butirosin-6779 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the butirosin-6779 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AKAP8L A kinase (PRKA) anchor protein 8-like
AKT3 v-akt murine thymoma viral oncogene homolog 3
ARTN artemin
BCO1 beta-carotene oxygenase 1
BLZF1 basic leucine zipper nuclear factor 1
BMP8B bone morphogenetic protein 8b
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
C14ORF79 chromosome 14 open reading frame 79
CALD1 caldesmon 1
CCDC71 coiled-coil domain containing 71
CCNK cyclin K
CFLAR CASP8 and FADD-like apoptosis regulator
CHKB choline kinase beta
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal)
COL6A1 collagen, type VI, alpha 1
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
DDR1-AS1 DDR1 antisense RNA 1 (head to head)
DGKB diacylglycerol kinase, beta 90kDa
E2F2 E2F transcription factor 2
EFNA3 ephrin-A3
EFNB3 ephrin-B3
EGFR epidermal growth factor receptor
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
ERAP1 endoplasmic reticulum aminopeptidase 1
F5 coagulation factor V (proaccelerin, labile factor)
FAM65A family with sequence similarity 65, member A
FEZ2 fasciculation and elongation protein zeta 2 (zygin II)
FGF22 fibroblast growth factor 22
GAP43 growth associated protein 43
GJA9 gap junction protein, alpha 9, 59kDa
GPR15 G protein-coupled receptor 15
GPR161 G protein-coupled receptor 161
GSAP gamma-secretase activating protein
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4
IL1B interleukin 1, beta
IL6R interleukin 6 receptor
IMPG2 interphotoreceptor matrix proteoglycan 2
ISL1 ISL LIM homeobox 1
KIAA0754 KIAA0754
KIAA1456 KIAA1456
KLF13 Kruppel-like factor 13
KRT16 keratin 16, type I
LIN7A lin-7 homolog A (C. elegans)
LOXL3 lysyl oxidase-like 3
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MINK1 misshapen-like kinase 1
MLANA melan-A
MMP19 matrix metallopeptidase 19
MRAS muscle RAS oncogene homolog
MZF1 myeloid zinc finger 1
N4BP1 NEDD4 binding protein 1
N4BP2L2-IT2 N4BPL2 intronic transcript 2
NDRG2 NDRG family member 2
NRSN2 neurensin 2
PAX9 paired box 9
PCDHA9 protocadherin alpha 9
PDLIM5 PDZ and LIM domain 5
PER3 period circadian clock 3
PGAP1 post-GPI attachment to proteins 1
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLIN2 perilipin 2
PLXND1 plexin D1
PPARA peroxisome proliferator-activated receptor alpha
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PQLC2 PQ loop repeat containing 2
PRKCE protein kinase C, epsilon
PTAFR platelet-activating factor receptor
PTHLH parathyroid hormone-like hormone
RBKS ribokinase
RBP4 retinol binding protein 4, plasma
RGS14 regulator of G-protein signaling 14
RTEL1 regulator of telomere elongation helicase 1
SAFB scaffold attachment factor B
SAYSD1 SAYSVFN motif domain containing 1
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
SMG5 SMG5 nonsense mediated mRNA decay factor
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SRSF5 serine/arginine-rich splicing factor 5
STAT5B signal transducer and activator of transcription 5B
STK24 serine/threonine kinase 24
TECPR2 tectonin beta-propeller repeat containing 2
TMPRSS2 transmembrane protease, serine 2
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TNS1 tensin 1
TTC28 tetratricopeptide repeat domain 28
UBAP1 ubiquitin associated protein 1
UBE3A ubiquitin protein ligase E3A
UBOX5 U-box domain containing 5
VASH2 vasohibin 2
WDR62 WD repeat domain 62
WFDC2 WAP four-disulfide core domain 2
WIZ widely interspaced zinc finger motifs
WNK1 WNK lysine deficient protein kinase 1
XYLB xylulokinase homolog (H. influenzae)
ZNF778 zinc finger protein 778
ZNF783 zinc finger family member 783
ZSCAN2 zinc finger and SCAN domain containing 2
ZSWIM8 zinc finger, SWIM-type containing 8

decreased expression

Symbol Name
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
