butoconazole-2427 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the butoconazole-2427 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A1CF APOBEC1 complementation factor
ACVR1B activin A receptor, type IB
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ATP10B ATPase, class V, type 10B
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CD47 CD47 molecule
CD80 CD80 molecule
CFAP69 cilia and flagella associated protein 69
CLCN4 chloride channel, voltage-sensitive 4
CLDN17 claudin 17
COLEC12 collectin sub-family member 12
COX11 COX11 cytochrome c oxidase copper chaperone
CPN2 carboxypeptidase N, polypeptide 2
CPTP ceramide-1-phosphate transfer protein
CRYGD crystallin, gamma D
CXXC4 CXXC finger protein 4
CYP4F2 cytochrome P450, family 4, subfamily F, polypeptide 2
DEFA4 defensin, alpha 4, corticostatin
EFR3B EFR3 homolog B (S. cerevisiae)
EIF1 eukaryotic translation initiation factor 1
ENDOD1 endonuclease domain containing 1
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
ETAA1 Ewing tumor-associated antigen 1
FBLN1 fibulin 1
FCMR Fc fragment of IgM receptor
FRMD8 FERM domain containing 8
GRHL2 grainyhead-like 2 (Drosophila)
HTR5A 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled
ICAM1 intercellular adhesion molecule 1
IFNA14 interferon, alpha 14
KCNG1 potassium channel, voltage gated modifier subfamily G, member 1
KLF3 Kruppel-like factor 3 (basic)
KRT24 keratin 24, type I
KRT8P12 keratin 8 pseudogene 12
KSR1 kinase suppressor of ras 1
LILRA1 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MAP1A microtubule-associated protein 1A
MCCC2 methylcrotonoyl-CoA carboxylase 2 (beta)
MERTK MER proto-oncogene, tyrosine kinase
METTL16 methyltransferase like 16
MFAP3 microfibrillar-associated protein 3
MORN1 MORN repeat containing 1
MPDZ multiple PDZ domain protein
MR1 major histocompatibility complex, class I-related
MTA1 metastasis associated 1
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2
NAG18 NAG18 mRNA
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NR1H3 nuclear receptor subfamily 1, group H, member 3
OTUB1 OTU deubiquitinase, ubiquitin aldehyde binding 1
PACS1 phosphofurin acidic cluster sorting protein 1
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
PCDHGB6 protocadherin gamma subfamily B, 6
PDE2A phosphodiesterase 2A, cGMP-stimulated
PGAM2 phosphoglycerate mutase 2 (muscle)
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta
PLCE1 phospholipase C, epsilon 1
PLD1 phospholipase D1, phosphatidylcholine-specific
PLK4 polo-like kinase 4
PRAMEF11 PRAME family member 11
PTGDR2 prostaglandin D2 receptor 2
RAB6A RAB6A, member RAS oncogene family
RAPSN receptor-associated protein of the synapse
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RGS12 regulator of G-protein signaling 12
RNF122 ring finger protein 122
RPGRIP1L RPGRIP1-like
SAA4 serum amyloid A4, constitutive
SHOX2 short stature homeobox 2
SIM2 single-minded family bHLH transcription factor 2
SOGA1 suppressor of glucose, autophagy associated 1
SOX15 SRY (sex determining region Y)-box 15
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding)
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2
SYN3 synapsin III
TBL2 transducin (beta)-like 2
TMEM19 transmembrane protein 19
TP53I11 tumor protein p53 inducible protein 11
TRBC1 T cell receptor beta constant 1
TRD T cell receptor delta locus
TRPC5 transient receptor potential cation channel, subfamily C, member 5
UPK3B uroplakin 3B
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
VPS41 vacuolar protein sorting 41 homolog (S. cerevisiae)
WDR25 WD repeat domain 25
ZFHX4 zinc finger homeobox 4
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF132 zinc finger protein 132
ZNF492 zinc finger protein 492
ZNF675 zinc finger protein 675
ZNF710 zinc finger protein 710
ZXDB zinc finger, X-linked, duplicated B

decreased expression

Symbol Name
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ACPP acid phosphatase, prostate
