butoconazole-3288 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the butoconazole-3288 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AFF3 AF4/FMR2 family, member 3
AKAP7 A kinase (PRKA) anchor protein 7
AKR1C1 aldo-keto reductase family 1, member C1
APAF1 apoptotic peptidase activating factor 1
ARFRP1 ADP-ribosylation factor related protein 1
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ATF3 activating transcription factor 3
BGN biglycan
BTF3P11 basic transcription factor 3 pseudogene 11
CAMK4 calcium/calmodulin-dependent protein kinase IV
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CDC14B cell division cycle 14B
CDO1 cysteine dioxygenase type 1
CDRT1 CMT1A duplicated region transcript 1
CFLAR CASP8 and FADD-like apoptosis regulator
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
CLCN6 chloride channel, voltage-sensitive 6
COL19A1 collagen, type XIX, alpha 1
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CRH corticotropin releasing hormone
CSF1 colony stimulating factor 1 (macrophage)
DBF4B DBF4 zinc finger B
DCTN1 dynactin 1
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DOK4 docking protein 4
DSC2 desmocollin 2
DUSP9 dual specificity phosphatase 9
E2F5 E2F transcription factor 5, p130-binding
EFR3B EFR3 homolog B (S. cerevisiae)
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2
ERO1LB ERO1-like beta (S. cerevisiae)
FLI1 Fli-1 proto-oncogene, ETS transcription factor
FOSL2 FOS-like antigen 2
FSCN1 fascin actin-bundling protein 1
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GPRIN2 G protein regulated inducer of neurite outgrowth 2
HCAR3 hydroxycarboxylic acid receptor 3
HDAC6 histone deacetylase 6
HFE hemochromatosis
HIST1H3E histone cluster 1, H3e
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2
HR hair growth associated
ICAM5 intercellular adhesion molecule 5, telencephalin
IDUA iduronidase, alpha-L-
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
INHBE inhibin, beta E
KCNA4 potassium channel, voltage gated shaker related subfamily A, member 4
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KLHL24 kelch-like family member 24
KRT16 keratin 16, type I
KRT17 keratin 17, type I
KRT33A keratin 33A, type I
LARP7 La ribonucleoprotein domain family, member 7
LAT2 linker for activation of T cells family, member 2
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LY6G6C lymphocyte antigen 6 complex, locus G6C
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MR1 major histocompatibility complex, class I-related
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
MYF5 myogenic factor 5
N4BP3 NEDD4 binding protein 3
NNAT neuronatin
NPFFR1 neuropeptide FF receptor 1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
NUPR1 nuclear protein, transcriptional regulator, 1
OASL 2'-5'-oligoadenylate synthetase-like
PI15 peptidase inhibitor 15
PIPOX pipecolic acid oxidase
PLCH1 phospholipase C, eta 1
PLTP phospholipid transfer protein
PPP1R9A protein phosphatase 1, regulatory subunit 9A
PPP4R4 protein phosphatase 4, regulatory subunit 4
PRB1 proline-rich protein BstNI subfamily 1
PTCRA pre T-cell antigen receptor alpha
PTGIS prostaglandin I2 (prostacyclin) synthase
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RECQL5 RecQ protein-like 5
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RERE arginine-glutamic acid dipeptide (RE) repeats
SAPCD1 suppressor APC domain containing 1
SLC17A2 solute carrier family 17, member 2
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLCO1C1 solute carrier organic anion transporter family, member 1C1
SLIT2 slit homolog 2 (Drosophila)
SPTBN1 spectrin, beta, non-erythrocytic 1
SRCAP Snf2-related CREBBP activator protein
SYNE1 spectrin repeat containing, nuclear envelope 1
TM4SF5 transmembrane 4 L six family member 5
TMEM59L transmembrane protein 59-like
TRIM2 tripartite motif containing 2
TRPC1 transient receptor potential cation channel, subfamily C, member 1
WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1