ANKRD36 ankyrin repeat domain 36
ANO10 anoctamin 10
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
AUTS2 autism susceptibility candidate 2
BCL9 B-cell CLL/lymphoma 9
BGLAP bone gamma-carboxyglutamate (gla) protein
CCDC134 coiled-coil domain containing 134
CCDC69 coiled-coil domain containing 69
CENPC centromere protein C
CRYBB2P1 crystallin, beta B2 pseudogene 1
CSF1R colony stimulating factor 1 receptor
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DCAF10 DDB1 and CUL4 associated factor 10
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DOCK1 dedicator of cytokinesis 1
EDEM1 ER degradation enhancer, mannosidase alpha-like 1
EHMT1 euchromatic histone-lysine N-methyltransferase 1
ELAVL3 ELAV like neuron-specific RNA binding protein 3
FLRT3 fibronectin leucine rich transmembrane protein 3
GAMT guanidinoacetate N-methyltransferase
GATA4 GATA binding protein 4
GPR27 G protein-coupled receptor 27
GSTA4 glutathione S-transferase alpha 4
H2AFY2 H2A histone family, member Y2
HDAC7 histone deacetylase 7
HIST1H2AK histone cluster 1, H2ak
HLA-J major histocompatibility complex, class I, J (pseudogene)
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HOXC8 homeobox C8
ICK intestinal cell (MAK-like) kinase
IDI2-AS1 IDI2 antisense RNA 1
IFI6 interferon, alpha-inducible protein 6
IRF6 interferon regulatory factor 6
ISG20 interferon stimulated exonuclease gene 20kDa
KCNK15 potassium channel, two pore domain subfamily K, member 15
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LIME1 Lck interacting transmembrane adaptor 1
LYPLA2P1 lysophospholipase II pseudogene 1
MAST3 microtubule associated serine/threonine kinase 3
MDM4 MDM4, p53 regulator
MEFV Mediterranean fever
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MTERF4 mitochondrial transcription termination factor 4
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
NECAB3 N-terminal EF-hand calcium binding protein 3
NIPAL2 NIPA-like domain containing 2
NNAT neuronatin
NOTCH1 notch 1
OSGIN1 oxidative stress induced growth inhibitor 1
OSMR oncostatin M receptor
PCDH12 protocadherin 12
PCDHGB5 protocadherin gamma subfamily B, 5
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PELI1 pellino E3 ubiquitin protein ligase 1
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PLEKHA6 pleckstrin homology domain containing, family A member 6
PODXL2 podocalyxin-like 2
POTEKP POTE ankyrin domain family, member K, pseudogene
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRICKLE3 prickle homolog 3 (Drosophila)
PTPN6 protein tyrosine phosphatase, non-receptor type 6
QPCTL glutaminyl-peptide cyclotransferase-like
R3HCC1L R3H domain and coiled-coil containing 1-like
RALGPS1 Ral GEF with PH domain and SH3 binding motif 1
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RGS2 regulator of G-protein signaling 2
RPAP1 RNA polymerase II associated protein 1
SCAI suppressor of cancer cell invasion
SDC3 syndecan 3
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter)
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SLMO1 slowmo homolog 1 (Drosophila)
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SMR3A submaxillary gland androgen regulated protein 3A
STIM1 stromal interaction molecule 1
STMN3 stathmin-like 3
SYT17 synaptotagmin XVII
TCHH trichohyalin
TH tyrosine hydroxylase
THNSL1 threonine synthase-like 1 (S. cerevisiae)
TMEM104 transmembrane protein 104
TMEM53 transmembrane protein 53
TNS2 tensin 2
TRIM25 tripartite motif containing 25
TRIM5 tripartite motif containing 5
TTC33 tetratricopeptide repeat domain 33
UBQLN4 ubiquilin 4
VN1R1 vomeronasal 1 receptor 1
ZBTB22 zinc finger and BTB domain containing 22
ZDHHC11 zinc finger, DHHC-type containing 11
ZFP30 ZFP30 zinc finger protein
ZNF254 zinc finger protein 254
ZNF665 zinc finger protein 665
ZNF675 zinc finger protein 675