ALS2CL ALS2 C-terminal like
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ATHL1 ATH1, acid trehalase-like 1 (yeast)
BACE1 beta-site APP-cleaving enzyme 1
BBS7 Bardet-Biedl syndrome 7
BGLAP bone gamma-carboxyglutamate (gla) protein
BPI bactericidal/permeability-increasing protein
C16ORF59 chromosome 16 open reading frame 59
C17ORF53 chromosome 17 open reading frame 53
C1ORF159 chromosome 1 open reading frame 159
C22ORF46 chromosome 22 open reading frame 46
CBX7 chromobox homolog 7
CD82 CD82 molecule
CEP170B centrosomal protein 170B
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CIR1 corepressor interacting with RBPJ, 1
CLCN2 chloride channel, voltage-sensitive 2
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
CRELD1 cysteine-rich with EGF-like domains 1
CRY2 cryptochrome circadian clock 2
CTC1 CTS telomere maintenance complex component 1
CTSV cathepsin V
CUL9 cullin 9
DFNA5 deafness, autosomal dominant 5
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DSPP dentin sialophosphoprotein
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
F3 coagulation factor III (thromboplastin, tissue factor)
FAM127B family with sequence similarity 127, member B
FAM63A family with sequence similarity 63, member A
FRS3 fibroblast growth factor receptor substrate 3
FSTL3 follistatin-like 3 (secreted glycoprotein)
FURIN furin (paired basic amino acid cleaving enzyme)
GIPC1 GIPC PDZ domain containing family, member 1
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GPR20 G protein-coupled receptor 20
GRIP2 glutamate receptor interacting protein 2
GTF2I general transcription factor IIi
HIST1H2AI histone cluster 1, H2ai
HOXC8 homeobox C8
ICAM5 intercellular adhesion molecule 5, telencephalin
IQCG IQ motif containing G
IRS1 insulin receptor substrate 1
KLHL28 kelch-like family member 28
LIMD2 LIM domain containing 2
LRRC23 leucine rich repeat containing 23
LYPLA2P1 lysophospholipase II pseudogene 1
LZTS3 leucine zipper, putative tumor suppressor family member 3
MCTP2 multiple C2 domains, transmembrane 2
MYBPH myosin binding protein H
NCKAP1L NCK-associated protein 1-like
NINJ2 ninjurin 2
NIPAL2 NIPA-like domain containing 2
NUPR1 nuclear protein, transcriptional regulator, 1
OLFML2A olfactomedin-like 2A
OPLAH 5-oxoprolinase (ATP-hydrolysing)
OXCT2 3-oxoacid CoA transferase 2
PADI1 peptidyl arginine deiminase, type I
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PCSK7 proprotein convertase subtilisin/kexin type 7
PDE12 phosphodiesterase 12
PDGFD platelet derived growth factor D
PHACTR1 phosphatase and actin regulator 1
PIAS3 protein inhibitor of activated STAT, 3
PPFIA4 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
PRKAG1 protein kinase, AMP-activated, gamma 1 non-catalytic subunit
PTDSS2 phosphatidylserine synthase 2
PTPRS protein tyrosine phosphatase, receptor type, S
QPCTL glutaminyl-peptide cyclotransferase-like
SCAMP4 secretory carrier membrane protein 4
SETD8 SET domain containing (lysine methyltransferase) 8
SIGLEC15 sialic acid binding Ig-like lectin 15
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
SSBP3 single stranded DNA binding protein 3
STARD3 StAR-related lipid transfer (START) domain containing 3
TESK1 testis-specific kinase 1
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TMEM209 transmembrane protein 209
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TNRC6B trinucleotide repeat containing 6B
TRAF2 TNF receptor-associated factor 2
TRIM36 tripartite motif containing 36
TRPS1 trichorhinophalangeal syndrome I
TUBA3C tubulin, alpha 3c
UPK3A uroplakin 3A
USB1 U6 snRNA biogenesis 1
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VILL villin-like
WNT16 wingless-type MMTV integration site family, member 16
ZNF254 zinc finger protein 254
ZNF510 zinc finger protein 510
ZNF552 zinc finger protein 552
ZNF671 zinc finger protein 671
ZNF816 zinc finger protein 816
ZSCAN31 zinc finger and SCAN domain containing 31