene |
| ERCC6 | excision repair cross-complementation group 6 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 |
| FAM189A2 | family with sequence similarity 189, member A2 |
| FLJ11710 | uncharacterized protein FLJ11710 |
| FOXJ2 | forkhead box J2 |
| GAS6 | growth arrest-specific 6 |
| GMPR | guanosine monophosphate reductase |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GTPBP2 | GTP binding protein 2 |
| HDAC5 | histone deacetylase 5 |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H4F | histone cluster 1, H4f |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 |
| IFI35 | interferon-induced protein 35 |
| IFNAR1 | interferon (alpha, beta and omega) receptor 1 |
| IL12RB1 | interleukin 12 receptor, beta 1 |
| INPP5J | inositol polyphosphate-5-phosphatase J |
| IQCC | IQ motif containing C |
| KDM8 | lysine (K)-specific demethylase 8 |
| KIF13A | kinesin family member 13A |
| KIR2DS1 | killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1 |
| KPNA5 | karyopherin alpha 5 (importin alpha 6) |
| LAX1 | lymphocyte transmembrane adaptor 1 |
| LPXN | leupaxin |
| LRRC61 | leucine rich repeat containing 61 |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| LYL1 | lymphoblastic leukemia associated hematopoiesis regulator 1 |
| METTL2B | methyltransferase like 2B |
| MMP3 | matrix metallopeptidase 3 |
| MRPL52 | mitochondrial ribosomal protein L52 |
| MSI1 | musashi RNA-binding protein 1 |
| MYLK | myosin light chain kinase |
| NCALD | neurocalcin delta |
| NME5 | NME/NM23 family member 5 |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| NTF3 | neurotrophin 3 |
| PEX26 | peroxisomal biogenesis factor 26 |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 |
| PMCH | pro-melanin-concentrating hormone |
| POMT2 | protein-O-mannosyltransferase 2 |
| PPT2 | palmitoyl-protein thioesterase 2 |
| PTPRCAP | protein tyrosine phosphatase, receptor type, C-associated protein |
| QSER1 | glutamine and serine rich 1 |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RAB40C | RAB40C, member RAS oncogene family |
| RAPSN | receptor-associated protein of the synapse |
| RFXAP | regulatory factor X-associated protein |
| RLN1 | relaxin 1 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RUSC2 | RUN and SH3 domain containing 2 |
| S100A2 | S100 calcium binding protein A2 |
| SDC3 | syndecan 3 |
| SEMA6D | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D |
| SLC22A18AS | solute carrier family 22 (organic cation transporter), member 18 antisense |
| SMCO4 | single-pass membrane protein with coiled-coil domains 4 |
| SNX15 | sorting nexin 15 |
| STAG3 | stromal antigen 3 |
| STK16 | serine/threonine kinase 16 |
| SYT17 | synaptotagmin XVII |
| TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
| TARP | TCR gamma alternate reading frame protein |
| TCTN2 | tectonic family member 2 |
| TDRD7 | tudor domain containing 7 |
| TINF2 | TERF1 (TRF1)-interacting nuclear factor 2 |
| TMEM242 | transmembrane protein 242 |
| TNS2 | tensin 2 |
| TRIM21 | tripartite motif containing 21 |
| TUBA3C | tubulin, alpha 3c |
| UBQLN4 | ubiquilin 4 |
| VWA1 | von Willebrand factor A domain containing 1 |
| WDR62 | WD repeat domain 62 |
| WNT10B | wingless-type MMTV integration site family, member 10B |
| ZFYVE9 | zinc finger, FYVE domain containing 9 |
| ZIC3 | Zic family member 3 |
| ZNF10 | zinc finger protein 10 |
| ZNF606 | zinc finger protein 606 |
| ZNF804A | zinc finger protein 804A |
