butyl hydroxybenzoate-4647 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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199 genes differentially expressed following the butyl hydroxybenzoate-4647 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAGAB alpha- and gamma-adaptin binding protein
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
AGXT alanine-glyoxylate aminotransferase
AKAP5 A kinase (PRKA) anchor protein 5
ALOX15B arachidonate 15-lipoxygenase, type B
ANGPT4 angiopoietin 4
ASPHD1 aspartate beta-hydroxylase domain containing 1
CACFD1 calcium channel flower domain containing 1
CACYBP calcyclin binding protein
CCL19 chemokine (C-C motif) ligand 19
CD163 CD163 molecule
CD300A CD300a molecule
CDHR5 cadherin-related family member 5
CLEC4A C-type lectin domain family 4, member A
COL9A3 collagen, type IX, alpha 3
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CPN2 carboxypeptidase N, polypeptide 2
CRLF2 cytokine receptor-like factor 2
CRYGC crystallin, gamma C
CSHL1 chorionic somatomammotropin hormone-like 1
CXCL13 chemokine (C-X-C motif) ligand 13
CXCR2 chemokine (C-X-C motif) receptor 2
CXCR6 chemokine (C-X-C motif) receptor 6
CYP3A7 cytochrome P450, family 3, subfamily A, polypeptide 7
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
DAB1 Dab, reelin signal transducer, homolog 1 (Drosophila)
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
F7 coagulation factor VII (serum prothrombin conversion accelerator)
FCAR Fc fragment of IgA receptor
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
FOXO4 forkhead box O4
FYB FYN binding protein
G6PC glucose-6-phosphatase, catalytic subunit
GALR2 galanin receptor 2
GHRHR growth hormone releasing hormone receptor
GLI2 GLI family zinc finger 2
HLF hepatic leukemia factor
HSPA12A heat shock 70kDa protein 12A
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
IFNA8 interferon, alpha 8
IGL immunoglobulin lambda locus
IL36RN interleukin 36 receptor antagonist
IL5RA interleukin 5 receptor, alpha
IQCC IQ motif containing C
IRAK3 interleukin-1 receptor-associated kinase 3
ITGB5 integrin, beta 5
KCNE2 potassium channel, voltage gated subfamily E regulatory beta subunit 2
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KCNH1 potassium channel, voltage gated eag related subfamily H, member 1
KLK13 kallikrein-related peptidase 13
KRT14 keratin 14, type I
LARGE like-glycosyltransferase
MATN3 matrilin 3
MGAT3 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
MMP24 matrix metallopeptidase 24 (membrane-inserted)
MUC4 mucin 4, cell surface associated
NCR2 natural cytotoxicity triggering receptor 2
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
OSBPL7 oxysterol binding protein-like 7
PARP8 poly (ADP-ribose) polymerase family, member 8
PCDHB13 protocadherin beta 13
PCDHGA11 protocadherin gamma subfamily A, 11
PCYT1B phosphate cytidylyltransferase 1, choline, beta
PKLR pyruvate kinase, liver and RBC
PMFBP1 polyamine modulated factor 1 binding protein 1
POM121L9P POM121 transmembrane nucleoporin-like 9, pseudogene
POU1F1 POU class 1 homeobox 1
PTPN12 protein tyrosine phosphatase, non-receptor type 12
PYY peptide YY
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RGS6 regulator of G-protein signaling 6
S1PR1 sphingosine-1-phosphate receptor 1
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SEZ6L seizure related 6 homolog (mouse)-like
SIGLEC8 sialic acid binding Ig-like lectin 8
SLA Src-like-adaptor
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
SOX2 SRY (sex determining region Y)-box 2
SPI1 Spi-1 proto-oncogene
SPINK5 serine peptidase inhibitor, Kazal type 5
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
STK3 serine/threonine kinase 3
STX7 syntaxin 7
SUGP1 SURP and G patch domain containing 1
SWAP70 SWAP switching B-cell complex 70kDa subunit
TAF1C TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa
TEF thyrotrophic embryonic factor
TLN2 talin 2
TMEM140 transmembrane protein 140
TRAF3IP3 TRAF3 interacting protein 3
TRD T cell receptor delta locus
VWA5A von Willebrand factor A domain containing 5A
WSB1 WD repeat and SOCS box containing 1
ZHX3 zinc fingers and homeoboxes 3

decreased expression

Symbol Name
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ADCY6 adenylate cyclase 6
AFAP1 actin filament associated protein 1
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11
ARRB2 arrestin, beta 2
BAK1 BCL2-antagonist/killer 1
C4ORF19 chromosome 4 open reading frame 19
CA9 carbonic anhydrase IX
CCDC6 coiled-coil domain containing 6
CDK3 cyclin-dependent kinase 3
CDT1 chromatin licensing and DNA replication factor 1
CEP112 centrosomal protein 112kDa
CHM choroideremia (Rab escort protein 1)
CLDN4 claudin 4
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
DCAF4 DDB1 and CUL4 associated factor 4
ERCC5 excision repair cross-complementation group 5
ERF Ets2 repressor factor
ETNK2 ethanolamine kinase 2
EXOC5 exocyst complex component 5
FBXW12 F-box and WD repeat domain containing 12
FGD1 FYVE, RhoGEF and PH domain containing 1
FKBP1B FK506 binding protein 1B, 12.6 kDa
FNTB farnesyltransferase, CAAX box, beta
FZD8 frizzled class receptor 8
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GPATCH2L G patch domain containing 2-like
GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
GPRASP1 G protein-coupled receptor associated sorting protein 1
HIRA histone cell cycle regulator
HOXA4 homeobox A4
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IGSF3 immunoglobulin superfamily, member 3
INCENP inner centromere protein antigens 135/155kDa
INF2 inverted formin, FH2 and WH2 domain containing
IPO8 importin 8
JUNB jun B proto-oncogene
KCTD20 potassium channel tetramerization domain containing 20
KDM7A lysine (K)-specific demethylase 7A
KIAA0753 KIAA0753
KIFC1 kinesin family member C1
KRT8P12 keratin 8 pseudogene 12
LIG4 ligase IV, DNA, ATP-dependent
LZTR1 leucine-zipper-like transcription regulator 1
MAN2C1 mannosidase, alpha, class 2C, member 1
MBTD1 mbt domain containing 1
MBTPS2 membrane-bound transcription factor peptidase, site 2
MFGE8 milk fat globule-EGF factor 8 protein
MOCS3 molybdenum cofactor synthesis 3
MOSPD3 motile sperm domain containing 3
MPI mannose phosphate isomerase
NDP Norrie disease (pseudoglioma)
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NPFFR1 neuropeptide FF receptor 1
NUS1P3 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PARM1 prostate androgen-regulated mucin-like protein 1
PARP3 poly (ADP-ribose) polymerase family, member 3
PHC1 polyhomeotic homolog 1 (Drosophila)
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLCD1 phospholipase C, delta 1
PLEKHO1 pleckstrin homology domain containing, family O member 1
POMT2 protein-O-mannosyltransferase 2
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRR4 proline rich 4 (lacrimal)
ROM1 retinal outer segment membrane protein 1
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SARS2 seryl-tRNA synthetase 2, mitochondrial
SCYL2 SCY1-like 2 (S. cerevisiae)
SEC14L2 SEC14-like 2 (S. cerevisiae)
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
SETD6 SET domain containing 6
SIX1 SIX homeobox 1
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SNTA1 syntrophin, alpha 1
STAC SH3 and cysteine rich domain
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMBIM1 transmembrane BAX inhibitor motif containing 1
TMEM51 transmembrane protein 51
TRAPPC13 trafficking protein particle complex 13
TWSG1 twisted gastrulation BMP signaling modulator 1
TXLNG taxilin gamma
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF16 zinc finger protein 16
ZNF227 zinc finger protein 227
ZNF552 zinc finger protein 552
ZNF711 zinc finger protein 711
ZNF76 zinc finger protein 76
ZNRD1-AS1 ZNRD1 antisense RNA 1