WSCD1 WSC domain containing 1
ZBTB22 zinc finger and BTB domain containing 22
ZNF235 zinc finger protein 235
ZNF778 zinc finger protein 778

decreased expression

Symbol Name
ACTL8 actin-like 8
ADGRL2 adhesion G protein-coupled receptor L2
AKIP1 A kinase (PRKA) interacting protein 1
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ALPK1 alpha-kinase 1
ARMC4 armadillo repeat containing 4
ARSB arylsulfatase B
ASPHD1 aspartate beta-hydroxylase domain containing 1
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BCOR BCL6 corepressor
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
C1ORF35 chromosome 1 open reading frame 35
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CBX8 chromobox homolog 8
CCDC85C coiled-coil domain containing 85C
CCNO cyclin O
CGREF1 cell growth regulator with EF-hand domain 1
CLK1 CDC-like kinase 1
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CLSPN claspin
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DLEU2 deleted in lymphocytic leukemia 2 (non-protein coding)
ERN2 endoplasmic reticulum to nucleus signaling 2
EVA1B eva-1 homolog B (C. elegans)
F8 coagulation factor VIII, procoagulant component
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase)
FBXO22 F-box protein 22
FBXO5 F-box protein 5
FOXN2 forkhead box N2
GAMT guanidinoacetate N-methyltransferase
GAREM GRB2 associated, regulator of MAPK1
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GLCE glucuronic acid epimerase
GRTP1 growth hormone regulated TBC protein 1
GRWD1 glutamate-rich WD repeat containing 1
GSTCD glutathione S-transferase, C-terminal domain containing
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HIST2H2AA3 histone cluster 2, H2aa3
IFT140 intraflagellar transport 140
IL12RB1 interleukin 12 receptor, beta 1
INF2 inverted formin, FH2 and WH2 domain containing
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KIAA0754 KIAA0754
KIAA1551 KIAA1551
LGALS4 lectin, galactoside-binding, soluble, 4
LHX6 LIM homeobox 6
LOC390998 ribosomal protein L10 pseudogene
LRRC61 leucine rich repeat containing 61
LY6D lymphocyte antigen 6 complex, locus D
MED9 mediator complex subunit 9
MON1B MON1 secretory trafficking family member B
MSANTD2 Myb/SANT-like DNA-binding domain containing 2
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric
NFE2L3 nuclear factor, erythroid 2-like 3
NPY1R neuropeptide Y receptor Y1
NUP62CL nucleoporin 62kDa C-terminal like
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PCDHB13 protocadherin beta 13
PCSK7 proprotein convertase subtilisin/kexin type 7
PDZRN3 PDZ domain containing ring finger 3
PES1 pescadillo ribosomal biogenesis factor 1
PGP phosphoglycolate phosphatase
PHC1 polyhomeotic homolog 1 (Drosophila)
PITX2 paired-like homeodomain 2
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PLEKHO1 pleckstrin homology domain containing, family O member 1
POMT2 protein-O-mannosyltransferase 2
POTEKP POTE ankyrin domain family, member K, pseudogene
PTDSS2 phosphatidylserine synthase 2
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RNF170 ring finger protein 170
RPS14P3 ribosomal protein S14 pseudogene 3
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
SCRIB scribbled planar cell polarity protein
SECTM1 secreted and transmembrane 1
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SETD1A SET domain containing 1A
SETD1B SET domain containing 1B
SLC10A3 solute carrier family 10, member 3
SLC12A8 solute carrier family 12, member 8
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TFF2 trefoil factor 2
TOM1 target of myb1 (chicken)
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
UBXN6 UBX domain protein 6
YEATS2 YEATS domain containing 2
ZBTB44 zinc finger and BTB domain containing 44
ZBTB6 zinc finger and BTB domain containing 6
ZFP30 ZFP30 zinc finger protein
ZNF107 zinc finger protein 107
ZNF324 zinc finger protein 324
ZNF37BP zinc finger protein 37B, pseudogene
ZNF408 zinc finger protein 408
ZNF552 zinc finger protein 552